LOCUS       NM_025288                412 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus stefin A3 (Stfa3), mRNA.
ACCESSION   NM_025288
VERSION     NM_025288.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Mezzapesa,A., Bastelica,D., Crescence,L., Poggi,M., Grino,M.,
            Peiretti,F., Panicot-Dubois,L., Dupont,A., Valero,R.,
            Maraninchi,M., Bordet,J.C., Alessi,M.C., Dubois,C. and Canault,M.
  TITLE     Increased levels of the megakaryocyte and platelet expressed
            cysteine proteases stefin A and cystatin A prevent thrombosis
  JOURNAL   Sci Rep 9 (1), 9631 (2019)
   PUBMED   31270351
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  AUTHORS   Rauch,F., Geng,Y., Lamplugh,L., Hekmatnejad,B., Gaumond,M.H.,
            Penney,J., Yamanaka,Y. and Moffatt,P.
  TITLE     Crispr-Cas9 engineered osteogenesis imperfecta type V leads to
            severe skeletal deformities and perinatal lethality in mice
  JOURNAL   Bone 107, 131-142 (2018)
   PUBMED   29174564
REFERENCE   3  (bases 1 to 412)
  AUTHORS   Hosoi,T., Suzuki,S., Okuma,Y., Kawakami,A., Ogawa,N., Ozawa,K. and
            Nomura,Y.
  TITLE     LPS induces stefin A3 expression in mouse primary cultured glial
            cells
  JOURNAL   Brain Res Mol Brain Res 140 (1-2), 138-141 (2005)
   PUBMED   16143425
  REMARK    GeneRIF: Stefin A3 is involved in infection and inflammation in
            primary cultured glial cells.
REFERENCE   4  (bases 1 to 412)
  AUTHORS   Roper,R.J., McAllister,R.D., Biggins,J.E., Michael,S.D., Min,S.H.,
            Tung,K.S., Call,S.B., Gao,J. and Teuscher,C.
  TITLE     Aod1 controlling day 3 thymectomy-induced autoimmune ovarian
            dysgenesis in mice encompasses two linked quantitative trait loci
            with opposing allelic effects on disease susceptibility
  JOURNAL   J Immunol 170 (12), 5886-5891 (2003)
   PUBMED   12794114
REFERENCE   5  (bases 1 to 412)
  AUTHORS   Tsui,F.W., Tsui,H.W., Mok,S., Mlinaric,I., Copeland,N.G.,
            Gilbert,D.J., Jenkins,N.A. and Siminovitch,K.A.
  TITLE     Molecular characterization and mapping of murine genes encoding
            three members of the stefin family of cysteine proteinase
            inhibitors
  JOURNAL   Genomics 15 (3), 507-514 (1993)
   PUBMED   8468045
REFERENCE   6  (bases 1 to 412)
  AUTHORS   Noebels,J.L., Qiao,X., Bronson,R.T., Spencer,C. and Davisson,M.T.
  TITLE     Stargazer: a new neurological mutant on chromosome 15 in the mouse
            with prolonged cortical seizures
  JOURNAL   Epilepsy Res 7 (2), 129-135 (1990)
   PUBMED   2289471
  REMARK    Erratum:[Epilepsy Res 1992 Mar;11(1):72]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK014349.1.
            
            On Apr 6, 2007 this sequence version replaced NM_025288.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK014349.1, BB747166.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-412               AK014349.1         4-415
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 25.55 cM"
     gene            1..412
                     /gene="Stfa3"
                     /gene_synonym="Stf3"
                     /note="stefin A3"
                     /db_xref="GeneID:20863"
                     /db_xref="MGI:MGI:106196"
     exon            1..112
                     /gene="Stfa3"
                     /gene_synonym="Stf3"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..340
                     /gene="Stfa3"
                     /gene_synonym="Stf3"
                     /codon_start=1
                     /product="stefin-3"
                     /protein_id="NP_079564.1"
                     /db_xref="CCDS:CCDS28153.1"
                     /db_xref="GeneID:20863"
                     /db_xref="MGI:MGI:106196"
                     /translation="MSQENLKIKGGLSEARPATPEIQMIADKVRPLLEEQTNEKYEKF
                     EAVEYKSQVVAGQNLFIKIDVGNGCFLHMKVFRGLSGEDDLKLKGYQTNKTKTDELTS
                     M"
     exon            113..214
                     /gene="Stfa3"
                     /gene_synonym="Stf3"
                     /inference="alignment:Splign:2.1.0"
     exon            215..412
                     /gene="Stfa3"
                     /gene_synonym="Stf3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      395..400
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stfa3"
                     /gene_synonym="Stf3"
                     /note="hexamer: AATAAA"
     polyA_site      411
                     /gene="Stfa3"
                     /gene_synonym="Stf3"
                     /note="major polyA site"
ORIGIN      
        1 tcatttcttc tcagcaccct gcccatcaat gagtcaagaa aacttaaaaa taaagggagg
       61 cctgtcagag gccagacctg ccacaccaga aatccagatg attgctgaca aggtcagacc
      121 tctgcttgaa gagcaaacca atgagaaata tgaaaaattc gaggctgtcg agtataaatc
      181 tcaagtcgtt gctggacaaa atttgttcat taagatagat gtagggaatg gttgtttcct
      241 tcacatgaaa gtcttcagag gcctttctgg agaagatgat ttgaaactta agggttacca
      301 gactaacaaa accaagactg atgagctgac ctccatgtaa gcagccaatt ctaaagtgac
      361 ctgattcttc tccttgtaaa gagatgcagc cgtcaataaa gaagcattgt tc
//
