LOCUS       NM_182990               2858 bp    mRNA    linear   ROD 10-MAR-2023
DEFINITION  Mus musculus structure specific recognition protein 1 (Ssrp1),
            transcript variant 1, mRNA.
ACCESSION   NM_182990
VERSION     NM_182990.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2858)
  AUTHORS   Wang QS, Fan KJ, Teng H, Chen S, Xu BX, Chen D and Wang TY.
  TITLE     Mir204 and Mir211 suppress synovial inflammation and proliferation
            in rheumatoid arthritis by targeting Ssrp1
  JOURNAL   Elife 11, e78085 (2022)
   PUBMED   36511897
  REMARK    GeneRIF: Mir204 and Mir211 suppress synovial inflammation and
            proliferation in rheumatoid arthritis by targeting Ssrp1.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2858)
  AUTHORS   Chen F, Zhang W, Xie D, Gao T, Dong Z and Lu X.
  TITLE     Histone chaperone FACT represses retrotransposon MERVL and
            MERVL-derived cryptic promoters
  JOURNAL   Nucleic Acids Res 48 (18), 10211-10225 (2020)
   PUBMED   32894293
  REMARK    GeneRIF: Histone chaperone FACT represses retrotransposon MERVL and
            MERVL-derived cryptic promoters.
REFERENCE   3  (bases 1 to 2858)
  AUTHORS   Sandlesh P, Safina A, Goswami I, Prendergast L, Rosario S, Gomez
            EC, Wang J and Gurova KV.
  TITLE     Prevention of Chromatin Destabilization by FACT Is Crucial for
            Malignant Transformation
  JOURNAL   iScience 23 (6), 101177 (2020)
   PUBMED   32498018
REFERENCE   4  (bases 1 to 2858)
  AUTHORS   Piquet S, Le Parc F, Bai SK, Chevallier O, Adam S and Polo SE.
  TITLE     The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling
            and Repair of DNA Damage
  JOURNAL   Mol Cell 72 (5), 888-901 (2018)
   PUBMED   30344095
  REMARK    GeneRIF: It has been demonstrated that FACT potentiates
            H2A.X-dependent signaling of DNA damage.
REFERENCE   5  (bases 1 to 2858)
  AUTHORS   Elsen GE, Bedogni F, Hodge RD, Bammler TK, MacDonald JW, Lindtner
            S, Rubenstein JLR and Hevner RF.
  TITLE     The Epigenetic Factor Landscape of Developing Neocortex Is
            Regulated by Transcription Factors Pax6--> Tbr2--> Tbr1
  JOURNAL   Front Neurosci 12, 571 (2018)
   PUBMED   30186101
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2858)
  AUTHORS   Gariglio M, Ying GG, Hertel L, Gaboli M, Clerc RG and Landolfo S.
  TITLE     The high-mobility group protein T160 binds to both linear and
            cruciform DNA and mediates DNA bending as determined by ring
            closure
  JOURNAL   Exp Cell Res 236 (2), 472-481 (1997)
   PUBMED   9367632
REFERENCE   7  (bases 1 to 2858)
  AUTHORS   Souslova V, Ravenall S, Fox M, Wells D, Wood JN and Akopian AN.
  TITLE     Structure and chromosomal mapping of the mouse P2X3 gene
  JOURNAL   Gene 195 (1), 101-111 (1997)
   PUBMED   9300827
REFERENCE   8  (bases 1 to 2858)
  AUTHORS   Pilon AL, Kozak CA, Nebert DW and Puga A.
  TITLE     Localization of the murine Hmg1 gene, encoding an HMG-box protein,
            to mouse chromosome 2
  JOURNAL   Mamm Genome 4 (10), 612-614 (1993)
   PUBMED   8268661
REFERENCE   9  (bases 1 to 2858)
  AUTHORS   Huppi K, Siwarski D, Shaughnessy J Jr, Klemsz MJ, Shirakata M, Maki
            R and Sakano H.
