LOCUS       NM_028788               3608 bp    mRNA    linear   ROD 11-FEB-2025
DEFINITION  Mus musculus STRA6-like (Stra6l), transcript variant 1, mRNA.
ACCESSION   NM_028788 XM_283962
VERSION     NM_028788.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3608)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3608)
  AUTHORS   Radhakrishnan,R., Leung,M., Roehrich,H., Walterhouse,S.,
            Kondkar,A.A., Fitzgibbon,W., Biswal,M.R. and Lobo,G.P.
  TITLE     Mice Lacking the Systemic Vitamin A Receptor RBPR2 Show Decreased
            Ocular Retinoids and Loss of Visual Function
  JOURNAL   Nutrients 14 (12), 2371 (2022)
   PUBMED   35745101
  REMARK    GeneRIF: Mice Lacking the Systemic Vitamin A Receptor RBPR2 Show
            Decreased Ocular Retinoids and Loss of Visual Function.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3608)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   4  (bases 1 to 3608)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 3608)
  AUTHORS   Berry,D.C., Jacobs,H., Marwarha,G., Gely-Pernot,A., O'Byrne,S.M.,
            DeSantis,D., Klopfenstein,M., Feret,B., Dennefeld,C., Blaner,W.S.,
            Croniger,C.M., Mark,M., Noy,N. and Ghyselinck,N.B.
  TITLE     The STRA6 receptor is essential for retinol-binding protein-induced
            insulin resistance but not for maintaining vitamin A homeostasis in
            tissues other than the eye
  JOURNAL   J Biol Chem 288 (34), 24528-24539 (2013)
   PUBMED   23839944
REFERENCE   6  (bases 1 to 3608)
  AUTHORS   Alapatt,P., Guo,F., Komanetsky,S.M., Wang,S., Cai,J., Sargsyan,A.,
            Rodriguez Diaz,E., Bacon,B.T., Aryal,P. and Graham,T.E.
  TITLE     Liver retinol transporter and receptor for serum retinol-binding
            protein (RBP4)
  JOURNAL   J Biol Chem 288 (2), 1250-1265 (2013)
   PUBMED   23105095
REFERENCE   7  (bases 1 to 3608)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   8  (bases 1 to 3608)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY776586.1, AK050348.1, AK050152.1 and AL772381.5.
            
            On Mar 11, 2015 this sequence version replaced NM_028788.3.
            
            Transcript Variant: This variant (1) encodes the longer isoform.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK050152.1, AK004855.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                BY776586.1         65-82
            19-2526             AK050348.1         3-2510
            2527-3602           AK050152.1         2515-3590
            3603-3608           AL772381.5         116810-116815
FEATURES             Location/Qualifiers
     source          1..3608
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 24.39 cM"
     gene            1..3608
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /note="STRA6-like"
                     /db_xref="GeneID:74152"
                     /db_xref="MGI:MGI:1921402"
     exon            1..151
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..1997
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /note="isoform 1 is encoded by transcript variant 1; RBP4
                     receptor 2; STRA6-like protein; retinol-binding protein 4
                     receptor 2; stimulated by retinoic acid gene 6
                     protein-like"
                     /codon_start=1
                     /product="stimulated by retinoic acid gene 6 protein-like
                     isoform 1"
                     /protein_id="NP_083064.2"
