LOCUS       NM_001382837            2589 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus sulfotransferase family 1B, member 1 (Sult1b1),
            transcript variant 3, mRNA.
ACCESSION   NM_001382837 XM_006535150
VERSION     NM_001382837.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2589)
  AUTHORS   Xu,X., Patrakka,J., Sistani,L., Uhlen,M., Jalanko,H., Betsholtz,C.
            and Tryggvason,K.
  TITLE     Expression of novel podocyte-associated proteins sult1b1 and
            ankrd25
  JOURNAL   Nephron Exp Nephrol 117 (2), e39-e46 (2011)
   PUBMED   20720434
  REMARK    GeneRIF: sult1b1 may be involved in the sulfonylation of podocyte
            protein podocalyxin, whereas ankrd25 may contribute to controlling
            actin dynamics in podocyte foot processes.
REFERENCE   3  (bases 1 to 2589)
  AUTHORS   Senggunprai,L., Yoshinari,K. and Yamazoe,Y.
  TITLE     Inhibitory effects of kynurenic acid, a tryptophan metabolite, and
            its derivatives on cytosolic sulfotransferases
  JOURNAL   Biochem J 422 (3), 455-462 (2009)
   PUBMED   19548878
  REMARK    Erratum:[Biochem J. 2009 Nov 1;423(3):442]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2589)
  AUTHORS   Shimada,M., Matsuda,T., Sato,A., Akase,T., Matsubara,T., Nagata,K.
            and Yamazoe,Y.
  TITLE     Expression of a skin cholesterol sulfotransferase, St2b2, is a
            trigger of epidermal cell differentiation
  JOURNAL   Xenobiotica 38 (12), 1487-1499 (2008)
   PUBMED   18979284
REFERENCE   5  (bases 1 to 2589)
  AUTHORS   Senggunprai,L., Yoshinari,K., Shimada,M. and Yamazoe,Y.
  TITLE     Involvement of ST1B subfamily of cytosolic sulfotransferase in
            kynurenine metabolism to form natriuretic xanthurenic acid sulfate
  JOURNAL   J Pharmacol Exp Ther 327 (3), 789-798 (2008)
   PUBMED   18815351
  REMARK    GeneRIF: mSult1b1 is suggested as a major enzyme responsible for XA
            sulfation in jejunum
REFERENCE   6  (bases 1 to 2589)
  AUTHORS   Garrison,W.D., Battle,M.A., Yang,C., Kaestner,K.H., Sladek,F.M. and
            Duncan,S.A.
  TITLE     Hepatocyte nuclear factor 4alpha is essential for embryonic
            development of the mouse colon
  JOURNAL   Gastroenterology 130 (4), 1207-1220 (2006)
   PUBMED   16618389
REFERENCE   7  (bases 1 to 2589)
  AUTHORS   Tsoi,C., Falany,C.N., Morgenstern,R. and Swedmark,S.
  TITLE     Molecular cloning, expression, and characterization of a canine
            sulfotransferase that is a human ST1B2 ortholog
  JOURNAL   Arch Biochem Biophys 390 (1), 87-92 (2001)
   PUBMED   11368519
REFERENCE   8  (bases 1 to 2589)
  AUTHORS   Saeki,Y., Sakakibara,Y., Araki,Y., Yanagisawa,K., Suiko,M.,
            Nakajima,H. and Liu,M.C.
  TITLE     Molecular cloning, expression, and characterization of a novel
            mouse liver SULT1B1 sulfotransferase
  JOURNAL   J Biochem 124 (1), 55-64 (1998)
   PUBMED   9644246
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158917.6.
