LOCUS       NM_021547               2100 bp    mRNA    linear   ROD 15-SEP-2023
DEFINITION  Mus musculus StAR related lipid transfer domain containing 3
            (Stard3), mRNA.
ACCESSION   NM_021547
VERSION     NM_021547.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  AUTHORS   Almarhoun M, Biswas L, Alhasani RH, Wong A, Tchivelekete GM, Zhou
            X, Patterson S, Bartholomew C and Shu X.
  TITLE     Overexpression of STARD3 attenuates oxidized LDL-induced oxidative
            stress and inflammation in retinal pigment epithelial cells
  JOURNAL   Biochim Biophys Acta Mol Cell Biol Lipids 1866 (7), 158927 (2021)
   PUBMED   33771709
  REMARK    GeneRIF: Overexpression of STARD3 attenuates oxidized LDL-induced
            oxidative stress and inflammation in retinal pigment epithelial
            cells.
REFERENCE   3  (bases 1 to 2100)
  AUTHORS   Lei C, Xueming H and Ruihang D.
  TITLE     MLN64 deletion suppresses RANKL-induced osteoclastic
            differentiation and attenuates diabetic osteoporosis in
            streptozotocin (STZ)-induced mice
  JOURNAL   Biochem Biophys Res Commun 505 (4), 1228-1235 (2018)
   PUBMED   30322615
  REMARK    GeneRIF: The results suggested that MLN64 played a critical role in
            the meditation of osteoclastic differentiation, and its suppression
            alleviated diabetic osteoporosis in streptozotocin-induced mice.
REFERENCE   4  (bases 1 to 2100)
  AUTHORS   Zhou X, Gao H, Guo Y, Chen Y and Ruan XZ.
  TITLE     Knocking down Stard3 decreases adipogenesis with decreased
            mitochondrial ROS in 3T3-L1 cells
  JOURNAL   Biochem Biophys Res Commun 504 (2), 387-392 (2018)
   PUBMED   29908180
  REMARK    GeneRIF: Stard3 is an essential factor for the 3T3-L1 cells'
            differentiation
REFERENCE   5  (bases 1 to 2100)
  AUTHORS   Lim JM, Lim JC, Kim G and Levine RL.
  TITLE     Myristoylated methionine sulfoxide reductase A is a late endosomal
            protein
  JOURNAL   J Biol Chem 293 (19), 7355-7366 (2018)
   PUBMED   29593096
REFERENCE   6  (bases 1 to 2100)
  AUTHORS   Alpy F, Wendling C, Rio MC and Tomasetto C.
  TITLE     MENTHO, a MLN64 homologue devoid of the START domain
  JOURNAL   J Biol Chem 277 (52), 50780-50787 (2002)
   PUBMED   12393907
REFERENCE   7  (bases 1 to 2100)
  AUTHORS   Tabunoki H, Sugiyama H, Tanaka Y, Fujii H, Banno Y, Jouni ZE,
            Kobayashi M, Sato R, Maekawa H and Tsuchida K.
  TITLE     Isolation, characterization, and cDNA sequence of a carotenoid
            binding protein from the silk gland of Bombyx mori larvae
  JOURNAL   J Biol Chem 277 (35), 32133-32140 (2002)
   PUBMED   12052833
REFERENCE   8  (bases 1 to 2100)
  AUTHORS   Romanowski MJ, Soccio RE, Breslow JL and Burley SK.
  TITLE     Crystal structure of the Mus musculus cholesterol-regulated START
            protein 4 (StarD4) containing a StAR-related lipid transfer domain
  JOURNAL   Proc Natl Acad Sci U S A 99 (10), 6949-6954 (2002)
   PUBMED   12011453
REFERENCE   9  (bases 1 to 2100)
  AUTHORS   Moog-Lutz C, Tomasetto C, Regnier CH, Wendling C, Lutz Y, Muller D,
            Chenard MP, Basset P and Rio MC.
  TITLE     MLN64 exhibits homology with the steroidogenic acute regulatory
            protein (STAR) and is over-expressed in human breast carcinomas
  JOURNAL   Int J Cancer 71 (2), 183-191 (1997)
   PUBMED   9139840
REFERENCE   10 (bases 1 to 2100)
  AUTHORS   Tomasetto C, Regnier C, Moog-Lutz C, Mattei MG, Chenard MP,
            Lidereau R, Basset P and Rio MC.
  TITLE     Identification of four novel human genes amplified and
            overexpressed in breast carcinoma and localized to the q11-q21.3
            region of chromosome 17
  JOURNAL   Genomics 28 (3), 367-376 (1995)
   PUBMED   7490069
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY030024.1, X82457.1 and BC058727.1.
            
            [WARNING] On Nov 22, 2023 this sequence was replaced by
            NM_021547.4.