                     /db_xref="CCDS:CCDS18141.1"
                     /db_xref="GeneID:74152"
                     /db_xref="MGI:MGI:1921402"
                     /translation="MLAASTRTRQINITCDNPVDREVFLHYSLIPSLCIILVLSFLQR
                     REHRRQRDDTSYLLGNHFGIIVPLDFVGTFSNRWSYGAAFGATANKVMFLFSEGYQPL
                     TVPQWAQAFVLFIGGMEVGLSYFPFFACLSSEFQLVSSILGFSYSLTWFVVTVLQISQ
                     CPHGQFLGRFETLVFYWPSLLCLGFLLGRFLHMFLKALPVHLGLEPQTEEKSMLEAHQ
                     AKHVKQLLSKPRPQEGEKSWFQTRVYEWDPCFQFPSRMVGTLLLAFICLYLFIVIEFC
                     VFLHVRDKLDMFEDKLESYLTHMNETGTLTPIILQVKELISVTKGVWVVTILPAALTC
                     VTYLFHILACYRKHMKRLWAGDKHFLPQKFHSPSSAASVVAIARYSGWQIAYILWGYL
                     IIHVVQSLCGVMLMYGLVLPIIHHRGLEMLQGFGLGVLTLSIVVGLIILQVWIAGTFF
                     LQPKLGTSDKQKPLALNNRRAFHNFNYFLFFYNVLLGLGACLSRLLISCLLGTWLIAR
                     IDRTIMQSGYEGADMGFGAWIGMLFVDHYHTNPVLVSFCHILITSHKDRKLQKTVKYW
                     CLNQSAGPRFSARARTRWFLLQTLINNPRLVMLRKSKSGHSSGEFTQILLTCSDC"
     exon            152..227
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            228..328
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            329..459
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            460..580
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            581..626
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            627..755
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            756..826
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            827..938
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1092
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1168
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1250
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1251..1299
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1417
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1537
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1538..1701
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1848
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..3608
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3585..3590
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /note="hexamer: AATAAA"
     polyA_site      3605
                     /gene="Stra6l"
                     /gene_synonym="1300002K09Rik; Rbpr2"
                     /note="major polyA site"
ORIGIN      
        1 agtctgggtc tacagatcaa actggggaga ataggagctc atgggaagcc gtcataaaca
       61 agcttccgag gaacggagca gccccaggac cgcagcatcc acagtaccgc gcacagtcgt
      121 ccttcagcaa gatgcttgct gccagcacaa gaaccaggca gataaatatc acctgtgaca
      181 acccagtgga ccgggaggtc ttcctccatt actccctcat tccatcactc tgcatcattt
      241 tggtcttgtc tttcctccaa agacgagagc atcggagaca aagagatgac acctcctacc
      301 tcctggggaa ccactttgga atcatcgtgc ctctggactt cgtggggact tttagtaacc
      361 gatggtccta tggagctgcc tttggggcca cagccaataa ggtcatgttc ttgttctcag
      421 aaggctacca gcccctgacg gttcctcagt gggcccaagc ctttgtgctt ttcatcggag
      481 gcatggaggt cggcctctcc tacttccctt tctttgcctg cctgtcctca gagttccagc
      541 tggtcagctc catcctgggc ttcagctact ccctgacctg gtttgtggtt actgttcttc
      601 agatctcaca gtgtccccat gggcagtttc tggggaggtt cgagaccctc gttttctact
      661 ggccctcact gttgtgcctg ggtttcctgc tgggtcgttt cctgcacatg ttccttaagg
      721 ctctgcctgt ccacctgggc ctggagccgc agacagaaga aaagtcgatg ctggaagccc
      781 accaggcaaa gcacgtgaag cagctcttga gcaagccccg cccacaagaa ggcgaaaagt
