LOCUS       NM_175031               5221 bp    mRNA    linear   ROD 18-JUN-2024
DEFINITION  Mus musculus serine/threonine kinase 36 (Stk36), transcript variant
            1, mRNA.
ACCESSION   NM_175031 NM_172657
VERSION     NM_175031.4
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5221)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5221)
  AUTHORS   Roy,T.A., Bubier,J.A., Dickson,P.E., Wilcox,T.D., Ndukum,J.,
            Clark,J.W., Sukoff Rizzo,S.J., Crabbe,J.C., Denegre,J.M.,
            Svenson,K.L., Braun,R.E., Kumar,V., Murray,S.A., White,J.K.,
            Philip,V.M. and Chesler,E.J.
  TITLE     Discovery and validation of genes driving drug-intake and related
            behavioral traits in mice
  JOURNAL   Genes Brain Behav 23 (1), e12875 (2024)
   PUBMED   38164795
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   3  (bases 1 to 5221)
  AUTHORS   McCoy,C.J., Paupelin-Vaucelle,H., Gorilak,P., Beneke,T., Varga,V.
            and Gluenz,E.
  TITLE     ULK4 and Fused/STK36 interact to mediate assembly of a motile
            flagellum
  JOURNAL   Mol Biol Cell 34 (7), ar66 (2023)
   PUBMED   36989043
  REMARK    GeneRIF: ULK4 and Fused/STK36 interact to mediate assembly of a
            motile flagellum.
REFERENCE   4  (bases 1 to 5221)
  AUTHORS   Wang,B., Iyengar,R., Li-Harms,X., Joo,J.H., Wright,C., Lavado,A.,
            Horner,L., Yang,M., Guan,J.L., Frase,S., Green,D.R., Cao,X. and
            Kundu,M.
  TITLE     The autophagy-inducing kinases, ULK1 and ULK2, regulate axon
            guidance in the developing mouse forebrain via a noncanonical
            pathway
  JOURNAL   Autophagy 14 (5), 796-811 (2018)
   PUBMED   29099309
REFERENCE   5  (bases 1 to 5221)
  AUTHORS   Nozawa,Y.I., Yao,E., Gacayan,R., Xu,S.M. and Chuang,P.T.
  TITLE     Mammalian Fused is essential for sperm head shaping and
            periaxonemal structure formation during spermatogenesis
  JOURNAL   Dev Biol 388 (2), 170-180 (2014)
   PUBMED   24525297
REFERENCE   6  (bases 1 to 5221)
  AUTHORS   Merchant,M., Evangelista,M., Luoh,S.M., Frantz,G.D., Chalasani,S.,
            Carano,R.A., van Hoy,M., Ramirez,J., Ogasawara,A.K.,
            McFarland,L.M., Filvaroff,E.H., French,D.M. and de Sauvage,F.J.
  TITLE     Loss of the serine/threonine kinase fused results in postnatal
            growth defects and lethality due to progressive hydrocephalus
  JOURNAL   Mol Cell Biol 25 (16), 7054-7068 (2005)
   PUBMED   16055717
REFERENCE   7  (bases 1 to 5221)
  AUTHORS   Chen,M.H., Gao,N., Kawakami,T. and Chuang,P.T.
  TITLE     Mice deficient in the fused homolog do not exhibit phenotypes
            indicative of perturbed hedgehog signaling during embryonic
            development
  JOURNAL   Mol Cell Biol 25 (16), 7042-7053 (2005)
   PUBMED   16055716
REFERENCE   8  (bases 1 to 5221)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   9  (bases 1 to 5221)
  AUTHORS   Murone,M., Luoh,S.M., Stone,D., Li,W., Gurney,A., Armanini,M.,
            Grey,C., Rosenthal,A. and de Sauvage,F.J.
  TITLE     Gli regulation by the opposing activities of fused and suppressor
            of fused
  JOURNAL   Nat Cell Biol 2 (5), 310-312 (2000)
   PUBMED   10806483
REFERENCE   10 (bases 1 to 5221)
  AUTHORS   Carpenter,D., Stone,D.M., Brush,J., Ryan,A., Armanini,M.,
            Frantz,G., Rosenthal,A. and de Sauvage,F.J.
