LOCUS       NM_175525               1321 bp    mRNA    linear   ROD 06-FEB-2024
DEFINITION  Mus musculus ssu-2 homolog (Ssu2), transcript variant 1, mRNA.
ACCESSION   NM_175525 XM_001001594 XM_973398
VERSION     NM_175525.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1321)
  AUTHORS   Xiong,F., Ji,Z., Liu,Y., Zhang,Y., Hu,L., Yang,Q., Qiu,Q., Zhao,L.,
            Chen,D., Tian,Z., Shang,X., Zhang,L., Wei,X., Liu,C., Yu,Q.,
            Zhang,M., Cheng,J., Xiong,J., Li,D., Wu,X., Yuan,H., Zhang,W. and
            Xu,X.
  TITLE     Mutation in SSUH2 Causes Autosomal-Dominant Dentin Dysplasia Type I
  JOURNAL   Hum Mutat 38 (1), 95-104 (2017)
   PUBMED   27680507
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK085578.1.
            
            On Apr 5, 2007 this sequence version replaced NM_175525.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK085578.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1321              AK085578.1         2-1322
FEATURES             Location/Qualifiers
     source          1..1321
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 52.2 cM"
     gene            1..1321
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /note="ssu-2 homolog"
                     /db_xref="GeneID:243612"
                     /db_xref="MGI:MGI:2443733"
     exon            1..52
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..1047
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     protein ssu-2 homolog; protein SSUH2 homolog"
                     /codon_start=1
                     /product="protein SSUH2 homolog isoform 1"
                     /protein_id="NP_780734.1"
                     /db_xref="CCDS:CCDS20405.1"
                     /db_xref="GeneID:243612"
                     /db_xref="MGI:MGI:2443733"
                     /translation="MDRDPSEEDSMADLSFEAESPVLPPDELLEGLPSYDWLLQGRER
                     QVFFPPLEALGRSQEPACWSSVLEHSRVPVVTEEVAREALLSFVNSHCCYSSAAAGNL
                     IIQELRQQTLCRYRLETFSESRVSEWTFQPVTNHSVDGPQRGTSPRLWDMKVQVPPMF
                     QEDTRKLQVPHSSLVKECHKCHGRGRYKCSGCHGAGMVRCSSCSGTKRKAKQPRRCHL
                     CSGSGRRRCSTCSGRGNKTCATCKGERKLEHFVQLVIMWKNSLFEFMSPHHLHCPKEL
                     LAKARGENLFRDENATVYPIVDFPLQDISLASQRGIEEHSTMLASRARILQQMFFYSG
                     GPFHHS"
     exon            53..151
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            152..233
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            234..366
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            367..427
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            428..552
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            553..615
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            616..701
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            702..794
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            795..900
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            901..1008
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1321
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1321
                     /gene="Ssu2"
                     /gene_synonym="D630042P16Rik; Fls485; Ssuh2"
                     /note="putative"
ORIGIN      
        1 gttacttggc tggacgcctc gaccatggac agggacccga gtgaggagga cagcatggct
       61 gacctcagct ttgaggctga gagtcctgtg ttgccccctg atgagctcct ggaggggttg
      121 cccagctatg actggcttct tcaagggcgt gaaaggcagg tcttcttccc gcccttggag
      181 gccctgggga ggtcccagga gcctgcgtgt tggtcttcag tcctggagca cagcagagtc
      241 cctgtggtga ccgaggaggt ggcccgtgag gccctactca gcttcgtgaa ctcccattgc
      301 tgttacagca gtgcagctgc tggcaacctc atcattcagg agctgaggca gcaaaccctc
      361 tgcaggtatc gtctggagac cttcagcgaa tccagagtca gcgagtggac atttcagcct
      421 gtaaccaacc actcggtgga cggaccacag agaggcacct cccccaggct ttgggatatg
      481 aaggtccagg tgcctccgat gtttcaggaa gacaccagaa agctccaagt gccccactcc
      541 tccctggtca aggaatgtca caaatgccac gggcgtggtc gctacaagtg cagcggctgc
      601 catggggctg gcatggtgag gtgttcatcc tgcagtggca ccaagcgcaa agccaagcag
      661 ccccggagat gccacctgtg ttctggctct ggccgacgca ggtgcagtac gtgctctggg
      721 agaggcaaca agacatgcgc cacctgcaag ggggagagga agctggagca ctttgtccag
      781 ctggtcatca tgtggaagaa cagcctgttt gagtttatgt ccccacacca cctccactgc
      841 cccaaggagc tgcttgccaa agccagaggg gaaaacctct tcagggatga gaatgccacg
      901 gtatacccca ttgtggattt ccccctgcaa gacatctctt tggcctccca gaggggcatt
      961 gaggaacaca gtaccatgct ggcttcccgt gctcgcatcc ttcagcagat gtttttctac
     1021 tctgggggcc cctttcacca ctcctaggaa agtgacatga tgaccttgga cttgagttcc
     1081 aaggaatgct gaagaatttt ggcagcttga tggtatgttg gtgccaggca cttggtaaag
     1141 ccaccacatc ttgaattcac tcatctgccc cacagcttcc tctgagggat gcctgtgaag
     1201 ccagctgcct ttggagaata tacagaagac atagggaagg gtttctgatg tgtggtgggc
     1261 acacagtaga tgggaagccc tggagccctg agtcggtgca ggccattaaa acaaaatcac
     1321 t
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