LOCUS       NM_001379315           16502 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus spermatid perinuclear RNA binding protein (Strbp),
            transcript variant 5, mRNA.
ACCESSION   NM_001379315 XM_011239046
VERSION     NM_001379315.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 16502)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 16502)
  AUTHORS   Lau,N.C., Seto,A.G., Kim,J., Kuramochi-Miyagawa,S., Nakano,T.,
            Bartel,D.P. and Kingston,R.E.
  TITLE     Characterization of the piRNA complex from rat testes
  JOURNAL   Science 313 (5785), 363-367 (2006)
   PUBMED   16778019
REFERENCE   3  (bases 1 to 16502)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 16502)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 16502)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 16502)
  AUTHORS   Pires-daSilva,A., Nayernia,K., Engel,W., Torres,M., Stoykova,A.,
            Chowdhury,K. and Gruss,P.
  TITLE     Mice deficient for spermatid perinuclear RNA-binding protein show
            neurologic, spermatogenic, and sperm morphological abnormalities
  JOURNAL   Dev Biol 233 (2), 319-328 (2001)
   PUBMED   11336498
REFERENCE   7  (bases 1 to 16502)
  AUTHORS   Schumacher,J.M., Artzt,K. and Braun,R.E.
  TITLE     Spermatid perinuclear ribonucleic acid-binding protein binds
            microtubules in vitro and associates with abnormal manchettes in
            vivo in mice
  JOURNAL   Biol Reprod 59 (1), 69-76 (1998)
   PUBMED   9674995
REFERENCE   8  (bases 1 to 16502)
  AUTHORS   Stoykova,A., Chowdhury,K., Bonaldo,P., Torres,M. and Gruss,P.
  TITLE     Gene trap expression and mutational analysis for genes involved in
            the development of the mammalian nervous system
  JOURNAL   Dev Dyn 212 (2), 198-213 (1998)
   PUBMED   9626495
REFERENCE   9  (bases 1 to 16502)
  AUTHORS   Schumacher,J.M., Lee,K., Edelhoff,S. and Braun,R.E.
  TITLE     Spnr, a murine RNA-binding protein that is localized to cytoplasmic
            microtubules
  JOURNAL   J Cell Biol 129 (4), 1023-1032 (1995)
   PUBMED   7744952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL805959.11, BX545905.9 and AL953890.7.
            
            On Mar 30, 2020 this sequence version replaced XM_011239046.3.
            
            Transcript Variant: This variant (5), as well as variants 1, 2, and
            4, encodes isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363658.2308351.1,
                                           SRR7974084.27450.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-154               AL805959.11        6230-6383           c
            155-324             BX545905.9         76728-76897         c
            325-545             BX545905.9         75083-75303         c
            546-711             BX545905.9         70463-70628         c
            712-856             BX545905.9         65036-65180         c
            857-948             BX545905.9         57047-57138         c
            949-1044            BX545905.9         56094-56189         c
            1045-1156           BX545905.9         54790-54901         c
            1157-1254           BX545905.9         54105-54202         c
            1255-1366           BX545905.9         53785-53896         c
            1367-1459           BX545905.9         33534-33626         c
