LOCUS       NM_011505               5983 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus syntaxin binding protein 4 (Stxbp4), mRNA.
ACCESSION   NM_011505 NM_177119
VERSION     NM_011505.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5983)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5983)
  AUTHORS   Tonelli Gombalova,Z., Kosuth,J., Alexovic Matiasova,A.,
            Zrubakova,J., Zezula,I., Giallongo,T., Di Giulio,A.M., Carelli,S.,
            Tomaskova,L., Daxnerova,Z. and Sevc,J.
  TITLE     Majority of cerebrospinal fluid-contacting neurons in the spinal
            cord of C57Bl/6N mice is present in ectopic position unlike in
            other studied experimental mice strains and mammalian species
  JOURNAL   J Comp Neurol 528 (15), 2523-2550 (2020)
   PUBMED   32212159
REFERENCE   3  (bases 1 to 5983)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5983)
  AUTHORS   Hirose,Y., Shirai,K. and Hirai,Y.
  TITLE     Membrane-tethered syntaxin-4 locally abrogates E-cadherin function
            and activates Smad signals, contributing to asymmetric mammary
            epithelial morphogenesis
  JOURNAL   J Cell Biochem 119 (9), 7525-7539 (2018)
   PUBMED   29767852
  REMARK    GeneRIF: Syntaxin-4 directly binds to E-cadherin and activates part
            of Smad signals, leading to the disruption of epithelial
            intercellular adhesion and an augmented expression of fibroblast
            markers. These findings highlight the importance of local membrane
            translocation of syntaxin-4 for spatial epithelial-mesenchymal
            transition in the epithelia and provide new mechanistic insights
            into asymmetric epithelial morphogenesis.
REFERENCE   5  (bases 1 to 5983)
  AUTHORS   Bin,N.R., Ma,K., Harada,H., Tien,C.W., Bergin,F., Sugita,K.,
            Luyben,T.T., Narimatsu,M., Jia,Z., Wrana,J.L., Monnier,P.P.,
            Zhang,L., Okamoto,K. and Sugita,S.
  TITLE     Crucial Role of Postsynaptic Syntaxin 4 in Mediating Basal
            Neurotransmission and Synaptic Plasticity in Hippocampal CA1
            Neurons
  JOURNAL   Cell Rep 23 (10), 2955-2966 (2018)
   PUBMED   29874582
REFERENCE   6  (bases 1 to 5983)
  AUTHORS   Yamada,E., Okada,S., Saito,T., Ohshima,K., Sato,M., Tsuchiya,T.,
            Uehara,Y., Shimizu,H. and Mori,M.
  TITLE     Akt2 phosphorylates Synip to regulate docking and fusion of
            GLUT4-containing vesicles
  JOURNAL   J Cell Biol 168 (6), 921-928 (2005)
   PUBMED   15753124
REFERENCE   7  (bases 1 to 5983)
  AUTHORS   Saito,T., Okada,S., Yamada,E., Ohshima,K., Shimizu,H.,
            Shimomura,K., Sato,M., Pessin,J.E. and Mori,M.
  TITLE     Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate
            insulin secretion in the pancreatic beta HC-9 cell
  JOURNAL   J Biol Chem 278 (38), 36718-36725 (2003)
   PUBMED   12855681
REFERENCE   8  (bases 1 to 5983)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 5983)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   10 (bases 1 to 5983)
  AUTHORS   Min,J., Okada,S., Kanzaki,M., Elmendorf,J.S., Coker,K.J.,
            Ceresa,B.P., Syu,L.J., Noda,Y., Saltiel,A.R. and Pessin,J.E.
  TITLE     Synip: a novel insulin-regulated syntaxin 4-binding protein
            mediating GLUT4 translocation in adipocytes
  JOURNAL   Mol Cell 3 (6), 751-760 (1999)
   PUBMED   10394363
  REMARK    Erratum:[Mol Cell 1999 Jul;4(1):following 142]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL646046.8.
