LOCUS       NM_054098               3140 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Mus musculus STEAP family member 4 (Steap4), mRNA.
ACCESSION   NM_054098
VERSION     NM_054098.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3140)
  AUTHORS   Zhu,L., Li,B., Chen,D., Chen,N., Xu,L., Li,Q. and Chen,X.
  TITLE     sSTEAP4 regulates cellular homeostasis and improves
            high-fat-diet-caused oxidative stress in hepatocytes
  JOURNAL   Life Sci 296, 120438 (2022)
   PUBMED   35227772
  REMARK    GeneRIF: sSTEAP4 regulates cellular homeostasis and improves
            high-fat-diet-caused oxidative stress in hepatocytes.
REFERENCE   2  (bases 1 to 3140)
  AUTHORS   Mollenhauer,M., Bokredenghel,S., Geissen,S., Klinke,A.,
            Morstadt,T., Torun,M., Strauch,S., Schumacher,W., Maass,M.,
            Konradi,J., Peters,V.B.M., Berghausen,E., Vantler,M.,
            Rosenkranz,S., Mehrkens,D., Braumann,S., Nettersheim,F., Hof,A.,
            Simsekyilmaz,S., Winkels,H., Rudolph,V., Baldus,S., Adam,M. and
            Freyhaus,H.T.
  TITLE     Stamp2 Protects From Maladaptive Structural Remodeling and Systolic
            Dysfunction in Post-Ischemic Hearts by Attenuating Neutrophil
            Activation
  JOURNAL   Front Immunol 12, 701721 (2021)
   PUBMED   34691017
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3140)
  AUTHORS   Zhao,J., Liao,Y., Miller-Little,W., Xiao,J., Liu,C., Li,X., Li,X.
            and Kang,Z.
  TITLE     STEAP4 expression in CNS resident cells promotes Th17 cell-induced
            autoimmune encephalomyelitis
  JOURNAL   J Neuroinflammation 18 (1), 98 (2021)
   PUBMED   33879167
  REMARK    GeneRIF: STEAP4 expression in CNS resident cells promotes Th17
            cell-induced autoimmune encephalomyelitis.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3140)
  AUTHORS   Batool,M., Berghausen,E.M., Zierden,M., Vantler,M., Schermuly,R.T.,
            Baldus,S., Rosenkranz,S. and Ten Freyhaus,H.
  TITLE     The six-transmembrane protein Stamp2 ameliorates pulmonary vascular
            remodeling and pulmonary hypertension in mice
  JOURNAL   Basic Res Cardiol 115 (6), 68 (2020)
   PUBMED   33188479
  REMARK    GeneRIF: The six-transmembrane protein Stamp2 ameliorates pulmonary
            vascular remodeling and pulmonary hypertension in mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3140)
  AUTHORS   Kim,H.Y., Kwon,W.Y., Park,J.B., Lee,M.H., Oh,Y.J., Suh,S.,
            Baek,Y.H., Jeong,J.S. and Yoo,Y.H.
  TITLE     Hepatic STAMP2 mediates recombinant FGF21-induced improvement of
            hepatic iron overload in nonalcoholic fatty liver disease
  JOURNAL   FASEB J 34 (9), 12354-12366 (2020)
   PUBMED   32721044
  REMARK    GeneRIF: Hepatic STAMP2 mediates recombinant FGF21-induced
            improvement of hepatic iron overload in nonalcoholic fatty liver
            disease.
REFERENCE   6  (bases 1 to 3140)
  AUTHORS   Yu,X., Bauer,K., Koczan,D., Thiesen,H.J. and Ibrahim,S.M.
  TITLE     Combining global genome and transcriptome approaches to identify
            the candidate genes of small-effect quantitative trait loci in
            collagen-induced arthritis
  JOURNAL   Arthritis Res Ther 9 (1), R3 (2007)
   PUBMED   17244351
REFERENCE   7  (bases 1 to 3140)
  AUTHORS   Ohgami,R.S., Campagna,D.R., McDonald,A. and Fleming,M.D.
  TITLE     The Steap proteins are metalloreductases
  JOURNAL   Blood 108 (4), 1388-1394 (2006)
   PUBMED   16609065
REFERENCE   8  (bases 1 to 3140)
  AUTHORS   Fasshauer,M., Kralisch,S., Klier,M., Lossner,U., Bluher,M.,
            Chambaut-Guerin,A.M., Klein,J. and Paschke,R.