  TITLE     Characterization of two patched receptors for the vertebrate
            hedgehog protein family
  JOURNAL   Proc Natl Acad Sci U S A 95 (23), 13630-13634 (1998)
   PUBMED   9811851
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC117610.7.
            
            On Apr 8, 2022 this sequence version replaced NM_175031.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849384,
                              SAMN00849387 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               AC117610.7         154486-154630
            146-318             AC117610.7         155046-155218
            319-459             AC117610.7         156155-156295
            460-537             AC117610.7         156414-156491
            538-668             AC117610.7         158406-158536
            669-918             AC117610.7         162029-162278
            919-1012            AC117610.7         163789-163882
            1013-1182           AC117610.7         164106-164275
            1183-1370           AC117610.7         164418-164605
            1371-1470           AC117610.7         165703-165802
            1471-1614           AC117610.7         169593-169736
            1615-1794           AC117610.7         175213-175392
            1795-1892           AC117610.7         176302-176399
            1893-1998           AC117610.7         176847-176952
            1999-2149           AC117610.7         178510-178660
            2150-2277           AC117610.7         179030-179157
            2278-2382           AC117610.7         179560-179664
            2383-2481           AC117610.7         180412-180510
            2482-2570           AC117610.7         180602-180690
            2571-2634           AC117610.7         180935-180998
            2635-2745           AC117610.7         181159-181269
            2746-2826           AC117610.7         184603-184683
            2827-2998           AC117610.7         185746-185917
            2999-3146           AC117610.7         186159-186306
            3147-3294           AC117610.7         186524-186671
            3295-4041           AC117610.7         187027-187773
            4042-5221           AC117610.7         188732-189911
FEATURES             Location/Qualifiers
     source          1..5221
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 38.54 cM"
     gene            1..5221
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /note="serine/threonine kinase 36"
                     /db_xref="GeneID:269209"
                     /db_xref="MGI:MGI:1920831"
     exon            1..145
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            146..318
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     CDS             235..4185
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /EC_number="2.7.11.1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     serine/threonine-protein kinase 36; fused homolog;
                     serine/threonine kinase 36 (fused homolog, Drosophila)"
                     /codon_start=1
                     /product="serine/threonine-protein kinase 36 isoform 1"
                     /protein_id="NP_778196.2"
                     /db_xref="CCDS:CCDS35619.1"
                     /db_xref="GeneID:269209"
                     /db_xref="MGI:MGI:1920831"
                     /translation="MEKYHVLEMIGEGSFGRVYKGRKKYSAQVVALKFIPKLGRSEKE
                     LRNLQREIEIMRGLWHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQV
                     QAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSI
                     KGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYTTSIFQLVSLILKDPVR
                     WPSTISSCFKNFLQGLLTKDPRQRLSWPDLLHHPFIAGRVTIITEPAGSDLGTPFTSR
                     LPPELQVLKDEQAHRLAPKGNQSRILRQACKLMAEEAKQKEDQNAGSALEQEDGLCKV
                     TPSTAPVPGLKATPQESSLLAGILASEMKNNWEDWGAGEAPRTSRENHINLECEQGFP
                     EPRPEAMGRQSTDVVDPENEEPDSDDEWQRLLETSEPGPVQLKSPLTLLCNPDFCQRI
                     QSQLRGTGEQILKGVLDGVSHLLPVLRILSSLLSSCNDSVLLYSFCQEAGLPELPLSL
                     LRYSQESSSIQQQPWYGALLRDLVAVVQAYFSCTFNLERSQTGDSLQVFQEAASLFLD
                     LLGKLLAQSDDSEQTFRRDSLMCFAVLCEAVDGNSWAVSKAFYSSLLTTQRAVLDGLL
                     HGLTVPQLPFHTPPGAPQVSQPLREQSEDVPGAISSALAAMCTAPVGLPSCWDAKEQV
                     SWHLANQLTEDSSQLRPSLISGLRHHVLCLHLLKVLYACCYISERLCHILGQEPLALE
                     SLLMLVQGKVKVADWEESTEVALYLLSLLVFRLQDLPSGMEKLGSEVATLFTHSHVVS
                     LVNAAACLLGQLGQQGVTFDLQPREWIAAAAHALSAPAEVRLTPPYSCGFYDGLLILL
                     LQLLMQVQGKPGLIRDVVGSEVWTILWHRFSMALRLPEEVSAQEDDLLLSSPSSLEPD
                     WTLISPQGMAALLSLAMAIFTQESQLCLSHLSQHGSVLMLTLKHLLSPSFLHHLSQAP
                     QGPEFLPVVVLSVCKLLCFPFALDVDADLLVGVLADLRASEVVVCLLQVCCHHLSLLQ
                     AELPIGLLTRLALTDSASLKQFVNTVATSSRAIISFLSVVLLSDQPLMISDLLSLLTH
                     TARILSPSHLSFIQELLSGSDESYRPLRSLLGHSENTVRVRAYGLLGHLLQHSMALRG
                     ALQSQSGLLNLLLLGLGDKDPAVRRSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGD
                     AQDGIRRNAASALGNLGPEGLGKELLKCQVPQRLLEMACGDPQPTVKEAALIALRSLQ
                     QESCIHQVLVSLGASEKLALLSLGNQLLPNSSNRPASVRHCRKLIQLLRPTHST"
     exon            319..459
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            460..537
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            538..668
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            669..918
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1012
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1182
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1370
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1470
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1614
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1794
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1892
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..1998
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2149
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2150..2277
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2278..2382
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2383..2481
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2482..2570
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2571..2634
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2635..2745
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2746..2826
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2827..2998
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            2999..3146
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            3147..3294
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            3295..4041
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     exon            4042..5221
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4349..4354
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /note="hexamer: ATTAAA"
     polyA_site      4370