            
            On Dec 21, 2022 this sequence version replaced NM_011505.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.159915.1,
                                           SRR17253014.3334971.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-50                AL646046.8         210981-211030       c
            51-120              AL646046.8         195140-195209       c
            121-248             AL646046.8         194603-194730       c
            249-381             AL646046.8         192131-192263       c
            382-488             AL646046.8         180293-180399       c
            489-705             AL646046.8         179916-180132       c
            706-784             AL646046.8         178901-178979       c
            785-879             AL646046.8         173134-173228       c
            880-976             AL646046.8         167693-167789       c
            977-1068            AL646046.8         165280-165371       c
            1069-1158           AL646046.8         148198-148287       c
            1159-1224           AL646046.8         144670-144735       c
            1225-1401           AL646046.8         121759-121935       c
            1402-1518           AL646046.8         113114-113230       c
            1519-1568           AL646046.8         110859-110908       c
            1569-1702           AL646046.8         108428-108561       c
            1703-1760           AL646046.8         67550-67607         c
            1761-5983           AL646046.8         49440-53662         c
FEATURES             Location/Qualifiers
     source          1..5983
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 55.04 cM"
     gene            1..5983
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /note="syntaxin binding protein 4"
                     /db_xref="GeneID:20913"
                     /db_xref="MGI:MGI:1342296"
     exon            1..50
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            51..120
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            121..248
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..1875
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /note="STX4-interacting protein; syntaxin 4-interacting
                     protein"
                     /codon_start=1
                     /product="syntaxin-binding protein 4"
                     /protein_id="NP_035635.1"
                     /db_xref="CCDS:CCDS25242.1"
                     /db_xref="GeneID:20913"
                     /db_xref="MGI:MGI:1342296"
                     /translation="MSDGTASARSSSPLDRDPAFRVITVTKETGLGLKILGGINRNEG
                     PLVYIHEVIPGGDCYKDGRLKPGDQLVSINKESMIGVSFEEAKSIITRAKLRSESPWE
                     IAFIRQKSYCGHPGNICCPSPQVSEDCGPQTSTFTLLSSPSETLLPKTSSTPQTQDST
                     FPSCKAIQTKPEHDKTEHSPITSLDNSPADTSNADIAPAWTDDDSGPQGKISLNPSVR
                     LKAEKLEMALNYLGIQPTKEQREALREQVQADSKGTVSFGDFVQVARSLFCLQLDEVN
                     VGVHEIPSILDSQLLPCDSLEADEVGKLRQERNAALEERNVLKEKLLESEKHRKQLIE
                     ELQNVKQEAKAVAEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAEVSELKAQL
                     ADYSDQNKESVQDLRKRVTVLDCQLRKSEMARKAFKASTERLLGFIEAIQEVLLDSSA
                     PLSTLSERRAVLASQTSLPLLARNGRSFPATLLLESKELVRSVRAILDMDCLPYGWEE
                     AYTADGIKYFINHVTQTTSWIHPVMSALNLSCAEESEEDCPRELTDPKS"
     exon            249..381
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            382..488
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            489..705
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            706..784
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            785..879
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            880..976
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1068
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1158
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1224
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1401
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1518
