LOCUS       NM_023464                864 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus SS nuclear autoantigen 1 (Ssna1), mRNA.
ACCESSION   NM_023464
VERSION     NM_023464.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 864)
  AUTHORS   Basnet,N., Nedozralova,H., Crevenna,A.H., Bodakuntla,S.,
            Schlichthaerle,T., Taschner,M., Cardone,G., Janke,C., Jungmann,R.,
            Magiera,M.M., Biertumpfel,C. and Mizuno,N.
  TITLE     Direct induction of microtubule branching by microtubule nucleation
            factor SSNA1
  JOURNAL   Nat Cell Biol 20 (10), 1172-1180 (2018)
   PUBMED   30250060
  REMARK    GeneRIF: Data show that the simple scaffolding mechanism of SS
            nuclear autoantigen 1 (SSNA1) can lead to vast morphological
            changes in neurons.
REFERENCE   2  (bases 1 to 864)
  AUTHORS   Lai,C.K., Gupta,N., Wen,X., Rangell,L., Chih,B., Peterson,A.S.,
            Bazan,J.F., Li,L. and Scales,S.J.
  TITLE     Functional characterization of putative cilia genes by high-content
            analysis
  JOURNAL   Mol Biol Cell 22 (7), 1104-1119 (2011)
   PUBMED   21289087
REFERENCE   3  (bases 1 to 864)
  AUTHORS   Aki,T., Funakoshi,T., Nishida-Kitayama,J. and Mizukami,Y.
  TITLE     TPRA40/GPR175 regulates early mouse embryogenesis through
            functional membrane transport by Sjogren's syndrome-associated
            protein NA14
  JOURNAL   J Cell Physiol 217 (1), 194-206 (2008)
   PUBMED   18459117
  REMARK    GeneRIF: the functional plasma membrane transport of TPRA40 that
            regulates cell division of mouse embryos is mediated by NA14
REFERENCE   4  (bases 1 to 864)
  AUTHORS   Errico,A., Claudiani,P., D'Addio,M. and Rugarli,E.I.
  TITLE     Spastin interacts with the centrosomal protein NA14, and is
            enriched in the spindle pole, the midbody and the distal axon
  JOURNAL   Hum Mol Genet 13 (18), 2121-2132 (2004)
   PUBMED   15269182
REFERENCE   5  (bases 1 to 864)
  AUTHORS   Papin,J. and Subramaniam,S.
  TITLE     Bioinformatics and cellular signaling
  JOURNAL   Curr Opin Biotechnol 15 (1), 78-81 (2004)
   PUBMED   15102471
  REMARK    Review article
REFERENCE   6  (bases 1 to 864)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY703613.1 and AL732309.9.
            
            On Sep 23, 2006 this sequence version replaced NM_023464.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC048360.1, AK003356.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849378, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-638               BY703613.1         2-639
            639-864             AL732309.9         163671-163896       c
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 17.12 cM"
     gene            1..864
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
                     /note="SS nuclear autoantigen 1"
                     /db_xref="GeneID:68475"
                     /db_xref="MGI:MGI:1915725"
     exon            1..121
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..429
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
                     /note="sjoegren syndrome nuclear autoantigen 1 homolog;
                     Sjogren's syndrome nuclear autoantigen 1"
                     /codon_start=1
                     /product="microtubule nucleation factor SSNA1"
                     /protein_id="NP_075953.1"
                     /db_xref="CCDS:CCDS38071.1"
                     /db_xref="GeneID:68475"
                     /db_xref="MGI:MGI:1915725"
                     /translation="MTQQGAALQNYNNELVKCIEELCQKREELCRQIQQEEDEKQRLQ
                     NEVRQLTEKLARVNENLARKIASRNEFDRTIAETEAAYLKILESSQTLLSVLKREAGN
                     LTKATASDQKSSGGKDS"
     exon            122..321
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
                     /inference="alignment:Splign:2.1.0"
     exon            322..864
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      844..849
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
                     /note="hexamer: AATAAA"
     polyA_site      859
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
     polyA_site      864
                     /gene="Ssna1"
                     /gene_synonym="1110003H09Rik; 1190004J23Rik; N14; NA14"
                     /note="major polyA site"
ORIGIN      
        1 gtgggcagtg cgcaggtgcg gacttagctg tgcaggcggc ggttgaggct tccggacgcg
       61 gtgcagacca tgacccaaca gggcgcggcg ctgcagaact acaacaacga gttggtcaag
      121 tgcatcgagg agttgtgtca gaagcgagag gagctgtgcc ggcagatcca gcaagaggag
      181 gacgaaaagc agcggctaca gaatgaggtg aggcagctca cggagaagtt ggcccgcgtc
      241 aacgagaacc tggcgcgcaa gatcgcctct cgcaacgagt ttgaccggac catcgcagaa
      301 accgaggccg cctacctcaa gatcctggag agctctcaga ctctgcttag tgtactcaaa
      361 agagaagctg ggaacctgac taaagccaca gcttcagacc agaagagtag tggaggcaag
      421 gacagctgac gagtgcctgt ttcagccgtg gcctatggct gcttagtcct caacatgtct
      481 gtcctaaagc atctttgttc ttcgtggcct cagatgtctt ttatctctgg tgcccagagg
      541 ggcaatttct gacctccacc tgcctagaca agaaaagccc taggacagtc caatggaaga
      601 ggtgttccca gctccgtact cacatgtgct gtggggaccc tgagcagctc catgaggggc
      661 ctctctctga agctcctgaa tccctttggg ctaccaggaa tgtcctggtc ctggtctgag
      721 tactgtggga gcccctcact ttgtctcccc agccactagg gccccaggcc agacatgttg
      781 aagaaagaat cttgactcca gaaccaaaac cttagggccc atccccatgg cctctggtgt
      841 ttcaataaag gttgttttgc aaga
//
