LOCUS       NM_001418649            3280 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus suppression of tumorigenicity 13 (St13), transcript
            variant 2, mRNA.
ACCESSION   NM_001418649
VERSION     NM_001418649.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3280)
  AUTHORS   Cao,R.C., Yang,W.J., Xiao,W., Zhou,L., Tan,J.H., Wang,M.,
            Zhou,Z.T., Chen,H.J., Xu,J., Chen,X.M., Jin,Y.C., Lin,J.Y.,
            Zeng,J.L., Li,S.J., Luo,M., Hu,G.D., Jin,J., Yang,X.B., Huo,D.,
            Zhou,J. and Zhang,G.W.
  TITLE     St13 protects against disordered acinar cell arachidonic acid
            pathway in chronic pancreatitis
  JOURNAL   J Transl Med 20 (1), 218 (2022)
   PUBMED   35562743
  REMARK    GeneRIF: St13 protects against disordered acinar cell arachidonic
            acid pathway in chronic pancreatitis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3280)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   4  (bases 1 to 3280)
  AUTHORS   Hughes,D.S., Keynes,R.J. and Tannahill,D.
  TITLE     Extensive molecular differences between anterior- and
            posterior-half-sclerotomes underlie somite polarity and spinal
            nerve segmentation
  JOURNAL   BMC Dev Biol 9, 30 (2009)
   PUBMED   19463158
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3280)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109153.13.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14777535.550998.1,
                                           SRR7345562.3279929.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-289               AC109153.13        131793-132081
            290-492             AC109153.13        132183-132385
            493-550             AC109153.13        139548-139605
            551-623             AC109153.13        142147-142219
            624-694             AC109153.13        143470-143540
            695-761             AC109153.13        148824-148890
            762-846             AC109153.13        153870-153954
            847-957             AC109153.13        154072-154182
            958-1060            AC109153.13        156964-157066
            1061-1177           AC109153.13        160296-160412
            1178-1226           AC109153.13        162428-162476
            1227-1369           AC109153.13        165381-165523
            1370-3280           AC109153.13        166292-168202
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 38.07 cM"
     gene            1..3280
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /note="suppression of tumorigenicity 13"
                     /db_xref="GeneID:70356"
                     /db_xref="MGI:MGI:1917606"
     exon            1..289
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            290..492
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     CDS             383..1498
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /note="isoform 1 is encoded by transcript variant 2;
                     hsc70-interacting protein; protein ST13 homolog; Hsp70
                     interacting protein"
                     /codon_start=1
                     /product="hsc70-interacting protein isoform 1"
                     /protein_id="NP_001405578.1"
                     /db_xref="GeneID:70356"
                     /db_xref="MGI:MGI:1917606"
                     /translation="MDPRKVSELRAFVKMCRQDPSVLHTEEMRFLREWVESMGGKVPP
                     ATHKAKSEENTKEEKRDKTTEENIKTEELSSEESDLEIDNEGVIEPDTDAPQEMGDEN
                     AEITEEMMDEANEKKGAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKL
                     QKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEAAHDLALACKLDYDEDASA
                     MLREVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEHERAQREEEARRQSGSQ
                     YGSFPGGFPGGMPGNFPGGMPGMGGAMPGMAGMAGMPGLNEILSDPEVLAAMQDPEVM
                     VAFQDVAQNPSNMSKYQSNPKVMNLISKLSAKFGGQS"
     exon            493..550
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            551..623
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            624..694
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            695..761
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            762..846
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            847..957
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1060
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1177
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1226
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1369
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..3280
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1850..1855
                     /regulatory_class="polyA_signal_sequence"
