LOCUS       NM_024270               1362 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus STARD3 N-terminal like (Stard3nl), transcript variant
            1, mRNA.
ACCESSION   NM_024270
VERSION     NM_024270.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Xu,Y., Bao,X., Chen,X., Wu,P., Chen,S., Zhang,B., Ma,J., Xu,G. and
            Ma,D.
  TITLE     STARD3NL inhibits the osteogenic differentiation by inactivating
            the Wnt/beta-catenin pathway via binding to Annexin A2 in
            osteoporosis
  JOURNAL   J Cell Mol Med 26 (5), 1643-1655 (2022)
   PUBMED   35098646
  REMARK    GeneRIF: STARD3NL inhibits the osteogenic differentiation by
            inactivating the Wnt/beta-catenin pathway via binding to Annexin A2
            in osteoporosis.
REFERENCE   2  (bases 1 to 1362)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   3  (bases 1 to 1362)
  AUTHORS   Alpy,F., Wendling,C., Rio,M.C. and Tomasetto,C.
  TITLE     MENTHO, a MLN64 homologue devoid of the START domain
  JOURNAL   J Biol Chem 277 (52), 50780-50787 (2002)
   PUBMED   12393907
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV648392.1, BG084215.2, CO039188.1 and BP772163.1.
            
            On Apr 15, 2015 this sequence version replaced NM_024270.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript but encodes the shorter isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003334.1, AK152116.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                DV648392.1         1-17
            18-61               DV648392.1         19-62
            62-784              BG084215.2         1-723
            785-1342            CO039188.1         15-572              c
            1343-1362           BP772163.1         28-47               c
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 6.89 cM"
     gene            1..1362
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /note="STARD3 N-terminal like"
                     /db_xref="GeneID:76205"
                     /db_xref="MGI:MGI:1923455"
     exon            1..110
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     exon            111..393
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     CDS             169..876
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /note="isoform a is encoded by transcript variant 1; MLN64
                     N-terminal domain homolog; STARD3 N-terminal-like protein"
                     /codon_start=1
                     /product="STARD3 N-terminal-like protein isoform a"
                     /protein_id="NP_077232.2"
                     /db_xref="CCDS:CCDS26259.1"
                     /db_xref="GeneID:76205"
                     /db_xref="MGI:MGI:1923455"
                     /translation="MNHLPEHMENTLTGSQSSHASLRDIHSINPAQLMARIESYEGRE
                     KKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLKKEVIHYDYYSSYFDIFL
                     LAVFRFKVLILGYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIIS
                     FILAWIETWFLDFKVLPQEAEEENRLLLVQDASERAALIPAGLSDGQFYSPPESEAGS
                     EEEAEEKQESEKPLLEL"
     exon            394..471
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     exon            472..549
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     exon            550..603
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     exon            604..721
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     exon            722..817
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     exon            818..891
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1345
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1322..1327
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /note="hexamer: AATAAA"
     polyA_site      1345
                     /gene="Stard3nl"
                     /gene_synonym="0610035N01Rik; 6530409L22Rik; MENTHO"
                     /note="major polyA site"
ORIGIN      
        1 cgcgttgacg tcacggacag ggtcccgccc tgcagccccg ccccagcccc gccggcgggg
       61 accgcggagc cgtgtctgca ggccggcggg cggctcgcgc cgcggaggag gttgcttctc
      121 actagggatg gtggagttgg atggagactc cttcagtcct cctccaggat gaaccatctt
      181 ccagaacaca tggagaacac tctgacgggg agccagagct cacacgcttc tctgcgagac
      241 atccattcca tcaaccctgc gcagctcatg gccaggattg agtcctatga aggaagggaa
      301 aagaaaggca tttctgatgt caggaggact ttttgtctct ttgtcacctt tgacctctta
      361 tttgtaacgt tactgtggat aatagagtta aatgtgaacg gaggcatcga gaacaccctg
      421 aagaaggaag tgattcacta tgactactac tcctcttact ttgatatatt tcttttggca
      481 gtttttcgat tcaaagtgct gatacttggg tatgctgtat gcagattgcg ccattggtgg
      541 gcaatagcgt taacaacagc agtgaccagt gcctttctat tagcaaaagt gatcctctca
      601 aagcttttct ctcaaggggc atttggctat gtattgccca tcatttcatt catccttgcc
      661 tggattgaga cgtggttcct ggatttcaaa gtgttacctc aagaggcaga agaagaaaac
      721 agactcctgc tcgttcagga tgcgtccgag agggcggctc tcatccctgc agggctctct
      781 gatggtcagt tttactcccc tcctgagtct gaagcaggat ctgaagaaga agctgaggaa
      841 aaacaggaga gtgagaaacc gcttttggaa ctatgagttc tgctctgtga atgtgaagaa
      901 cctcactgcg agtcatccaa ggaagacagc tgaagtggtg gctctgcttg ctgctggatg
      961 ctgaggagct agtgagttta tttatggtga tacctcatgg acatcgctcc acctccactc
     1021 aaaccatccc tgcctgcggc cactgggtca tgctgtgctc cttcctctag tctgtgagtt
     1081 tcggtctgac ctgataatga ataactcggt cttgtgctgc atctgaatca aaagactgct
     1141 taatatattg aaataacaat tttgtagtaa gtgagagata cctttttgtt tcaattctca
     1201 gaatgtattt tttttttttg gtttcatgtc tcagatttct tttgtatttc ttttttaact
     1261 ccttacattt cacttgtgtt tttaaactca tgcacatgtg ctctttatac agttttaaaa
     1321 taataaatcc aacgtatcaa aatgaaaaaa aaaaaaaaaa aa
//