  TITLE     Interleukin-6 is a positive regulator of tumor necrosis factor
            alpha-induced adipose-related protein in 3T3-L1 adipocytes
  JOURNAL   FEBS Lett 560 (1-3), 153-157 (2004)
   PUBMED   14988015
  REMARK    GeneRIF: Tiarp is stimulated by tumor necrosis factor-alpha in
            adipocytes.
REFERENCE   9  (bases 1 to 3140)
  AUTHORS   Porkka,K.P., Helenius,M.A. and Visakorpi,T.
  TITLE     Cloning and characterization of a novel six-transmembrane protein
            STEAP2, expressed in normal and malignant prostate
  JOURNAL   Lab Invest 82 (11), 1573-1582 (2002)
   PUBMED   12429817
REFERENCE   10 (bases 1 to 3140)
  AUTHORS   Moldes,M., Lasnier,F., Gauthereau,X., Klein,C., Pairault,J.,
            Feve,B. and Chambaut-Guerin,A.M.
  TITLE     Tumor necrosis factor-alpha-induced adipose-related protein
            (TIARP), a cell-surface protein that is highly induced by tumor
            necrosis factor-alpha and adipose conversion
  JOURNAL   J Biol Chem 276 (36), 33938-33946 (2001)
   PUBMED   11443137
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC133514.4.
            
            [WARNING] On Mar 5, 2024 this sequence was replaced by NM_054098.4.
            
            On Nov 17, 2006 this sequence version replaced NM_054098.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC006651.1, AK040760.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                AC133514.4         40467-40536         c
            71-528              AC133514.4         25112-25569         c
            529-1056            AC133514.4         23986-24513         c
            1057-1221           AC133514.4         22436-22600         c
            1222-3140           AC133514.4         18795-20713         c
FEATURES             Location/Qualifiers
     source          1..3140
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 3.37 cM"
     gene            1..3140
                     /gene="Steap4"
                     /gene_synonym="1110021O17Rik; Tiarp; Tnfaip9"
                     /note="STEAP family member 4"
                     /db_xref="GeneID:117167"
                     /db_xref="MGI:MGI:1923560"
     exon            1..70
                     /gene="Steap4"
                     /gene_synonym="1110021O17Rik; Tiarp; Tnfaip9"
                     /inference="alignment:Splign:2.1.0"
     exon            71..528
                     /gene="Steap4"
                     /gene_synonym="1110021O17Rik; Tiarp; Tnfaip9"
                     /inference="alignment:Splign:2.1.0"
     exon            529..1056
                     /gene="Steap4"
                     /gene_synonym="1110021O17Rik; Tiarp; Tnfaip9"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1221
                     /gene="Steap4"
                     /gene_synonym="1110021O17Rik; Tiarp; Tnfaip9"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..3140
                     /gene="Steap4"
                     /gene_synonym="1110021O17Rik; Tiarp; Tnfaip9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcaagcct agaaggcaga gcccaccgca gccgcgccag accaacgccc ctccgggcgc
       61 ctcgccgcag taatggagaa agcacatgca gatgagtttc ctctgactac tgattcctca
      121 gaaaagcaag gggttgtctg cattttcgga acaggagatt tcgggaagtc actgggattg
      181 aaaatgcttc agtgtggcta ttctatcgtt tttgggagtc gaaaccccca ggtgtccagc
      241 cttctgccca ggggggcaga ggtcctgagc tattcggaag cagcatccaa gtctgacatc
      301 ataatcctag ccatgcacag agagcactat gattccctca cggaactagt tgattatctc
