LOCUS       NM_022416               3446 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus serine/threonine kinase 32B (Stk32b), mRNA.
ACCESSION   NM_022416 XM_972948 XM_972984 XM_973025
VERSION     NM_022416.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3446)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3446)
  AUTHORS   Rattner,A., Terrillion,C.E., Jou,C., Kleven,T., Hu,S.F.,
            Williams,J., Hou,Z., Aggarwal,M., Mori,S., Shin,G., Goff,L.A.,
            Witter,M.P., Pletnikov,M., Fenton,A.A. and Nathans,J.
  TITLE     Developmental, cellular, and behavioral phenotypes in a mouse model
            of congenital hypoplasia of the dentate gyrus
  JOURNAL   Elife 9, e62766 (2020)
   PUBMED   33084572
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3446)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   4  (bases 1 to 3446)
  AUTHORS   Ruiz-Perez,V.L., Ide,S.E., Strom,T.M., Lorenz,B., Wilson,D.,
            Woods,K., King,L., Francomano,C., Freisinger,P., Spranger,S.,
            Marino,B., Dallapiccola,B., Wright,M., Meitinger,T.,
            Polymeropoulos,M.H. and Goodship,J.
  TITLE     Mutations in a new gene in Ellis-van Creveld syndrome and Weyers
            acrodental dysostosis
  JOURNAL   Nat Genet 24 (3), 283-286 (2000)
   PUBMED   10700184
  REMARK    Erratum:[Nat Genet 2000 May;25(1):125]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158588.3, AC110244.10 and AC110565.7.
            
            On Oct 3, 2022 this sequence version replaced NM_022416.2.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056396.1, AK082468.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-425               AC158588.3         155172-155596       c
            426-481             AC158588.3         87528-87583         c
            482-633             AC110244.10        205008-205159       c
            634-807             AC110244.10        107694-107867       c
            808-845             AC110244.10        75138-75175         c
            846-935             AC110244.10        66610-66699         c
            936-1039            AC110565.7         177140-177243       c
            1040-1156           AC110565.7         171754-171870       c
            1157-1282           AC110565.7         170006-170131       c
            1283-1414           AC110565.7         167526-167657       c
            1415-1479           AC110565.7         165339-165403       c
            1480-3446           AC110565.7         157229-159195       c
FEATURES             Location/Qualifiers
     source          1..3446
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 20.18 cM"
     gene            1..3446
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /note="serine/threonine kinase 32B"
                     /db_xref="GeneID:64293"
                     /db_xref="MGI:MGI:1927552"
     exon            1..425
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     CDS             374..1618
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /EC_number="2.7.11.1"
                     /note="serine threonine kinase 32"
                     /codon_start=1
                     /product="serine/threonine-protein kinase 32B"
                     /protein_id="NP_071861.1"
                     /db_xref="CCDS:CCDS39076.1"
                     /db_xref="GeneID:64293"
                     /db_xref="MGI:MGI:1927552"
                     /translation="MGGNHSHKPPVFDENEEVNFDHFQILRAIGKGSFGKVCIVQKRD
                     TKKMYAMKYMNKQKCVERDEVRNVFRELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDL
                     LLGGDLRYHLQQNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHV
                     HITDFNIATVLKGSEKASSMAGTKPYMAPEVFQVYVDGGPGYSYPVDWWSLGVTAYEL
                     LRGWRPYEIHSATPIDEILNMFKVERVHYSSTWCEGMVSLLKKLLTKDPESRLSSLRD
                     IQSMTYLADMNWDAVFEKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAK
                     HRSRDSTKDSCPLNGHLQQCLETVRKEFIIFNREKLRRQQGHNGQLSDLDGRIGSQTS
                     SKLQDGRNNNILTHTCPRGCSS"
     exon            426..481
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            482..633
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            634..807
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            808..845
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            846..935
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1039
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1156
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1282
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1414
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1479
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..3446
