LOCUS       NM_019641               1070 bp    mRNA    linear   ROD 05-FEB-2024
DEFINITION  Mus musculus stathmin 1 (Stmn1), mRNA.
ACCESSION   NM_019641
VERSION     NM_019641.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Ramlogan-Steel,C.A., Steel,J.C., Fathallah,H., Iancu-Rubin,C. and
            Atweh,G.F.
  TITLE     Stathmin 1 deficiency induces erythro-megakaryocytic defects
            leading to macrocytic anemia and thrombocythemia in Stathmin 1
            knock out mice
  JOURNAL   Blood Cells Mol Dis 87, 102522 (2021)
   PUBMED   33260083
  REMARK    GeneRIF: Stathmin 1 deficiency induces erythro-megakaryocytic
            defects leading to macrocytic anemia and thrombocythemia in
            Stathmin 1 knock out mice.
REFERENCE   2  (bases 1 to 1070)
  AUTHORS   Haglin,S., Berghard,A. and Bohm,S.
  TITLE     Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons
            Activates Dormant Tissue-Specific Stem Cells and Accelerates
            Age-Related Metaplasia
  JOURNAL   J Neurosci 40 (21), 4116-4129 (2020)
   PUBMED   32385093
REFERENCE   3  (bases 1 to 1070)
  AUTHORS   Kwon,Y., Jeon,Y.W., Kwon,M., Cho,Y., Park,D. and Shin,J.E.
  TITLE     betaPix-d promotes tubulin acetylation and neurite outgrowth
            through a PAK/Stathmin1 signaling pathway
  JOURNAL   PLoS One 15 (4), e0230814 (2020)
   PUBMED   32251425
  REMARK    GeneRIF: betaPix-d regulates the phosphorylation of Stathmin1 in a
            PAK-dependent manner.
            Erratum:[PLoS One. 2020 May 13;15(5):e0233327. PMID: 32401784]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1070)
  AUTHORS   Han,S., Fink,J., Jorg,D.J., Lee,E., Yum,M.K., Chatzeli,L.,
            Merker,S.R., Josserand,M., Trendafilova,T., Andersson-Rolf,A.,
            Dabrowska,C., Kim,H., Naumann,R., Lee,J.H., Sasaki,N., Mort,R.L.,
            Basak,O., Clevers,H., Stange,D.E., Philpott,A., Kim,J.K.,
            Simons,B.D. and Koo,B.K.
  TITLE     Defining the Identity and Dynamics of Adult Gastric Isthmus Stem
            Cells
  JOURNAL   Cell Stem Cell 25 (3), 342-356 (2019)
   PUBMED   31422913
REFERENCE   5  (bases 1 to 1070)
  AUTHORS   Maucuer,A., Camonis,J.H. and Sobel,A.
  TITLE     Stathmin interaction with a putative kinase and coiled-coil-forming
            protein domains
  JOURNAL   Proc Natl Acad Sci U S A 92 (8), 3100-3104 (1995)
   PUBMED   7724523
REFERENCE   6  (bases 1 to 1070)
  AUTHORS   Okazaki,T., Yoshida,B.N., Avraham,K.B., Wang,H., Wuenschell,C.W.,
            Jenkins,N.A., Copeland,N.G., Anderson,D.J. and Mori,N.
  TITLE     Molecular diversity of the SCG10/stathmin gene family in the mouse
  JOURNAL   Genomics 18 (2), 360-373 (1993)
   PUBMED   8288240
  REMARK    Erratum:[Genomics 1994 May 1;21(1):298]
REFERENCE   7  (bases 1 to 1070)
  AUTHORS   Mock,B.A., Krall,M.M., Padlan,C., Dosik,J.K. and Schubart,U.K.
  TITLE     The gene for Lap18, leukemia-associated phosphoprotein p18
            (metablastin), maps to distal mouse chromosome 4
  JOURNAL   Mamm Genome 4 (8), 461-462 (1993)
   PUBMED   8104060
REFERENCE   8  (bases 1 to 1070)
  AUTHORS   Schubart,U.K., Xu,J., Fan,W., Cheng,G., Goldstein,H., Alpini,G.,
            Shafritz,D.A., Amat,J.A., Farooq,M., Norton,W.T. et al.
  TITLE     Widespread differentiation stage-specific expression of the gene
            encoding phosphoprotein p19 (metablastin) in mammalian cells
  JOURNAL   Differentiation 51 (1), 21-32 (1992)
   PUBMED   1280608
REFERENCE   9  (bases 1 to 1070)
  AUTHORS   Pampfer,S., Fan,W., Schubart,U.K. and Pollard,J.W.