  TITLE     Genes associated with immunoglobulin V(D)J recombination are linked
            on mouse chromosome 2 and human chromosome 11
  JOURNAL   Immunogenetics 37 (4), 288-291 (1993)
   PUBMED   8093609
REFERENCE   10 (bases 1 to 2858)
  AUTHORS   Shirakata M, Huppi K, Usuda S, Okazaki K, Yoshida K and Sakano H.
  TITLE     HMG1-related DNA-binding protein isolated with V-(D)-J
            recombination signal probes
  JOURNAL   Mol Cell Biol 11 (9), 4528-4536 (1991)
   PUBMED   1678855
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ072796.1, AK146585.1 and AV305902.1.
            
            [WARNING] On May 10, 2023 this sequence was replaced by
            NM_182990.5.
            
            On Feb 7, 2013 this sequence version replaced NM_182990.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147005.1, AK146585.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                CJ072796.1         2-82
            82-2855             AK146585.1         2-2775
            2856-2858           AV305902.1         300-302
FEATURES             Location/Qualifiers
     source          1..2858
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 49.45 cM"
     gene            1..2858
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /note="structure specific recognition protein 1"
                     /db_xref="GeneID:20833"
                     /db_xref="MGI:MGI:107912"
     exon            1..209
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            210..385
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     CDS             332..2458
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /note="recombination signal sequence recognition protein
                     1; facilitates chromatin transcription complex subunit
                     SSRP1"
                     /codon_start=1
                     /product="FACT complex subunit SSRP1"
                     /protein_id="NP_892035.2"
                     /db_xref="CCDS:CCDS38165.1"
                     /db_xref="GeneID:20833"
                     /db_xref="MGI:MGI:107912"
                     /translation="MAETLEFNDIFQEVKGSMNDGRLRLSRQGIIFKNSKTGKVDNIQ
                     AGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDL
                     CVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVSQCTTGKNEVTLEFHQNDDAEVSL
                     MEVRFYVPPTQEDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRI
                     YPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILL
                     FSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQG
                     HSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARGTTTTRSFDFE
                     IETKQGTQYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGINPGYDDYADSDEDQHD
                     AYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASASSSSNEG
                     DSDREEKKREQLKRAKMAKDRKSRRKSSEAKKGKDPNAPKRPMSAYMLWLNASREKIK
                     SDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARREYEKAMKEYEGGRGDSSKR
                     DKSKKKKKVKAKMEKKSTPSRGSSSKSSSRQLSDSFKSKEFVSSDESSSGENKSKKKR
                     RRSEDSEEELASTPPSSEDSASGSDE"
     exon            386..571
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            572..677
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            678..868
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1099
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1100..1203
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1332
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1554
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1555..1627
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1628..1766
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1767..1812
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1942
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            1943..2113