      361 aaaggaaaag tattggtaga cgtcagtaac aaccgcaaaa tcaatcagta tccagagtca
      421 aatgcggaat accttgctca gctggagcca ggagcccacg tggtcaaagc atttaacacc
      481 atctcagcct gggctctcca gtcaggaaca ctagatgcaa gccggcaggt gtttgtctgt
      541 ggaaatgaca gcaaggccaa acaaagagta atggacattg ctcgtactct tgggctcacc
      601 ccactggacc aaggatctct catggcagcc agtgaaattg aaaactaccc tctgcaacta
      661 tttccaatgt ggaggtttcc tttctatttg tcctctgtgc tgtgcgtctt cttctttgtg
      721 tactgtgcaa tacgagaggt gatatacccc tacgtgaatg ggaaaacaga tgctacgtac
      781 cgcctggcca tttccatccc gaatcgtgtc tttcctataa cagcactgat cctgcttgcc
      841 ttggtgtacc tccctggtat tctcgctgcc attctgcagc tctatcgagg cacaaagtac
      901 cgccgattcc caaactggct tgaccattgg atgctttgca gaaagcaact gggcttggta
      961 gctctgggat ttgccttcct tcatgtcatc tacacacttg tgattcctat ccgttactat
     1021 gttcgatgga ggctgagaaa tgcaaccatt actcaggccc taactaataa agacagccca
     1081 tttattacct cttatgcctg gattaatgat tcctacttgg cgctgggaat cctgggattt
     1141 tttctgttcc ttctgttggg aatcacttcc ttgccatcag taagcaacat ggtcaactgg
     1201 agagagttcc ggtttgttca gtccaaactg ggttatctga ccctggtctt gtgcacagcc
     1261 cacactttgg tgtatggcgg aaagagattc ctcagccctt cgattctaag gtggagcctc
     1321 ccttcggctt atattttggc actcgtcatc ccctgcgcag tgctggtgct gaagtgcatc
     1381 ctcatcatgc catgcataga caagaccctc actcgcatcc gccagggctg ggaaagaaac
     1441 tcaaagtaca cacaatcagc actgaacgga aaatcggata tttaagctac agttgaattt
     1501 gccaggattt gtgtactatt gcagtaaatg tttagagcat aatgtgtcca gttataagaa
     1561 agcattttct cttgtcatgg ccctaacttt atcatcacag taggaagtgt tgcctcactt
     1621 tgaaagacca gaatagcaag ggaaccctcg ctgcctcagt cacgtgatga ctcattgtgg
     1681 gcctccctca cttcctttcc cagaaacccc agggatgcca ctgtgattag atttacagtt
     1741 ccacacagcg aagcttcttg attatgggca agttgaatga cgcaatgttt tgtagagttc
     1801 tggaagagtg tgtgcaactt ccttccctaa ttcaagggct gatgtaagtg aaaaagcagc
     1861 actcggcata ctacaggttt tgcttggcat gcctggagaa aagccccaaa tgaaatagac
     1921 agaaagaggg ttagtttgtt tcctggaaga agtggtgatc ataactattg tcatactgat
     1981 ctgggggtat ttggggttta gctgtagtgc tgagctcaaa cctaaggcct tatgcatgtt
     2041 aggtaaatga tatgttactg agccacacac acgccagccg tgccatagtg agtatgtagt
     2101 catatgtacc cccttgattt cttgctttta ccaatatgga ttcttactat ggggaaatat
     2161 tttatactgc aacaaaattg gtttgaagta gctgttcctt ggatatatgg aaagctatgt
     2221 aattgtccca agattcttcc tccacaaagg acggcttgag gggagatggg gtaagagttg
     2281 agcagcgatc ctaagttgag ggaagatggg gaaagagtgg aagatccatt gggtttttca
     2341 agtgccgcag gcagacacag gctgataata gccttgtaca aaaatgtcag ataagccaga
     2401 attttagcta gtaagctacg caaatactaa tacagtttca ctatgctgtt tgggatcatt
     2461 taggagtggt ggtgtgcttt cttcattata catttcaaat actgttcagt attaagcatc
     2521 tgtgaaatta acttctagta caaacatgta gcttccataa tctgtctttg ttatcaatgt
     2581 aagtggtgca gttagaagga atcatctgaa ctcgtcggag cgaggaaagg atagctgaga
     2641 gaactgtgga gtgctagggt gtaggcgagc agcagtggac catgggtcgg atgcagccag
     2701 ctctggcttc ctgtgtggac agtgcctttc ccaaggtgac cttcagcagg ctgagaatcc
     2761 ttagctctag cctggagcta aaaggagatc tttgcacaat cttcccgcgt gtcactgaaa
     2821 taaagaaaag gcattgagtt tgacattttt ctgattaatc tacaaagact gtttattttt
     2881 catttttcta gcttttatat cgtatattgt acatgatatc atacattgct cacaatccag
     2941 ggttttttat ataaagctct tatataacac agacatttct tttactattg ccctaataaa
     3001 acatatagag tatattcagt ttttactaag aggacaattg aggtaatgtc tttgtactaa
     3061 caaaatattt ctgtattttc aattatttcc ttggaatatt ttccaagagt tagtataaaa
     3121 ttaaagaata tttgataaca
//