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /note="major polyA site"
     regulatory      5199..5204
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /note="hexamer: ATTAAA"
     polyA_site      5221
                     /gene="Stk36"
                     /gene_synonym="1700112N14Rik; B930045J24; FU; Fused;
                     mKIAA1278"
                     /note="major polyA site"
ORIGIN      
        1 aactgaagac tctagatcct ttgtggggcc tgctagccaa gcgacagaag tgccctacaa
       61 agtgccaatg ggcggttcgc atctgtcaca cacctctgag agctttgtcc tttaaacttc
      121 taatcagttc cagggagtaa aactggcctc ccagatgtgt ggaactaccc ctggatctat
      181 agctctttgt caccgtcttc tttctacctt ctgagagacc ccgaaaccct tgccatggaa
      241 aagtaccacg ttttggagat gattggagaa ggctcttttg ggagagtgta taagggccga
      301 aaaaaataca gtgctcaggt ggtggccttg aagttcatcc ccaaactggg gcgctcagag
      361 aaagagctga ggaatctgca acgagagatt gaaatcatgc ggggtctgtg gcatcccaac
      421 attgtgcata tgctcgacag ctttgagact gacaaagagg tggtggtggt gacagactac
      481 gctgaaggag aactctttca gattctggaa gatgatggaa aacttcctga agaccaggtt
      541 caggccatcg ctgcccagtt ggtgtcagct ctgtactacc tgcattccca ccgcatccta
      601 caccgcgaca tgaaaccgca gaacattctt ctcgccaagg gtggtggcat taaactttgt
      661 gactttggat tcgcccgagc tatgagcacc aacaccatgg tgctgacgtc gatcaaaggc
      721 acaccgctct atatgtctcc agagctggtg gaggagcgac catatgacca caccgcagac
      781 ctctggtctg tgggctgcat cctgtatgag ctggctgtcg gcacgcctcc cttctacacc
      841 accagcatct ttcagctggt tagcctcatt ctcaaggacc ctgtgcgctg gccctccacc
      901 attagttcct gcttcaagaa cttcttgcag gggctgctca ccaaggaccc ccggcagcgt
      961 ctgtcctggc cagacctctt acatcacccc tttattgccg gccgtgtcac catcataact
     1021 gaaccagcag gctccgattt gggcacccca tttactagtc gcctaccccc agaacttcag
     1081 gtcctcaagg atgaacaggc gcatcggctc gcacccaagg gtaaccagtc tcgcatcctg
     1141 cgccaggcct gtaaactcat ggctgaagaa gccaagcaga aggaagacca aaatgcagga
     1201 tctgcccttg aacaagaaga cgggctctgc aaggtgacac ccagcacagc ccccgtgcct
     1261 ggactaaagg ccactcctca ggagtcaagc ctcttggctg gtatactggc ttcagaaatg
     1321 aagaacaact gggaagactg gggggctgga gaagcacccc gtacctctcg ggaaaaccac
     1381 atcaacctgg agtgtgaaca aggcttccca gagccgaggc cagaggcgat gggccggcag
     1441 agcactgatg tagtggatcc tgaaaatgag gagccagaca gtgatgatga gtggcaacgc
     1501 ctactagaga ccagcgagcc tgggcctgtg cagctgaagt cccccctcac cctgttgtgt
     1561 aaccctgact tctgccagcg catccagagt cagctgcgcg ggactggcga gcagatcctg
     1621 aaaggcgttc tggatggtgt gtcccacctc cttcctgtac tccgcatcct gagtagtctc
     1681 ctatccagct gcaatgactc tgtgctcttg tattccttct gccaggaggc aggactgcct
     1741 gagctgcctc tcagccttct taggtacagc caggagagta gcagcatcca gcagcaacct
     1801 tggtatgggg cgctcttacg ggacctggtg gctgtggttc aggcctactt ttcgtgcacc
     1861 ttcaatctgg agaggagcca gacaggtgac agcctacagg tgtttcagga ggccgccagc
     1921 ctctttttgg acctgttggg gaagctgctg gcccaatcag atgattccga gcagacattt
     1981 cgaagggata gccttatgtg ctttgctgtc ttgtgtgaag ctgtggacgg aaacagctgg
     2041 gccgtctcca aagccttcta ctccagcctg ttgaccacac agcgcgctgt gttggatggc
     2101 ctccttcacg gcctgacagt cccacagctt cctttccaca caccaccagg agccccacaa
     2161 gtgagccagc cgctgcggga gcagagtgaa gatgtacctg gagccatctc ttctgccctg
     2221 gcagccatgt gtactgctcc tgtggggctg cccagctgtt gggatgccaa ggagcaggtc
     2281 tcttggcatt tggccaacca gctaactgaa gacagcagcc aactgaggcc atccctcatc
     2341 tctggtctgc gacaccatgt cctgtgcctc caccttctca aggttctcta cgcctgctgc
     2401 tatattagtg agcgcctgtg ccatattctg gggcaagagc ccctggcctt ggagtcgctg
