LOCUS       NM_011374               8995 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus ST8 alpha-N-acetyl-neuraminide
            alpha-2,8-sialyltransferase 1 (St8sia1), mRNA.
ACCESSION   NM_011374 NM_177276
VERSION     NM_011374.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8995)
  AUTHORS   Fuchigami,T., Itokazu,Y. and Yu,R.K.
  TITLE     Ganglioside GD3 regulates neural stem cell quiescence and controls
            postnatal neurogenesis
  JOURNAL   Glia 72 (1), 167-183 (2024)
   PUBMED   37667994
REFERENCE   2  (bases 1 to 8995)
  AUTHORS   Fuchigami,T., Itokazu,Y., Morgan,J.C. and Yu,R.K.
  TITLE     Restoration of Adult Neurogenesis by Intranasal Administration of
            Gangliosides GD3 and GM1 in The Olfactory Bulb of A53T
            Alpha-Synuclein-Expressing Parkinson's-Disease Model Mice
  JOURNAL   Mol Neurobiol 60 (6), 3329-3344 (2023)
   PUBMED   36849668
REFERENCE   3  (bases 1 to 8995)
  AUTHORS   Tajima,O., Fujita,Y., Ohmi,Y., Furukawa,K. and Furukawa,K.
  TITLE     Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via
            attenuated insulin signaling pathway
  JOURNAL   PLoS One 18 (2), e0281414 (2023)
   PUBMED   36827398
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8995)
  AUTHORS   Meter,D., Racetin,A., Vukojevic,K., Balog,M., Ivic,V., Zjalic,M.,
            Heffer,M. and Filipovic,N.
  TITLE     A Lack of GD3 Synthase Leads to Impaired Renal Expression of
            Connexins and Pannexin1 in St8sia1 Knockout Mice
  JOURNAL   Int J Mol Sci 23 (11), 6237 (2022)
   PUBMED   35682927
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 8995)
  AUTHORS   Araki,E., Hane,M., Hatanaka,R., Kimura,R., Tsuda,K., Konishi,M.,
            Komura,N., Ando,H., Kitajima,K. and Sato,C.
  TITLE     Analysis of biochemical features of ST8 alpha-N-acetyl-neuraminide
            alpha2,8-sialyltransferase (St8sia) 5 isoforms
  JOURNAL   Glycoconj J 39 (2), 291-302 (2022)
   PUBMED   34982351
  REMARK    GeneRIF: Analysis of biochemical features of ST8
            alpha-N-acetyl-neuraminide alpha2,8-sialyltransferase (St8sia) 5
            isoforms.
REFERENCE   6  (bases 1 to 8995)
  AUTHORS   Yamamoto,A., Yamashiro,S., Fukumoto,S., Haraguchi,M., Atsuta,M.,
            Shiku,H. and Furukawa,K.
  TITLE     Site restricted and neuron dominant expression of alpha
            2,8sialyltransferase gene in the adult mouse brain and retina
  JOURNAL   Glycoconj J 13 (3), 471-480 (1996)
   PUBMED   8781978
REFERENCE   7  (bases 1 to 8995)
  AUTHORS   Matsuda,Y., Nara,K., Watanabe,Y., Saito,T. and Sanai,Y.
  TITLE     Chromosome mapping of the GD3 synthase gene (SIAT8) in human and
            mouse
  JOURNAL   Genomics 32 (1), 137-139 (1996)
   PUBMED   8786103
REFERENCE   8  (bases 1 to 8995)
  AUTHORS   Yamamoto,A., Haraguchi,M., Yamashiro,S., Fukumoto,S., Furukawa,K.,
            Takamiya,K., Atsuta,M., Shiku,H. and Furukawa,K.
  TITLE     Heterogeneity in the expression pattern of two ganglioside synthase
            genes during mouse brain development
  JOURNAL   J Neurochem 66 (1), 26-34 (1996)
   PUBMED   8522963
REFERENCE   9  (bases 1 to 8995)
  AUTHORS   Yoshida,Y., Kojima,N. and Tsuji,S.
