LOCUS       NM_029373               1154 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus serine-rich single-pass membrane protein 1 (Ssmem1),
            transcript variant 2, mRNA.
ACCESSION   NM_029373
VERSION     NM_029373.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Nozawa K, Zhang Q, Miyata H, Devlin DJ, Yu Z, Oura S, Koyano T,
            Matsuyama M, Ikawa M and Matzuk MM.
  TITLE     Knockout of serine-rich single-pass membrane protein 1 (Ssmem1)
            causes globozoospermia and sterility in male micedagger
  JOURNAL   Biol Reprod 103 (2), 244-253 (2020)
   PUBMED   32301969
  REMARK    GeneRIF: Knockout of serine-rich single-pass membrane protein 1
            (Ssmem1) causes globozoospermia and sterility in male micedagger.
REFERENCE   2  (bases 1 to 1154)
  AUTHORS   Lin Q, Donahue SL, Moore-Jarrett T, Cao S, Osipovich AB and Ruley
            HE.
  TITLE     Mutagenesis of diploid mammalian genes by gene entrapment
  JOURNAL   Nucleic Acids Res 34 (20), e139 (2006)
   PUBMED   17062627
REFERENCE   3  (bases 1 to 1154)
  AUTHORS   Hong S, Choi I, Woo JM, Oh J, Kim T, Choi E, Kim TW, Jung YK, Kim
            DH, Sun CH, Yi GS, Eddy EM and Cho C.
  TITLE     Identification and integrative analysis of 28 novel genes
            specifically expressed and developmentally regulated in murine
            spermatogenic cells
  JOURNAL   J Biol Chem 280 (9), 7685-7693 (2005)
   PUBMED   15613475
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC155848.6, AK006332.1, BU938696.1 and AK006038.1.
            
            On Sep 3, 2010 this sequence version replaced NM_029373.3.
            
            Transcript Variant: This variant (2) uses an alternate exon in the
            5' UTR and 5' coding region, compared to variant 1. It encodes
            isoform b which is longer and has a distinct N-terminus, compared
            to isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU938696.1, AK006332.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                AC155848.6         36987-37004         c
            19-444              AK006332.1         5-430
            445-453             BU938696.1         447-455
            454-864             AK006332.1         440-850
            865-1154            AK006038.1         1052-1341
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 12.52 cM"
     gene            1..1154
                     /gene="Ssmem1"
                     /gene_synonym="1700016K02Rik; 1700025E21Rik"
                     /note="serine-rich single-pass membrane protein 1"
                     /db_xref="GeneID:75647"
                     /db_xref="MGI:MGI:1922897"
     exon            1..257
                     /gene="Ssmem1"
                     /gene_synonym="1700016K02Rik; 1700025E21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..809
                     /gene="Ssmem1"
                     /gene_synonym="1700016K02Rik; 1700025E21Rik"
                     /note="isoform b is encoded by transcript variant 2"
                     /codon_start=1
                     /product="serine-rich single-pass membrane protein 1
                     isoform b"
                     /protein_id="NP_083649.1"
                     /db_xref="CCDS:CCDS19973.1"
                     /db_xref="GeneID:75647"
                     /db_xref="MGI:MGI:1922897"
                     /translation="MGHLLSLFWEVDPPPIPLGFTMPSQDAECRKDDSCGTIGSFLLW
                     YFIIILILMFFSRASVWMSESKQDEDSGTSASLSKASKETSCKRQNREGSWDSSLVMK
                     KPKQNQVSTVTDSEVALVSAYLEQRRVRRHSQFLRVNQIQQDSDTTECDSEESNSGAS
                     SWKESESDHHLSPANIKRRKSVSRQRDMENYEVRQRPCLHCKAMRTREWLTRHFPPSA
                     SVTTPMKGEIQEENLTPGTNTKFSKF"
     exon            258..312
                     /gene="Ssmem1"
                     /gene_synonym="1700016K02Rik; 1700025E21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            313..1154
                     /gene="Ssmem1"
                     /gene_synonym="1700016K02Rik; 1700025E21Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggtcacgga gggaaatcgt tcccggtcac cttcatccct ttgagcatgt ttattttcta
       61 agcaagaagc tatcatggga caccttttgt ctttattttg ggaggtggat ccccctccca
      121 tacctctcgg tttcaccatg cccagtcagg atgccgagtg ccggaaggat gactcttgcg
      181 ggacaatagg aagtttcctg ctttggtact tcatcatcat actgatcctc atgttcttct
      241 ctcgcgcttc cgtctggatg tctgagagca aacaggacga agacagcggg accagtgcgt
      301 cactcagtaa agcaagcaaa gaaacttcct gtaagcgaca aaatagagaa gggtcctggg
      361 actcttcact ggtgatgaag aaaccaaagc agaaccaagt ttccacagta accgattccg
      421 aggtggcttt ggtcagcgcc taccttgaac aaagacgagt caggcgccat tcccagttcc
      481 tccgggtgaa tcagatccag caagatagtg acaccactga atgtgacagc gaggaatcga
      541 actccggagc gtcctcctgg aaggagagtg aaagcgacca tcatctgtca cctgccaata
      601 ttaagaggag gaagtcagtg tccaggcaaa gggatatgga aaactatgaa gtcagacaaa
      661 ggccctgtct ccactgcaaa gccatgagaa ccagggagtg gctgacacgt cacttcccac
      721 caagcgcctc agtaacaacc cccatgaagg gagagattca agaggagaat ttgacacctg
      781 ggaccaacac aaaattcagc aaattttgaa tttggcatcc ttaccttgaa gtcaaaaaga
      841 gaaggcgaat aaaacatgga aaccagagtt gtaggtgagg gagatgttca caataaagcc
      901 tctttactaa caacaacagt ataattggaa cccaagacca atgtcaaatt tcagacaaat
      961 tcattgttta aaacaaggtc agagaatttg ttcatgccac catgggaaca caagacctgt
     1021 atcttctatg tttttttttt ttttaagtca aaagagccca gggcagatag tccatacccc
     1081 aagtatatgt attttgttta tgtctatgaa acaaatatga aagctctttg aaaatatatt
     1141 tatgttgaga aacc
//