            
            On Nov 14, 2011 this sequence version replaced NM_021547.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X82457.1, AK041538.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                BY030024.1         2-17
            17-1673             X82457.1           1-1657
            1674-2100           BC058727.1         1761-2187
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 61.75 cM"
     gene            1..2100
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /note="StAR related lipid transfer domain containing 3"
                     /db_xref="GeneID:59045"
                     /db_xref="MGI:MGI:1929618"
     exon            1..141
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            142..414
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..1533
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /note="protein ES 64; protein MLN 64; START
                     domain-containing protein 3; steroidogenic acute
                     regulatory protein related; START domain containing 3"
                     /codon_start=1
                     /product="stAR-related lipid transfer protein 3"
                     /protein_id="NP_067522.1"
                     /db_xref="CCDS:CCDS25345.1"
                     /db_xref="GeneID:59045"
                     /db_xref="MGI:MGI:1929618"
                     /translation="MSKRPGDLACDLERSLPALASLGTSLSHSQSLSSHFIPPPLEKR
                     RAISDVRRTFCLFVTFDLLFISLLWIIELNTNTGIRKNLEQEVIHYSFQSSFFDIFVL
                     AFFRFSGLLLGYAVLRLQHWWVIAVTTLVSSAFLIVKVILSELLSKGAFGYLLPIVSF
                     VLAWLETWFLDFKVLPQEAEEERWYLAAQAAVARGPLLFSGALSEGQFYSPPESFAGS
                     DNESDEEVTGKKSFSAQEREYIRQGKEATAVVDQILAQEENWKFERSNEYGDTVYTIE
                     VPFHGKTFILKTFLPCPAELVYQEVILQPERMVLWNKTVTACQILQRVEDNTLVSYDV
                     SSGAAGGVVSPRDFVNVRRIERRRDRYLSSGIATTHCSKPPTHKYVRGENGPGGFIVL
                     KSANNPRVCTFVWILNTDLKGRLPRYLIHQSLGATMFEFAFHLRQRVGELGARA"
     exon            415..492
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            493..570
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            571..624
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            625..742
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            743..841
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            842..897
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            898..990
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1053
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1149
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1229
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1334
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1428
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..2083
                     /gene="Stard3"
                     /gene_synonym="es64; Mln64"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggggcgggc tcggggggga cgggctcagc ggcggaagta gcgccgccgg gagctctcct
       61 tccgctctga ggagttgcca ggccgtggag cgggactgcg gctgaggcag gaagagtggg
      121 ggccgtggtg acatgaagca gccctgccgc tgaggcccca ttgtctccac ttcaacgtgg
      181 gggcccacca ggatgagcaa gcgacctggt gatctggcct gtgacttgga gcgcagtttg
      241 ccggccctgg cctccctggg cacctcactg tcccacagcc agagcctctc ctcacacttc
      301 atcccgccac ctctggagaa gcgtagggcc atctccgacg tccgccgcac cttctgcctc
      361 ttcgtcacct tcgacctgct cttcatctcc cttctctgga tcatcgagct aaataccaac
      421 actggcatcc ggaagaactt ggagcaggag gtgatccact acagcttcca gagctcgttc
      481 ttcgacatct ttgttctggc tttcttccgc ttctctgggc tgctcctggg ctatgctgtg
      541 ctccgtctcc agcactggtg ggtgattgcg gtcaccacac tggtgtccag tgcattcctc
      601 attgtcaagg tcatcctttc tgagttgctc agcaaagggg cattcgggta cctgctcccc
      661 attgtctctt tcgtcctggc ctggctggag acctggttcc ttgatttcaa agtcttaccc
      721 caggaggctg aagaggagag atggtatctt gctgcccagg ctgctgttgc ccgtggaccc
      781 ctgctgttct ccggtgcttt gtctgagggc cagttctact ctcccccaga atcctttgca
      841 gggtctgaca atgaatcaga tgaggaagtc accgggaaga aaagtttctc tgcccaggag
      901 cgggagtaca tccggcaggg aaaggaagct actgcggtgg tggatcagat cttggcccag
      961 gaggagaact ggaagttcga gaggagtaac gagtatgggg acactgtgta caccattgaa
     1021 gttcccttcc atggcaagac cttcatcttg aagaccttcc tgccctgtcc tgctgagctg
     1081 gtgtatcagg aagtaatcct gcagcctgag aggatggtgc tgtggaacaa gacggtgact
     1141 gcctgccaga tcctacagcg ggtagaggac aacacccttg tctcctatga tgtgtcatcc
     1201 ggagctgcag gtggcgttgt gtcccccagg gactttgtga atgtccgacg tattgagcgg
     1261 cgcagagacc gatacctgtc atccggcatt gccaccacac actgctccaa gccccccacg
     1321 cacaaatatg tcagagggga gaacggcccc ggaggcttca ttgtgctcaa gtcagccaac
     1381 aacccccggg tctgcacctt cgtctggatt cttaacacag atcttaaggg ccgcttgcct
     1441 cggtacctta tccaccagag ccttggggcc accatgtttg aatttgcctt tcacctgcgg
     1501 cagcgtgttg gagagctggg ggcccgagct tgagcatgct cccacgccac cctgcgggcc
     1561 agggttctgt ccactgcctc cggagccaga aagtggaact gtttggcttt cctgctgctc
     1621 atgaaggact ttgtgataag cagaggtggc acctcattcc ctggctgtcg tagtccacta
     1681 agccatactg cccaggaaca gggtcctgag cagttgtggg gttcagtacc tggactcggg
     1741 gtttcccaga ctgaaggagc tgggactgtt ttgcctatgc tgacttctgc cggagactgt
     1801 ctgcatgcct cactgggcat cttagacttg gtcacagagg acctgggctt aggtggggca
     1861 ggagagcttc cgattgccag tgtgaaggtg agggagctct ctaagttttg taccattagt
     1921 gaaggggtct gtgaccctat tccatacaca tcgtggggat acaaggcagg ggacggcact
     1981 gcgctcctgc ctctccgcgc ccttaccctc tacgaaggcc ttcttgggga cctttgtaat
     2041 gatttgagcc aattaaaaac atgaaataaa aaataaaaat gcaaaaaaaa aaaaaaaaaa
//