  TITLE     Molecular cloning and characterization of a third type of N-glycan
            alpha 2,8-sialyltransferase from mouse lung
  JOURNAL   J Biochem 118 (3), 658-664 (1995)
   PUBMED   8690732
REFERENCE   10 (bases 1 to 8995)
  AUTHORS   Yoshida,Y., Kojima,N., Kurosawa,N., Hamamoto,T. and Tsuji,S.
  TITLE     Molecular cloning of Sia alpha 2,3Gal beta 1,4GlcNAc alpha
            2,8-sialyltransferase from mouse brain
  JOURNAL   J Biol Chem 270 (24), 14628-14633 (1995)
   PUBMED   7782326
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC024821.1 and AC122483.5.
            
            On or before Jul 19, 2005 this sequence version replaced
            NM_177276.2, NM_011374.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024821.1, AK046188.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN01164136
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2353              BC024821.1         1-2353
            2354-8995           AC122483.5         47109-53750         c
FEATURES             Location/Qualifiers
     source          1..8995
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 74.78 cM"
     gene            1..8995
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /note="ST8 alpha-N-acetyl-neuraminide
                     alpha-2,8-sialyltransferase 1"
                     /db_xref="GeneID:20449"
                     /db_xref="MGI:MGI:106011"
     exon            1..917
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /inference="alignment:Splign:2.1.0"
     CDS             685..1752
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /EC_number="2.4.3.8"
                     /note="sialyltransferase 8 A; SIAT8-A; ST8SiaI;
                     sialyltransferase 8A; ganglioside GD3 synthase;
                     ganglioside GT3 synthase; sialytransferase St8Sia I;
                     alpha-2,8-sialyltransferase 8A; alpha-2,
                     8-sialyltransferase; ST8Sia I; sialyltransferase St8Sia I"
                     /codon_start=1
                     /product="alpha-N-acetylneuraminide
                     alpha-2,8-sialyltransferase"
                     /protein_id="NP_035504.2"
                     /db_xref="CCDS:CCDS20689.1"
                     /db_xref="GeneID:20449"
                     /db_xref="MGI:MGI:106011"
                     /translation="MSPCGRALHTSRGAMAMLARKFPRTRLPVGASALCVVVLCWLYI
                     FPVYRLPNEKEIVQGVLAQRTAWRTNQTSASLFRRQMEDCCDPAHLFAMTKMNSPMGK
                     SLWYDGELLYSFTIDNSTYSLFPQATPFQLPLKKCAVVGNGGILKMSGCGRQIDEANF
                     VMRCNLPPLSSEYTRDVGSKTQLVTANPSIIRQRFENLLWSRKKFVDNMKIYNHSYIY
                     MPAFSMKTGTEPSLRVYYTLKDVGANQTVLFANPNFLRNIGKFWKSRGIHAKRLSTGL
                     FLVSAALGLCEEVSIYGFWPFSVNMQGDPISHHYYDNVLPFSGYHAMPEEFLQLWYLH
                     KIGALRMQLDPCEEPSPQPTS"
     exon            918..1062
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1172
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1265
