LOCUS       NM_001358563            2226 bp    mRNA    linear   ROD 08-FEB-2024
DEFINITION  Mus musculus syntaxin 7 (Stx7), transcript variant 2, mRNA.
ACCESSION   NM_001358563 XM_006512800
VERSION     NM_001358563.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2226)
  AUTHORS   Wu,J., Zhang,H., Yang,L., Chen,Y., Li,J., Yang,M., Zhang,X., He,C.,
            Wang,X. and Xu,X.
  TITLE     Syntaxin 7 modulates seizure activity in epilepsy
  JOURNAL   Neurobiol Dis 181, 106118 (2023)
   PUBMED   37031804
  REMARK    GeneRIF: Syntaxin 7 modulates seizure activity in epilepsy.
REFERENCE   2  (bases 1 to 2226)
  AUTHORS   Sun-Wada,G.H., Tabata,H. and Wada,Y.
  TITLE     Vacuolar-type proton ATPase is required for maintenance of
            apicobasal polarity of embryonic visceral endoderm
  JOURNAL   Sci Rep 11 (1), 19355 (2021)
   PUBMED   34588579
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2226)
  AUTHORS   Mori,Y., Takenaka,K.I., Fukazawa,Y. and Takamori,S.
  TITLE     The endosomal Q-SNARE, Syntaxin 7, defines a rapidly replenishing
            synaptic vesicle recycling pool in hippocampal neurons
  JOURNAL   Commun Biol 4 (1), 981 (2021)
   PUBMED   34408265
  REMARK    GeneRIF: The endosomal Q-SNARE, Syntaxin 7, defines a rapidly
            replenishing synaptic vesicle recycling pool in hippocampal
            neurons.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2226)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2226)
  AUTHORS   Castonguay,J., Orth,J.H.C., Muller,T., Sleman,F., Grimm,C.,
            Wahl-Schott,C., Biel,M., Mallmann,R.T., Bildl,W., Schulte,U. and
            Klugbauer,N.
  TITLE     The two-pore channel TPC1 is required for efficient protein
            processing through early and recycling endosomes
  JOURNAL   Sci Rep 7 (1), 10038 (2017)
   PUBMED   28855648
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2226)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
REFERENCE   7  (bases 1 to 2226)
  AUTHORS   Wade,N., Bryant,N.J., Connolly,L.M., Simpson,R.J., Luzio,J.P.,
            Piper,R.C. and James,D.E.
  TITLE     Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin
            6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16
            melanoma cells
  JOURNAL   J Biol Chem 276 (23), 19820-19827 (2001)
   PUBMED   11278762
REFERENCE   8  (bases 1 to 2226)
  AUTHORS   Mullock,B.M., Smith,C.W., Ihrke,G., Bright,N.A., Lindsay,M.,
            Parkinson,E.J., Brooks,D.A., Parton,R.G., James,D.E., Luzio,J.P.
            and Piper,R.C.
  TITLE     Syntaxin 7 is localized to late endosome compartments, associates
            with Vamp 8, and Is required for late endosome-lysosome fusion
  JOURNAL   Mol Biol Cell 11 (9), 3137-3153 (2000)
   PUBMED   10982406
REFERENCE   9  (bases 1 to 2226)
  AUTHORS   Hirling,H., Steiner,P., Chaperon,C., Marsault,R., Regazzi,R. and
            Catsicas,S.
  TITLE     Syntaxin 13 is a developmentally regulated SNARE involved in
            neurite outgrowth and endosomal trafficking
  JOURNAL   Eur J Neurosci 12 (6), 1913-1923 (2000)
   PUBMED   10886332
REFERENCE   10 (bases 1 to 2226)
  AUTHORS   Nakamura,N., Yamamoto,A., Wada,Y. and Futai,M.
  TITLE     Syntaxin 7 mediates endocytic trafficking to late endosomes
  JOURNAL   J Biol Chem 275 (9), 6523-6529 (2000)
   PUBMED   10692457
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125010.6, BY732316.1, AB019212.1, AK158923.1 and BY618650.1.
            
            [WARNING] On Apr 1, 2024 this sequence was replaced by
            NM_001358563.2.