            1460-1659           BX545905.9         32547-32746         c
            1660-1818           BX545905.9         30357-30515         c
            1819-1953           BX545905.9         28733-28867         c
            1954-2094           BX545905.9         26316-26456         c
            2095-2218           BX545905.9         20269-20392         c
            2219-2263           BX545905.9         16122-16166         c
            2264-13981          BX545905.9         2001-13718          c
            13982-16502         AL953890.7         155202-157722       c
FEATURES             Location/Qualifiers
     source          1..16502
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 24.19 cM"
     gene            1..16502
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /note="spermatid perinuclear RNA binding protein"
                     /db_xref="GeneID:20744"
                     /db_xref="MGI:MGI:104626"
     exon            1..154
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            155..324
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            325..545
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            546..711
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            712..856
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            857..948
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1044
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1156
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1254
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1366
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1459
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1659
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1818
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1819..1953
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            1954..2094
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            2095..2218
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2263
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     exon            2264..16502
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2880..2885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /note="hexamer: AATAAA"
     polyA_site      2898
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
     regulatory      3196..3201
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /note="hexamer: AATAAA"
     polyA_site      3214
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /note="major polyA site"
     regulatory      16479..16484
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /note="hexamer: AATAAA"
     polyA_site      16502
                     /gene="Strbp"
                     /gene_synonym="6430510M02Rik; C230082I21Rik; Spnr"
                     /note="major polyA site"
ORIGIN      
        1 gccgaagccg agctcggatc cgcgagcgcc accaaggcag cagccgccgc agccgccgcc
       61 gctgtgctga ggagccggag acgcgggcgg acgaggtggc ggcggcggcg gagcgggagc
      121 ggggagcgga cgcgggcgga gcgcggcggc gcgggtgtat tccagagaac aattttgaga
      181 tatctttgct tatatttgac attgagcagt caggggattt aggcatatga ggaggtactg
      241 tcacataaaa cagtgtctag tgaagacgac aagaaagaga gaaaaggatc ggaaaaagaa
      301 gctaaaatac cataggaaac catgagatct attagatctt ttgccaatga tgatcgccat
      361 gttatggtga aacattcaac aatctatcca tctccagagg aacttgaagc tgtgcaaaat
      421 atggtgtcta ctgttgaatg tgctcttaaa catgtctcag attggctgga cgaaacaaac
