LOCUS       NM_133789               3562 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Mus musculus striatin, calmodulin binding protein 4 (Strn4),
            transcript variant 1, mRNA.
ACCESSION   NM_133789
VERSION     NM_133789.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3562)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3562)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 3562)
  AUTHORS   Chen,Y.K., Chen,C.Y., Hu,H.T. and Hsueh,Y.P.
  TITLE     CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and
            synaptic distribution of the striatin-PP2A complex
  JOURNAL   Mol Biol Cell 23 (22), 4383-4392 (2012)
   PUBMED   23015759
REFERENCE   4  (bases 1 to 3562)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   5  (bases 1 to 3562)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   6  (bases 1 to 3562)
  AUTHORS   Castets,F., Rakitina,T., Gaillard,S., Moqrich,A., Mattei,M.G. and
            Monneron,A.
  TITLE     Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat
            proteins principally expressed in the brain
  JOURNAL   J Biol Chem 275 (26), 19970-19977 (2000)
   PUBMED   10748158
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC148981.7, BC080283.1 and BC066805.1.
            
            On Jun 18, 2009 this sequence version replaced NM_133789.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF414080.1, BC080283.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            NMD candidate          :: translation inferred from conservation
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-489               AC148981.7         95132-95620         c
            490-3533            BC080283.1         56-3099
            3534-3562           BC066805.1         4109-4137
FEATURES             Location/Qualifiers
     source          1..3562
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.15 cM"
     gene            1..3562
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /note="striatin, calmodulin binding protein 4"
                     /db_xref="GeneID:97387"
                     /db_xref="MGI:MGI:2142346"
     exon            1..746
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     CDS             465..2747
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /note="isoform 1 is encoded by transcript variant 1;
                     striatin-4"
                     /codon_start=1
                     /product="striatin-4 isoform 1"
                     /protein_id="NP_598550.2"
                     /db_xref="CCDS:CCDS39786.1"
                     /db_xref="GeneID:97387"
                     /db_xref="MGI:MGI:2142346"
                     /translation="MMEERAAAAVASAASSCRPLGSGTAPNPTAAAPASSPAPGPGPV
                     GKGGGGGGSPGPTAGPEPLSLPGILHFIQHEWARFEAEKARWEAERAELQAQVAFLQG
                     ERKGQENLKTDLVRRIKMLEYALKQERAKYHKLKFGTDLNQGEKKTDLSEQVSNGPVE
                     SVTLENSPLVWKEGRQLLRQYLEEVGYTDTILDMRSKRVRSLLGRSLELNGAGEPVEG
                     APRASPGPGGLSGGESLLVKQIEEQIKRNAAGKDGKERLGGSVLEQIPFLQNCEDEDS
                     DEDDELDSVQHKKQRVRLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGEGSPDP
                     RRCTSEGNPHELESRRVKLQGILADLRDVDGLPPKVTVPPPGTPQPRPHEGSFGFSSD
                     VFIMDTIGGGEVSLGDLADLTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRS
                     LAFHHSQSALLTASEDGTLKLWNLQKAVTAKKNAALDVEPIHAFRAHRGPVLAVTMGS
                     NSEYCYSGGADARIHSWKIPDLNMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTSQRL
                     ASCSADGTVRIWDPSSSGPSCLCTFPMDGEHGIPTSVAFTSTEPAHVVASFRSGDTVL
                     YDLEAGSALLTLESRGSSGPAQINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSM
                     VAHLDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEITAHRKKHEEAIHAVAC
                     HPSKALIASAGADALAKVFV"
     exon            747..850
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            851..924
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            925..1003
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1004..1201
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..1343
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1503
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1617
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1618..1733
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1734..1909
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1910..1957
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            1958..2079
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2250
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            2251..2391
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            2392..2490
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            2491..2577
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            2578..2809
