LOCUS       NM_011499               2644 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus serine/threonine kinase receptor associated protein
            (Strap), mRNA.
ACCESSION   NM_011499
VERSION     NM_011499.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2644)
  AUTHORS   Vu,T., Datta,A., Banister,C., Jin,L., Yuan,G., Samuel,T., Bae,S.,
            Eltoum,I.E., Manne,U., Zhang,B., Welner,R.S., Mitra,K.,
            Buckhaults,P. and Datta,P.K.
  TITLE     Serine-threonine Kinase Receptor-Associated Protein is a Critical
            Mediator of APC Mutation-Induced Intestinal Tumorigenesis Through a
            Feed-Forward Mechanism
  JOURNAL   Gastroenterology 162 (1), 193-208 (2022)
   PUBMED   34520730
  REMARK    GeneRIF: Serine-threonine Kinase Receptor-Associated Protein is a
            Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis
            Through a Feed-Forward Mechanism.
REFERENCE   2  (bases 1 to 2644)
  AUTHORS   Jin,L., Chen,Y., Crossman,D.K., Datta,A., Vu,T., Mobley,J.A.,
            Basu,M.K., Scarduzio,M., Wang,H., Chang,C. and Datta,P.K.
  TITLE     STRAP regulates alternative splicing fidelity during lineage
            commitment of mouse embryonic stem cells
  JOURNAL   Nat Commun 11 (1), 5941 (2020)
   PUBMED   33230114
  REMARK    GeneRIF: STRAP regulates alternative splicing fidelity during
            lineage commitment of mouse embryonic stem cells.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2644)
  AUTHORS   Anantha,J., Goulding,S.R., Wyatt,S.L., Concannon,R.M.,
            Collins,L.M., Sullivan,A.M. and O'Keeffe,G.W.
  TITLE     STRAP and NME1 Mediate the Neurite Growth-Promoting Effects of the
            Neurotrophic Factor GDF5
  JOURNAL   iScience 23 (9), 101457 (2020)
   PUBMED   32853992
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2644)
  AUTHORS   Hu,X. and Mullins,R.D.
  TITLE     LC3 and STRAP regulate actin filament assembly by JMY during
            autophagosome formation
  JOURNAL   J Cell Biol 218 (1), 251-266 (2019)
   PUBMED   30420355
  REMARK    GeneRIF: LC3 and STRAP regulate actin filament assembly by JMY
            during autophagosome formation.
REFERENCE   5  (bases 1 to 2644)
  AUTHORS   Moore,K.S., Yagci,N., van Alphen,F., Meijer,A.B., 't Hoen,P.A.C.
            and von Lindern,M.
  TITLE     Strap associates with Csde1 and affects expression of select
            Csde1-bound transcripts
  JOURNAL   PLoS One 13 (8), e0201690 (2018)
   PUBMED   30138317
  REMARK    GeneRIF: Strap associates with Csde1 and affects expression of
            select Csde1-bound transcripts
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2644)
  AUTHORS   Carissimi,C., Saieva,L., Baccon,J., Chiarella,P., Maiolica,A.,
            Sawyer,A., Rappsilber,J. and Pellizzoni,L.
  TITLE     Gemin8 is a novel component of the survival motor neuron complex
            and functions in small nuclear ribonucleoprotein assembly
  JOURNAL   J Biol Chem 281 (12), 8126-8134 (2006)
   PUBMED   16434402
REFERENCE   7  (bases 1 to 2644)
  AUTHORS   Tretyakova,I., Zolotukhin,A.S., Tan,W., Bear,J., Propst,F.,
            Ruthel,G. and Felber,B.K.
  TITLE     Nuclear export factor family protein participates in cytoplasmic
            mRNA trafficking
  JOURNAL   J Biol Chem 280 (36), 31981-31990 (2005)
   PUBMED   16014633
REFERENCE   8  (bases 1 to 2644)
  AUTHORS   Chen,W.V., Delrow,J., Corrin,P.D., Frazier,J.P. and Soriano,P.
  TITLE     Identification and validation of PDGF transcriptional targets by
            microarray-coupled gene-trap mutagenesis
  JOURNAL   Nat Genet 36 (3), 304-312 (2004)
   PUBMED   14981515
REFERENCE   9  (bases 1 to 2644)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 2644)
  AUTHORS   Datta,P.K., Chytil,A., Gorska,A.E. and Moses,H.L.
  TITLE     Identification of STRAP, a novel WD domain protein in transforming
            growth factor-beta signaling
  JOURNAL   J Biol Chem 273 (52), 34671-34674 (1998)
   PUBMED   9856985
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK147179.1 and AK145971.1.