      481 aaaggcacaa aacctgaggg ggaaacagaa gtaaagaaag atgaagctgt ggaaaactat
      541 tccaaggatc aaggtggccg gacattgtgt ggtgtaatga ggattggctt ggttgcaaaa
      601 ggcttgctga ttaaagatga tatggacctg gagctagtct taatgtgcaa agacaaaccc
      661 acggaaaccc tgttaaatac agttaaagat aaccttccta ttcagattca gaaactaaca
      721 gaagagaaat accaagtgga acaatgtata aatgaagcat ccattataat tcggaacacg
      781 aaagagccaa cactgacttt gaaggtgata cttacttccc ctctaattag ggacgaattg
      841 gagaagaagg atggagaaaa tgttatgatg aaagaccctc cggacttatt ggacaggcaa
      901 aaatgcctga atgccttggc ttctcttcga catgccaaat ggttccaggc aagggcaaat
      961 ggattaaaat catgtgtaat tgtcctccgc attctgcgtg atttgtgcaa cagagtaccc
     1021 acatgggcac cattgaaagg atggccacta gagcttatat gtgaaaagtc tataggtact
     1081 tgtaatagac ctttgggcgc tggggaggcc ttgagacgag taatggagtg tttggcatct
     1141 ggaatactac ttcctggtgg ccctggtctt catgatcctt gtgagcgaga cccaacagat
     1201 gctctaagct atatgaccac tcagcaaaaa gaagatatta cccatagtgc acagcatgca
     1261 cttagactat cagcctttgg ccagatttat aaagtgctgg agatggaccc tcttccgtct
     1321 agtaagcctt ttcagaagta ttcctggtca gttactgata aagaaggtgc tgggtcttca
     1381 gctctaaaga ggccatttga agatggattg ggggatgata aagatcccaa caagaagatg
     1441 aaacgaaact taaggaaaat tctagatagt aaagcaatag accttatgaa tgcactaatg
     1501 agattaaatc agatcaggcc cgggcttcag tataagcttt tgtcacaatc tggcccggtc
     1561 catgccccag tcttcacaat gtctgtagat gtggatggca caacatatga agcctcagga
     1621 ccatccaaga aaacagcaaa gcttcatgtg gcagtgaagg ttttacaggc aatgggatac
     1681 ccaacaggtt ttgatgcaga tattgaatgt atcagttccg atgaaaaatc agataatgaa
     1741 agcaaaaatg atacagtatc ttcaaactca agcaataata ctggaaattc tacaactgag
     1801 acctccagta ccttagaggt aagaactcag ggtcctatcc tcacagcaag tggcaaaaat
     1861 cctgtgatgg agctcaatga aaaaagaaga ggtctcaaat atgaactcat ctcagaaact
     1921 ggtggaagcc atgacaagcg ctttgtaatg gaggtagaag tagatggaca gaaattcaga
     1981 ggtgcaggtc caaacaagaa agtggccaag gcaagtgcag cactagctgc cctggagaag
     2041 ctgttttctg gacccaatgc ggcaaataat aagaaaaaga agatcattcc tcaggcaaaa
     2101 ggtgttgtga atacagcagt atctgcggca gtccaggcag ttcggggcag aggaagagga
     2161 actctgacaa ggggagcatt cgtgggggct acagcagctc ctggatatat agctccaggt
     2221 tacggaaccc catatggtta cagcacagct gcccctgcat atggtttgcc caagagaatg
     2281 gttctgttac ccgttatgaa attcccaaca tatcctgttc cccactactc attcttttag
     2341 taaatgacag aagctcattc ctattgaaca acaatacagt acaatgcaga atgttagaga
     2401 aaaagccttt ttatcctgct ttctttgaac acatacttac ttgatcaaaa ttatttgtaa
     2461 agaacatctt tcctactttt tgattttaac aaatgcaaat tcagttctct aaaacttgaa
     2521 aacaaacaaa agaaaccagt tctgtgaaac ggtacctcat tcctggaaat aatttatacc
     2581 agccccttcg ttgtagggaa gtctagcagc tcaaagttga cgttttaaga gagtatcaga
     2641 ttatgtaaag ttaaatttgt gaaggatgta tagagtctca acactgatta caaataaact
     2701 gctttgttgt aacacagagt actgcctggt tcctgatgca gtcactgatt ggtagctgag
     2761 tgatatgtgc ttactccagg gcacttgaat ttgggctgta gttatttttt ttttaaatac
     2821 agtagaaact tttcatttaa actttaactt tgtaaataac gaagtgtgta attaaagcca
     2881 ataaaatatg ggtttgaata ttgttttatc ttattatttt tgatatgttt tggtatcaaa
     2941 tttcaaggaa ttgaaaacta gtaataactt ggccctagaa acccatttat ttgtaagcaa
     3001 gctgctaaaa caaagcaaag atgatttctc aatctattca ttttgtaagc tctttgtact
     3061 ccatttgtac aagagcatcc ccatgataag gttacattct gttattccag cattgcttat