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /note="hexamer: AATAAA"
     polyA_site      1904
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /note="major polyA site"
     regulatory      3257..3262
                     /regulatory_class="polyA_signal_sequence"
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /note="hexamer: AATAAA"
     polyA_site      3280
                     /gene="St13"
                     /gene_synonym="1110007I03Rik; 3110002K08Rik; HIP; HOP;
                     HSPABP; HSPABP1; p48; PRO0786; SNC6"
                     /note="major polyA site"
ORIGIN      
        1 gtcactcggc taggttttgg gcgcgccggc cccacgggca tttatttatt ttcccccctc
       61 ctccatgcgg cgtctcgttc tgcttaatgc ccatcttcac agaagaaata tcttattcca
      121 aatgtctccc tatgtcccgc ttgaaagcgc acagacacaa ggtccttcat ccatcccggg
      181 gaattaggtc agaggaaaga atccgagtga gactgttcgc cgatcgaagc aggcattgtc
      241 acgggcagct acacttctag aaggttctag gcggagcaca ggtccagagc cgcccccttc
      301 cacttggtca cgttgagccg ctcccgggcc tggcatcgtg cctccgcagc cgcccaccgc
      361 cttcagcttc cagcctccca ccatggatcc ccgcaaagtg agcgagcttc gggccttcgt
      421 gaagatgtgt aggcaggacc cgagcgtcct gcacaccgag gaaatgcgct tcctgaggga
      481 gtgggtggag agcatggggg ggaaagtacc acctgctact cataaagcta agtcagaaga
      541 aaacaccaag gaagaaaaaa gagacaagac gacagaggaa aacataaaga cagaggagct
      601 atcaagcgag gagagcgatc tagaaattga caatgaaggt gtaattgaac cagacactga
      661 tgcccctcag gaaatgggag atgaaaatgc agagataacc gaggagatga tggatgaagc
      721 aaatgagaag aagggggctg ccattgaagc cctaaatgat ggtgagctcc agaaagccat
      781 tgacttgttc acagacgcca tcaagctaaa tcctcgcttg gctattctgt acgccaagag
      841 agccagtgtc tttgtcaaac tacagaagcc aaatgctgcc atccgagact gtgacagagc
      901 cattgaaata aaccctgatt ccgctcagcc atacaaatgg cgagggaaag cacacagact
      961 cttgggtcac tgggaggaag cagctcatga ccttgccctt gcctgtaaac tggattatga
     1021 cgaggatgcc agtgcaatgc tgagagaagt ccaacctcgg gctcaaaaaa ttgctgaaca
     1081 tcggagaaag tatgagcgaa aacgtgaaga gcgagagata aaagaacgga tagaaagggt
     1141 gaagaaggct cgagaagagc atgagagagc ccaaagggaa gaagaagcca gaagacaatc
     1201 cggatctcag tatggctctt ttccaggtgg ttttcctggg ggaatgcctg gtaattttcc
     1261 tggaggaatg cctggaatgg gaggggccat gccaggaatg gcagggatgg cagggatgcc
     1321 tggactcaac gaaatcctca gtgatccaga ggttcttgca gccatgcagg atccagaagt
     1381 catggtggct ttccaggatg tggcccagaa cccatcaaat atgtcaaaat atcagagcaa
     1441 cccgaaggtt atgaatctca tcagtaaatt gtcagccaag tttggaggcc aatcgtaatg
     1501 tcaaagccct tgctgaatga agaacagctt agctcacttc ctggatgttg caataataca
     1561 aaccagtgta cctctgacct caccgggaga gctggggcgc ttcgaagata atccctaccc
     1621 tctacatcaa atgcggctga ggcattttac agtggtttgc cattagcgtg ttcattcaga
     1681 taatgttttc ttactaggaa ttacaaactt aaaacatttt tcaaccttta acatattttg
     1741 taaaaactta ggggagtcaa ttcctccatt tttctttact aacttgggct tttccttttg
     1801 aattactggg cagggaggtg agtggatgac ttaatgattt catgaatgaa ataaagattt
     1861 gttagtggga agcaaataaa acacattaag ttgattgagt tggacatacg gttcctgaag
     1921 tatcttgatt tgtgtttttt tttttttaat gttttatttc aaaatgatct atttcagtaa
     1981 atctcttggg accaccagta tttggatctg accttggtag gactaaagta ttgggcagag
     2041 cagcagcagt cccaggtttt gtttgacctg tgtaggctgc atttaaatct ttaaaactgc
     2101 tttggtgtcg tttttttttt tttttttttt tttaagtgtt acagcttccc ctagattaca
     2161 tagctctgct gttgtccatt gtttcaaata aatgttctgt agcattccca catagagaaa
     2221 aagagtgctt tctgtttttg tcagaaatga cctttcctat tagaaaatgc cctgtctgct
     2281 tgtcaccctc tgaatcttct tgagctacag gtagtgtttt cagtaccatc atcacttctg
     2341 tcactcacag cataattgtg gaagcagatt cattgctagt ttagtttcat atataatata
     2401 tacagtaatt gtagggtcat acctcaaatg ctggtatctt acttggccat ggggttgctt
     2461 gtttaaatat taaacttacc cttgtgacct ctgtccacag tcatttgaag gaaggatttc
     2521 ctttggtttt agctatgctt atgaaattga gaaacaattg caatgttaag agtttatgtg
     2581 aagtatacat ctttgtactt ggaagagtct aagttgttta tatttggtaa aaggttcatt
     2641 tgtccctttt agctcttaaa tatctcgatg tatttaatgc cttgttttct ctcctgccgc
     2701 aggataaaga aaatgataaa cccacaaagt gcatatttca aatagcatat atctgaaatc
     2761 gtatgtctgt gcaggtttaa ctgctgcata cagcgggcac agatgcatct tgttacatgt
     2821 aagaaaaagc tgtatttgaa cagagcatgc gtttaaagcc cttaacaaat tcatcacata
     2881 atcttaaatt ggaactttgc acggttctta gtccaagtgt gctctccttt catacagttt
     2941 ccatggtgtg agtgctttac tgaagatctg tttcttttgt actctgacta cacatgaccc
     3001 aattatattc taatgtgaaa atattagcat aaataggtga aattgctctt ctgaaaattg
     3061 tgtcctgtgc ttttagactt tggagttcca cagatagtaa aaatatagcc ttcacaattt
     3121 tttaataatc agtatcattt ctacaccaaa atattgtttt tttccctcac taaagacaat
     3181 ataaagaaaa ataatctaag aagataaagg ggctttctgc ttaaagatat gtagataata
     3241 ttcctaagta tgctgaaata aaatactgtt tcaaactgga
//