            
            On Nov 20, 2007 this sequence version replaced NM_011499.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147179.1, AK154158.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                AK147179.1         2-50
            50-2643             AK145971.1         2-2595
            2644-2644           AK147179.1         2646-2646
FEATURES             Location/Qualifiers
     source          1..2644
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 67.27 cM"
     gene            1..2644
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /note="serine/threonine kinase receptor associated
                     protein"
                     /db_xref="GeneID:20901"
                     /db_xref="MGI:MGI:1329037"
     exon            1..385
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            386..521
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            522..603
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            604..676
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            677..773
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            774..911
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1048
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1198
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1264
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..2644
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1790..1795
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /note="hexamer: AATAAA"
     polyA_site      1810
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /note="major polyA site"
     regulatory      2276..2281
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Strap"
                     /gene_synonym="Unrip"
                     /note="hexamer: AATAAA"
     polyA_site      2293
                     /gene="Strap"
                     /gene_synonym="Unrip"
ORIGIN      
        1 gtcacttccg gctgacgcga cgcgtcgggc gacgtcacgt cctgccgcta ccggtaggga
       61 ccgtgagtgg cggcaggccg gctctccggc gctcccctcc cctcctccct ccctccctgt
      121 ccctcccttg gcggccgcga gtcgcgggga ctctggagcc ggcctccttc ggcgtgagtg
      181 cgggggcctc aagcagcctg aggcgccgcg gcagagaagg aggacgaccg cgaccctcgg
      241 tccccgctcc gcgtcaccgc gctcgccgcc gccatggcca tgaggcagac gccgctcact
      301 tgctcgggcc acacgcggcc cgtggtggat ttggccttca gcggcatcac gccttacggc
      361 tactttctga tcagcgcttg caaagatggc aagcccatgc tccgccaggg agatacagga
      421 gactggattg gaacattttt gggtcataaa ggtgctgttt ggggtgcaac attgaataag
      481 gatgccacca aagctgcgac agcagctgca gacttcacag ccaaagtatg ggatgcggtc
      541 tcaggagatg aattgatgac cctggctcat aagcacattg tcaagactgt ggatttcaca
      601 caggatagca attacctgct aactggggga caggataaac tgctgcgcat atatgacttg
      661 aacaaacctg aagcagaacc taaggaaatc agtggccaca cttctggtat taaaaaggct
      721 ctgtggtgca gtgacgataa acagatcctt tcagcggatg ataaaactgt tcggctctgg
      781 gatcatgcca caatgacaga agtgaaatct ctgaatttta atatgtctgt tagcagcatg
      841 gagtatattc ctgaaggaga gattttggtt attacttatg gacgatctat tgcttttcat
      901 agtgcagtaa gtctggagcc aattaaatcc tttgaagctc ctgcgaccat caattctgcg
      961 tctcttcatc cagagaagga gtttcttgtt gcgggtggag aagactttaa actgtacaag
     1021 tatgattata acagtggaga agagttagaa tcctacaaag gtcactttgg tcccattcac
     1081 tgtgtgagat tcagtcctga tggggaactc tatgccagcg gttctgaaga tgggacattg
     1141 agattgtggc aaactgtggt aggaaagacc tatggcctgt ggaaatgcgt gcttcctgag
     1201 gaagacagcg gggaactggc aaagccaaag atcggatttc cagaaacagc agaggaagag
     1261 ctggaagaaa ttgcttcaga gaattcagat tccatctatt catcaactcc tgaagttaag
     1321 gcctgagcat cagacgtgtg ctgccgaaac catatgttca tggactaaac aagcagagac
     1381 aagcatccgc cttcagagtt actgtctgcc tgaggcaaag agggcagaaa atattggggc
     1441 atatgagtta gctccagtgc acgaacagct actcagtgtt gcccgtgagt gaaaatggct
     1501 gagtgtctga ggtgcaggca ggaggattgt gctcacatag tgccatagcc tgctgtttgg
     1561 aatgaaaagc caacttacaa tctccatttt acacctaaat ttcttttagc tgtttatgtt
     1621 atgaagaaga aaaatatatt ggcctatttt tctgactttc ccttaaagaa gaatgccttt
     1681 ttgtccttgc ctagtgatga agaggaggaa atacatgata aagtaaccgg tttgatctct
     1741 ttcattgtac aaggactgct tcagaacagc tcatattttt agttatctaa ataaaatgcc
     1801 tctaaaataa taatttttct ctttttttgg aaattctgat acatttgaat actaaaacta
     1861 actattcaaa gttttctata tcatacacag ccagccagag caaagacagt ttggttatag
     1921 agtctgaact aaacatttcc taaatttgaa attgaattat ttaaacttga aattttcata
     1981 tcttttgttg tgtgttcatt tatttccttc tggatggata caattgcttc tcttgtctct
     2041 ttaaacatgc atgttagtta ctaaaacaga aaaacactta ggaagagcaa gtaaacaagt
     2101 tgaaatctca gttctgaaaa tattctgaaa aactgctgta cgtagtctaa catctgctcg
     2161 gttgtacaaa taaccacatg atttaatgaa actgggttaa tcattaattt tcagtattta
     2221 tgatatacca aactttctca tatttaaact tgggtcattc aaaaagtcaa cctttaataa
     2281 attggataat aaatttgtag tttatttact tattttacaa tgtgaagaga ttaagttagt
     2341 aatttggaaa tacagatgaa cagcttgtat taatttgctt tctggtaatt tatcttctga
     2401 gtggccttta gtactttgat cagaaaagtc tcgactagtt tgtgactaga agttggcggc
     2461 actacaggcg gttcctggga gagccaggga agcccgtcac aggcattgat gagcctcagg
     2521 cagtggtgtt cccctgtcca tgtttaacat gcttggtttt ctgctctgta gcagtattgt
     2581 tcatgtatca agattagact gagagtctga ccctaaataa aattgagtgc atcttttgta
     2641 atgg
//
