LOCUS       NM_001160049            4038 bp    mRNA    linear   ROD 17-JUN-2024
DEFINITION  Mus musculus serine/threonine/tyrosine interacting like 2 (Styxl2),
            transcript variant 2, mRNA.
ACCESSION   NM_001160049
VERSION     NM_001160049.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4038)
  AUTHORS   Chen,X., Li,Y., Xu,J., Cui,Y., Wu,Q., Yin,H., Li,Y., Gao,C.,
            Jiang,L., Wang,H., Wen,Z., Yao,Z. and Wu,Z.
  TITLE     Styxl2 regulates de novo sarcomere assembly by binding to
            non-muscle myosin IIs and promoting their degradation
  JOURNAL   Elife 12, 87434 (2024)
   PUBMED   38829202
  REMARK    GeneRIF: Styxl2 regulates de novo sarcomere assembly by binding to
            non-muscle myosin IIs and promoting their degradation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4038)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 4038)
  AUTHORS   Roma-Mateo,C., Rios,P., Tabernero,L., Attwood,T.K. and Pulido,R.
  TITLE     A novel phosphatase family, structurally related to
            dual-specificity phosphatases, that displays unique amino acid
            sequence and substrate specificity
  JOURNAL   J Mol Biol 374 (4), 899-909 (2007)
   PUBMED   17976645
REFERENCE   4  (bases 1 to 4038)
  AUTHORS   Kuninger,D., Kuzmickas,R., Peng,B., Pintar,J.E. and Rotwein,P.
  TITLE     Gene discovery by microarray: identification of novel genes induced
            during growth factor-mediated muscle cell survival and
            differentiation
  JOURNAL   Genomics 84 (5), 876-889 (2004)
   PUBMED   15475267
REFERENCE   5  (bases 1 to 4038)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK048603.1, AK142263.1 and BC059034.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Variants 1 and 2 both encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC117936.1, AK048603.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2693              AK048603.1         28-2720
            2694-4016           AK142263.1         2699-4021
            4017-4038           BC059034.1         3370-3391
FEATURES             Location/Qualifiers
     source          1..4038
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 73.45 cM"
     gene            1..4038
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /note="serine/threonine/tyrosine interacting like 2"
                     /db_xref="GeneID:240892"
                     /db_xref="MGI:MGI:2685055"
     exon            1..107
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /inference="alignment:Splign:2.1.0"
     exon            108..237
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /inference="alignment:Splign:2.1.0"
     exon            238..332
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /inference="alignment:Splign:2.1.0"
     exon            333..564
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /inference="alignment:Splign:2.1.0"
     exon            565..782
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /inference="alignment:Splign:2.1.0"
     exon            783..4021
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3998..4003
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /note="hexamer: ATTAAA"
     polyA_site      4021
                     /gene="Styxl2"
                     /gene_synonym="C130085G02Rik; Dusp27; Gm209"
                     /note="major polyA site"
ORIGIN      
        1 agagcagaag cacaccagag aagagaaagc tcccgtccct ctctagacca aacttctggt
       61 cactttcctg gggttcttgg tccttggtga ggacacacca gcacaagaca gaggctgaca
      121 ggctgacatg gctaccggtg gagacgcaga ggaggagcag gtagttccaa acgaggagga
      181 tgaagcagat gtgagagctg tacaggcccg ctatctccgg agtccctccc caagccagta
      241 ctcggtggtc tcagaggcag aaaccgaaag catcttcatg gagcccatcc acctctcctc
      301 ggctgtagct gccaaacaga tcatcaacga agaactcaag cctcgggggc tcagaacaga
      361 cactgagtgt ccaggcatgc tggagtctgc tgaacaactg ctggtggaag acctgtacaa
      421 ccgtgtccgt gagaagatgg atgacaggag cctgttcaac accccctgtg tgctggacct
      481 gcagcgggcg ctgacccagg accggcaaga ggcccctcgg aatgaggtgg atgaggtgtg
      541 gcccaacgtc ttcatagctg agaaaagcgt ggctgtgaac aaggggcggc tcaagaggct
      601 gggcatcacc cacattctga atgccgcaca tggcacagga gtttacactg gttctgaatt