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..8995
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8968..8973
                     /regulatory_class="polyA_signal_sequence"
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /note="hexamer: AATAAA"
     polyA_site      8995
                     /gene="St8sia1"
                     /gene_synonym="9330109E03Rik; GD3S; Sia-T; Siat8; Siat8a"
                     /note="major polyA site"
ORIGIN      
        1 caccaatccc ggggcgcgtg tctgcggagt ccagggcgca gcagaaggct gcggcgcacc
       61 gctgaatgaa ctgatgagag agagttctag gtttgcccgt gaggggcgcg gagtgagggt
      121 cctggcgggc gcggccgagg cgccgggggt ggggtagcgg tcccgggcca tcgtggaaat
      181 ttccaaggac ttggtgtggc gcggagagcg catctggggg gtgccgggca ccgcggcggc
      241 gcaggaggcg gggaaagggc ggtgcagggc gcaggagcat ctctttctgg aagggacaca
      301 acccatcaga cgtccgggag ccagccgcgc ctcttccagg accccagccg agggcgacgg
      361 tgatgctgca gtaagggcgg gagccaccgg ccccactgct cttagactcc ttcatcgccc
      421 gctgcctgca gggaaagaga ctaaggcttg tgatttgccc ggaggccact tcctttagca
      481 agacatccca gtaaaagttg cattggcgaa gatccttgta gctgacctct ggggccgtgg
      541 cgtgggggtt ccccagccgt gcgtttgcga gctggaaagc caaaggtgtg tgtgcatggg
      601 gggccggcca ctggagcatc cttcactgcc actttgtcca gcgttgtgct gagggtacac
      661 tgaccctggg acatcgaggc tgcgatgagc ccctgcgggc gggccctaca tacgtccaga
      721 ggggccatgg ccatgctagc tcggaaattc ccgcgtaccc ggctacccgt aggagccagt
      781 gccctctgtg tggtggtcct ctgttggctc tacatcttcc ctgtctaccg gctgcccaac
      841 gagaaggaga ttgtgcaagg ggtgctggca cagcggacgg cttggaggac gaaccagacg
      901 tcagccagtc tcttcaggag acaaatggaa gactgctgtg accctgccca tctctttgct
      961 atgactaaga tgaactcccc catggggaag agcctgtggt acgatgggga gctcttatac
     1021 tcgttcacca tcgataattc cacgtactcc ctcttccccc aggcaacccc cttccagctg
     1081 ccattgaaga aatgtgcggt ggtgggaaac ggtgggattc tgaagatgag tggctgtggc
     1141 cgtcaaatag atgaagcaaa ttttgtcatg cggtgcaacc tgcctccctt gtcaagtgag
     1201 tacaccagag atgtcggttc caaaactcag ttggtgacag ctaaccccag cataattcgc
     1261 cagagatttg aaaacctgct gtggtccaga aagaagtttg tggacaacat gaagatctat
     1321 aaccacagtt acatctacat gcctgccttt tctatgaaga caggcacaga gccgtctctc
     1381 cgtgtgtatt acacactgaa agatgttgga gccaatcaaa cagtgctttt tgctaacccc
     1441 aactttcttc ggaacattgg aaagttctgg aagagtaggg ggatccacgc caagcgcttg
     1501 tctacaggac tctttttggt gagtgcagcc ttgggcctct gtgaggaggt gtccatctat
     1561 ggcttctggc ccttctcggt gaacatgcaa ggggacccta tcagtcacca ctactatgac
     1621 aacgtcttgc ccttctcagg ctaccatgcc atgcctgagg aattccttca gctttggtat
     1681 cttcacaaaa tcggcgcgct gaggatgcag ctggacccgt gtgaggagcc gtcaccacag
     1741 cccacttcct agggactgca gaagaagaaa ggacgggatg ggggatattt ttgctaggtt
     1801 tttttttttt taatgtgact tctaaaaaga actgccaaag tgtgtcatgg attggcatga
     1861 taggaaacaa acaaaaccta agcaaaactg cttttgatgt tggcttggag aacaacaaga
     1921 aataaagtgt cccggggaat gtttttatag tgttgtggat ttgcaagcgg gacaacccca
