LOCUS       NM_199018               4983 bp    mRNA    linear   ROD 19-NOV-2024
DEFINITION  Mus musculus StAR related lipid transfer domain containing 8
            (Stard8), mRNA.
ACCESSION   NM_199018 XM_135985
VERSION     NM_199018.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4983)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4983)
  AUTHORS   Nahaboo,W., Eski,S.E., Despin-Guitard,E., Vermeersch,M.,
            Versaevel,M., Saykali,B., Monteyne,D., Gabriele,S., Magin,T.M.,
            Schwarz,N., Leube,R.E., Zwijsen,A., Perez-Morga,D., Singh,S.P. and
            Migeotte,I.
  TITLE     Keratin filaments mediate the expansion of extra-embryonic
            membranes in the post-gastrulation mouse embryo
  JOURNAL   EMBO J 41 (7), e108747 (2022)
   PUBMED   35266581
REFERENCE   3  (bases 1 to 4983)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4983)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   5  (bases 1 to 4983)
  AUTHORS   Tuck,E., Estabel,J., Oellrich,A., Maguire,A.K., Adissu,H.A.,
            Souter,L., Siragher,E., Lillistone,C., Green,A.L., Wardle-Jones,H.,
            Carragher,D.M., Karp,N.A., Smedley,D., Adams,N.C., Bussell,J.N.,
            Adams,D.J., Ramirez-Solis,R., Steel,K.P., Galli,A. and White,J.K.
  CONSRTM   Sanger Institute Mouse Genetics Project
  TITLE     A gene expression resource generated by genome-wide lacZ profiling
            in the mouse
  JOURNAL   Dis Model Mech 8 (11), 1467-1478 (2015)
   PUBMED   26398943
REFERENCE   6  (bases 1 to 4983)
  AUTHORS   Boyle,M.P., Bernard,A., Thompson,C.L., Ng,L., Boe,A., Mortrud,M.,
            Hawrylycz,M.J., Jones,A.R., Hevner,R.F. and Lein,E.S.
  TITLE     Cell-type-specific consequences of Reelin deficiency in the mouse
            neocortex, hippocampus, and amygdala
  JOURNAL   J Comp Neurol 519 (11), 2061-2089 (2011)
   PUBMED   21491433
REFERENCE   7  (bases 1 to 4983)
  AUTHORS   Durkin,M.E., Ullmannova,V., Guan,M. and Popescu,N.C.
  TITLE     Deleted in liver cancer 3 (DLC-3), a novel Rho GTPase-activating
            protein, is downregulated in cancer and inhibits tumor cell growth
  JOURNAL   Oncogene 26 (31), 4580-4589 (2007)
   PUBMED   17297465
REFERENCE   8  (bases 1 to 4983)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   9  (bases 1 to 4983)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY251063.1, AK149830.1 and BC062944.1.
            
            On Oct 31, 2009 this sequence version replaced NM_199018.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062944.1, AK133927.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                BY251063.1         2-71
            71-3730             AK149830.1         2-3661
            3731-4983           BC062944.1         3646-4898
FEATURES             Location/Qualifiers
     source          1..4983
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 43.19 cM"
     gene            1..4983
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /note="StAR related lipid transfer domain containing 8"
                     /db_xref="GeneID:236920"
                     /db_xref="MGI:MGI:2448556"
     exon            1..214
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            215..286
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            287..368
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            369..432
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            433..1838
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..2012
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            2013..2172
