LOCUS       NM_173008               4314 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus scavenger receptor cysteine rich family, 5 domains
            (Ssc5d), mRNA.
ACCESSION   NM_173008 XM_977735 XM_977764
VERSION     NM_173008.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4314)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4314)
  AUTHORS   Liu,H., Xu,J., Lan,Y., Lim,H.W. and Jiang,R.
  TITLE     The Scleraxis Transcription Factor Directly Regulates Multiple
            Distinct Molecular and Cellular Processes During Early Tendon Cell
            Differentiation
  JOURNAL   Front Cell Dev Biol 9, 654397 (2021)
   PUBMED   34150754
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4314)
  AUTHORS   Miro-Julia,C., Escoda-Ferran,C., Carrasco,E., Moeller,J.B.,
            Vadekaer,D.F., Gao,X., Paragas,N., Oliver,J., Holmskov,U.,
            Al-Awqati,Q. and Lozano,F.
  TITLE     Expression of the innate defense receptor S5D-SRCRB in the
            urogenital tract
  JOURNAL   Tissue Antigens 83 (4), 273-285 (2014)
   PUBMED   24641504
  REMARK    GeneRIF: the results indicate that S5D-SRCRB is an integral
            component of the urogenital tract involved in innate immune
            functions.
REFERENCE   4  (bases 1 to 4314)
  AUTHORS   Miro-Julia,C., Rosello,S., Martinez,V.G., Fink,D.R.,
            Escoda-Ferran,C., Padilla,O., Vazquez-Echeverria,C.,
            Espinal-Marin,P., Pujades,C., Garcia-Pardo,A., Vila,J.,
            Serra-Pages,C., Holmskov,U., Yelamos,J. and Lozano,F.
  TITLE     Molecular and functional characterization of mouse S5D-SRCRB: a new
            group B member of the scavenger receptor cysteine-rich superfamily
  JOURNAL   J Immunol 186 (4), 2344-2354 (2011)
   PUBMED   21217009
  REMARK    GeneRIF: Group B scavenger receptor protein S5D-SRCRB might play a
            role in innate defense and homeostasis of certain specialized
            epithelial surfaces.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157563.12, AK079906.1 and BX637081.1.
            
            On Jun 10, 2018 this sequence version replaced NM_173008.2.
            
            Sequence Note: This sequence has been modified as follows: removed
            25 bp suspected to be vector contamination from the 3' end.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU850434.1, BC141044.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                AC157563.12        92723-92745
            24-4283             AK079906.1         2-4261
            4284-4314           BX637081.1         4-34                c
FEATURES             Location/Qualifiers
     source          1..4314
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 2.85 cM"
     gene            1..4314
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /note="scavenger receptor cysteine rich family, 5 domains"
                     /db_xref="GeneID:269855"
                     /db_xref="MGI:MGI:3606211"
     exon            1..159
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     CDS             135..4250
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /note="group B scavenger receptor cysteine-rich
                     domain-containing; scavenger receptor cysteine-rich
                     domain-containing protein LOC284297 homolog; soluble
                     scavenger receptor cysteine-rich domain-containing protein
                     SSC5D; scavenger receptor cysteine rich domain containing
                     (5 domains)"
                     /codon_start=1
                     /product="soluble scavenger receptor cysteine-rich
                     domain-containing protein SSC5D precursor"
                     /protein_id="NP_766596.1"
                     /db_xref="CCDS:CCDS20750.1"
                     /db_xref="GeneID:269855"
                     /db_xref="MGI:MGI:3606211"
                     /translation="MRGLACLLAMLVGIQAIERLRLADGPHGCAGRLEVWHSGRWGTV
                     CDDGWDLRDAEVACRVLGCGGALAAPGGAFFGEGTGPVWLSELNCRGNEGQLGICPHR
                     GWKAHICSHEEDAGVVCVGQRAANSREDSMSLLDGDPWLALSGELSPSSEEPPITHAP
