LOCUS       NM_019442               1078 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus serine/threonine kinase 19 (Stk19), mRNA.
ACCESSION   NM_019442
VERSION     NM_019442.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1078)
  AUTHORS   Xie,T., Rowen,L., Aguado,B., Ahearn,M.E., Madan,A., Qin,S.,
            Campbell,R.D. and Hood,L.
  TITLE     Analysis of the gene-dense major histocompatibility complex class
            III region and its comparison to mouse
  JOURNAL   Genome Res 13 (12), 2621-2636 (2003)
   PUBMED   14656967
REFERENCE   2  (bases 1 to 1078)
  AUTHORS   Allcock,R.J., Martin,A.M. and Price,P.
  TITLE     The mouse as a model for the effects of MHC genes on human disease
  JOURNAL   Immunol Today 21 (7), 328-332 (2000)
   PUBMED   10871872
  REMARK    Review article
REFERENCE   3  (bases 1 to 1078)
  AUTHORS   Yang,Z. and Yu,C.Y.
  TITLE     Organizations and gene duplications of the human and mouse MHC
            complement gene clusters
  JOURNAL   Exp Clin Immunogenet 17 (1), 1-17 (2000)
   PUBMED   10686478
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CT573030.3.
            
            On Nov 17, 2006 this sequence version replaced NM_019442.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC022681.1, AK168865.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164142
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-127               CT573030.3         198774-198900       c
            128-264             CT573030.3         198427-198563       c
            265-360             CT573030.3         194443-194538       c
            361-500             CT573030.3         194010-194149       c
            501-598             CT573030.3         186748-186845       c
            599-746             CT573030.3         186511-186658       c
            747-1078            CT573030.3         185990-186321       c
FEATURES             Location/Qualifiers
     source          1..1078
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 18.38 cM"
     gene            1..1078
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /note="serine/threonine kinase 19"
                     /db_xref="GeneID:54402"
                     /db_xref="MGI:MGI:1860085"
     exon            1..127
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..792
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /EC_number="2.7.11.1"
                     /note="serine/threonine-protein kinase 19"
                     /codon_start=1
                     /product="inactive serine/threonine-protein kinase 19"
                     /protein_id="NP_062315.1"
                     /db_xref="CCDS:CCDS28659.1"
                     /db_xref="GeneID:54402"
                     /db_xref="MGI:MGI:1860085"
                     /translation="MNRKRRLLASEAFGVKRRRAPGPVRADPLRTRAGSAREAIEELV
                     KLFPRGLFEDALPPIALRSQVYSLVPDRTVADLQLKELQELGEIRIIQLGFDLDAHGI
                     VFTEDYRTRVLKACDGRPCAGAVQKFLASVLPACGDLSFQQDQMTQTYGFRDPEITQL
                     VNAGVLTVRDAGSWWLAVPGAGRFIKCFVKGRQAVLSMVRKAKYRELALSELLGRRAP
                     LAVRLGLAYHVHDLIGAQLVDCVPTTSGTLLRLPDT"
     exon            128..264
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /inference="alignment:Splign:2.1.0"
     exon            265..360
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /inference="alignment:Splign:2.1.0"
     exon            361..500
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /inference="alignment:Splign:2.1.0"
     exon            501..598
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /inference="alignment:Splign:2.1.0"
     exon            599..746
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /inference="alignment:Splign:2.1.0"
     exon            747..1078
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1058..1063
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /note="hexamer: AATAAA"
     polyA_site      1078
                     /gene="Stk19"
                     /gene_synonym="G11; RP1"
                     /note="major polyA site"
ORIGIN      
        1 ctttcccgga atcctgaaat ccgggttatg aatcgcaaga gacggctcct ggcgtctgag
       61 gcttttgggg tgaagcggag gcgggcgccg gggcccgtga gagcggatcc tttaagaaca
      121 agagcaggct cggcgcgcga ggccatcgag gagctcgtga agctgtttcc ccgggggctg
      181 ttcgaggatg cgctgccgcc catcgcgctg aggagccaag tgtacagtct ggtgccagac
      241 cggacggtgg ccgacctaca actgaaggag cttcaagagc tgggagagat ccgaattatc
      301 cagctaggct ttgacttgga tgctcatggg attgtcttca cggaagacta caggacccgg
      361 gtcctcaagg cctgtgatgg ccgaccatgt gctggggcgg tgcagaagtt cctggcctca
      421 gtgctcccag cctgtgggga cctcagtttc cagcaggatc agatgacaca gacttatggc
      481 ttcagggacc cggagatcac gcagctggtg aacgctgggg tcctcactgt ccgagatgct
      541 ggaagctggt ggctggctgt gcctggagct gggagattca tcaagtgctt tgttaaaggg
      601 cgccaggctg tactgagcat ggtgcggaag gccaagtacc gggagcttgc cttgtcagag
      661 ctcctgggcc gcagggcccc tttggcagtg cggctaggtc ttgcctacca tgtgcacgac
      721 ctcattggag cccagctggt ggactgtgtc cccaccactt ctggaaccct ccttcgcctg
      781 ccagatacat gaggagccaa tgcttggatt ctgcaactca ctgagtgagg ttcctggaag
      841 tgccacccca gggtggctga gcaagtcacc gcagtgggtg ccaggctctg ctgctgcaag
      901 ctgggcttct acctgagctg ggctgtgggc attgcagctc ttgcttctgt gcgtgtggag
      961 tcaggagccg tgccaagggg atgagaaggt ggggttgctg gagacactgg agcagggagt
     1021 agaaaactct gcccttcacg tcaggctgaa attgccaaat aaaatacttg tgcctgta
//