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2371
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            2372..2582
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            2583..2697
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            2698..2922
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            2923..3140
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            3141..3317
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     exon            3318..4963
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4941..4946
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /note="hexamer: AATAAA"
     polyA_site      4963
                     /gene="Stard8"
                     /gene_synonym="Dlc3; mKIAA0189"
                     /note="major polyA site"
ORIGIN      
        1 gtaggtgggc ggagcaccac tacggcttac tcgcgaatgc tccctctctc cgaacctgcg
       61 cggcgagcat agtctagttg acaacggcta agcagctact atagctgcaa ttctggctcg
      121 cacctttacc cctggctcca cgcgtgtctt cttcgagcag ccctgcccgc gcttgcctcc
      181 tatccctttg ccgctgtgtg gacgcggctg ccaaaagcgg aggccaaaaa agcatgtgaa
      241 tggctccggg ccacaggatt ctctcagtat gctcagcttt ttgaagaagg tgtattcccc
      301 ctggatattg gctctgtgaa gaaggactac agttttctgg accaggactc tctgggggcc
      361 ctgtgcagga ggctgatgac cctgaacaat tgtgcttcga tgaagcttga ggttcatttt
      421 caatgcaagc aggatgacga ctcagaagag gaggagcaat gcaccattag cagccactgg
      481 gcctttgagc aggaaagcaa gtgtgggtct ctcatgggct cttctgccct gctggcccca
      541 ccaagcccta gcctcctggg gacctcaagc tgcgaaagcg tcctcactga gcttagcgct
      601 gcctccctgc cagccatctc cgcgagcctt tcaccagagt cagcagacca gcccttgtta
      661 ggtcttgtcc ccagcccaag taaccaaccc ttccttagtc ccccccaagg ccaggagggt
      721 tcccaagaca aagtaaagaa gcattattct cgaagcttcc tcaagcacct tgaatctctg
      781 aggaggaaag aaaagggtga cagccggcag acagaacccg agcaatgcct tgccacctcg
      841 gaaaaggcca ccaaagcttc atctttccgc acttgccgtg gcttcctctc agctggattt
      901 cacagggcca agaacagggt caccacttca gccagggtca gagatggtga gactcagaaa
      961 gcctgggagg cttggcctgt agccacattc cggcatcctc agcctatacg caggcgtgac
     1021 tatctggtgc atgtgcctgg ggaccataag ccaggcacgt tccctcgttc tctgtccatt
     1081 gagagccttt gtccagatga aggtcgtcac ctggcagatt ggcagtcaag taggtgctgg
     1141 ggctatgaag ggcgccgggg ctcctgtggt tccacaggca gccatgccag cacttacgac
     1201 aacttgcctg agctgtaccc agctgagcct atacaggctg aagctgaggc tgaagctgag
     1261 gagggtgaag gcagctatgc ccatctagat gacatcctgg agcatgtgtg ggggctacag
     1321 caacgggtag agctgtggtc tcagaccatg tacccagacc tgaggcctgg agataaggag
     1381 gaagaggagg aggaggagga ggaagaggag gaagctactt catcagtgga agtagccaca
     1441 gtggaggtgg aaggccagga tgaagatcta gctcaggcag agtctcaagc ccacagaggg
     1501 ttcccaaccc aagtcaagga ggaagtccca ctgattgttc tggatcaggc cccaaatgtg
     1561 gtcgaaccat tggtacaggc tgaggctgag gctccagctc aggcccagga tcttgagcaa
     1621 gaagctaact cgactgcaga gccaatttct gcctccagcc tgtctgtgga ggaagggcat
     1681 tccatttctg acacagcggt ttcctccagt gagcttgaca gtagtggcaa ctccatgaat
     1741 gaggctgatg ctgcagacgc ccctgcagga ctgcaagcat cagtaccccg tgaacgtcgt
     1801 gactcaggtg tcggggcctc gcttaccaga ccatgcagga aacttcgttg gcacagcttc
     1861 cagaattccc accgacctag cctcaactca gagtcactgg agatcaacag gcagtttgca
     1921 ggccagatca acttgcttca caagggctca ctgctgcggc tcactggctt catggagaag
     1981 tacactgtac cccacaaaca ggcctgggta tggtcaatgc ccaagtttat gaaaagaaac
     2041 aagaccccag actaccgggg acaccatgta tttggggtgc cacccctcat tcatgtgcag
     2101 cgcacaggcc agcctctgcc tcagagcatc cagcaagcta tgcgatacct acgaagccag
