LOCUS       NM_001082545             423 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus stefin A2 (Stfa2), mRNA.
ACCESSION   NM_001082545 XM_001001640 XM_001002259 XM_001002270 XM_001002402
            XM_148531 XM_915403
VERSION     NM_001082545.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Mezzapesa,A., Bastelica,D., Crescence,L., Poggi,M., Grino,M.,
            Peiretti,F., Panicot-Dubois,L., Dupont,A., Valero,R.,
            Maraninchi,M., Bordet,J.C., Alessi,M.C., Dubois,C. and Canault,M.
  TITLE     Increased levels of the megakaryocyte and platelet expressed
            cysteine proteases stefin A and cystatin A prevent thrombosis
  JOURNAL   Sci Rep 9 (1), 9631 (2019)
   PUBMED   31270351
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 423)
  AUTHORS   Mihelic,M., Teuscher,C., Turk,V. and Turk,D.
  TITLE     Mouse stefins A1 and A2 (Stfa1 and Stfa2) differentiate between
            papain-like endo- and exopeptidases
  JOURNAL   FEBS Lett 580 (17), 4195-4199 (2006)
   PUBMED   16831429
REFERENCE   4  (bases 1 to 423)
  AUTHORS   Roper,R.J., McAllister,R.D., Biggins,J.E., Michael,S.D., Min,S.H.,
            Tung,K.S., Call,S.B., Gao,J. and Teuscher,C.
  TITLE     Aod1 controlling day 3 thymectomy-induced autoimmune ovarian
            dysgenesis in mice encompasses two linked quantitative trait loci
            with opposing allelic effects on disease susceptibility
  JOURNAL   J Immunol 170 (12), 5886-5891 (2003)
   PUBMED   12794114
REFERENCE   5  (bases 1 to 423)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   6  (bases 1 to 423)
  AUTHORS   Tsui,F.W., Tsui,H.W., Mok,S., Mlinaric,I., Copeland,N.G.,
            Gilbert,D.J., Jenkins,N.A. and Siminovitch,K.A.
  TITLE     Molecular characterization and mapping of murine genes encoding
            three members of the stefin family of cysteine proteinase
            inhibitors
  JOURNAL   Genomics 15 (3), 507-514 (1993)
   PUBMED   8468045
REFERENCE   7  (bases 1 to 423)
  AUTHORS   Noebels,J.L., Qiao,X., Bronson,R.T., Spencer,C. and Davisson,M.T.
  TITLE     Stargazer: a new neurological mutant on chromosome 15 in the mouse
            with prolonged cortical seizures
  JOURNAL   Epilepsy Res 7 (2), 129-135 (1990)
   PUBMED   2289471
  REMARK    Erratum:[Epilepsy Res 1992 Mar;11(1):72]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY780023.1 and CT033776.8.
            
            On or before Mar 10, 2007 this sequence version replaced
            XM_148531.7, XM_001002402.1, XM_915403.2, XM_001001640.1,
            XM_001002270.1, XM_001002259.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M92418.1, BC138004.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               BY780023.1         1-293
            294-423             CT033776.8         183919-184048       c
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 25.52 cM"
     gene            1..423
                     /gene="Stfa2"
                     /gene_synonym="Stf2"
                     /note="stefin A2"
                     /db_xref="GeneID:20862"
                     /db_xref="MGI:MGI:106197"
     exon            1..114
                     /gene="Stfa2"
                     /gene_synonym="Stf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             31..342
                     /gene="Stfa2"
                     /gene_synonym="Stf2"
                     /codon_start=1
                     /product="stefin-2"
                     /protein_id="NP_001076014.1"
                     /db_xref="CCDS:CCDS37334.1"
                     /db_xref="GeneID:20862"
                     /db_xref="MGI:MGI:106197"
                     /translation="MTEYTIEIIGGLSEARPATSEIQEIADKVRPLLEEKTNEKYEKF
                     KAIEYKVQVVQGLNYFIKMNVGRGCYLHINVLSGISSENDLELTGYQTNKAKNDELTY
                     F"
     exon            115..216
                     /gene="Stfa2"
                     /gene_synonym="Stf2"
                     /inference="alignment:Splign:2.1.0"
     exon            217..423
                     /gene="Stfa2"
                     /gene_synonym="Stf2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      402..407
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stfa2"
                     /gene_synonym="Stf2"
                     /note="hexamer: AATAAA"
     polyA_site      418
                     /gene="Stfa2"
                     /gene_synonym="Stf2"
                     /note="major polyA site"
ORIGIN      
        1 gatcatttct tctcagcacc ctgcccagca atgactgaat acaccataga aataattgga
       61 ggtttgtcag aggccagacc tgccacatca gaaatccagg agattgctga caaggtcaga
      121 ccactgcttg aagagaaaac caatgagaaa tatgaaaaat tcaaagccat cgagtataaa
      181 gttcaagtcg tccaaggact aaattacttc attaagatga atgtaggacg tggttgctac
      241 ctccacataa acgtcttaag tggtatttcc agtgaaaacg atttggaact cactggttat
      301 cagactaaca aagcaaagaa tgatgagctg acctacttct aaacagcaga ttccaacttg
      361 acctgatccc ctaaccccca ttgtaaagag atgcggccat caataaagaa gcatttttga
      421 aat
//