     3121 taaaatgatg gcaccatcca aagatgggga aggaggattg tgattatttt agtttacgaa
     3181 tttccaagtt aaaaaaataa attaatcaat caccctcttt tgttcttgtg gccttcttca
     3241 ctctgtaaga ctctgtgttc actccttgac tttttccatg tagatagatg attagcaggt
     3301 tttttttttt ttttggaatt ccttgaagag tctcctttcc tcttctttga tatcagaatc
     3361 taaagcagca acaggatccc cataaaaact cgctctctga ttgtcccagt tcttgttgag
     3421 tgctgctgtg aaaagtgaca gatttcagcc atgggtcagc atttactttt aagacacctg
     3481 attatactgg tagaaactgg gagccagtaa cattgtgctg gtctgtgaag ggtgcagacc
     3541 caagtccttc cttgcattct caccatgttt ggaaagctga tgatgttact agaaggtaat
     3601 ggtttcatta aggtactcac ccccattcag gcacaagtgt agtcctctgc agacacaagt
     3661 cactattctt aaaaatgatt taggaagtaa ctacttttct gttaaattcc ttttcaaaac
     3721 ttcaagcagt gcccatcact tgaaagtggt cttactaaac ttaatgtacc aggctccttt
     3781 ggaagggaat gcgagatgag cctgcgggca caaatactgc tcagatgtgt atcacacagt
     3841 catttgttcc tttccttgac ctttgttttc taatagtggt gggtgatact ttaataaaac
     3901 cttgtcactt gctgaaaata gctttaactt gtcattctca tcatgtgtgt tagtggcaag
     3961 acataatgga gcagggccct tttcagctgg gaattttcat gttcattggt ttgttttgct
     4021 gacctatgga tgaaacagag ccatcactga gaagaaaaag catggctgct agtatctagt
     4081 ttttaattaa ttaaatattt acaatggttc tgtttttgaa atactattaa ttggcagttg
     4141 cagttgtatt gttatttgaa attgaccatc aaatttggac tctaggctgg aatctgcctt
     4201 gagatttctc tttagaaaag acttttgcag tctctgactc tgcctcataa ctcaccccct
     4261 ctctgatgga ggaggaagct gtgctgttct ccaacatgat ggccgtcatt tcaaatggtt
     4321 cctaccaagt cttccctctt tcttcttaat tttgttgttt gttggaagtt actaaccatg
     4381 ttgtaaacct gcccagttgc tgcaaacttt tacatttctc tgctttactt aaaacaatgg
     4441 agctgttgac cctatgttag aagtggtaac catgcaagtt caattgttta aattctgtaa
     4501 tgaattaagt gtcctcccac cttttgcccg tcccaccctt cattttgtaa tgaaaattcc
     4561 acttacagtt gaaagagcag agaaatataa atgaagctct tagcttcgtc caattgtatg
     4621 agattaacat aaagttctgc ttctctgctc ttttctccac tgtaggtggt tttttcattg
     4681 acagccccta ttgccagcct ctgagcgtcg caccatttat tattcacttg ggccctcaag
     4741 atttcttctc tgacttctag aaccatcagg ttgtctggct tgaatggcaa ttttatatct
     4801 tggtcttaag agcaatgtga cccctaaggc tttccagctt tcagatccac tctaaccctt
     4861 tttgaaatca atgactaaga attttaaaaa agagcaatac tttgtccaaa gccacgatgt
     4921 ctgttttaaa gctctccttt tggacatgta gcaatatcta gatgtaaacc cttcagtgtg
     4981 tagctcttgt cagggagttt acagaccaat gtagaattta gaatctatgt gagcagtgct
     5041 atatcctctg acacttttta atcgttttta gtacataact tgagctttta cttttctgac
     5101 tttgccagct agcagtatta taattaatcc gagacaggtg tcctccttaa gccatatctt
     5161 ttggtggggg ccgacgcttc accagaggtg tggctggcaa cctgtgcccc ttaaggctgc
     5221 aggagcgcca catctcttgt gcctcataat ggctccatag atttccaaca tacctcatgc
     5281 tgatgaggtt tggtgcatag tatggcaaag taaggggttg ggttaagtag ctcctgagat
     5341 tgtttgtaat ccctcaaact gttaccctct gggaatgaaa tacttaatgg ttttgcttgg
     5401 attagcattt tcttttttct tcttcttctc cttttttttt cttttttttt taaatgggtg
     5461 aatgtttgaa aatcatgaat cagtcaccgt aattaattga agagctggga ataccttgtt
     5521 aatgtatttt taaaactggt gttggaccct ctgtgtattt caggttaata cttttaagca
     5581 gttttcagca cgtttatctc actttattct cgttctcctc ggacctccgt agccatatca
     5641 cttgtataaa ataggctgag atatagtgac tgtaagctgt gatctcagta ttcaaaggta
     5701 agctctttta ttttctgatt aaagaaaaca ataaccaatt aacacaacct gcatatatga
     5761 caatcatatg atgtatttga tctcttaggt cttatgtcac tgcattaact ttaaattttt