     1981 aggagacgat gatggcagag cacatgtctg tgattcaaat caagaagatg tgattcgagg
     2041 accagatgaa ctcttgttgc tgaggccgag gggcccatca tggcagcctg tgggagatgc
     2101 tgggatattg ctgactgtca atatacactg gcatcataat cattttaaag atccgtctta
     2161 ttgagactgg cattagaact ataggtttaa aaaaaattat tgttgatttt tgccctgttc
     2221 agggctatgg gtgggtaatg gtatagactt acaaaaccct tcctgctgat tattgtgatt
     2281 tgttaaaaca agtctttgat gactatagtc ccctccacta gtacggtttt aaataagaat
     2341 cacttcttac ctccttttgg ttaagtctac ttagcatgaa gctctgttga gtttagactg
     2401 tgttgatcta ttgtctagat cacacgagcc atttcttcac atcagaagtt gagagggaaa
     2461 ctaaatttta ggtccccatt acatcaaccc attggctctg ttattttcat agaatcacta
     2521 gacctgcaag tacactgttt acttataaag tagcagaagc gccctcatca tttaatgaga
     2581 ggtgacgtag ctcacagaga gtgagagctt catctttaag atagacaaag gcagggcctt
     2641 ttcctctcta acatgaatat ttccttccac gataactcat gcgtgtatac gcatatgtat
     2701 acatgcatgg attatcttgt atacatatat atgtacatat atatgtatac acacatgaat
     2761 atagacacat acactttgac actctctaca ctttctacaa agtaatcaaa gattattctc
     2821 atgaaaccat cagtactgag tgtgcatggc ctagagtctg taaccagtat tggagagcca
     2881 catgtagtgt gggctccatt ccatgttgac acagtcaggc tggcatggca gttgctgtca
     2941 gcttgcctgt cagcacaggg tgcaaggctg accctcaaat acataaatca gaatgtgaac
     3001 ccctctctta ctcatagtgc ctccctgcac cccaaaattt catgaatggg ccctgtgttg
     3061 agcctagtga catgtgatgt ggctctttca aggaagcagg taggaaccac cagccgttta
     3121 agtccttaat gccgagtggg tggggccgtt taagcagctt ggtacatcag ctttgacata
     3181 gctcgggagc tttcctggca gattctggcc cagtgtgctt actgtaggta agggggtgag
     3241 aagggggttc tcttatgacc tttgtgctgt gagatgtgct aagctctgag gagatgtacg
     3301 aacccatttt attttttcaa ctgtcgtcat gatagaggtg aaaacgactc acaagttctg
     3361 cctcatcttg gaggtagaaa ctcggtgtat cgaccatgtc tatgaaaagc agggggcttt
     3421 aaaaggaagg ttaacttaca agacaagcaa gcccctgaga tgtacccttg gggtggggga
     3481 tttccaaaag tgatccaata ttcaggctac tctatggata gcatttgaac tgaggaaact
     3541 gggcggcctg atggtccgct cgctgctgtg cagagctggc ttagtgtttc cgtttgtgtg
     3601 acagcatcag gatatctaga aggcagcatg agctgtgtta ttcgtatctg cgcaaccctg
     3661 actacaatct cgttttgagc tactggtatt taaccattat ctaaggaaga agacatgttc
     3721 atcagtagac ttcatcagaa gtgtaaaagg gctaagaaaa catcacatac aaagatttca
     3781 ttaaagatgt gttcagatga atacattaat tggtcaaaat ctaagcaaga agctcataac
     3841 agaccactgt gcactgagag aactgtctgg gagctttagc tctccatctg gttcctagaa
     3901 caggtccgtg tgtttagtct gtgcagtttt aaagccactc tctatgggat ttgaatgtca
     3961 gaacagatct ggccaacact gtctgtcctt tttacccgag cagactgccc ttccctcagg
     4021 tgccatcagg accccgagga cactttcaat tgttatgacc aagagtgctc acacttgtag
     4081 tagggagtga ccatgaatgc tggtccagta accacaggtc agccccttgc cacagagaat
     4141 gactcagtaa agtgttagtt gtgtgaaggc tgaggaaccc caggctagac caaaaggaaa
     4201 gcttgactgc tcctgtgctc tgtcctttag gccacaggta taacgctgat gtcatgaaca
     4261 ggatctctgt ggcctttcgt tattttatag tgacaattca ctggtatgtc gtatgtaact