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3429..3434
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /note="hexamer: AATAAA"
     polyA_site      3446
                     /gene="Stk32b"
                     /gene_synonym="2510009F08Rik; Stk32; STKG6; YANK2"
                     /note="major polyA site"
ORIGIN      
        1 ctcctccttt ttcctcacca ccgttgtgag cagagctgca cggtggtctg ggctcaggga
       61 gtccccgggt ttccatccgt gtattgtgcg tcatggagag aatcgggtga gggctcaggg
      121 ggtgcggtga tcgcagcggg gtgacaccct ggaggagggg tgaccacacg gtccccatcc
      181 ctgccctgca atcggccccc tccacacacg ctacaaccct ggctggctgc tctcacccag
      241 gctgcatccc agggctctca tcctgcacac tgcatcccaa gagcatcctg gatcccgtat
      301 cgctgtgaga atcctgcatc tgacatcccg aaaggagagg ccgggcatgt agtagcggca
      361 gtagcggcgg aatatgggcg ggaaccactc ccacaagccc ccagtgtttg atgagaacga
      421 agaagtcaac tttgaccact tccagatcct gcgggccatt gggaaaggaa gttttggaaa
      481 ggtatgcatc gtgcagaagc gagacacaaa gaagatgtat gccatgaagt acatgaacaa
      541 gcaaaagtgt gtggagaggg atgaggtgcg gaacgtgttc cgggagctgc agatcatgca
      601 gggattagag caccccttcc tggtgaacct atggtactcc ttccaggatg aggaagacat
      661 gttcatggtg gtggacctgc tgctgggtgg ggacctgcgc taccacctac agcagaatgt
      721 gcacttcaca gaggggaccg tgaagctgta catctgtgag ctggccctgg ctctggagta
      781 cctgcagagg taccacatca tccacagaga catcaagcca gacaacatcc tactggatga
      841 gcatgggcac gtgcacataa cggacttcaa catcgccacg gtcctgaaag gaagtgagaa
      901 ggcttcctcc atggctggca cgaagcccta catggcccct gaagtcttcc aggtgtatgt
      961 ggatggaggc cctgggtact cataccccgt ggactggtgg tcactgggtg tcacagccta
     1021 tgagctgctc cgaggctgga ggccatatga gatccactca gccacaccca ttgatgagat
     1081 tctcaacatg ttcaaggtgg agcgtgtcca ctactcctcc acgtggtgtg aggggatggt
     1141 gtccctgctg aagaagctgc tgaccaagga ccctgagagc cgcttgtcaa gtcttcgtga
     1201 catccagagc atgacctacc tggctgacat gaactgggat gcagtattcg agaaggccct
     1261 gatgcctggc tttgtgccca ataaagggag actgaactgt gaccccacat ttgaacttga
     1321 agaaatgatt ctagaatcca agccacttca caaaaagaag aagaggttgg ccaagcatag
     1381 gtccagagac agcacaaagg acagctgtcc cctgaatgga cacctgcagc agtgtttgga
     1441 gacagtgcgg aaagagttca tcatattcaa ccgagagaaa ctcaggaggc agcagggaca
     1501 taatggccaa ctctcagacc tggatggccg aataggaagc cagacctcaa gcaagctgca
     1561 ggatggtcga aacaataaca tcctgaccca tacatgcccc cgaggctgca gcagctaaac
     1621 tcgactgccc agatgacact gtctgccctg acacccagaa cccccctgtc ccctgatgga
     1681 ccccatctca cccctaaaac atcagatgca ggaagagctc tgtattcagg gttctggtcc
     1741 ttgtttccag ctgattcgct gtgtgacctt gagcaaatca cacattctct gtgcctcagt
     1801 tttctgcatc tgtggaaggg gttaaacagc tctttgcccc atctccagtc ataaaattgt
     1861 gagaatctgg ttggactgca gatatgtaaa ctcctgggca ttgatcaagt gtttatacat
     1921 gtaaattatc tcaatatcta aagtgtcctc cctagccccc acacaatttt aaccatgaga
     1981 actttgcaat ttggcccatc ctagtttgct tgatggaact ttcaacaaca taaatagctg
     2041 atatgtttgt ccctcttatg ggacttccag gttccaaagc aaccaggaag agtcacacac
     2101 agacttcctg gccttctgga atggtgcagc ataaagacca agcccaggag tttctgctgc
     2161 aaacaggttt ttccctgact cgtggaaggc tgcccccaca tttggattcc agcaatcacc
     2221 agctatcacc atatccccac atccccgtgt tagatggcac tgtgtctctg gccactcctc
     2281 cccaccacag agtgtcctgg gatcccagag gagactcatc ctgcagcgtg acctcagtcc
     2341 ccaccaggaa gaatataaga gtccagtcag cctgtcatgc aaaggctccc tggctgggta
     2401 gtcagagctt cctgttgata ccttaggaag cctcggtgct tagagtcttc tgtagacaca
     2461 agcagaatca ctcaagaagc caagtatctt ataccctggc caggaaccag ctgacccttg
     2521 agctgaggat gctgagatta gcaaagaaag ccagttggca gctgcagcca agactggaag
     2581 acctctgcaa atcatgtgct tgctcaaagg tcaattttct cattctcaaa aaaggaagga
     2641 gaaggatggc cttgttatgg gacttgataa gatcccatgt gtcacacagt gatgactgac
     2701 gttggccatc accctcctca tcatcatctc cctcctcttc ctcctcctcc tcctcatctc
     2761 cctcctcttc ttcttcctcc tcctcctcct catctccctc ctcttcttct tcctcctctt
     2821 cctcctccct cttctctacc ctccccctac tcttcctcct cctcatattt atcatcatca
     2881 ccaccatcat gactgcaatc ctcctctgtt ggaggtactt tcctgttttg gtgacatagc
     2941 aggtctgatt tctgtggacc aaggatcctc caagtttaca gtttgttttc ttttcttacc
     3001 tggagcctct gaggtctgga catccccgct aagaacatcc ctactgagat caagtgtttt
     3061 cacgtcagcc tctgtttcca ttttccactt tctcactatg attcacgtct atcagtgtca
     3121 tctcttagat ctcttgagag acattttaat gtatggtaag gttttacact tttcaaataa
     3181 ctgcattgta ccaccccctt aactgagtcc ccccaccatg tctatctcct gcccactgta
     3241 ctgtctccag cccctgtctg cccttcctgc cctgcagaac atccagccga tcttctctac
     3301 actgtgacct agaagtatca taatgtcttc ttggcatgag cttgtgaatg agaggaggtg
     3361 gtgaagggga ggtgcacggt ggggaccctg attatttggc tctgtttaag tccatgttcc
     3421 ttgttcagaa taaataagca ctcaga
//