     5821 atggtctaaa tgtaaaatag taatttccag catttgtttt aatactcttg taaacgcttt
     5881 atattcaaga gaaacattac acattcactg agtccagtgt atgtgggtag aattgtagga
     5941 tttaatgtat atgtaattta tacataacag aggcacctgc ttgaatataa caattcagtt
     6001 gtaggaacac tatctaagga gagtcaaaat gacagggcac tgtcttgttc aaggagctag
     6061 gatatcagaa tcagtaatgc tggtgacatg ctgtagaatt catgtgcatt tgctgcacag
     6121 gctgagggat acaagtgcca atctcaagaa gatcacctcc tctgacctgt gttgcatgct
     6181 ccaatacagc aacagcaaga agccatttaa aaaagcaata gagaatcaaa gacaaaacta
     6241 taaactgtgg gaaatatatg taattggctg agttaagcta attatttgca gaatcaactt
     6301 cagcaagtta ctgagtctgc agaaaccaaa tctgcttaag gaatcggata atctgtctgt
     6361 ccgtctgact gtctgtctca agttaggaag ctagaatatt atttctcact gtattcagtc
     6421 atgaacagag ttcatttata ggatatcagt attaggccaa accttaatcc acaaatacac
     6481 cttattatgt tagctgttaa gtgctaaagc tgtatgtgtg tgtgtgtatg tataaatgaa
     6541 ttttatgctt tacatttctt tctatagcag tttctgttca tctctagcat taaggctgct
     6601 gaaactttgt tctcacacag aacctgcagt tcatgaggtc ggcttctgtt aaaggctgta
     6661 caaagcagag cagagaagtg cagtgcactg taatcctgtt cctgctgatg ccaggtcctt
     6721 tttctgggac cagggaacag aggctatgat cagtgcaagt atcttaagtt ttctgatgga
     6781 attcctgatg gaattggcct tgttgtaaat aaatacccta ctttggaaga tagtgtatta
     6841 acagtggcaa aagttattaa ttcatttagt agtgtaatta taaaatactg aatatttgta
     6901 ggtttttcaa caccacaaaa ttggtgttac ttgaggattt cctcaagtag catattttct
     6961 ctggcattcg tgatggactg aacttcgctc tggttatgct actcatgttc tgtccaagtg
     7021 ggtgttgaga agatgagaag ctcagcacca ctgcagccct gcttttggca tctctatgta
     7081 tagtcctgca aagaactcaa tgggaaatgt aaaccctgac tacattcttt caatggcagg
     7141 tgaatgttac tgttataaga aatcacttgc tgtaattgtc ctggttttta tttttcacta
     7201 atgataggcg tcgagaagaa gagtcagtac taagtttttc ttcccaagct gtttggagcc
     7261 tgtaaccagg gacattgtaa acagagtgac atgtgaaagc agcctactct gaatggtctg
     7321 cctttcattt ccactctttg aatgccccct caagtcacct agagatagaa agatgccatg
     7381 ttatttagct ttgttctctg caacatctgg tatcatacag ctaggcatca tgattcctta
     7441 gtgtgactag gaggcttgtg gaaggaaatg ggtggagtgt caatgagaac agcaggccca
     7501 agtacctgct gtcatgatga acttcagcac gggtgtgtgt ttctgtacca cctaacttac
     7561 agagcacagt acagctgatt taagatgagt tccccctttt acaaaatagt attttgcaaa
     7621 aagacttttt taagtaaaga attcatgttg ggttaattat ataaataagt atccttttcc
     7681 acataccact atttcagtta ggagctaaca gcttccatta atgtttgaag tttttaaaaa
     7741 tagaattata atataaattt gtcttatgta agatttacag cacagctaga gatacagaat
     7801 agaaaacata tgagaatctg ggccaaagca tttctctcac tccagctcat ttctgtggaa
     7861 ctcggatatc tcatgacttt atatattcaa agcttttaat ggtacctgtt acacagcaag
     7921 tactctgtga atgctgactc tgctgttctg atcgaggtgg gggaaggatg tgagggaagt
     7981 gagactatgc tggttaagca acaggtgcat ggcctgctta gggcagagtt gtgcttactc
     8041 ctttgctcac agacttggca gaacagattt gcccatattt gtgctgcagc agttaaatca
     8101 gccaacttgc agcccagggt ttgtaaatac ttgtttagga tttatgggtg cttagaattt
     8161 cacaagggct gaccttagac catctacctg ccaattcaag tttcctaccc atactttagt
     8221 aataaaaaaa tctacaacag ccagaatcaa gttttcaagg cttgtgtgtt tgttggtaaa
     8281 gaacaagtta ttataggaag catgcttagg atgctgttga ctcattttct ttgaggagtt
     8341 cttgtacctt gtgttatgct ggggcattcg atttcttgta ccttatttca tgctgggaca
     8401 ttcggtggaa cacatgtaca ctcatcagca tatgatgcct tccttctatc tgatactctt