      661 ctacactggc ctggagatcc agtacctggg ggtggaagtg gatgacttcc cagaggtgga
      721 catctcccaa catttccgga aagcagctga gttccttgac gaagctctgc tgacctacag
      781 agggaaagtc ctggtcagca gtgaaatggg tatcagcagg tcagcagtgc tggtggtcgc
      841 ctacctgatg atcttccaca gcatggccat cctggaggcc ttgatgactg tgcgcagaaa
      901 gcgagctatc taccccaatg acggcttcct aaaacaactg cgggagctca atgagaaatt
      961 gatggaggag agggaagagg aggatggtga agaggagtct gaggaagatg ccgggagcat
     1021 gctgggtgct agagtcaatt cactgatggt ggaagaagaa gatgatgcca ctagccacct
     1081 gagtggctcc tccttgggga aggccagcca ggtctccaaa ccagtcactc ttattgatga
     1141 cgaggaggag gagaagaagc tgtatgaaga gtggaggaag gggcagggct tccccaaggg
     1201 ggaggctgct cagggtagaa agggacgtag ctgttctatg tcctcagcac aggatggaga
     1261 cgactgtgag gatgaggatg tagaaaggat aatccaggag tggcagagcc gaaatgagag
     1321 gtaccaagcc aaagggcgcg agcagtggaa ccgggaggaa gaagaggagg aagagaactc
     1381 ctactccagc agaaggcgca gacacaccct aagcgagagc agtgcttctg agagtgtgag
     1441 cagccatgac atccggatcc tgaagcagca actggagagg agcacccaaa gccgccgcgg
     1501 aagataccgc tctgactcgg agtcctcgga gagcacctgg gacatgtgga acgagaggct
     1561 ggtggagatc gagaaggagg ctgcccggaa gtaccgctcc aagagcaaga gggaggagct
     1621 ggatggcgat tgttcagagg cagggggcag ggtccgagag gacgatgagg agagcgtgtt
     1681 gtctgaggcc agctccttct acaacttctg cagtaggaac aaggacaagc tcactcccct
     1741 ggaaaggtgg aagattaaga gaatccaatt tgggtttcac aagaaagact cggaggcggg
     1801 agacgggggc agtgagcatg gtacagaaga ggcagcagca ggagagaaga acctctctga
     1861 tgtcaacctg acagcctacc aggcctggaa gctgaagcac cagaaaaagg tggggagtga
     1921 gaacaaggag gaagtggttg agatgagcaa aggagaagac acggtcttgg ctaagaagag
     1981 acagcggaga ctagagttac tggagaggag caggcagaca ctggaggaga gtcagtccat
     2041 gggaagctgg gaggcagaca gctcaacagc cagcaggagc atccccctgt ctgcattctc
     2101 gtccgcggcc ccttctgtca gtgcggatgg ggacactgcg tcagtactca gcacccagag
     2161 ccaccgttct catgcaagta acatgcccgc cacccccctg cctaacctgc cggtggggcc
     2221 tggagacacc atttccattg ccagtatcca gaactggatt gccaatgtcg tcaatgaaac
     2281 cctcgcccag aagcaaaacg aaatgctctt gttgtcccgc ccaccctctg ttgcaagcat
     2341 gaaggcagct ccagcagcct gcggccttgg gggggatgac cagctctccg tgctcagcac
     2401 ctccctgagt ggctgcttac cacctccaag ccaagggaga cccagctccg acgtgcagtc
     2461 tgtgctgtcc tccaccagct cgctgacctc cagggctgaa ggcagtggga acaaagtgag
     2521 ggggaccagc aagcccatct acagcctctt tgctgacaac gtggacctga aggagcttgg
     2581 ccggaaggag aaagagatgc aaatggagct gcaggagaag atgtccgagt ataaaatgga
     2641 gaagctggcc tctgataaca agcgtagctc tctcttcaag aagaagaagg ccaaggatga
     2701 cgaggacatg agcgtgggtg acagagacga ggacacagac agtgccatcg gaagcttccg
     2761 gtactcctct cgcagtaatt cccagaagcc ggagacagat gcctcctctt ctctggccat
     2821 ctctgatcac tatagaaatg gccgcagcat gggtaacgag atggatagca atattaatac
     2881 gtggctcagt ggcctcagga tggaagaaaa atctcctcct caaagtgatt ggtccggaag
     2941 ttccaggggg aggtatacca ggtcttctct gctccgggaa acagagtcta aatcctgcag
     3001 ttacaagttc tccaaatcta ggtcacagga gcaggacacc tccttccacg aagccaatgg
     3061 tgacactgtg cgaaacacct cacggttctc atcttccacc accaaggagg ccagagagat
     3121 gcacaagttc tctcggtcca cattcagcga gacctcgagc tcccgagagg agagcccaga
     3181 accctatttc ttccgccgga cccctgaacc ctctgatggg gaggagtccc cagagccaag
     3241 gcgtccaaac tggaccaggc ccagggactg ggaagatgta gaagagtcat ctaaatcaga
     3301 cttcgctgag tttggggcca agaggaaatt cacccagagc ttcatgaggt ctgaagagga
     3361 gggagagaag gagaggacag aaaaccgaga ggaagggagg tttgcatctg ggcgtcagtc
     3421 ccagtatcgg agaagcacaa accagcaaga ggaagaagaa atggatgatg aagccatcat
     3481 tgccgcctgg agaaagcggc aagaggaaac cagaaccaaa ctgcaaagga ggagggagga
     3541 ctgagcggaa tgaggccctc cttggagaca ctgggaacac ggaaagaagc catttaacac
     3601 tgggcttggg aacagcttac catgacctgc caagggttat gcaggctctt ccatatgggc
     3661 aaaaatgcaa gcatccaagt agaaagggcc tggacagtag ggtggagaag agacaagagc
     3721 cattcatgcg agccccaaat tctggaccag cttacacttt ctatcaccaa aggccctcta
     3781 agctttcctg tttcccttct aagctttcct gtttcccttc tgcatttggt agtgtccacc
     3841 acagagtgga gaagtgagtc tacaaagcca ctgagaaaga cctgacttgc aggctgtggt
     3901 tctcttcatt gaggtttcgc aatgagaccc aggtgatcca ttctgttgtg attctggcct
     3961 ctccctgcca atgcttgact atcatggctt cttttcaatt aaattgatat gctgtcaaat
     4021 aaaaaaaaaa aaaaaaaa
//
