LOCUS       NM_001082543             418 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus stefin A1 (Stfa1), mRNA.
ACCESSION   NM_001082543
VERSION     NM_001082543.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 418)
  AUTHORS   Mezzapesa,A., Bastelica,D., Crescence,L., Poggi,M., Grino,M.,
            Peiretti,F., Panicot-Dubois,L., Dupont,A., Valero,R.,
            Maraninchi,M., Bordet,J.C., Alessi,M.C., Dubois,C. and Canault,M.
  TITLE     Increased levels of the megakaryocyte and platelet expressed
            cysteine proteases stefin A and cystatin A prevent thrombosis
  JOURNAL   Sci Rep 9 (1), 9631 (2019)
   PUBMED   31270351
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 418)
  AUTHORS   Liu,X., Jiao,Y., Cao,Y., Deng,N., Ma,Y., Hasty,K.A., Kang,A.,
            Chen,H., Stuart,J.M. and Gu,W.
  TITLE     Decreased expression levels of Ifi genes is associated to the
            increased resistance to spontaneous arthritis disease in mice
            deficiency of IL-1RA
  JOURNAL   BMC Immunol 17 (1), 25 (2016)
   PUBMED   27480124
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 418)
  AUTHORS   Lazic,D., Alborzi,F., Marcuzzi,G.P., Angel,P., Hess,J., Pfister,H.
            and Akgul,B.
  TITLE     Enhanced StefinA and Sprr2 expression during papilloma formation in
            HPV8 transgenic mice
  JOURNAL   J Dermatol Sci 62 (2), 84-90 (2011)
   PUBMED   21458245
  REMARK    GeneRIF: In non-lesional HPV8-CER transgenic skin StefinA and Sprr2
            are indirect/direct transcriptional targets of HPV8
REFERENCE   4  (bases 1 to 418)
  AUTHORS   Mihelic,M., Teuscher,C., Turk,V. and Turk,D.
  TITLE     Mouse stefins A1 and A2 (Stfa1 and Stfa2) differentiate between
            papain-like endo- and exopeptidases
  JOURNAL   FEBS Lett 580 (17), 4195-4199 (2006)
   PUBMED   16831429
REFERENCE   5  (bases 1 to 418)
  AUTHORS   Roper,R.J., McAllister,R.D., Biggins,J.E., Michael,S.D., Min,S.H.,
            Tung,K.S., Call,S.B., Gao,J. and Teuscher,C.
  TITLE     Aod1 controlling day 3 thymectomy-induced autoimmune ovarian
            dysgenesis in mice encompasses two linked quantitative trait loci
            with opposing allelic effects on disease susceptibility
  JOURNAL   J Immunol 170 (12), 5886-5891 (2003)
   PUBMED   12794114
REFERENCE   6  (bases 1 to 418)
  AUTHORS   Liao,X., Gilbert,D.J., Dent,A., Staudt,L.M., Jenkins,N.A. and
            Copeland,N.G.
  TITLE     Mapping of the mouse Bcl6 gene to chromosome 16
  JOURNAL   Mamm Genome 7 (8), 621-622 (1996)
   PUBMED   8678989
REFERENCE   7  (bases 1 to 418)
  AUTHORS   Sharma,S., Leonard,J., Lee,S., Chapman,H.D., Leiter,E.H. and
            Montminy,M.R.
  TITLE     Pancreatic islet expression of the homeobox factor STF-1 relies on
            an E-box motif that binds USF
  JOURNAL   J Biol Chem 271 (4), 2294-2299 (1996)
   PUBMED   8567692
REFERENCE   8  (bases 1 to 418)
  AUTHORS   Mlinaric-Rascan,I., Asa,S.L. and Siminovitch,K.A.
  TITLE     Increased expression of the stefin A cysteine proteinase inhibitor
            occurs in the myelomonocytic cell-infiltrated tissues of autoimmune
            motheaten mice
  JOURNAL   Am J Pathol 145 (4), 902-912 (1994)
   PUBMED   7943179
REFERENCE   9  (bases 1 to 418)
  AUTHORS   Rutherford,M.S., Rock,C.O., Jenkins,N.A., Gilbert,D.J.,
            Tessner,T.G., Copeland,N.G. and Jackowski,S.
  TITLE     The gene for murine CTP:phosphocholine cytidylyltransferase (Ctpct)
            is located on mouse chromosome 16
  JOURNAL   Genomics 18 (3), 698-701 (1993)
   PUBMED   8307580
REFERENCE   10 (bases 1 to 418)
  AUTHORS   Tsui,F.W., Tsui,H.W., Mok,S., Mlinaric,I., Copeland,N.G.,
            Gilbert,D.J., Jenkins,N.A. and Siminovitch,K.A.
  TITLE     Molecular characterization and mapping of murine genes encoding
            three members of the stefin family of cysteine proteinase
            inhibitors
  JOURNAL   Genomics 15 (3), 507-514 (1993)
   PUBMED   8468045
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY113926.1 and BG074171.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CJ237916.1, CJ238997.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-328               BY113926.1         1-328
            329-418             BG074171.2         1-90                c
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 25.45 cM"
     gene            1..418
                     /gene="Stfa1"
                     /gene_synonym="Stefin-3; Stf-3; Stf1; Stf3; Stfa3"
                     /note="stefin A1"
                     /db_xref="GeneID:20861"
                     /db_xref="MGI:MGI:106198"
     exon            1..114
                     /gene="Stfa1"
                     /gene_synonym="Stefin-3; Stf-3; Stf1; Stf3; Stfa3"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..342
                     /gene="Stfa1"
                     /gene_synonym="Stefin-3; Stf-3; Stf1; Stf3; Stfa3"
                     /codon_start=1
                     /product="stefin-1"
                     /protein_id="NP_001076012.1"
                     /db_xref="CCDS:CCDS37331.1"
                     /db_xref="GeneID:20861"
                     /db_xref="MGI:MGI:106198"
                     /translation="MSLGGVSEASRATPEIQMIANKVRPQLEAKTNKKYEKFEAVEYK
                     TQVVAGENIFIKMDVGHGCFIHIKVFNGPTGKDNYELHGYQTDKTMDEELTYF"
     exon            115..216
                     /gene="Stfa1"
                     /gene_synonym="Stefin-3; Stf-3; Stf1; Stf3; Stfa3"
                     /inference="alignment:Splign:2.1.0"
     exon            217..418
                     /gene="Stfa1"
                     /gene_synonym="Stefin-3; Stf-3; Stf1; Stf3; Stfa3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatcatttct tctcagtgtc caagccagca aagaagcaac gcatcaagat gagtcttgga
       61 ggtgtttcag aggcaagccg tgccacacca gaaatccaga tgattgctaa caaggtcaga
      121 cctcagcttg aagcaaaaac caataagaaa tatgaaaaat tcgaagccgt tgagtataaa
      181 actcaagtcg tcgctggaga aaatatcttc attaagatgg atgtaggtca tggttgtttc
      241 attcacataa aagtcttcaa tggacctact ggaaaagata attatgaact tcatggttac
      301 cagactgaca aaaccatgga tgaagagctg acctacttct aagcagcaaa ttctaaagtg
      361 atctgattcc tctcagtgga aagagattca gccatgaata aagaaatatt cctcaact
//
