LOCUS       NM_001310522            1409 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus stathmin-like 4 (Stmn4), transcript variant 1, mRNA.
ACCESSION   NM_001310522 XM_006519315
VERSION     NM_001310522.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Hanemaaijer ES, Margaritis T, Sanders K, Bos FL, Candelli T,
            Al-Saati H, van Noesel MM, Meyer-Wentrup FAG, van de Wetering M,
            Holstege FCP and Clevers H.
  TITLE     Single-cell atlas of developing murine adrenal gland reveals
            relation of Schwann cell precursor signature to neuroblastoma
            phenotype
  JOURNAL   Proc Natl Acad Sci U S A 118 (5) (2021)
   PUBMED   33500353
REFERENCE   2  (bases 1 to 1409)
  AUTHORS   Martel G, Uchida S, Hevi C, Chevere-Torres I, Fuentes I, Park YJ,
            Hafeez H, Yamagata H, Watanabe Y and Shumyatsky GP.
  TITLE     Genetic Demonstration of a Role for Stathmin in Adult Hippocampal
            Neurogenesis, Spinogenesis, and NMDA Receptor-Dependent Memory
  JOURNAL   J Neurosci 36 (4), 1185-1202 (2016)
   PUBMED   26818507
REFERENCE   3  (bases 1 to 1409)
  AUTHORS   Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H,
            Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T,
            Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P,
            Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ,
            Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD,
            Flicek P, Skarnes WC, Mallon AM and Parkinson H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 1409)
  AUTHORS   Mei L and Xiong WC.
  TITLE     Neuregulin 1 in neural development, synaptic plasticity and
            schizophrenia
  JOURNAL   Nat Rev Neurosci 9 (6), 437-452 (2008)
   PUBMED   18478032
  REMARK    Review article
REFERENCE   5  (bases 1 to 1409)
  AUTHORS   Ohkawa N, Hashimoto K, Hino T, Migishima R, Yokoyama M, Kano M and
            Inokuchi K.
  TITLE     Motor discoordination of transgenic mice overexpressing a
            microtubule destabilizer, stathmin, specifically in Purkinje cells
  JOURNAL   Neurosci Res 59 (1), 93-100 (2007)
   PUBMED   17640754
  REMARK    GeneRIF: These data indicate that the overexpression of stathmin
            disrupts dendritic microtubule,organization, motor protein
            distribution, and neural function in Purkinje cells.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ062344.1, BC046752.1, CO427355.1, BQ178328.1 and CD776693.1.
            
            [WARNING] On Oct 4, 2023 this sequence was replaced by
            NM_001310522.2.
            
            On Jul 15, 2015 this sequence version replaced XM_006519315.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU846620.1, FO710551.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                CJ062344.1         2-80
            80-304              BC046752.1         1-225
            305-598             CO427355.1         228-521
            599-1224            BQ178328.1         66-691
            1225-1386           CD776693.1         18-179              c
            1387-1409           BC046752.1         1227-1249
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 34.48 cM"
     gene            1..1409
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /note="stathmin-like 4"
                     /db_xref="GeneID:56471"
                     /db_xref="MGI:MGI:1931224"
     exon            1..116
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /inference="alignment:Splign:2.1.0"
     exon            117..208
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /inference="alignment:Splign:2.1.0"
     CDS             196..846
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     stathmin-4; stathmin-like protein B3; stathmin-like
                     protein RB3"
                     /codon_start=1
                     /product="stathmin-4 isoform 1"
                     /protein_id="NP_001297451.1"
                     /db_xref="CCDS:CCDS79339.1"
                     /db_xref="GeneID:56471"
                     /db_xref="MGI:MGI:1931224"
                     /translation="MTLAAYKEKMKELPLVSLFCSCFLSDPLNKSSYKYEGWCGRQCR
                     RKGQSQRKGSADWRERREQADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPSFDG
                     VPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEE
                     NNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR"
     exon            209..304
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /inference="alignment:Splign:2.1.0"
     exon            305..385
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /inference="alignment:Splign:2.1.0"
     exon            386..594
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /inference="alignment:Splign:2.1.0"
     exon            595..786
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /inference="alignment:Splign:2.1.0"
     exon            787..1392
                     /gene="Stmn4"
                     /gene_synonym="Lagl; RB3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcggaggtga tgtcatgatg agagcccagc agtggtgctg atgttgagag aagcccaggg
       61 taccactaat tgaaggagtg agaagagaac agctcgcttt ggaaaccgga ctgcagggct
      121 gtgatccagt tctgagctgg tgataaacac tcccctgtga cttttggtca attcagccac
      181 cagattccag ccaacatgac tcttgcagcc tataaggaga agatgaagga actcccacta
      241 gtgtctctgt tctgctcttg cttcttgtct gatcccctga ataaatcatc ctacaaatat
      301 gaaggctggt gtgggagaca gtgtaggagg aaaggtcaaa gccagcggaa aggcagtgct
      361 gactggagag aaagaagaga acaggcagat acagtagacc tgaactggtg cgtcatctct
      421 gatatggaag tcatcgagct gaacaagtgc acctcgggcc agtcctttga agtcatcttg
      481 aagccacctt cctttgacgg ggtgcctgag tttaatgcct ccctcccaag acggcgagac
      541 ccatcattag aagagattca gaagaagcta gaagcagcag aggagcgaag gaagtaccag
      601 gaagctgaac tcctgaaaca cctcgcggag aaacgagagc acgagcgaga ggtgatccag
      661 aaagctatcg aagaaaacaa taacttcatc aagatggcaa aagagaagct ggcccagaag
      721 atggagtcca ataaggagaa ccgggaggcc catctggctg ccatgttgga gcggctgcaa
      781 gagaaggaca agcacgcaga ggaggtgcgg aaaaacaagg agctgaagga agaggcctcc
      841 aggtaaagcc cagaggccaa ggaagtttcc aggacagccg gacagctccc gtagcaacct
      901 ggttccagca gcctcggctg ctggctgctc tcccagcact ggggttcggg gggagggggg
      961 tggccaaggg gcgtttcctc tgcttttggt gtttgtacat gtaaaagatt gaccagtgaa
     1021 gccatcctat ttgtttctgg ggaacaatga tggggtggga gaggggacag tgagcgtgtg
     1081 gaagagggag gtgaagatga gcccaaggac attgtgacac tgtccactga ctgcagactt
     1141 gggccaaggc ccccgctttt catggctctg cctggacatc cggcctccag gttccgagtg
     1201 gagagaagat gagaactggg gtagaagttc agagtgaagg gcagagtcct ggcggggtgg
     1261 tggctgcagg gccagcagga caagcccgtc tggatggagt gagacctgcc ctgcagcggg
     1321 tgggataagg tctgtgtgcg tctgttcatt gtcatctttt gatcatcatg accaatgaaa
     1381 catttacttc caaaaaaaaa aaaaaaaaa
//