     4321 ttatgtgagt ctggttaaat gatgtagcta aacaagtgtg tgtgtgtgtg tgtgtgtgtg
     4381 tgtgtgtgtg tgtgtgtgtg tgtgtctatg tgcatgtatg tgtctatgtg tgtatagctg
     4441 tgtgcatctg tttagcatta tttttagtaa aatatgtgtt cctaagtaga agcctctcca
     4501 gaatcatcct ttagaacatt ctagagtagc accttactct taagagattg ggtattattc
     4561 aatcctgctt attgagattt aggccttcag ctttgggcct agtccactat ttaatgtatt
     4621 tgacctttaa ctttcagctc agaagggatt tgggttatga tagaaatgtt taataggaac
     4681 attaattaat ttcattgtgt ctggcaagag atgacacccc actctaccac caattagatc
     4741 agtgctttaa gtgtgtgtat gtgtgtgtgc acatgcatgt ggaaaataaa attgcttcat
     4801 ggaggaagga gagagaatgc agagactgct aatgaatact caaacaggaa ttctcttttt
     4861 gagtcaaccg cgacttaaga atttgttgat tctcaagctc ccaagtgagg gcggctgctg
     4921 cttgatttta atcacacttc agtaaaaatt aagctaggtg aagagcgagt catcccagca
     4981 gaaggaaagc ttttacatga gagagctttt ctcagaagat gactcttagt gctttgccaa
     5041 agtatatttt taaaaaattg tgtgcctaaa ccagattgtt cacgtttatg actttgaaaa
     5101 aggagggggc acgggagact ctcacccttg aggcctgaat gcccttgcag ggtcctgagt
     5161 tcaggttctg atgcacactt acccacacac agctaactgt tactccaggt ccaggacagc
     5221 tggtgtcctc ctctggtctc catggacact gaatgcaagc aagaacatac acataataaa
     5281 taaatgaatg aataaataaa taaatcttaa taaaggtaga gagttaattc tctaaaatgg
     5341 cagatgttca ggtagtgtcc tttgtgcttc ttcgctggga agccagacat ctatagtttt
     5401 atttttttca tgtttgaaaa taccaagttc atagactctt ccactggcaa atcattgtca
     5461 ggaaagatct aatgagaaaa tcagtcacga gtccactgaa tggtttttac cttataaaat
     5521 acagtgctgt ggtatagatg cttccccaat ggtttttacc ttatgaaata cagtgttgtg
     5581 gtatagacgc ttccccgcca gaaccaggta agattacttc tcatcaaaaa gcccagagat
     5641 caagggctgt aaagctttgt ctgaactctc aagggcaagt ctgcagtaac aaagactgag
     5701 gatgctgttg tgtgtttttt cctgcccaga gtagtcagaa atgtgagctc caggcagccc
     5761 acatcagggg tggaagcaaa ttaacaatgt ttgacacctg cagcccaggt tgatgtggct
     5821 aatcgggtca gcagtaaatc ctcttagaag ttttggaaac ttgattctgt tgtatgctca
     5881 ggagaggaag aggcaaggtg acaagggagg tgaccatagt tcccaagctc tcagcatcca
     5941 cggggacaga ggggtctata cctttgttct tgatgaccct cttgtccaac agaggagctg
     6001 gcttccactg agggctgagc tagaagcccc cactgccact tatctctgcc ctatcacagt
     6061 tgttgtcttc cactgggggc tgagctagta gccttgcaac gacaggagcc tcagcatgaa
     6121 aatttgccaa taatttaaaa ttttgaatca ccaaacatat tttgctttga tttttttttt
     6181 gcctaggatt gcacttgcta atcttgtggc agagtctggt cactgtggcc caggtgtgac
     6241 cctgcatacg atcatacgca gagttctttt ctctgtctat atgggtggac ttccagagtc
     6301 cctgaatcta tggagataac aaatacctca cagttcctgt gctgtgtctt tgaaagtctg
     6361 gaattccgaa gtccagaata tgtctataaa ctcctaaatg tgaggccaca agatttagtc
     6421 tcagccctat acaactcctg ttgtgtaagt gggagagtct tatatctgta catcacacac
     6481 acacacacac acacacacac acacacacac acacgaatag taatagtgtc tagtatctgc
     6541 cttattctca gccttaacat gtcctctgac attttcacac acatcccaga gataaatgat
     6601 tgacacatgg cacaaatgaa aaggttatcc cgactactga accttgctca ctgtaataag
