LOCUS       NM_138654               1727 bp    mRNA    linear   ROD 16-FEB-2025
DEFINITION  Mus musculus succinyl-CoA glutarate-CoA transferase (Sugct), mRNA.
ACCESSION   NM_138654
VERSION     NM_138654.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1727)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1727)
  AUTHORS   Leandro,J., Bender,A., Dodatko,T., Argmann,C., Yu,C. and
            Houten,S.M.
  TITLE     Glutaric aciduria type 3 is a naturally occurring biochemical trait
            in inbred mice of 129 substrains
  JOURNAL   Mol Genet Metab 132 (2), 139-145 (2021)
   PUBMED   33483254
  REMARK    GeneRIF: Glutaric aciduria type 3 is a naturally occurring
            biochemical trait in inbred mice of 129 substrains.
REFERENCE   3  (bases 1 to 1727)
  AUTHORS   Niska-Blakie,J., Gopinathan,L., Low,K.N., Kien,Y.L., Goh,C.M.F.,
            Caldez,M.J., Pfeiffenberger,E., Jones,O.S., Ong,C.B.,
            Kurochkin,I.V., Coppola,V., Tessarollo,L., Choi,H.,
            Kanagasundaram,Y., Eisenhaber,F., Maurer-Stroh,S. and Kaldis,P.
  TITLE     Knockout of the non-essential gene SUGCT creates diet-linked,
            age-related microbiome disbalance with a diabetes-like metabolic
            syndrome phenotype
  JOURNAL   Cell Mol Life Sci 77 (17), 3423-3439 (2020)
   PUBMED   31722069
  REMARK    GeneRIF: Knockout of the non-essential gene SUGCT creates
            diet-linked, age-related microbiome disbalance with a diabetes-like
            metabolic syndrome phenotype.
REFERENCE   4  (bases 1 to 1727)
  AUTHORS   Nakabayashi,K., Fernandez,B.A., Teshima,I., Shuman,C., Proud,V.K.,
            Curry,C.J., Chitayat,D., Grebe,T., Ming,J., Oshimura,M., Meguro,M.,
            Mitsuya,K., Deb-Rinker,P., Herbrick,J.A., Weksberg,R. and
            Scherer,S.W.
  TITLE     Molecular genetic studies of human chromosome 7 in Russell-Silver
            syndrome
  JOURNAL   Genomics 79 (2), 186-196 (2002)
   PUBMED   11829489
REFERENCE   5  (bases 1 to 1727)
  AUTHORS   Kawamoto,S., Matsumoto,Y., Mizuno,K., Okubo,K. and Matsubara,K.
  TITLE     Expression profiles of active genes in human and mouse livers
  JOURNAL   Gene 174 (1), 151-158 (1996)
   PUBMED   8863742
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ068463.1, AK160265.1, AA108199.1 and AC154368.3.
            
            On Oct 16, 2009 this sequence version replaced NM_138654.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055852.1, SRR7345562.964928.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-399               CJ068463.1         3-401
            400-724             AK160265.1         273-597
            725-945             AA108199.1         177-397
            946-1718            AK160265.1         819-1591
            1719-1727           AC154368.3         87504-87512
FEATURES             Location/Qualifiers
     source          1..1727
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 5.92 cM"
     gene            1..1727
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /note="succinyl-CoA glutarate-CoA transferase"
                     /db_xref="GeneID:192136"
                     /db_xref="MGI:MGI:1923221"
     exon            1..127
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1344
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /EC_number="2.8.3.13"
                     /note="succinate--hydroxymethylglutarate CoA-transferase;
                     succinylCoA:glutarate-CoA transferase;
                     dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase
                     SUGCT"
                     /codon_start=1
                     /product="succinyl-CoA:glutarate CoA-transferase"
                     /protein_id="NP_619595.3"
                     /db_xref="CCDS:CCDS26252.1"
                     /db_xref="GeneID:192136"