     8461 agggcattac tattctattt ctatctctat ctgtttatct acctatttgg atacaattgg
     8521 gaagtttctt tttattacaa ggacaagtgt gttgatggtg aagttactgc tgctcaactg
     8581 agtaaagggc ttgtatctac catggaagtg ctggctcaca catgcttgca aagacttgat
     8641 cacagaagag ggtggacagg ttgagtccca ggctggtagg aggtgagtta tgtggaaaca
     8701 tagattgaat tccaagatgc tgtagtttta gaaaaaactc tggacaagga ttaactttaa
     8761 ggaggccagc tgaaactgtt ggtaggttct tcatctcact tatccaacat ttgaagcaag
     8821 gttcttaatg taggtatgca tgcatacaca tcaaaaaaca acccctgcca ataataacaa
     8881 caatcttaaa aaaaaacaaa aaacaaacaa acaaacaaaa aaaaacaaca aactacaaca
     8941 aaaaaagccc tgaccagtta tcagaggagg atcatggcct ttcttcttag aactttacca
     9001 tttgtgtaag tggctttgtt gcctcacaaa ggggtgtcgt aaagattgcc cccattgcag
     9061 tgaagaggaa tggttcacat cttctctttg ctgctgcatg gccatcagtg gcacatcgcc
     9121 tcagcacagt tgcaattggg atgttgctgg ccctcttctt cattcgatat tctccttcct
     9181 agtttccttt atacaacaac taactattcc aagtagttca gttagtggca gtctttgtgt
     9241 aggacttagg cttggccaac attttgacat cataacatat tgtcatctac agtgttcatg
     9301 tgacaactgt ataaaataac actgaaattg acaggaacta ttttggggtc aggaagagct
     9361 attttggagt gtgagtagca gatttaagaa gccagattgg gaatgaggaa ggaacattgc
     9421 tagaattggt attgtgggca tatgtggcac tggggcagtc ttaattctca ggcagccctc
     9481 ctggaggtgc tgttatttct gatctagaca tgaatctaat attcagggtt aactgctaga
     9541 gacaggaatg aatcccatct gttttttgta ccaaagctcc tctctgctca gcaggctaca
     9601 aattagaagg cagcagcgaa agctggcctg atttctaggc ctcctgtatt aaacatattt
     9661 ctgagcagaa cagaatacag ggatttttgc ttcttgggag tggggtgggg tcactgatga
     9721 taaaaggata tctaacaaac agagaatgaa gagaaagtgg actgttgaac agaggaagct
     9781 tttgtgtcga aagcttgttt tgtttggatg aagtatcaag agactgggat acctattttc
     9841 taataagttc ttcttcctgg gaatttattc tctgcttgag aaaggtaatg atggagtttg
     9901 agggatttgc tcctgggatc tggtataaag aggtagacct ggtcaggtgt agttaaggta
     9961 ggtagcccat caaaagaccc atgctgagca cttgacagtt tggaatgtga gtctttcctc
    10021 catcttgggc ctaaggttca gtgaacatta cttgagagct gcaggctctg tggatatatt
    10081 tgcttctcac catgttgttt acaggccact tcccaatttc ataaccaatt gcttaggggc
    10141 aggaagatgt ggggatccca ccttgccaga gctcttacca tctttgccaa ctgacacttt
    10201 ttctgcaaag catgctgtgc tccattggga aataggaaga aagaatctta ttctaaccaa
    10261 gttctagagc atcaaagtgt gaaggaatga gaggtctgga tggcacgcag agcactgcag
    10321 agccctctca ctttctgtgg tccatttcta gctctaaaga aatagtgatg caaggaatat
    10381 tgtttttcat ggaactaaaa ccccagaggt ctttgcaaac caccctgctt gtttgtggca
    10441 aaacactgtg gcttctaatt agtgagtatt gaaccacaca gaggaaatta catctctgtg
    10501 ctgctcttag ggttaacaga aactctacta ggaattggct ttgaatcctg taactgaagg
    10561 acttagaagt ttgctcttac taggaaaggg ccttaagtaa agtgacttta ctcaattaca
    10621 tagtgcttgg tggcagagtc ctcatgctct tgaatatgtt ctgcttacct ggtcctgtgc
    10681 attcctcact accctgcttc cttctcaaag gccatttaac tcttcttcta gactttgaga
    10741 ctatacagtg tgtgccttac aaaatggaat aaacagaaac caatgcagct cttcttttcc
    10801 ctttcctgtc ctagctcatg ctctccctgg ttcctgtgga aatggcacag tggaatattt
    10861 atagtcttgt gctgttacca aaactgtata taatgaagtg caacttagtg gatgctgctt
    10921 gagagatcct gggcttttag aaatgtggtc tttgggggga agttggctag tctgcatgtg
    10981 cttatttaac caaaggatca tcctcacagt ggtactttct ggagcagtct cacacaggga
    11041 tctgcttttt tttttttttt ttcgagacag gggttctctg tgtagccctg gctgtcctgg
    11101 aactcacttt gtagaccagg ctgcccttga actcagaaat tcgcctgcct ttgcctcccg