     6661 gacggcatcc cgcgcctcct ccttgttggg gttctcgctg ctgctagcat ttgtagtttc
     6721 ttctgctgtt atggcaaaag aataaataac ataaagaagt gagctgtaat attgtgagca
     6781 tttgaatagc agcccttgac tctcacttgt gggagcacaa aagaagaatt gcattttacg
     6841 gttgcttgtt tatctagacg gtcagtctct ctgttgtgtt aaaagccttc ctggatttgc
     6901 tttatggttg aagctgttgg gactcaatca atgactcaca gttgcttgag agttttatgg
     6961 tgtgatatcc tgcttctgtg taattagagc tcctctggat atctctcact ttcaaatgtg
     7021 tgttatctta gcaactgttt caagatacca ggagatgtgt tgccatgggg tctttcgggt
     7081 taggatgaag agatgaagga tgtggcgtgg actaggcagc tgtatagaga aaactcagag
     7141 gtggtacctg gtttcccatg tgggtctaag cagtcttgga acctccaggt tcctgcctcc
     7201 tccaagcagt gccctcctgg gtgcctgagc ttggtgaaat aaacctacac atatctctct
     7261 gtcacctgcc ttttgagtca tactctcaag atgagttata gtttagtttt cctatcaaga
     7321 tggtgggaaa tgtcaccttg atgttgacca ctggatgtgg ttaccatata cgatgtacac
     7381 agcaagagtt ggtgtcaact tcctgtcccc atgattccca agggaggcca tggcagctta
     7441 gattcattat ccttcatgtt ttagttcaat ctctctctct ctctctctct ctctctctct
     7501 ctctctctct ccctccctcc ctctagaccc cctcccctct tctcctctct ccttccctat
     7561 gttatttttt gcccacagaa tatagaaaag tatattgact tggtagtggg gagtggcaga
     7621 gggtgcctta acttttcctg gctcggctcc ccacttacat agctccctca tgtgtttgtt
     7681 actttgtaga tgtttccatg tctgcccaac ttttacctta atcatcagca aggacccttt
     7741 tacatgtagc aaatgggact gttttataga catttacagt agagtatagg ccttggagaa
     7801 gtctgatgat ggtgtgtaat accctttgct gcattgttga acatttttct aaagtctttt
     7861 aggtgataac tacagaagta ttcctagagt taaggatttc ctggaaaatt ccagtattcg
     7921 tggaagaaag gaaccaacct atcgctgttt tctgttctgt cttcggcact gataggccct
     7981 ctctccacat ttaggatgac tggcggctac cgtagttcac acaaggatct tacacatgag
     8041 aaggggaaag aaaggattca catcacaata ttttaaagcc tgcttcatct ttaacaaatt
     8101 ctgaaacacc gctagactta ggcttatcat gtggcgtagt ttgatctgca aaatattggg
     8161 gaaatatttt tacctttggc ctctttcgtt gtgtattgta gactctaatt ccacacacat
     8221 gaaagctgtt ttatcagtgt aaattttcag aagctggatt agagtaaaaa taggaaaatt
     8281 taaatattct ttctcatgta atgtagtcta ctgatccatg gatataataa ttccgggaga
     8341 gatttttttt agatcacact ataaaattga acctttgatg gatttgcaga gtggcttcct
     8401 cttgctaaag ccaaatttga tgaatagaaa gtgtagggta acccaatgct cgctcgcccc
     8461 tccttccttc cttccttcct tccttccttc cttccttcct tccttccttc cttccttcct
     8521 tcatttctct ctctctctct ttcttcgttc tctctctctc tttctttctt tctctctctc
     8581 ttctttcctt ccttccttcc ttccttcctt ccttccttcc ttccttcctt ccttctttcc
     8641 ttccttcctt ccctccctct ttctttcttt ctttctttct ttctttcttt ctttctttct
     8701 ttctttcttt ctttctcaaa aaaaaaattc acataaaatg cagcaggtaa gaaaaattga
     8761 tttaatcggt attctttatg gtgtgacttg aaaaaaaaat ggtgcctatc tgttggctga
     8821 cacaaacaat gatgtgccca agggaggtca ctgggaaaat gtcttttctt tcgtgtgttc
     8881 ctgagtggtg tggcagtgag gagatttaac caagtctcag tttctctacc tcccttcctt
     8941 ggagaatatt tggaaacgta ccctgtgaat aaaatggctt ttttttttca acgaa
//
