LOCUS       NM_001379463            2160 bp    mRNA    linear   ROD 04-AUG-2024
DEFINITION  Mus musculus serine/threonine kinase-like domain containing 1
            (Stkld1), transcript variant 1, mRNA.
ACCESSION   NM_001379463 XM_006498115
VERSION     NM_001379463.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2160)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL773563.12.
            
            On Apr 3, 2020 this sequence version replaced XM_006498115.4.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189685.265863.1,
                                           SRR5189679.118791.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-57                AL773563.12        137587-137643
            58-144              AL773563.12        138845-138931
            145-189             AL773563.12        141512-141556
            190-264             AL773563.12        143502-143576
            265-369             AL773563.12        144542-144646
            370-440             AL773563.12        146662-146732
            441-556             AL773563.12        147408-147523
            557-675             AL773563.12        148973-149091
            676-839             AL773563.12        149295-149458
            840-970             AL773563.12        150128-150258
            971-1054            AL773563.12        150775-150858
            1055-1171           AL773563.12        152843-152959
            1172-1312           AL773563.12        153556-153696
            1313-1441           AL773563.12        154085-154213
            1442-1570           AL773563.12        154951-155079
            1571-1699           AL773563.12        155153-155281
            1700-1840           AL773563.12        156182-156322
            1841-1920           AL773563.12        156487-156566
            1921-2160           AL773563.12        156788-157027
FEATURES             Location/Qualifiers
     source          1..2160
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 19.12 cM"
     gene            1..2160
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /note="serine/threonine kinase-like domain containing 1"
                     /db_xref="GeneID:279029"
                     /db_xref="MGI:MGI:2685557"
     exon            1..57
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..2055
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /note="isoform 1 is encoded by transcript variant 1;
                     probable protein kinase-like protein SgK071 homolog;
                     likely ortholog of H. sapiens chromosome 9 open reading
                     frame 96 (C9orf96); sugen kinase 071; probable inactive
                     protein kinase-like protein SgK071 homolog;
                     serine/threonine kinase-like domain-containing protein 1;
                     serine/threonine kinase-like domain-containing protein
                     STKLD1"
                     /codon_start=1
                     /product="serine/threonine kinase-like domain-containing
                     protein STKLD1 isoform 1"
                     /protein_id="NP_001366392.1"
                     /db_xref="GeneID:279029"
                     /db_xref="MGI:MGI:2685557"
                     /translation="MEKYQLLQMLNPGALGVNLVVEELETETKFLIKQVECIDEHHAN
                     KALEELMPLLKLQHPNLSLYHEMFIMWNNEISSLFLCLVMDYYSQGTFQNIMENKRKL
                     KAVVDTEWMHTMLSQVLDAIEYLHKLNIVHRNLKPSNIVLVNSGYCKLQDMSSQALMT
                     HEAKWNVRAEEDPCQKSWMAPEALKFSFSTKSDIWSLGCIILDMATCSFLNDTEAMQL
                     RKAIRHHPGSLKPILKTMEEKQIPGTDVYYLLLPFMLHINPSDRLAIKDVMQVTFMSN
                     SFKSSSVALNMQRQKVPIFITDVLLEGNMANILDVMQNFSSRPEVQLRAINKLLTMPE
                     DQLGLPWPTELLEEVISIIKQHGRILDILLSTCSLLLRVLGQALAKDPEAEIPRSSLI
                     ISFLMDTLRSHPNSERLVNVVYNVLAIISSQGQISEELEEEGLFQLAQENLEHFQEDR
                     DICLSILSLLWSLLVDVVTVDKEPLEQLSGMVTWVLATHPEDVEIAEAGCAVLWLLSL
                     LGCIKESQFEQVVVLLLRSIQLCPGRVLLVNNAFRGLASLAKVSELVAFRIVVLEEGS
                     SGLHLIQDIYKLYKDDPEVVENLCMLLAHLTSYKEILPEMESGGIKDLVQVIRGRFTS
                     SLELISYADEILQVLEANAQPGLQEDQLEPPAGQEAPLQGEPLFRP"
     exon            58..144
