LOCUS       NM_153091               5739 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus suppression of tumorigenicity 7-like (St7l),
            transcript variant 1, mRNA.
ACCESSION   NM_153091
VERSION     NM_153091.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5739)
  AUTHORS   Hooi,C.F., Blancher,C., Qiu,W., Revet,I.M., Williams,L.H.,
            Ciavarella,M.L., Anderson,R.L., Thompson,E.W., Connor,A.,
            Phillips,W.A. and Campbell,I.G.
  TITLE     ST7-mediated suppression of tumorigenicity of prostate cancer cells
            is characterized by remodeling of the extracellular matrix
  JOURNAL   Oncogene 25 (28), 3924-3933 (2006)
   PUBMED   16474848
REFERENCE   2  (bases 1 to 5739)
  AUTHORS   Ficker,M., Powles,N., Warr,N., Pirvola,U. and Maconochie,M.
  TITLE     Analysis of genes from inner ear developmental-stage cDNA
            subtraction reveals molecular regionalization of the otic capsule
  JOURNAL   Dev Biol 268 (1), 7-23 (2004)
   PUBMED   15031101
REFERENCE   3  (bases 1 to 5739)
  AUTHORS   Saitoh,T. and Katoh,M.
  TITLE     Molecular cloning and characterization of mouse St7r (St7-like,
            St7l)
  JOURNAL   Int J Mol Med 10 (1), 119-123 (2002)
   PUBMED   12060862
  REMARK    GeneRIF: the first report on molecular cloning and initial
            characterization of mouse St7r
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK030273.1, BC058781.1, AC166156.4 and AI834981.1.
            
            On Dec 1, 2011 this sequence version replaced NM_153091.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC058781.1, AK033865.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-575               AK030273.1         504-1078
            576-2501            BC058781.1         1-1926
            2502-5216           AC166156.4         115416-118130       c
            5217-5739           AI834981.1         1-523               c
FEATURES             Location/Qualifiers
     source          1..5739
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 45.88 cM"
     gene            1..5739
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /note="suppression of tumorigenicity 7-like"
                     /db_xref="GeneID:229681"
                     /db_xref="MGI:MGI:2386964"
     exon            1..803
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     CDS             590..2269
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /note="isoform 1 is encoded by transcript variant 1;
                     suppressor of tumorigenicity 7 protein-like; ST7-related
                     protein; tumor suppressor ST7 like"
                     /codon_start=1
                     /product="suppressor of tumorigenicity 7 protein-like
                     isoform 1"
                     /protein_id="NP_694731.1"
                     /db_xref="CCDS:CCDS17705.1"
                     /db_xref="GeneID:229681"
                     /db_xref="MGI:MGI:2386964"
                     /translation="MADGDYFAEAARAVGCPHAPVPGLGLGPPLGWKERLKAGLANSG
                     STLWFLAGLGLLYALRVPLRLCDNVTAVTGFLSSLTPKFYVALTGTSSLISGLIFIFE
                     WWYFHKHGTSFIEQVSISHLRPLMGGTESSISEPGSPANSRESETLRHHHLSECKVWR
                     NPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDHQTFFTCETDFLRPSDTVMQKAWR
                     ERNPPARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERLFKQALRAGEIIYRRSQ
                     QCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLN
                     IHENLLESLLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKTRTVSDKFSPETAF
                     RKGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHL
                     QHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHHVSVY
                     PKKELPFFIHFTAGLCSSTAMLAFLTHQFPEVMGVFAKAVSMISRTCVEYL"
     exon            804..886
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1052
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1053..1107
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1223
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1302
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1457
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..1555
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1556..1670