            
            On Dec 1, 2017 this sequence version replaced XM_006512800.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK142742.1, AK082927.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                AC125010.6         159693-159705       c
            14-40               BY732316.1         2-28
            41-273              AB019212.1         1-233
            274-2210            AK158923.1         565-2501
            2211-2226           BY618650.1         364-379
FEATURES             Location/Qualifiers
     source          1..2226
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 11.45 cM"
     gene            1..2226
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /note="syntaxin 7"
                     /db_xref="GeneID:53331"
                     /db_xref="MGI:MGI:1858210"
     exon            1..120
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            121..270
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..971
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /codon_start=1
                     /product="syntaxin-7"
                     /protein_id="NP_001345492.1"
                     /db_xref="CCDS:CCDS23749.1"
                     /db_xref="GeneID:53331"
                     /db_xref="MGI:MGI:1858210"
                     /translation="MSYTPGIGGDSAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQD
                     SPELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLT
                     NFQKAQRQAAEREKEFVARVRASSRVSGGFPEDSSKEKNLVSWESQTQPQVQVQDEEI
                     TEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHEQGDMIDSIEANVESAEVHVQ
                     QANQQLSRAADYQRKSRKTLCIIIFILVVGIVIICLIVWGLKG"
     exon            271..340
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            341..434
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            435..572
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            573..625
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            626..722
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            723..795
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            796..878
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
     exon            879..2212
                     /gene="Stx7"
                     /gene_synonym="Syn7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgagcatg cgcagtgggc gtgcttgtgc cgccgcccat cagctgagac cggctgcgcc
       61 aggcagtggg cccccgggtg acagcggctg gaggtggccg aggaagccgg cgaggtcagg
      121 gtgactccta gaaatccaca tagcctacct gcatctgatg aaatcagcca gccagccaac
      181 cagccatgtc ttacactccg gggattggtg gggactctgc gcagctagca caacgcatct
      241 cctctaacat ccaaaagatc acacaatgct ccgtggaaat acaaaggact ctgaatcaac
      301 ttggaacacc tcaagactca ccggaactga ggcaacagct gcagcagaag cagcagtata
      361 ctaaccaact tgcgaaagaa accgataagt acattaaaga gtttggctct ctgcccacca
      421 cccccagtga gcagcgtcag agaaagatac agaaagaccg attagtggca gagttcacca
      481 catcgctgac aaacttccag aaggcccaga ggcaggctgc tgagagagag aaagagttcg
      541 ttgctcgagt gcgagccagc tccagggtat cgggtggttt tcctgaagac agctcaaaag
      601 aaaagaatct tgtatcctgg gaaagccaaa cacagcctca agtgcaggtc caagatgaag
      661 aaatcacaga ggatgacctc cgactcattc atgagagaga gtcttcaatc aggcagctgg
      721 aagctgatat tatggacatt aatgaaatat ttaaagactt ggggatgatg attcatgaac
      781 aaggcgatat gattgacagc atagaagcca atgtagaaag tgcggaagtt cacgttcaac
      841 aggcaaacca gcagctgtca agagcggcag actatcagcg caaatccagg aaaactctct
      901 gcattatcat ttttatcctc gtggtcggaa tcgtgatcat ctgtctcatc gtatggggac
      961 tgaaaggctg agccccgagg gcgtggacga ctgcatgatg ctgtctgagc gatgcaggca
     1021 gattcttgcg atcactttct cttatcgtta tcttgaggct gttgtgtaaa atgatggttc
     1081 catactttgc catttttact agggtggggg gattcttttt ggattcagtc tgatattttc
     1141 taatacccaa ggcttttcta aacaccctta ctggcacagc ttccctgctt tttagttcaa
     1201 caactgttag gttttgctca cgttgtatat gcctttcatt tgtaatttat ttattgtaac
     1261 tttttgactg agttttggga attatttgat tggcgtgtat actctgcctg cacctctgta
     1321 actgtgtaac atgtgtaaca tgattgcatt atcttattta aaaagaaagc ccaagtttaa
     1381 atttcatttg tccagtaaat gttctcaata ggaaaccctt aacataactg tttgtgggat
     1441 gttttatccg ctgtggtcca cagcagtgca gatcgttatt gctctttcat tattggattg
     1501 ttgttttcgt ctctgaataa aatcagtgaa tcttttcctg atgtgtatgt atatatgcat
     1561 ttgctgtgga ttacctagta aagacagtaa ggataggttg tttttaacat tatggactgt
     1621 ttaatccaat gcatactaaa gaaagcttag ttactgtatt gttcagtgaa agttggagga
     1681 agtggctgaa aggtccatac ctgcatctat tctgttcaga tgctaaagat tccagtctct
     1741 tactgcactg aaccactttc accatatggt ctggctttgt ggccattata ccttccctcg
     1801 tgcgccatgg aacacttctt aggcctgtat ctttgggtcc tgtcttcaca aagtaatgtt
     1861 cccatagtta cagatttggg atttcatttt atatttagtt tttgacactt aagttttaga
     1921 gtttatttag atgccatttt tttattattc ttcattcaaa taggaatcag acgtctgcca
     1981 atgaacacac ttgtcttttt tgaatcaatg ttttaatgca ctaatatgaa tgctgtaaga
     2041 ggggttatct tagtttatca tttgtgtttt ataatgttct tacacagcag tttgctaatg
     2101 atggcactgt ttaatgtggc tctgaaacct ttaaatggga acaagtgaaa tattaacaaa
     2161 ataattgtat ctttgcaagc agaataaaga tgattctgga gatgtctgct aaaaaaaaaa
     2221 aaaaaa
//