      841 cttggtttca aaccagggtg tatgagtggg acccctgctt ccagtttccc agcaggatgg
      901 tcgggaccct gctgctggcg ttcatctgcc tctacctttt catcgtcatt gagttttgtg
      961 tgtttctgca cgtgagagac aagctggaca tgtttgaaga caaactggag agctacctca
     1021 cccatatgaa cgagacgggg accttgaccc caatcatctt acaggtgaaa gaactgatca
     1081 gcgttactaa aggagtctgg gtggtgacca ttttgcctgc cgccctcaca tgtgtcacct
     1141 atctcttcca cattctagcc tgttacagaa agcatatgaa gaggctatgg gctggagaca
     1201 aacacttcct ccctcagaag ttccacagtc cctcttcagc agcaagtgtg gtggccattg
     1261 caaggtactc tggctggcag atagcctaca tcctctgggg ctacctcatc atccatgtgg
     1321 ttcagagcct ctgtggggtg atgctcatgt acggcctggt gctgcccatc atccaccacc
     1381 gaggcctgga gatgctgcaa ggatttggcc ttggggtcct caccctgtcc atagtcgtgg
     1441 gccttataat cctacaagtg tggattgctg gcacgttctt cctgcagcca aagctgggca
     1501 catccgacaa gcagaagccc ctggctctca acaacaggag agccttccac aacttcaact
     1561 acttcctgtt tttctacaac gtgctgctgg gcctgggggc ctgcctctcc aggctgctca
     1621 tcagctgcct cctgggcact tggctgatcg cacgcatcga caggaccatc atgcagagtg
     1681 gctatgaggg tgcagacatg ggctttggtg cgtggattgg tatgctcttt gtggatcact
     1741 accacaccaa ccctgtgttg gtcagctttt gccacattct gatcacaagc cacaaggaca
     1801 ggaagctgca gaagactgtg aaatactggt gcctgaacca gtcagcaggt ccccgcttct
     1861 cggccagagc cagaacgagg tggttcctgc tgcagacgct gatcaacaat cccaggcttg
     1921 tcatgctcag aaaatcaaaa tcaggtcata gttcgggcga gttcacacag attctgttga
     1981 cctgctcaga ctgctgattg ggccgccaac ttctgctcca aggccaggcc atcccctctc
     2041 acaaggacct cagcttacct agcagccatt ccctacaatg gcacaggaca acatgggcac
     2101 tgttcctgca catgatagac ggcactgacc acttgtgggg tggccatata gaccaatggt
     2161 ttaagcctag catgatctca gtcccttggc acaaaagaaa aacaatataa aaagcaatgt
     2221 ctgtggagca aattttgccc atcagtgacc tccactattt gtgggaaggc ctccatgggg
     2281 tcatctatta agaagcatga aatagaggct ggataaatga gacggctcag gggctgagtg
     2341 cattagattt cacttgcaga ggactcaagt ttggttccta gcctctacac tgggcagctc
     2401 acaagtgtct gtaactctag ggatctgacc tgtttccagc ctattcaggc acctgcacaa
     2461 atgtggcaga cacatataca tataagtaaa aacaattttt taaaaatgaa tctttaaagt
     2521 aattttaaaa aagtagtatg aagtgaactt tctgccctat gacctactgg gaatggaatc
     2581 agagatgata taggacttcc tcctaaagat agtctgagtc tatctgtggg atcacctacg
     2641 aaagccaagc agaggtggaa tgggcctgca ttccaggtgg agtgcagcaa cactgataca
     2701 gggtgagcag gagaccccag gcattttgat gatggtgttc atgcagcatg ttggatacaa
     2761 tgctgaaaga agatgaggct tactcaagag acacaagtgt caggctggga ggtgtggaca
     2821 ttgtccttat gtaaagccag tactacccga attttcatac tcaaaatggc caggacagat
     2881 acagtctgac cattgaaagt ctctcctgag cctgagcaag tgccgtgagg acccaaagtc
     2941 tccgagtgct tgcacctggt tgctatgtac acttggtcct gttggcgcat gcgtcagagt
     3001 tgtctctttt agctgaatct ttacaacagc cctttgacaa tttgttttga gaaaatgaag
     3061 agccatctcc ccactcccca cacaacactc gtcactttcc agctctgtgg tcaaacaact
     3121 ttttctttct ctattcacag atatttatat ctgcaaaagg gggccaacat cccaactcca
     3181 tgtatcagct tgagaataaa attattaaaa gcacttagac acttttaagc ttgtgcctga
     3241 cactctaaac actcaaaagc agactcggtt ttgattgtct ctatggtttg agtgtaaaca
     3301 atgtctccca caggcccagg tacctgtaaa gaccttggtc cctaggatgg caccatgcag
     3361 agggatggca cctttggggc tggtgcctag taggaggtcc ttaagtcact ggaggcatgt
     3421 ccttgaagga gatcatggga ctctagtctt tctgtttctt aactgatagg atgactattt
     3481 ttgcttacta gacatcccta ccccacatga catggtgcct cattagaagc caaaatcaat
     3541 gggacattcc ttcttagact gtggcctcca aaaccatgaa ctcaaataaa tttttgctct
     3601 ccatacat
//