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1671..1743
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1846
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..1997
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2090
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     exon            2091..5725
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2477..2482
                     /regulatory_class="polyA_signal_sequence"
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /note="hexamer: AATACA"
     regulatory      2496..2501
                     /regulatory_class="polyA_signal_sequence"
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /note="hexamer: ACTAAA"
     polyA_site      2501
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /note="major polyA site"
     polyA_site      2522
                     /gene="St7l"
                     /gene_synonym="St7r"
     polyA_site      2574
                     /gene="St7l"
                     /gene_synonym="St7r"
     regulatory      5681..5686
                     /regulatory_class="polyA_signal_sequence"
                     /gene="St7l"
                     /gene_synonym="St7r"
                     /note="hexamer: TATAAA"
     polyA_site      5720
                     /gene="St7l"
                     /gene_synonym="St7r"
ORIGIN      
        1 agttccgcgc gggtgtgaca gcctggagtc ggcgctctag gaagtcggct tgcccctcgg
       61 ggctttgcag ccttaacatc tttctccctg agttccggtc actttcccat tcgtcctgga
      121 gtgcttggtg gcgggcctcg actcttgcgt ggcgtctggg ctccctctgg tcatggagca
      181 gttgctacac ctctaagttt ttctgatccg gttggtctcc tgggccgccg agtccagggc
      241 actaagagct gctcggctct ttgagacatc agtacttttc cgaccccggc acagggcgac
      301 aggttaccct caaccacgta tggaagaaaa accacttccc tccggcgcca cactgagtcc
      361 gtttccagaa gaataagcgc caccatcaga tgcttccccg ccctcctaga ggactaggta
      421 gcccctcagt cggccaccgc gctccgccac cttccagatc tccagccagt tccccaggac
      481 tcagcctaga cagaggccag cttcaagtcc gccactatcc caggattccc gactccgggt
      541 ttccggccct tctcccctcc caggtcccgg cgcctgccgg agccgcaaga tggcggacgg
      601 agactacttc gcggaagccg cgcgggccgt ggggtgtccc catgcacctg ttcctggctt
      661 gggcctgggc ccgccgctgg gctggaaaga gcggctgaag gccgggttgg cgaactctgg
      721 gtccacgctg tggttcctgg cggggctggg gctgctttac gctctgaggg tcccgctgag
      781 gctgtgtgac aacgtgacag cggtgacagg gtttttaagt tcactgacac ccaagttcta
      841 tgtggcactt acagggacat cttctttgat atctggacta atatttatat ttgaatggtg
      901 gtacttccat aagcatggta catcttttat tgaacaagtg tccataagcc atttgcggcc
      961 actgatggga ggaacagaga gtagcatttc agagccgggc tctcctgcca acagcagaga
     1021 aagtgaaacc ctcagacacc accatctatc agaatgcaag gtctggagaa accctttaaa
     1081 cctcttcaga ggagcagaat acagaagata cacttgggtg actggtaaag agccacttac
     1141 ttactatgac atgaacttgt ctgcccagga tcaccagacc tttttcacct gtgaaacaga
     1201 ctttttacgt ccttcagaca cagttatgca gaaggcatgg agggaaagaa atcctccagc
     1261 tcgaatcaaa gcagcctatc aagctttaga gttaaacaat gactgtgcca ctgcctacgt
     1321 cctactggcc gaagaagaag caacaaccat tgtagatgct gaaaggttgt ttaaacaggc
     1381 actcagggca ggagagataa tttatagacg gtcacagcaa tgccagcacc agagccctca
     1441 gcatgaagct caactgaggc gagataccaa tgtacttgtg tatattaaaa gaagattggc
     1501 catgtgtgcg agaaaattgg gaagaataag agaagcagtg aaaataatga gagatttgat
     1561 gaaagaattt cctcctctta ccatgttgaa catccatgaa aatcttttag aatcacttct
     1621 agaattgcag gcctatgcag atgttcaggc agtcctggca aaatatgatg atataagcct
     1681 tccaaagtca gcggccatct gctacacagc agcactactg aaaacaagaa ccgtctcaga
     1741 taaattctct ccagaaacag ccttcagaaa agggttaagc acagcagaaa ttaatgctgt
     1801 ggaagcaatt catagagctg tggaatttaa tcctcatgtt ccaaaatact tactagagat
     1861 gaaaagttta atcttacctc cagaacacat tctgaagcga ggagatagcg aagcaattgc
     1921 ctatgctttc tttcatctac agcactggaa acgaatagaa ggtgctctga atctcctgca
     1981 gtgtacatgg gaaggcactt ttagaatgat tccataccca ttagagaaag gacatctatt
     2041 ttacccttat cccagctgca cagagactgc tgatagagag ctattgccta ctttccatca
     2101 cgtctctgtc tatccaaaga aggagcttcc ttttttcatc cactttacag caggactgtg
     2161 ctcctctacc gcaatgctag cgtttctcac tcaccagttt cctgaagtca tgggtgtttt
     2221 tgctaaagct gtgagtatga tctccaggac ttgtgtggag tatttataaa ccagcgcagg
     2281 aaagcatctc tcatctgcca gtgctaaccc gcacgagcag cggaagacac ttgtagacgg