    11161 agtgctggga ttaaaggcgg gcaccaccac gcccagctag ggctctgctt tgtaggatct
    11221 gtcatacgta ctttagtcta cattaagaaa aatcatggat atcctccttt gagatgttaa
    11281 aacaaaagta tggagaatgt cacttgagga acttagaaag gcttacatca cttggaaaca
    11341 agatcaaagg accaggatgt caaggctagt gaaggggtgg ccttaggcaa acctgaataa
    11401 gtcttaccgg ttattttaaa ggattttatt tacttgtatg tggttccaga agggtgaaga
    11461 caactatgag tagacaagtg ggcattttga tgtgaaggtg ccacatgagg gcaggtgagg
    11521 tgctttggaa gaacagaagg taagaagtgt actgtgggat gtgatagcat atgctgaagc
    11581 tatgagctgc ctttggtggt gcatgaggaa gactgagttc atgccagcct tagctatgca
    11641 atgagaagct gtcaaaagcc acaggatgtc cattgtgatc acctgtgaca ggactgggag
    11701 acagtgctgg gagtagcttc tctttctttt tctttttcct tttccttttc cttttccttt
    11761 tttttttttt tttttttttt ttttgagaca gggtttctct gtgtagccct ggctgtcctg
    11821 gaactcagaa atccacctgc ctctgcctcc cgagtgctgg gattaaaggt gggagccacc
    11881 actgcctggc ttcattctac tttgtaaccc tctatttggc tctgctcagt gttgggaatg
    11941 tcacaagttt ttcagcttag gaggatggcc atgtatgtgt aaggtgcagg aaagggagag
    12001 agtgcatggc aagaggtgtg agcagaatca gagctgtagt ggaattgcta aagccagctg
    12061 ttctgctctt ccgctcatag agatgctagt cctggcttca ggatgcctaa tagacctgtt
    12121 ttcagttttg cagaccactg ggagaagacg caggtgggtg agttgactta cagcatagga
    12181 agtgcataga gctgagtcac aattgcagta gccctggtcc aagtccgcag gcctttagat
    12241 gggacagcac agagcaatga ggggattctg gaagggtcct tggcagggac atctgtgagc
    12301 agaagaaagt gcagcctgct agtcctcatg aaatgcttca gcatggttag tagggcgaga
    12361 tggtaggtgg gaggtatttc ccagaaccac tgtttgaaga tccctgggtg ctgtgccctt
    12421 tgtgattaca attcttcagt gtggtgagaa aattgtgaaa gaacatccag acagccaaga
    12481 accttgttgt gactgatgag aaaggggctg ttgccatgcc cagataagga tgaagggatt
    12541 tgcttgagtt gtagtagaga tggggtagca gtctcttcat aagcagatct gatagatctc
    12601 tctcctatcg gagagagtgg tgctgcctct gaccaggaag gcaatggtag tgtttatagc
    12661 cactggggtg gagcaagggc tcaaaatgga ctgggtagtt tgatgccagc cagttgatat
    12721 ctttactctt tttttttttt tttttttttt tttaaataag gctaattctg cccatcacaa
    12781 catgataggt attgaatatt cctttatact ggggtctgtc tttttgcttt catatagatt
    12841 tttttttttt ttaattttaa agatttagcc tgtaaaaggg ctagtgcctt ttgggaatca
    12901 gcatctgtag agtatagtct ttagccattg gaaaggtaca ttttctttac agagtttctt
    12961 acagaggaaa aaggtatgtg gttactgaaa gatttactct gggctttagc tgtgagttaa
    13021 tatccatcta gccatgtctc ctgggtgtta tggacaggaa accaggtggg aatcacaagg
    13081 aggtgtattt ttttcagtgc tgggaatgag agagtgtcac gcttcaaaac tagggccttg
    13141 tacatagtag gctgttactt caccagtgaa tgaatcagga tagatttctg cactattgaa
    13201 tttatgtacc tctgctgggg actagactgc tattatttgg aggccttagg tcagatcttt
    13261 ggaaaggtta aaggtatttg ggacaccaag tctgtcagtt tttgagcagt gagaactcca
    13321 gggacataca gatatcacct tctcattggt tacagtgaaa atcttttggc agccctcctc
    13381 ctatcctatg ccgatagcct tttcctttcc agaatccttc cataatttac tcaccacact
    13441 ggagaatggt aaacagctgg atggatggat gggagtgagc atgtagggca catagttgct
    13501 gtcacattct aaactctgcc actgtagcat gaaagcacct cagaatggta taggcattgg
    13561 tgagtgtggc tgtgttcaat cacatattac ttacatacca aagtgagtag ggctcaggaa
    13621 ggtccatgat gagctccaaa tggagggaag acatttgagt ggggaaagcc caagggaggc
    13681 agcagctatg ttgttagacc tagagggact atgtggttcc tcccagaaag aacagctcta
    13741 gatggtagag aggttgtgtc ccagctacaa gtttttgttt tcagaggcac ttgggctaga
    13801 ttggggctgc ttgggtgaca ggctgagggg cacagattat tctctaggtg gtgggtaacg