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1568
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1702
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1760
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     exon            1761..5983
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5959..5964
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /note="hexamer: TATAAA"
     polyA_site      5983
                     /gene="Stxbp4"
                     /gene_synonym="6030470M02Rik; Synip"
                     /note="major polyA site"
ORIGIN      
        1 agattccaca gttagcagtg gcgctacgga ggccgggtgg cccgaagagg gaaaccagtg
       61 aaatggagta gtatgcacta gagccataca gaatctgcag gaagaccctc gggggagtcg
      121 cctgaggata aaaagaatat ttagactctc caagttcttc ctttacatag ctgctaaatc
      181 caaggaaact gtgtcgaaag catgagtgat ggtacagctt ctgcccgatc atccagccca
      241 cttgacaggg atcctgcctt tcgggtgatt acagttacta aggaaacagg tctaggtctg
      301 aagatcctag gcggaattaa caggaatgaa ggaccgctgg tgtatattca cgaagtcatt
      361 cctggaggtg actgttacaa ggatggacgt ttgaagccag gagatcaact tgtctcaata
      421 aacaaggaat ctatgattgg tgtatcattt gaagaagcaa aaagcataat taccagagcc
      481 aagttgaggt cagaatctcc ctgggagata gcattcatca gacaaaagtc ttactgtggc
      541 catccaggaa atatttgctg tccatcccca caagtgtcag aagactgtgg acctcaaacc
      601 tcaacattta ctcttctttc ctctccctct gaaacactac ttccaaagac ttcatccact
      661 ccccagactc aggactccac tttcccttct tgtaaagcaa ttcagacaaa acctgaacac
      721 gataaaacag aacatagtcc aattacttct ttggacaaca gccctgcaga tacatctaat
      781 gcagacattg ctccagcctg gactgatgat gattctggac cacaaggaaa gatttcccta
      841 aatccttctg ttcgccttaa ggcagagaaa ctggaaatgg ctctcaatta cctcggtata
      901 cagccaacaa aggaacaacg tgaagccctg agagagcaag tccaggccga ctcaaagggg
      961 actgtgtctt ttggagattt cgtccaggtt gccagaagtt tgttttgctt gcagttggat
     1021 gaagtaaatg ttggtgtcca tgaaatcccc agcatcttag actcacagct tctcccctgt
     1081 gattctctag aagcagatga agtgggaaaa cttagacaag aaagaaacgc tgctctagag
     1141 gaacggaatg tgcttaagga gaagttactg gaatcagaaa agcacaggaa acaattgata
     1201 gaagaactcc agaatgtgaa gcaggaagcc aaagctgtag ctgaggaaac ccgagctctg
     1261 cgaagccgga ttcatctcgc agaagctgca cagcggcagg cacacgggat ggaaatggat
     1321 tatgaagagg tgatccgtct gctagaggct gaggtctcag aactaaaggc tcagctcgct
     1381 gattattctg accaaaataa agaaagtgtc caggacttga gaaaaagagt caccgttctt
     1441 gactgccaat tgcgaaaatc agaaatggct cggaaagcat tcaaggcgtc cactgaaagg
     1501 ctccttggtt tcatagaggc tattcaagaa gttcttttgg atagttctgc tcctttatca
     1561 actttaagtg aaagaagagc tgtgctcgca tctcagactt cgcttccact gctggcaagg
     1621 aacggacgca gcttcccagc aaccctgctt ctggaatcca aggagcttgt cagatctgtc
     1681 cgtgccatac ttgatatgga ctgcttacct tacgggtggg aggaagctta cacagcagat
     1741 ggaatcaagt acttcatcaa ccacgtgaca cagaccacgt cctggatcca ccccgtgatg
     1801 agcgccctga acctgtcctg tgcagaggag agtgaagagg actgtcccag agagctaaca
     1861 gacccgaaaa gctgatgggt ttccatggga aatggagcag cagagtcctc tggcttctca
     1921 gtccatgtcc acaaccagac acaagccacc acaccccgag acacaggaat ccagcacgtg
     1981 caccaggcag ggtgtcaagt cgcaagtgtg gtattttcgt gtacatgtta aagatcagtt
     2041 gccactacag tagttttttt ggaaataatc tagttgcatt tattgaagtc atttatagtc
     2101 agattttaca tgcataaacc tctttataat tagatcttta taactcagta tgttagctca
     2161 ttgtttggta tgagatacaa tggtttgtat atcaacactt catattgaaa agttatacga
     2221 acatagcaaa ctccttttta taactctccc tcccaaccca cagcttagga aaaatgttct
     2281 gagaaagcga ggggaggctg cctcacagct gtcccactag ctgctgacta caacttgtac
     2341 caaataggac accacctaac ttatattatt aggagacatc tatcatttat aaagtgcttt
     2401 caagccgggc agtggtggtg cacgccttta atcccagcac ttgggaggta gaggcaggcg
     2461 gatttctgag ttcgaggcca gcctggccta caaagtgagt tccaggacag ccagggctac
     2521 acagagaaac cctgtctcga aaaaaaaaaa aaaaaaaatg ctttcaaacc tcaccttact
     2581 taaaccaaac agcatagatt ttgagctgat ctacagggca gttctactca tggcttcagc
     2641 tggagaaaca gtggttcaga gagacagagc agcccatccc agggatgaga ctcacacctt
     2701 atcttctgat tccgtgtcca ggcgcctttg ccctgctccc tactgtcccc acagagggag