     2341 caagagctga tgtaaagctt ctaccatgac tgtgtcaaac acaagctctg gtgatgtgaa
     2401 cttctatcgc ttaaacgttt aagagtacaa tgctataaca ttataaaatt ggcctttgtg
     2461 attaattttg gtgattaata caacattcct taccaactaa agaatgatac aatttttctt
     2521 tatcactagt gtattttctt tggtatttaa aaactactaa ttttgtaaac aaaactttga
     2581 cttttccatt gaaatgatgt cacgagttca aaacatttac tgactttaac tcaagagtga
     2641 aactatagtg gggaataagt gcatagaagg cacaggaggg acatttcacc atgcgtggca
     2701 tgtgcttctt ggctcaaagg ttctcctagt ttttgcatcc tttcattgac cctttcaggt
     2761 tctggcctta agtatagact gtgtgtcagc ctttatttta attcaaaccc ttcaattttg
     2821 aattggtttc ctctttcctg accaaggact attttttttt ccttccttcc ttccttcctt
     2881 ccttccttcc ttccttcctt ccttccttcc ttccttcctt cctctcttta ctctttctgt
     2941 ctgtctgtct gtctgtctgt ctgtttattt aatttatttt gaggcaagat ttctctgtgt
     3001 agccctggct gttctggagc tcactctgta gaccaggctg gccttgaact cagaaatctg
     3061 cctgcctctg cctcccaagt gcagggatta aaggcgagca gcaccattgc ctggctgagg
     3121 actgatattt aaaatggttc ccctatttat tctttaatat taatatgtta attcatgtca
     3181 caaaattttt tatttaataa tttttcattt taataattta catattttta tgcaattttt
     3241 gaggggtggc aagatgtttc agcaggtaaa gtacttgttg ctaagcttaa tctaagtgat
     3301 ctaagttcga actcatataa gggtgggaga gagccaagtt tagaaagttg ttctctcact
     3361 ttcacacaca tgccatgatg aatgtgtccc caggatcatg caaacacaat catcataaat
     3421 taaacataag caaataaata aaaatatatc tcccttttac agcctagcat tatcaccagg
     3481 caatgggtga ggatccaaaa gaaagtgctg ttttgttata ttctcaaata ttcaggaata
     3541 aataaatata gaaacacata tttaatttgt atggaataat taatatgtat ttctatattt
     3601 atttattcca ttataactcc ttgtttttct catagtttct tttcctggca tgagaatagt
     3661 ttattctgag ccaggccatg gtgttgcatg cctttaatcc cagcacttgg gaggcagagg
     3721 caggggatct ctattgagtt caagaacagc ctgatccaca gagtgagttc caggacagcc
     3781 agagctacac agagaaaccc tgtctgagag gtattgagat gtgagggggt caacaacaac
     3841 agaacccaaa agaactagtc tattttgtgc cttgcagatg tgttggctct tacggcacca
     3901 gtgctatgga cactggctcc ctttgccttg gaggtcacct gtgcaatgtg ttaagatgtc
     3961 actggctcta ggcctaatag tctaggccta atagtacgaa tttgattttt agttaggctc
     4021 caagacaaat gacttccaac tgctgctcag ggagtgtggg tgtgtgggtt gcagactgac
     4081 tattccattc cctcctaatg gggaaaggaa acttggtaat gacttttact gttgcttgta
     4141 gtggtgctga tggggaataa gtgtgtctca gactaacatg acctcactgt gtgagaggca
     4201 tggacaaatg gaccaaaaag gggatcctgt tcacttagag gagaggaaga aaagaagtgg
     4261 ggaggcactt aacccacata tatgaacgat ccagacaggc aacgagagag atgggttctt
     4321 gaatttttct caaggcaatg gagtaggaag ggggagaaat agagcaggtc tgcaatctgc
     4381 aacaaagatg gagcagtcaa tagtgtattt ccctgaagtt ctagctaaca gggagtagag
     4441 agtgctctac tttctatcca tcaatgttca tatagtcgtg gccttcgatg acgaggtcac
     4501 taatggcacc tggagagcag taaggttaca cagcgcaggt tgcttagcac tcttagcaga
     4561 gacgcgagaa tgaaaaattg cacctttgaa agtagaagct tccttttttt ttagaccaaa
     4621 agttactaat atattattat tttagttgct agataacaaa catttatata ctatatttta
     4681 tttgtatagt tggtgatata taatatttaa aagcttgctg acagtgaact tttatagcta
     4741 tcttttatcc ctgtgggtat tacatgtata ttttttgatt tctgaaagcc acatacttac
     4801 tgatgagact tgcacatcag tatgtggtat gcagctattc taaagtcagg tcctatgtaa
     4861 gagtcagtgg aaagtgattg ggcagtctgc ccctcacagt gtgcaacact taaatgcttc
     4921 cacagaagac atgcaacaag gaactggagg ctccttttct agtttttcac cacttcataa
     4981 catatggtct atgcacgaga aacaccaccc tcttgtagga gcatgttaag aaaggatcgg
     5041 ctcaggcttc gctgcagagt ctgaatcaga gtctgagtcc taacaagatc cccagcttat
     5101 cctgcatgca cttttaaagc tcaagaagcc tccttccacc accaccacca gttattctgg
     5161 ccaccaatgc gaggaattgg aacaccagga tagcatgctg ccttatcggg ctggagaagt
     5221 ggctgccctg cagagtgctt atgagcaaga ctctggaacc aaactgcttt gctctgatcc
     5281 cagctctgac accgcctatg caacctcatg taagttatgc aatcttctct agtcttcgtt
     5341 gtaaagtaag aaatagtgct acataggtgt tgttggggta aatgtgttta acgtatatca
     5401 actgtgtaga actattcctc cacagtaaga agtaagtgga tattattccc tctgattgca
     5461 aatgatgtta ccactaaaga gagcctacct cttatgagga taacaagtgc aaaatgagtt
     5521 ttcccacagt aattggaata taatgatagc tggatgtcat ttaaataata agaatataca
     5581 actgatacat catgtgtgtg tgaaccacaa aaagagggga aaatgtttcc aattcttggt
     5641 tctggcaaac tgttgtttag aacagaacat tttggcaagt tataaaccgt cagattatga
     5701 caatataaag taaaagctga tgaaaaaaaa aaaaaaaaa
//
