LOCUS       NM_029659               1677 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus serine/threonine/tyrosine interacting-like 1 (Styxl1),
            transcript variant 1, mRNA.
ACCESSION   NM_029659
VERSION     NM_029659.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1677)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1677)
  AUTHORS   Chen,Y., Luo,M., Tu,H., Qi,Y., Guo,Y., Zhang,X., Cui,Y., Gao,M.,
            Zhou,X., Zhu,T., Zhu,H., Situ,C., Li,Y. and Guo,X.
  TITLE     STYXL1 regulates CCT complex assembly and flagellar tubulin folding
            in sperm formation
  JOURNAL   Nat Commun 15 (1), 44 (2024)
   PUBMED   38168070
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK161310.1, AC083948.3 and BC045148.1.
            
            On Oct 2, 2010 this sequence version replaced NM_029659.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a). Variants 1, 2, and
            3 encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK161310.1, SRR5189685.234794.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-247               AK161310.1         2-248
            248-248             AC083948.3         153948-153948       c
            249-1231            AK161310.1         250-1232
            1232-1677           BC045148.1         1162-1607
FEATURES             Location/Qualifiers
     source          1..1677
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 75.38 cM"
     gene            1..1677
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /note="serine/threonine/tyrosine interacting-like 1"
                     /db_xref="GeneID:76571"
                     /db_xref="MGI:MGI:1923821"
     exon            1..135
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     exon            136..242
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     CDS             140..1105
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /note="isoform a is encoded by transcript variant 1; map
                     kinase phosphatase-like protein MK-STYX; dual specificity
                     phosphatase 24 (putative)"
                     /codon_start=1
                     /product="serine/threonine/tyrosine-interacting-like
                     protein 1 isoform a"
                     /protein_id="NP_083935.3"
                     /db_xref="CCDS:CCDS19745.2"
                     /db_xref="GeneID:76571"
                     /db_xref="MGI:MGI:1923821"
                     /translation="MADLLFCEPTELYNILNQVSKLSRLAEPNYLCLLDVRSKRQYDE
                     SHVITALRVKKRDHQYLIPESVDLECVRYCIVYDSNTSSLELCIRRQLEEEEEEEEVE
                     REDKEEDTELLPGPAVEFGQILIHFTRQPVYVLRGGYECFSGMYHFFRTQKIIWMPQE
                     LDAFQPYPVEILPGRVYLGKISQACNAKMHKDLKIKAHVNISMETTPYFIGNADKLLH
                     IKLEDSPDTLLFDYFRHICHFIELHLRLHSVVLVFSTRGISRSVAAVVALLMHYNEET
                     LKRSWAQVKKCKTNMRPNRAFVAQLLEWEKVLHGEYLTDISEPIY"
     exon            243..304
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     exon            305..470
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     exon            471..616
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     exon            617..762
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     exon            763..860
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     exon            861..973
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1652
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1238
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
     polyA_site      1289
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /note="major polyA site"
     regulatory      1327..1332
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /note="hexamer: AATACA"
     polyA_site      1353
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
     regulatory      1622..1627
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
                     /note="hexamer: ACTAAA"
     polyA_site      1652
                     /gene="Styxl1"
                     /gene_synonym="1700011C14Rik; Dusp24; Mkstyx"
ORIGIN      
        1 ccgttagctt tgcccacttc cgggacctag cgctaggaca gacggtcacc aggattaggc
       61 ggaatcttgg gaccgcccct agcaacccgg tactagaagg actcttggag cgctcgcccg
      121 gaggacaggc tctagtagga tggctgacct gcttttctgc gagccaacag aactctataa
      181 catcttgaat caggtctcca agctgtccag attggctgag cccaactacc tctgtttact
      241 ggatgtccga tcaaaacgac agtatgacga gagccatgtg atcactgccc tcagagtgaa
      301 gaagcgagat catcagtacc tcatcccgga gtccgtagac ctggagtgtg tgagatactg
      361 catcgtgtac gacagcaaca ccagttccct ggagctgtgc atacggcggc agctggagga
      421 ggaggaagag gaggaggagg tagaaagaga ggacaaggag gaggacactg aactcctacc
      481 tggacctgct gtggaatttg gacaaatcct cattcacttt acccgccaac ctgtctatgt
      541 cctcagaggg ggctatgaat gcttctctgg catgtaccac ttcttccgga ctcagaagat
      601 catctggatg ccccaggaac tggatgcctt ccagccatac ccagttgaga tacttccagg
      661 cagagtctac ctgggcaaaa tcagtcaagc ctgcaatgct aagatgcaca aggacttgaa
      721 aattaaagca catgtcaata tttccatgga gacaacaccc tattttatag gcaatgcaga
      781 caagctctta catatcaagc ttgaggattc tccagacacc ttgctttttg actatttccg
      841 ccacatctgt cactttatag aacttcacct caggctccac tctgtcgttc tggtcttttc
      901 cacccggggc atcagccgca gcgttgctgc tgtggtggcc ttactcatgc attataatga
      961 ggagacgctg aagaggtcct gggcccaagt gaagaaatgc aaaaccaaca tgcgtccgaa
     1021 tcgggccttc gtggctcagc tgctggagtg ggagaaagtc ctccatgggg aatatctcac
     1081 agacatctcc gagcctatct actgaccttt gcctggaacg cagctatggt cactgaggag
     1141 tcttggttgg gactttgggg gactggggag ctgggtttgc acttggagtg gtcctggaga
     1201 agacctttgc tgcctggagg ttcatatctg catcttaagg ctggttctgt tgttgttgtt
     1261 tttctccaat actgaggatt gaagctagag cagtggttct caaccttcct aacactgcga
     1321 ccctttaata cagtttctca tgtggtgacc tgtcctgagc cgcaggacgg tgaatgagga
     1381 ctggggaatc acctggaaga gaatggggaa acaagaaacg caaagaacgg acagcaagtc
     1441 aaaatctgat caagctgaca gattttattt tttccaggaa ggtttcatac ccaaatagaa
     1501 gcatgatatg gggaggggga tgacgtagag tcactttgtt tctgggggaa tgcacctgtt
     1561 cccaaaagca ggatattggc tgggtacaga aagaacagaa caggttgcta ggtacctgtc
     1621 cactaaaatc tatagctatt tgttctgcct gaaaaaaaaa aaaaaaaaaa aaaaaaa
//