                     /db_xref="MGI:MGI:1923221"
                     /translation="MLWMLARAVAFRRPGRGLAGGRGLWTGRPQSDCDSMKPLEGVRI
                     LDLTRVLAGPFATMNLGDLGAEVIKVERPGAGDDTRSWGPPFVNTESTYFLSVNRNKK
                     SIAVNIKDPRGVRIVKELAAICDVFVENYVPGKLSEMGLGYEDIDKIAPHIIYCSITG
                     YGQTGPMSHRAGYDAIASAMSGLMHITGPEDGDPVRPGVAMTDLATGLFAYGAIMAGL
                     LQRYRTGKGLFIDCNLLSSQVACLTQVAANYLIGQKEAKRWGTAHGSIVPYQAFKTKD
                     GYLVIGAGNNQQFAVVCKILNLPELIDDCKYRTNHLRVQNRKELVKILSARFAEEVTA
                     KWLCLFEGSGIPYGPINSLKDVFSEAQVLHNGLVMEMNHPTVGKISVPGPAVRYSKFK
                     MSEAKPPPLLGQHTRHILKEVLRYDEGAIEKLLCSGVIEQHETK"
     exon            128..179
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            180..253
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            254..339
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            340..390
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            391..511
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            512..603
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            604..747
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            748..843
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            844..915
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1013
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1116
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1180
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..1727
                     /gene="Sugct"
                     /gene_synonym="5033411D12Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcgcggggc gctctcgctg gggttgaggg gcgatgctgt ggatgctggc cagggcggtg
       61 gcttttcgga gacccggccg aggcctggcc ggcgggaggg ggctgtggac cggccgcccg
      121 cagtcagatt gtgacagtat gaagcccctg gagggtgtga gaattctgga tctaacaaga
      181 gtactggcag gaccctttgc cacgatgaat ttaggagatc ttggagcaga agttataaaa
      241 gttgaaagac caggagctgg tgatgacaca cgatcttggg gacctccttt tgtgaacact
      301 gaaagtacat attttcttag tgttaatcga aataaaaaaa gtatagctgt taatatcaag
      361 gatccaagag gagtgagaat cgtcaaagag cttgcagcca tttgtgatgt gtttgtggaa
      421 aactatgttc ctgggaaact ttctgagatg ggcctaggat atgaagatat agataagatt
      481 gctcctcaca tcatctactg ctccatcaca ggatatggcc agacagggcc catgtctcac
      541 agagcaggtt atgatgctat tgcttctgct atgtctggtc taatgcacat cacaggacct
      601 gaggatggag atcctgttcg ccctggagtg gccatgactg acctcgccac tggtcttttt
      661 gcttatgggg ccattatggc tggcctccta caacgttata gaactggaaa aggactgttc
      721 attgattgta atctgctgtc atcacaggtg gcatgtttga cccaagtagc tgctaattat
      781 cttattggac aaaaggaagc gaaacgctgg ggcacagctc atggcagtat tgttccttat
      841 caggctttta aaaccaagga tggctatctt gtaattggag caggaaataa ccaacagttt
      901 gctgtggtat gcaagatctt gaatttgcct gaactgatcg atgattgcaa gtatagaacg
      961 aaccatcttc gggtacagaa tagaaaagag cttgtgaaaa tcctttcagc acggtttgca
     1021 gaagaagtga ctgccaagtg gctttgtctc tttgaaggaa gtgggatccc atatggacca
     1081 atcaacagcc tgaaggatgt gttttcagaa gcccaggtat tgcacaatgg ccttgttatg
     1141 gagatgaatc atccaactgt ggggaagatt tcagtcccag gtccagctgt gagatacagc
     1201 aagttcaaga tgtcagaggc aaagccacct cccctgctgg gacagcatac aaggcatatc
     1261 ctgaaggagg tcctcagata tgatgagggg gctattgaga agctactctg ctctggtgtg
     1321 atagagcaac atgaaaccaa gtgacagagg agaatgcatc agaaaactgc agctggctgg
     1381 cccagacagt gagtgctctg tgcatgcctt tcccagtctt gatcctacta caaagcatgg
     1441 tgaggagaac tacagactac ctgcctggca tctctggggt aactttagga ttaaagtcta
     1501 gtgcccattt aaaaacttac tgttttgact tttcccccca gaaaataatt taatcattga
     1561 tttatggaat ttgattaatt ctatattttt catcctaaag gtataataac tggtgttgga
     1621 atgttgcttt catttaattc ttccacaatg tataatgtat ggaaacatca aattataaat
     1681 tgtagttttg atttgtcaat tgaaaataaa gcaaaaccta aaaaaaa
//