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            145..189
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            190..264
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            265..369
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            370..440
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            441..556
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            557..675
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            676..839
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            840..970
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1054
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1171
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1312
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1441
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1570
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1699
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1840
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1841..1920
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     exon            1921..2160
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2131..2136
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /note="hexamer: AATAAA"
     polyA_site      2160
                     /gene="Stkld1"
                     /gene_synonym="Gm711; Sgk071"
                     /note="major polyA site"
ORIGIN      
        1 gcccggtagt aggacagtga ggcagtgtct ccacgagata ccatggaaaa atatcagcta
       61 ttgcaaatgc tgaatcctgg agccttaggg gtgaacctgg tggtggaaga actggaaact
      121 gaaaccaagt tcttgataaa gcaggtggag tgtattgatg agcaccatgc caacaaggcc
      181 ctggaggagc tgatgcccct gctgaagctc caacacccca atctctctct gtaccatgag
      241 atgttcatca tgtggaacaa tgagatctcc tctctgttcc tctgcctggt gatggattat
      301 tactcccaag gaacattcca gaatatcatg gagaataaga ggaagttaaa agcagttgtt
      361 gacactgagt ggatgcatac catgctaagc caggtattgg atgccatcga gtacctacat
      421 aagttgaaca tcgttcacag gaacctcaag ccttccaaca tcgtccttgt taacagtggc
      481 tactgtaaac tgcaggatat gagctcccag gcactgatga cccacgaagc taagtggaat
      541 gtccgagcag aagaagaccc ctgccagaag tcctggatgg ctcctgaagc tctcaaattc
      601 tccttctcca ccaaatccga catctggtct ctgggctgca tcattctaga catggccact
      661 tgctccttcc tgaacgacac agaagccatg caactgcgga aggccatccg ccatcatcca
      721 ggcagcctga agcccatcct gaaaaccatg gaggagaagc aaatccctgg tacagatgtc
      781 tactatttgc ttctgccctt catgttgcat atcaacccct ccgatcgact ggcaatcaag
      841 gatgtgatgc aagtcacctt catgagcaac tccttcaaaa gctcctctgt tgcgctgaat
      901 atgcagcggc agaaggtccc catcttcatc actgacgtgc tgcttgaagg caacatggcc
      961 aacatcttag atgtcatgca gaatttctcc agtcgaccag aggtccagct cagagccatt
     1021 aacaagttgt tgacaatgcc agaggaccag ctagggctgc catggcccac agagctgctg
     1081 gaagaggtga tcagcatcat aaagcagcat gggcggatcc tggatattct gctcagcacc
     1141 tgctcccttc tgctgcgtgt tcttggccaa gcactggcaa aggacccaga agctgagatc
     1201 ccaaggagca gtttgatcat ctccttcctg atggatacct tgcggagcca tcctaactct
     1261 gaaaggcttg ttaatgtggt ctacaacgtg cttgccatta tttccagcca aggacagatc
     1321 tcagaagagc tggaagagga ggggttgttt cagcttgccc aagagaacct ggagcacttc
     1381 caagaggaca gggacatctg cctctctatc ctgagcctgc tctggtccct cctggtagat
     1441 gttgtcactg tggacaaaga gcccttggag cagctctctg gcatggtcac ctgggtgctg
     1501 gctactcatc cggaggacgt ggaaatagca gaggctggct gtgcggtgct ctggctgctg
     1561 tccttgttgg gctgcataaa ggagagtcag tttgagcagg tggtagtgct gctcctgaga
     1621 agcatccagc tgtgccctgg cagagtactg ctggtgaaca atgcattccg tggcttggcc
     1681 agcctcgcaa aggtgtccga actggtggcc ttccgaatag tagtactgga agagggcagc
     1741 agcggcctcc acctcatcca agatatctac aagctctaca aggatgaccc tgaggtggtg
     1801 gagaacctct gcatgctgtt ggcccatctg acctcctaca aggagatcct gccagagatg
     1861 gagtctggag gcatcaaaga cctagtccag gtgatccggg ggcgctttac ctccagcctg
     1921 gagctgattt cttacgctga tgagatactc caggtactgg aagcaaatgc acaacctggc
     1981 ctccaggagg atcagcttga gcctcctgca gggcaggaag ccccactgca gggagagccc
     2041 ctcttcaggc cctgacatgc tgcccttctg gtcctgtggt aagagaaagt atcactaggt
     2101 ccagtattaa tttcgtaccc catggtgact aataaaagaa gccctaggct gtttctggca
//