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     exon            2810..3535
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3515..3520
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /note="hexamer: AATAAA"
     polyA_site      3533
                     /gene="Strn4"
                     /gene_synonym="ZIN; zinedin"
                     /note="major polyA site"
ORIGIN      
        1 ttggataggg ttattatgac aaccgacttc ctctggtcag agcccactcc ccaccccagg
       61 tcgtcttttt tgttttttgt tttttttttc ttcactaagt gaaagagatg ggggtgtatt
      121 tgcatttgga ggggatagga ctctgacatt ggggagaatg cagaaaaaaa agtccggtct
      181 ggtctctcga ccgcaaagga gacaattgcg agggaccctg ggtcctttgc ctacgtagag
      241 gcagtccctc cccctccctg tcagcacccc cgcccgcgcg caccaccggg gtcgacccgg
      301 gtgggtgggc gaggctcgcg cccagccccg tgcttgtccc cgctcccctc gcccgcccag
      361 cgcgcgcgcg cgcgcacacg aggcgggggt gtagaagtgt gaagctgcgc gtccgcgcag
      421 gcgcgcgagg tacagcgggc gcgcgggccg gccccggggc ctccatgatg gaggagcgag
      481 cggccgccgc ggtcgcatcg gccgcctcct cctgccgccc tctgggctcg ggcacggctc
      541 ccaacccgac ggcggcggcc ccggcctcca gccctgctcc tgggcccggc ccggtaggaa
      601 aaggaggtgg cggcggaggc agcccgggcc ctacggcggg cccggagccc ctcagcctgc
      661 cggggatcct gcactttatc caacacgagt gggcacgctt cgaagccgag aaggcccgct
      721 gggaggccga gcgcgccgag ctgcaggctc aggtggcttt cctccagggg gagaggaaag
      781 gccaagagaa tctaaagacg gacctggtgc ggcggatcaa gatgctggag tatgcactaa
      841 agcaggagag ggccaaatat cataaactga agtttggtac agacctgaat cagggggaga
      901 agaagacaga tctgtcagaa caagtctcca atggccctgt agagtcggtc acactggaga
      961 acagcccatt ggtgtggaag gagggtcgac agcttctgcg acagtacctg gaagaggtgg
     1021 gctacacaga taccatcttg gacatgcggt ccaagcgtgt gcgttccctt ctgggccgtt
     1081 cactggaact caatggggcc ggtgagcccg ttgagggggc ccccagggct tcaccaggcc
     1141 ctgggggact tagcggtggc gagtctctac tggtaaaaca gatcgaggaa cagatcaaga
     1201 ggaatgcagc tggcaaagat ggcaaggagc gcctgggtgg ctcggtgctg gagcagatac
     1261 ccttcctgca gaactgcgag gatgaagaca gcgatgagga tgatgaactg gacagtgtgc
     1321 agcataagaa gcaacgtgtg aggctcccat ccaaggccct agtgcctgaa atggaggacg
     1381 aggatgaaga ggatgactca gaagatgcca tcaatgagtt tgatttcctg ggctcaggag
     1441 aggatggaga ggggtctcca gatcctcgac gttgtacttc agaggggaac ccccatgagc
     1501 tggaaagccg tcgggtcaaa ctccagggaa ttcttgctga cctccgggat gtggatgggc
     1561 tgcccccgaa agtgactgtc ccacctcctg gcacacccca gccccggcct catgaaggtt
     1621 cctttggctt ctcctcagac gtcttcatca tggacactat cgggggcggg gaggtgagcc
     1681 tgggggactt ggcagatctc accgtcacca atgacaacga cctcagctgt gatctgtctg
     1741 acagcaaaga cgctttcaag aagacatgga accccaagtt taccctccgc tcacactacg
     1801 atggcatccg ctccctggcc ttccaccaca gccagtcagc actgcttact gcctctgagg
     1861 atggcacact caaactgtgg aacctgcaga aggcagttac ggccaagaaa aatgctgcac
     1921 tggatgtgga gccgattcat gctttccgag ctcacagggg cccggtgctg gcagtcacca
     1981 tgggcagcaa cagcgagtac tgttacagtg gtggggctga tgccaggatc cacagctgga
     2041 agattcctga cctcaacatg gacccatatg atggctatga cccaagtgtg ctgagccatg
     2101 tcctggaagg ccatggggat gctgtgtggg gtctggcctt cagtcccacc tcccagcgcc
     2161 tagcatcctg ctctgccgat ggcaccgtcc gcatctggga tcccagcagc agtggtccaa
     2221 gctgcctctg taccttcccc atggatggag aacatggaat tcccacctca gtggccttca
     2281 ccagcactga acctgcccat gtcgtggcct cctttcgttc tggtgatacc gttctttatg
     2341 acctggaagc tggcagcgcc cttctcacat tggagtctcg agggagcagt ggcccagcac
     2401 agatcaacca ggtggtgagt cacccaagcc agcctctcac catcactgca cacgacgaca
     2461 ggggcatccg gttcctggac aatcgaacag gtaaatctgt gcattccatg gtggcccacc
     2521 tggatgcagt cacctgccta gctgtggacc caaatggcgt gttcttgatg tcaggaagcc
     2581 acgactgttc tctgcgttta tggagcctag acaacaagac atgtgtgcag gagatcacgg
     2641 cccaccgcaa gaagcatgag gaggccatcc atgcagtggc ctgccatccc agcaaggcac
     2701 ttattgccag tgctggtgct gatgccctag ccaaggtctt cgtatgatcc cacctggcct
     2761 cgccctggct gcacagtgtc agggagcggg gccaggcagt ggggctgagg cagcccccag
     2821 cctcaccttc agaggctctg agtcttggcc tctttcatct tcctggagcc tggtggtgct
     2881 aaaggccctt tccccaggag tcacccctca aggatggcct ctggggtttc tgctcatgcc
     2941 ccaaccccaa ctcctgacat agctgtcgtc ctgagtttga cacagcccag gctgggtgtc
     3001 ctttgggatc tgattttgac caagatgaaa gaagatgcca ggctccctcc tagagtgcca
     3061 ccctccctca ttcatcagat gaagggctgt gcagagaggg gtctcctggg gccctcctat
     3121 gtgggcccca ggttgtcctt ttggacctca gtccattcct cttgcttccc aacactaacc
     3181 aagcctctgg ggccaggcct tcctgggaag ggcctccact cctctggggc attgtcctag
     3241 ccacaggccc tccttgagat gtagagagag ggtggagtgg gccctgtgcc cctagttctc
     3301 tgtatatctg tataaaggaa tgggatttta atggcaccca ccccacgtta tcactgtgtg
     3361 atagtctgtc agtctcctcc ttgctccaca ctttggcctc tatttatttc actctttatt
     3421 tgggtcccac cttatgccct cggttcccct ttcaggttcc tgttcataag ccccttcctt
     3481 tttgccccaa cttgtatgtg aaaaaaattg tctcaataaa ccctttggag taagaaaaaa
     3541 aaaaaaaaaa aaaaaaaaaa aa
//