  TITLE     Differential mRNA expression of the phosphoprotein p19/SCG10 gene
            family in mouse preimplantation embryos, uterus, and placenta
  JOURNAL   Reprod Fertil Dev 4 (2), 205-211 (1992)
   PUBMED   1438949
REFERENCE   10 (bases 1 to 1070)
  AUTHORS   Zhu,X.X., Kozarsky,K., Strahler,J.R., Eckerskorn,C., Lottspeich,F.,
            Melhem,R., Lowe,J., Fox,D.A., Hanash,S.M. and Atweh,G.F.
  TITLE     Molecular cloning of a novel human leukemia-associated gene.
            Evidence of conservation in animal species
  JOURNAL   J Biol Chem 264 (24), 14556-14560 (1989)
   PUBMED   2760073
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669982.10 and BC031831.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by NM_019641.5.
            
            On Oct 24, 2009 this sequence version replaced NM_019641.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC031831.1, AK012231.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-92                AL669982.10        127624-127715
            93-1070             BC031831.1         1-978
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 66.76 cM"
     gene            1..1070
                     /gene="Stmn1"
                     /gene_synonym="19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17;
                     Pp18; Pp19; Pr22; Smn"
                     /note="stathmin 1"
                     /db_xref="GeneID:16765"
                     /db_xref="MGI:MGI:96739"
     exon            1..110
                     /gene="Stmn1"
                     /gene_synonym="19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17;
                     Pp18; Pp19; Pr22; Smn"
                     /inference="alignment:Splign:2.1.0"
     exon            111..183
                     /gene="Stmn1"
                     /gene_synonym="19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17;
                     Pp18; Pp19; Pr22; Smn"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..620
                     /gene="Stmn1"
                     /gene_synonym="19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17;
                     Pp18; Pp19; Pr22; Smn"
                     /note="oncoprotein 18; phosphoprotein p19;
                     leukemia-associated gene protein; leukemia-associated
                     phosphoprotein p18; metablastin; prosolin; oncoprotein18"
                     /codon_start=1
                     /product="stathmin"
                     /protein_id="NP_062615.1"
                     /db_xref="CCDS:CCDS18772.1"
                     /db_xref="GeneID:16765"
                     /db_xref="MGI:MGI:96739"
                     /translation="MASSDIQVKELEKRASGQAFELILSPRSKESVPDFPLSPPKKKD
                     LSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLT
                     HKMEANKENREAQMAAKLERLREKDKHVEEVRKNKESKDPADETEAD"
     exon            184..356
                     /gene="Stmn1"
                     /gene_synonym="19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17;
                     Pp18; Pp19; Pr22; Smn"
                     /inference="alignment:Splign:2.1.0"
     exon            357..548
                     /gene="Stmn1"
                     /gene_synonym="19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17;
                     Pp18; Pp19; Pr22; Smn"
                     /inference="alignment:Splign:2.1.0"
     exon            549..1060
                     /gene="Stmn1"
                     /gene_synonym="19k; Lag; Lap18; Op18; P18; P19; Pig; Pp17;
                     Pp18; Pp19; Pr22; Smn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagccaatg cggagcgcct ggtctgggtc acgtgccgct gtttggcgct tttgtgcgcg
       61 cccaggtctg ttggtgctca gagtgtggcc aggcggctcg gaccgagcag ggctttcctt
      121 gccagtggat tgtgtagagt atacagccag tctcttgtct tctgttcgac atggcatctt
      181 ctgatattca ggtgaaagag ctggagaagc gcgcttcagg ccaggctttt gagctgattc
      241 tcagccctcg gtcaaaagaa tctgtccccg atttccccct ttccccccca aagaagaagg
      301 acctttccct ggaggaaatc cagaagaaat tagaagctgc agaagaaaga cgcaagtctc
      361 atgaggcgga agtcttgaag cagctcgcgg agaagcggga gcatgagaag gaggtgctcc
      421 agaaagccat cgaggagaac aacaacttca gcaagatggc ggaggagaag ctgacccaca
      481 aaatggaggc taacaaagag aaccgggagg cgcagatggc ggccaagctg gagcgcttgc
      541 gagagaagga caagcacgtg gaagaggtgc ggaagaacaa agaatccaaa gaccccgcgg
      601 atgagactga ggctgactaa gttgtcccga gaactgactt tctccccgac cccgtcctaa
      661 atatccaaag actgtactgg ccagtgtcct ttactttccc tcctgacaga tagtctagaa
      721 gccgatgtag gaccgtatag gtagatccag accgtgagat gttttagggg ctcaagggga
      781 gaaactgaaa gtgttttact cttttttaaa gtgttggtct ttctaatgta gctatttttc
      841 tcgttgcatc ttttccactc gggcacaatc ggtgtgctgg gttaatggct agttctgtat
      901 tgactgtgga agatgtttgt gaagagtatg tggcggcttc ttccaaccca ttagatgctg
      961 aatatctgtc cactttgcga tcccaattct gtcccaatct caccagatgc tactgtactt
     1021 gaatggttaa taaactgcac agtgctgttg gtggcagtga aaaaaaaaaa
//