     2161 tgcctagacc aggtgggcat ctttcgcaag tctggggtca agtccaggat tcagagccta
     2221 cgccaaatga atgagaactc ccctgacaat gtctgctatg agggccagtc ggcctatgat
     2281 gtggctgatt tactgaagca gtatttcaga gacctgcctg agcccatttt taccagcaag
     2341 ctcaccacta ctttcctaca aatctatcag ctcctcccca aagaacagtg gctggcagcg
     2401 gcgcaagctg ccaccttgct gctccctgat gagaaccgag aagtgctgca gaccctgctc
     2461 tacttcctaa gtgacatcgc ctctgccgag gaaaaccaga tgacagctgg caacctggcg
     2521 gtgtgcctgg caccttccat cttccacctc aatgtctcca agaaggacag ctcctcaccc
     2581 aggatcaaga gcaaacgcag cctggttggc cggccaggcc ccagggacct gagtgagaac
     2641 atggctgcca cccaaggcct atcacacatg atcagtgact gcaagaaact tttccaggtg
     2701 ccccaggaca tggtggtgca gctatgtggt tcatacagcg cagctgagct cagccctcct
     2761 ggcccagccc tggctgagct gaggcaggcc caggcggctg gggtgagtct aagcctttac
     2821 atggaggaga gtgtgcagga gctgcttcgg gatgctgcag aacgcttcaa gggctggacc
     2881 aatgtgccgg ggccccagca cacagagctg gcttgtagga aggcaccaga tgggcacccg
     2941 cttcgaatgt ggaaggcatc cacagaagtg gctgcccctc cagccgtggt gctgcatcgt
     3001 gtccttcggg agcgggcctt gtgggatgag gacctcctgc gggcccaggt gctggaagcc
     3061 ctgatgccag gtgtggagct gtaccactat gtcactgaca gcatggcacc tcatccttgc
     3121 cgtgattttg tggtgctcag gatgtggcgc tcggacctgc ctcgtggtgg gtgcctcctt
     3181 gtctctcagt ccctggatcc tgagcaaccc gtgccagagt ctggagtacg cgccctcatg
     3241 ctcacttccc agtacctcat ggaaccctgt ggcctgggcc gctctcgcct cactcatatt
     3301 tgccgcgctg acctcagggg ccgttctcct gactggtaca acaaagtctt tgggcacttg
     3361 tgtgccatgg aagtggcaaa gatccgagac tctttcccaa cccttcaggc agctggcccg
     3421 gaaacaaagc tctgagtctt aggctgacat tgccaggtgt ctgccaccaa agaaatgagt
     3481 gggaatatga actgagaagc ctttagagac acagccaggc ctcggtggcc cagctaccta
     3541 tcctcttgta tcctaatgct actctgcaca cacacaagag aagagggcgt aggtatccta
     3601 cctccaccca ccttcatccc cgatactgca ttctgatctc acaagcgaag agaatcttgt
     3661 tagtggcaag aagatcattg ctgtccatct gaccaagaag acgctgctgt atctggaggc
     3721 ccagcagggg aagaaggtgg agagccttgg acagcctggg ctctctgcca taccaagtag
     3781 gcaggccatc ttatttggtg ctagggttct tttgagtttg aatatgaggt ctgatcctgc
     3841 ctttggggcc aacattgatc ctgaatacag gtctggaaca ccagatcggg taagcacggg
     3901 ggacacaatg accaccacaa tccattttat atgtgaacat gatgctgaac tttctgaaga
     3961 ttgacagtgg ccctatgggc ccttagtagg taacatgaca aactgggata acttgggatc
     4021 tgaggttaga ggacctttct tcctcaagcc caagaaacca atgaaccatc ctcccctact
     4081 ttgacccaca ctttatccat tactctctag agttgtgggc agcctttggc cactcatggc
     4141 catagataca agtgaaatag ctcattccca tgacacaggc caggccaaag ctgacagtgg
     4201 cagcaagaaa tacaaatgta tcctcatgcc ttttgcctac agtggtggtc tataagaaca
     4261 gtccttttgg ctggagaggt ggcatagtgg ttaagagcag tggctgctct tccagaggac
     4321 ctaaaagttc aattcccagc aatcgcaggg tggttcacaa ccatctgtaa tgagatctga
     4381 tgccctcttc tgtagtgttt gaagacagct acagtgtact gatatacata ataaataaat
     4441 agataaataa atcttttata aaaagcaaaa ccaagtgtcc ttaaaaagaa aaagaaaagt
     4501 ccattcctag agtagacacc ctagaaaaac acaaagaagg gcgtacctta gccatcctgg
     4561 ctgataccag cctgatctat cccatctagt ggttatgttt gttcagatag aaaccgagca
     4621 gccattcaga ggccaagtgg tgctttcttt gtctttggct gagtaaactg gattgtggtg
     4681 gtttgtagcc atcgttgtga tgttaatcct gttttgtctg tgcctataaa tactgtacag
     4741 ccataatata tatgtgtatg tgtatatata tacatatgta tatacctata catatacaca
     4801 catatttgca tgcacacaca gctactccct cttgagtgcg ttataatctc tggatgggag
     4861 cagggtctgg actaacacac ttctgttcta acgagagagg agaggtgaag ggcaggccgc
     4921 agcagttccc tctgcagaat aataaagcag gactggagat gcaaaaaaaa aaaaaaaaaa
     4981 aaa
//