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2202
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            2203..2389
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2858
                     /gene="Ssrp1"
                     /gene_synonym="Hmg1-rs1; Hmgi-rs3; Hmgox; T160"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatgtaccc gttggtcggc ccggatgatg ccgttctagc caagtcttcc tctctatggt
       61 ccgtgcgcga cttccggtgg cgggacgcgg ggctgcgcac gcgggaaaag cttccccggc
      121 atcccttccc ccgcatccct accccctccc ctgcgtcccc ctgcgcccac cgccctcact
      181 gtgccgtcgc gaggctgcag ctcttagaga ttcccaccct gctggacatc tacacaacta
      241 accaggaatt ggggcacagc atccagagaa gggttcgttt tctctggtgc agcctagggc
      301 tgtgtgctca ggccaccacg ggcaggtgaa catggcagag acattggagt tcaacgacat
      361 cttccaggag gtgaaagggt ccatgaatga tgggaggctt cgattgagcc gtcagggtat
      421 catctttaag aacagcaaga cgggcaaagt ggacaacatc caggctgggg agttgacaga
      481 aggcatctgg cgtcgggtag cattaggcca tgggcttaaa ctgctcacaa agaatgggca
      541 tgtctacaag tacgatggct tccgcgaatc ggagtttgag aaactctctg acttcttcaa
      601 aactcactat cgccttgagc taatggagaa ggatctgtgt gtgaagggct ggaactgggg
      661 gacagtgaag tttggaggac agctgctttc ttttgacatt ggtgatcaac cagtctttga
      721 gataccccta agcaatgtgt cccagtgtac cacaggcaag aatgaggtga ccctggaatt
      781 ccaccagaat gacgatgctg aagtatctct catggaggtg cgcttctatg ttcctcccac
      841 gcaggaagat ggtgtggacc ctgtggaggc ctttgcccag aatgttctgt caaaggcaga
      901 tgtgatccag gccaccggag acgccatctg catcttccgg gagctgcagt gtttgactcc
      961 tcgcggtcga tacgatatcc ggatctaccc tacctttcta cacctgcatg gcaagacctt
     1021 tgactacaag atcccctata ctacagttct ccgtctcttc ctgctaccac acaaggatca
     1081 gagacagatg ttctttgtga tcagcttgga tcctcccatc aagcagggcc aaactcgtta
     1141 ccacttcctg atcctcctct tctccaagga tgaggacatc tccttgactc tcaacatgaa
     1201 tgaggaagaa gtagaaaagc gctttgaggg gcgactcacc aagaacatgt caggatccct
     1261 ctatgaaatg gtcagtcggg tcatgaaagc acttgtcaac cgtaaaatca cagtcccagg
     1321 caacttccaa gggcactcag gggcccagtg tattacctgc tcctataagg ccagctcagg
     1381 actcctgtac ccactggagc ggggcttcat ctacgtgcat aagccccctg tgcacatccg
     1441 ctttgatgag atctcttttg tcaactttgc ccgtggcacc acgaccactc gttccttcga
     1501 ctttgagatt gagaccaagc aaggcactca gtataccttc agcagcattg aaagggagga
     1561 gtatggaaag cttttcgatt ttgtcaatgc gaaaaagctc aacatcaaga acagaggact
     1621 gaaagagggc attaacccag gctatgacga ttatgctgac tctgatgaag accagcatga
     1681 tgcctatttg gagaggatga aggaggaggg caagatccgg gaggagaatg ccaatgacag
     1741 cagcgacgac tcaggagaag agactgatga gtccttcaat cctggtgaag aagaagaaga
     1801 tgtggcagag gagtttgaca gcaatgcctc tgccagctcc tccagcaatg agggtgacag
     1861 tgaccgtgaa gagaagaaac gggaacagct caaaagggct aagatggcca aggatcgaaa
     1921 gagccgcagg aagtcttcag aggcaaagaa gggtaaagat ccaaacgccc caaagaggcc
     1981 tatgtctgcg tacatgctgt ggcttaatgc aagccgcgag aagatcaagt cggatcatcc
     2041 tggcatcagt atcacagatc tttccaagaa ggcaggggag atctggaagg gaatgtccaa
     2101 agagaagaag gaggagtggg accgcaaggc tgaggatgct aggagggagt atgagaaagc
     2161 catgaaagag tatgaaggag gaagagggga ctcatctaaa agggacaagt ctaagaagaa
     2221 aaagaaagta aaagcaaaga tggaaaaaaa gtccactcct tcccggggct cgtcatccaa
     2281 gtcttcatcc aggcagttga gtgacagctt caagagcaaa gagtttgtgt ccagtgatga
     2341 gagctcttca ggcgagaaca agagcaaaaa gaagaggagg cggagcgagg actctgaaga
     2401 ggagctagcc agtacccctc caagctcaga ggactctgcc tcgggatctg atgaataaag
     2461 gagggaattc ccacctcgtc acagctccag tctctcacat agtccttgga ttctgtgcca
     2521 tctgagtaac tgctcttggt ggcttccact gccctgaggc tttgagggaa gcacctaacc
     2581 tctgctgctt tgcaaggaag gctccttgca atctggagag agactcggta ggagtgtgtt
     2641 gtcttctact cgcagtgcat tgaaggaccc aagtcctcag cctactttcc tactttctga
     2701 ctgtagtaaa agctgcttcc tgtcctgttc aagttgctgc agcaggggtc atgccaagtc
     2761 aggcctgtag ctcctaatag gggcctattt ctacttttat tttgtatttc tggtctgtga
     2821 aaacaattta ataaagggaa atgactttgg aaacgatg
//