     2761 attgcagccc agcagagtat ctacagtctg ttgatgcagc tgggtccaca gctgtgcatt
     2821 ccacagcagt ccagaggaca cctcagagtc atgacccact ctcttccttc tgcggcccca
     2881 accccaccac caccaccacc accaccaccc ttagatacca agcaggacac tgctctgtga
     2941 cttttcagtg ggctttgtat tttctagact agagacactg gctcatggcc atgcttaggt
     3001 gccatgagcc agtaggagca tctaaagaga gctgacagga gaaaggtatt tgtttaaaca
     3061 ctgctggagc gcttgtaaaa ggatggaggc caggagccaa gcaaagcagc gcagcatcac
     3121 ttaggcaagc atagagctcc caagaacacg gtgcaagaac cttcactcag ggccacttta
     3181 taagtaagtc acggagttcc tgcagtggag cagcacctgt gtcagcatca gaccctagct
     3241 ccttacattc tctgctgagt tttacctggt atagggaatg catatggaaa atacacatgg
     3301 gcatcgtgct cacccatacc tctctgaata catttaagat gtagggttta agctgaatgc
     3361 acttaggatt catgttttcc ttcatgagga agaacataaa gtcaaataca gactgacaag
     3421 gagactcgaa ccctaacaac gacagaatgg ctggagcaaa cgtatgcctc tcctcacagc
     3481 tgtctggatc ttaggatgct tcgagaagcg gggtaggggt aggtggcttt gagagcagct
     3541 gcagaaggac ctgtttcaag tcccaaagag gtgtgaacag gcactcacac gcttttataa
     3601 gaccgtctct gctgtgacac cagcacactc ctgttaggag atcattctcc tgcctcgcat
     3661 tggagagtgt cctcaattgt ttgtaaggga agctgagatg ggctcctgaa gcatgcagtc
     3721 tttaatctgt atgtgtgcat gtgtgtgtgg cactcacaac ctctctgctg ctagtatcaa
     3781 gtccctccct atttctacca aatacataat caaaaagatc tataaaaaca catagctcta
     3841 tgtactgagc actctatacc atacatttcg gtatacaatg aacatctttt gggaggtctt
     3901 tttgggatag ccactctctg tgtataccac cctggccttg agttcacaat ccccctgcct
     3961 caacctccca agtactggta tttcagcaac aagtaccttc ttgaaggtac ccaaagtgat
     4021 tccaatttta tgaaaaagct gaggtttaga aagaagtggt cccaaggatc ccaccatgcc
     4081 tttgtgttga tgctggatct gaggcaagtc ttagacccca gggcttcctt aaaccagggt
     4141 gtagagcctc ctggatttag tcagccctgc aggactccag ctttcagtca cgaagaactt
     4201 cccgatttgt aagaaaggaa ttctccagga gaaaatagca ttccatcagg ttcctgtgta
     4261 actgagcatc tcatgtgaat gcagctaagg aggttgagcc tctgaattag ctgaatcagg
     4321 cgaacactca ttgagaacta ttctttagtc cctatgtcct cacccatgtg ttcccttggg
     4381 atgctcagta gctaccagcg gtgtgaccag cactctggtc accagggcaa agcagagcta
     4441 cagctaacca tttcaaaata aaaatgatct tgaaagtcag aatttgttaa cttctaaatt
     4501 ttaaaaatag tttcttttcc tttcaaaaac gagatcaaag ttctgtagaa ataagtcgag
     4561 ttagataaat agcccgtcta actttctgga agctgccgtc accaatattt cagtaactat
     4621 ttcccctcga gggtaagcct gccaccctta aacagctccc ccttgaattg gtatgttgtg
     4681 gtcatctttt catggtgata tacgcattct gttgcatttt aagtgtctgc ttaagctatc
     4741 acttcccaga atacccttca ccagttgttc agcaactcat taaagaaatc ttaggctact
     4801 gtaaggtctt tcccgtaaca gtgtcatggc gagcatttgt gtatttatta aaaccttttc
     4861 ttcaagtacc cccgcactca aacatgagcg tctgtagact gaatactttt gaaagccact
     4921 gtgtcagagt acaaagtttt gtcactgaac aaagagcttc tccatccctg cctaaaaaac
     4981 ctggattttt gttttaaatt ggatattttc tttatttaca tttcaaatgt aaacctggat
     5041 gttttaatca ttgggtttta tcatctcttt agcatcggag actggcttgc tgtgtggggc
     5101 agagtctggc agtgactaat tcagtgttcc acacatggca ttcctctcag tgtgttctac
     5161 tttacatgta atgatgataa ggacttgctt ctaaattagc agagagagca aaggcatgca
     5221 tacagcatgc gcaccatttc tctatctgtg gaacagtggc atacgtccct gtgcccacac
     5281 aaggcaactc agcatgcatc acctgagcac ctactaagtg cctgaccatg caaagtatta
     5341 gaattgtgga cagtacaaac ttcaaagtca aagagctcaa tgtcttaata tttctgtaca
     5401 cacacacaca cacacacaca cacactcaaa caccaacaat tggtattctg tacaggataa
     5461 gaagttaagg atttgtttcc taagaacccc ttaaatttga ataattatgg aaaatattga
     5521 cccccacaca cacaccttgg ctagaaacgg agaagaagga acgtgctgga agaagaggct
     5581 ctccaataac aaatgaaagg cagctgtcaa aatagactca aacagcacac tcataaactg
     5641 cttgcgcaat cagaaaatat tatccttttt ctagggagaa ataggacatt tctctacggt
     5701 aagcaaaatg taactttttg aagggtcaac actcttgaca tttttatgat actcatacag
     5761 acagaactga acaaacatta atacagcttt cacagtcttg ggtatgattt tcaagatgat
     5821 gaaaaagcac agactatgcc tgtggaactt aaaggattaa acggaatgcg cctgtggatc
     5881 atgactttag aaatgtaaaa ctcgagatgt tctagccata gctgttcacg tgtaatatca
     5941 tgtatcagta aaatgattta taaatgattt tataaatact aaa
//