     2461 ctgatgttag tccagggcaa ggtgaaagta gcagattggg aagagtccac tgaggtggca
     2521 ctttacctcc tgtcccttct tgtctttcgg ctccaagatc tgccttcagg gatggagaag
     2581 ctgggcagtg aggttgctac tctctttacc cactcacatg tcgtctctct tgtgaatgcg
     2641 gcagcctgtc tcttaggaca gcttggtcag caaggggtga cctttgacct ccagccccgg
     2701 gaatggattg ctgcagctgc acatgccttg tctgcccctg cagaggtccg gctgactccg
     2761 ccgtatagtt gtggcttcta tgatggcctc ctcattctcc tgcttcagct tcttatgcag
     2821 gtacagggga agcctggcct gatcagggat gtggttggtt cagaggtgtg gaccattctg
     2881 tggcaccgct tttccatggc cctgaggctg cccgaggagg tgtctgccca ggaagacgac
     2941 ctgctactat caagtccctc cagcctagag ccagactgga cactgatttc accccaaggc
     3001 atggcagcct tgctgagcct ggccatggcc atcttcaccc aggagtccca gttatgcctg
     3061 agccacctgt cccagcatgg cagtgtcctc atgctgaccc tgaagcacct gctttcaccc
     3121 agcttcttgc accacctgag ccaggcgccg caggggcccg agtttctccc cgttgtggtg
     3181 ctctccgtgt gcaagctgct ctgcttccct tttgccctgg atgtggatgc tgacctcctt
     3241 gtaggtgtct tggctgacct cagggcctcg gaagtggtag tctgcctgct gcaggtctgc
     3301 tgccaccacc tttcgttgtt acaagcagag ctgcccattg gcctccttac acgcctggcc
     3361 ctcacggatt ctgcctctct caagcagttt gtgaacacag tggccacctc ttctagagcc
     3421 atcatctcat tcctctctgt tgttctcctg agtgaccagc ccctcatgat ctctgacctc
     3481 ctgtccctgc tgacacacac agcccggatt ctgtccccca gccacttgtc ctttatccaa
     3541 gagctcctgt ctggctctga tgaatcctat cggccattgc gcagcctcct aggccactca
     3601 gagaacactg tgcgggtccg tgcatatggg ctcctgggac atttattaca gcacagcatg
     3661 gccctacgtg gggcactaca gagtcagtca ggactgctca accttctgct gctagggctt
     3721 ggagacaagg accctgccgt gcgacgcagt gccagctttg ctgtgggcaa tgcagcctac
     3781 caggctgggc ctttgggacc tgccttggca gctgcagtgc ccagtatgac ccagctgctt
     3841 ggagatgctc aggatgggat ccggcgcaat gctgcatcag ctctaggcaa tctgggacct
     3901 gaaggattgg gcaaggagct attaaagtgc caagtacccc agcggctcct agaaatggca
     3961 tgtggagacc ctcagccaac tgtcaaagag gctgccctca ttgcccttcg aagcctccaa
     4021 caggagtcct gtattcatca ggtgctggtg tcgctgggtg ccagtgagaa gttagccttg
     4081 ctctctttgg ggaatcagtt actgccgaat agcagcaaca ggcctgcctc cgtcagacac
     4141 tgcaggaagc tcatccaact cctgaggcca acccacagca catgagcccg cactcctggg
     4201 gttacctcca gccttcactg tcctactgtt gccaagattt ccttattctc ctacccaagc
     4261 tactaactca gccaagagct gatgagactg agaaagagtg ctgagctgcc aactcccctc
     4321 caagtgagaa actagaagag attttcttat taaagcttcc tttccctaga cttatgatga
     4381 cttgaatcag taaacttcat cactgttggt gccagagaaa atcccttcct ctctacacgt
     4441 agggatcttt cctccagtaa tgggccctca accccaggac catgccatcc acccaggcct
     4501 taagggaaaa aactacctct gccttactgg ctctcctgta atctgcccgg ctacttttgc
     4561 cttaagtaca ctactgacct ctgtttcagc tctgccccat ggggataaat gtcattaccc
     4621 ctattgttga ggggttcctc agctcgtagc ctacctgaag ctcccaaggt aaggggtggg
     4681 aagcttgggc ccttttctag cttctctgac accggaagcc ctgtaccctg ttcacacaag
     4741 atcctggttt agagaattgt ttataccttt caaggaaagg ccagtggagc taatacagac
     4801 acgactgggg ctaaacagag gtaaagcaag gtgctttgag ataatacagt cattttagta
     4861 tttaatgcag tgtcaatgga tatggaaccc tagctgcttt gaaaatttat ggagactggc
     4921 gtttaccaga aaaaagtgtt tgactgtccc attagttaga ctcgaatgta accagtttac
     4981 ctgaaaggtc gttgggcaga cacattagaa tctaactgca tgtgtattag gaagcttgac
     5041 tgagataagc ttccaggtcc ccgatttctc catccagtaa aaggagaggc tcctcttggt
     5101 accgctcagc gatcagtgct tgctcctagg tatggggtgc tcgggttcag tccccagctg
     5161 atgggagggg gagaaaggtg cctttctgtc cttccttaat taaaggtttt aagaaatgaa
     5221 a
//