    13861 tgaccacaga cacattacat tcaataatgt cgttctgatt atggtagacc aatgcctgga
    13921 actacaaatt acacttttct gcttagtatg gactagatgt gtaagggctg aggtgctctt
    13981 agaattctga tgaaaagtgc agttggaatg ttggaaggtt ttcttgccag gatgacttag
    14041 tgatgaatga gtgctgttac atgacaattt cactaacagt gtttcattgc cttgctcttt
    14101 ttttgtatcc aggccaattt gggttttggg ccttggtgtg caaaggaaaa attgtgaatg
    14161 tacccctgtg tccccccccc cccccccaca ccctttagaa ccaaatcaca gagcaagaaa
    14221 gctgtatgta atgcaaactc acttaaagcc aggccttgca gctttctact gaaagttgag
    14281 tgctgccctg gtgcatcctg gaccttgagg gcaccctgct ctcctctagg taatttcctc
    14341 agggcagttt ttagccaggt tgagaagcat ctttcattta gaaagttcca acaacaactg
    14401 cttgctttca gtgagctttt gtgatctgca gccatccttc aaggtgatgt gcctaggaga
    14461 catgttggcc ttgcttagct tcctctagtg caatggttct caaccttcct aatactgctg
    14521 tctctttaat gcagttcctc acattgaggt gacccccagc caggagatca tttttgttac
    14581 tacttcataa ttataatttt gctactgtta agaatcatgc cagagcgggc tcgacccaca
    14641 ggttgagaat caatgttctt atacagatat gctgccttgg attttgctgc ctcgtaagat
    14701 atgggatagc tctgatgctg atagtagtat tcttcaaaat tttctagaga agtttctgag
    14761 ttcatggaag ggaatatgat ttgagtatgg aatagatgga aactggctca gtcttggcag
    14821 tgtgcagtct gtccttagct gatagcagga atatattttc tttctctctg gcttttcaag
    14881 acagggtttc tctgtgtatc tctggctgtc ctggaactcg atctatatag acctggctgc
    14941 tctcaaactc atagagatct gcctgcccct gcctcccatg tgctgggatt acagggtgtg
    15001 caccaccaca ttcggctcag gaatattctc ttatttggta gccaagttct gaaaagtgct
    15061 ctagcttata gggtggttcc tgtcacttgg catggtcagt caatgataga actttgcctg
    15121 ttgactgtgt catagccttc agttaatgcc atgatgatga tcaaaattaa aaaataagtg
    15181 aaaaactacg tcccttagct atttatgctg tagtaggagc cagaaaaaat gtttttgtac
    15241 cttgtcaatc ggtcaaggaa atgaatcaag agtaaggata ggagtcttta gaaagactgc
    15301 cttcgtttct tcctgtaatt tagaaagttg catttctagt ttctggcttc ttgcctttgg
    15361 ctgagtggtt gatatgctct acccttcctt gctgagcata cctttccact ctggccaagg
    15421 aacttggttc ttgttgacat aaacattctg gtttagtgaa taagtaacag gacacaaggc
    15481 tctaagtaaa cttgtcccct gaacacagtc atgccctaag gtatcgatgg tatccatctg
    15541 tgaagaagga tttggatgtg agcccacatt tcacaagtac tctactggac tgaagtgttg
    15601 ctgctaccag atacaggaag ccccttctct aacattcatc ttttatgctc aggctgcctg
    15661 gtgccatcac gtagcaatta ctcctcacaa gaaatctaaa gagatgaagc gctgttttcc
    15721 tcctaactca tttcacatga cagcttttta gtgacaggcc accctgtagt ctttactgat
    15781 gggcttatct acccttattc ctgtttctgg aaaggatact tagttgtaga aactgccaga
    15841 ctggggcaga gcatcctcag cctgtctagg gtccttgctc tatatcccag gaattgggag
    15901 tagcactggg ctcatgaagc acaccaaggc tcaaaacaag tactttgttc aggtccagga
    15961 ggtgaaaacc tatgttttgc aaagatacag gtggcatttt tctccaggct ttagcttact
    16021 cggttctgat gttggccaag ttagtgctta gaagtctgtt taaaataccc atttgtattt
    16081 actgttttcc caagtacaca gtgtaaatag tataatttgc agtgcaaagt ctttggcaat
    16141 aattttatga tgtatatact atgttaaaca ttggaaacca caagcaccat ggactgcccc
    16201 atgtcttctg ggcctgtggt gacatgtaga ctttggactt tccaagtatc agcgtgcttg
    16261 aagcagcagc ctgcatgtgt ggactatcat cagtgcctcg cccagagatg cctggccttc
    16321 atccaaaggg accctgctgc tccgagccca gcgagcagca cccacactgc ggctcctttg
    16381 tgttgaatat gttggactct gccatagact ccttgtttgg ctgctgcact ttgtaatgcc
    16441 ttgacatgtt gcatttcttt tccatttgga tgaataaaaa taaacgctgt gtcaaatagg
    16501 aa
//