            
            On May 26, 2020 this sequence version replaced XM_006535150.2.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Variants 1-3 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024361.1, SRR5189673.116266.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               AC158917.6         46927-47150
            225-353             AC158917.6         48058-48186
            354-451             AC158917.6         51401-51498
            452-578             AC158917.6         60475-60601
            579-673             AC158917.6         61208-61302
            674-854             AC158917.6         64611-64791
            855-2589            AC158917.6         67026-68760
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 43.56 cM"
     gene            1..2589
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /note="sulfotransferase family 1B, member 1"
                     /db_xref="GeneID:56362"
                     /db_xref="MGI:MGI:2136282"
     exon            1..224
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /inference="alignment:Splign:2.1.0"
     exon            225..353
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /inference="alignment:Splign:2.1.0"
     exon            354..451
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /inference="alignment:Splign:2.1.0"
     exon            452..578
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /inference="alignment:Splign:2.1.0"
     exon            579..673
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /inference="alignment:Splign:2.1.0"
     exon            674..854
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /inference="alignment:Splign:2.1.0"
     exon            855..2589
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1048..1053
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /note="hexamer: AATAAA"
     polyA_site      1069
                     /gene="Sult1b1"
                     /gene_synonym="ST1B1; St2b2"
                     /note="major polyA site"
ORIGIN      
        1 agtcttaagt ttaacacttg tcacacagaa cctgattttt actccttcta ttccttctgt
       61 tcagcctgct gcaaaaatga gtgcctcaga agacgtttgg agaaaagatc tgaagatgat
      121 ccatggctac cccatgatct atgcttttgc actcaattgg gaaaggattg aagagttcca
      181 gagcacacca ggtgacattg taataaccac ttaccctaaa tcaggtacta cttggcttag
      241 tgagattgta gacatggttc taaatgatgg aaatgttgaa aaatgtaaga gagatgttat
      301 cacctccaaa gttccaatgt tggaactgag tgttcctgga ataagaatat caggtgttga
      361 actcttgaag aaaactccat cacctcggat aataaagaca catcttccaa tcgatctact
      421 cccaaaatcc ttctgggaga acaagtgcaa gatgatttac cttgctcgaa atggcaagga
      481 tgttgctgtc tcctattatc attttgatct gatgaatagt attaatcctc ttcctggcac
      541 ctgggaagaa tatctggaga aattcctagc tggaaatgtg gcctatggtt catggtttga
      601 tcatgttaag agttggtggg aaaagaggga agagcatcct ttactttact tatactatga
      661 agaattgaaa cagaacccaa agaaagaaat caagaagata gccagctttc tagacaagac
      721 cttggatgaa gaggccttgg acaggatcgt ccatcacacc tcctttgaaa tgatgaagga
      781 aaaccccctg gtcaattaca cccatctgcc cacagcaatg atggaccaca gcaagtcccc
      841 tttcatgaga aaaggtattg ttggggactg gaaaaattac ttcacaatga cccaaactga
      901 gcaatttgat gctgtctata agaagaagat gtctggaaca acacttgagt tctgcacaga
      961 cattcagagt gcctaatcta caacttgaat atatggtttc ttaaaatagt aacctggaag
     1021 agaaatcaaa tagattcatg aaggaaaaat aaatgtgctt taaaaatgct aattgaaaac
     1081 atactacaca ttccccagca ggtaatcttc caaatgatct agagccaagg tcttttgtta
     1141 ccttagtttt caaaggatat gtcttcagat ttctagattc ttactgagtt gaataaatac
     1201 attttgtgac ttttgaaaaa aaaagaagtt ggtctgagtt tattataata tggaatataa
     1261 tttgtttcag aatatgaaac atgttcttgc aaaacatatt tcacaggaga ctatactttc
     1321 cactgtgtct cccatgtagt agtacttaga gaaagtactt agagaaagta cttagagaac
     1381 actaagcgct tcttagagtt atgtttcctt cactattaaa acagtttgca aggttgcaaa
     1441 tggtctgcat tttctacact tgttaggttc cctctcctgg atatctgacc caggacacta
     1501 tgctccctgg ctatctcaag gttttcatgc tgttctgtga gttatcaatt atccttctac
     1561 catggttctt cagtaatatt attccatgtg tcagatcaag tagctgagac ttggaaatag
     1621 tgtagaccag gctggcctca aattcggaaa ttcacctacc tctacctccc aagtgctggg
     1681 tttaaaggca tatgccacca tcacctggcc acattatttt gtttagaact tttcccttga
     1741 gctgtgagct tatctctgag aacctattca atctctgccc tattcacgtc cagatatatc
     1801 ttggacagag aaatgtataa ctctttgtgt gaaaaggttt cctgcctgta ggtaatatca
     1861 acctatgtaa aattgtatct caaactgtct ccaaactaaa gcgagttgat gagctctaga
     1921 tttctccttt acctattcaa aagatggagg cttcatttac aatgtaaaca cactctcaac
     1981 catagctgat atgagaatag gtaaaagaat ttgtattttt acaagtgagt cttagctaca
     2041 agtccttgtt tcaacttcaa agaaagtcat ccagtacaag tgcaaactca cagaaaatac
     2101 acatctttgc ttagagagat agctgcttca taacatggtt tataatttct tcaagttatg
     2161 aaacatgtgt tctaatgcta agaaatatct tgtagaagtt atataaaata tttgtaggta
     2221 tgaaaatata atttgacttg gagaatattc ttctcaggaa aaaaattaag ccaatgtagg
     2281 cagatactta atttgcctta ttatcaatac caataagtta atgtgaccca caatctgata
     2341 caacctcaag ttataggaaa aaataataag catctgtgac ctagactaat tttgttgtaa
     2401 tggcttgctt gaatcatcta ccttcactag tacaatgaag taactttggc tttccttttc
     2461 aggaattttg tttaattctg ttcaacaata gtaactttat aaacttgaac tattcttcaa
     2521 gtgattttga agtgcaaaaa atataatttg aaaaaaataa agtgtatatt tttctttact
     2581 tttcaaaaa
//