                     QPAASSQNGPRKKNPRPPKQTKSTRAPVLTNGAPHQERLRLVSGPHGCAGRLEVWHGG
                     RWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGEGPVWMDDVGCGGGEEALR
                     DCPRSPWGRSNCDHTEDAGLVCTGPAPRIRLADGPHGCAGRLEVWHGGRWGSVCDDAW
                     DLRDAAVACKELGCGGALAAPGGAFFGEGTGPIILDDLRCRGNETALRFCPARPWGQH
                     DCHHREDAGAVCDGMPLGAVQPTVPAVDSNSTAHRLLSTSVGQMPGPAGPWPPSASPT
                     APPEPGPEAGSPQLRLVAGPSRCSGRLEVWHDGRWGTVCDDSWDMRDSAVVCRELGCG
                     RPRQPDPAAGRFGWGAGPIWLDDVGCMGTEASLSECPAASWGKHNCAHNEDVGVTCTG
                     TPGLDTISDPFSWSWLPGLGRDQDAWLPGELTTKPSASLTSSVPQKPTKVPGKAPKST
                     KKWVTKNARRPTTQPPGMPTTKHSRAPGTPTSLHPTARTSELPKRLTTEAPHRQTSHT
                     TVRLTPRVPWEWTSEPVVSQSTQGPQEVTSEATTTENPQTSLEPSGENTEGSLESSQD
                     PATTPTAGVPVPSGPFRVRLADGPNRCAGRLEVWHAGLWGTVCDDSWDIRDATVACWE
                     LGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEMSLSDCPSGAWGKHNCDHEEDVVLT
                     CTGYTGDDDYPSWTWDPTSGEDLTKGTTVAARPGHTLSWATTTNTEVPSPATQNLPDT
                     DDQGGYESSWTWDTPSGRGLFKGTPTTTKPGSTVTTSTSKSPGHPFPAPRARAGSPRK
                     PTPERRPLPTSATTSSPASSSSPEPSGSRQTSGSWPQLIPDSKQEGTSSSPKPSLLTP
                     GLPSPATFALSTPNTSLLPTRSPELSGSPTPTSPEGLTSASSMLSEVSRLSPTSELTP
                     GPDTTPAPEIIPESSDSSDLPMNTRTPTQPFTASHPTSIPQLNTTSYPTIAPQPTTNP
                     QQPRSPHPATSPQPPTNTHPSSTPATPTESLPSSRKTELSSPTKPRLNSELTFEEAPS
                     TDASQTQNLELFLASESGPSSPSPASNLDPLPTDAFKPPRSQTLHSASDHLTQGPTPN
                     HNPDPFGPCVSPLPPVRVMACEPPALVELVGAVREVGDQLQRLTWVLEQDRQERQVLA
                     LGLAQLVEAAQGLGQLSETVKRLAEVAWPPSTPVPMTTTTEEEERPLRGDV"
     exon            160..186
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            187..495
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            496..609
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            610..723
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            724..1032
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1350
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1512
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1830
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..2394
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            2395..2709
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            2710..2877
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            2878..3036
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     exon            3037..4314
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4287..4292
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /note="hexamer: AACAAA"
     polyA_site      4309
                     /gene="Ssc5d"
                     /gene_synonym="A430110N23Rik; S5D-SRCRB"
                     /note="major polyA site"
ORIGIN      
        1 agagccttca gcccagcctg ctcctagctg tccagggctc ctcagcagct gcttccctcc
       61 ctggctgcct cctcctcccc tctcctgccc tccttcccct ttcaccccat cccctgcccc
      121 tggactctgc gaacatgagg ggcttggcct gcctccttgc aatgctggtg gggatccagg
      181 ctatagagcg actccgcctg gctgatggtc ctcatggctg cgcaggacgc ctggaggtct
      241 ggcacagcgg gcgctggggc accgtgtgtg atgacggatg ggaccttcgg gatgctgaag
      301 tggcctgccg tgtgttaggc tgcggagggg cgctggcagc ccctgggggt gccttcttcg
      361 gggagggcac tgggcctgta tggctcagtg aactgaactg tcggggcaat gagggtcagc
      421 tgggtatctg tccccaccgg ggctggaagg cccatatctg ctctcatgag gaggacgcag
      481 gcgtcgtctg tgtaggtcag cgtgcagcta actctagaga agattcaatg tccctgctgg
      541 atggggatcc atggctggca ctgtctgggg agctaagccc cagctcagag gagcccccta
      601 taactcacgc tccccaacca gcagcaagct cccagaatgg cccccggaag aagaaccccc
      661 ggccacccaa gcagaccaag tccacccgag cccctgtact gacaaatgga gctccccacc
      721 aagagcggct gcgactggtc tcaggtcccc acggatgtgc cggccgcctg gaagtctggc
      781 acggtggacg ttggggcact gtctgtgatg atggatggga cctccgagat gcagcggtgg
      841 cctgcaggga gctgggatgt gggggagcgc tggccgcccc tgggggtgcc agatttggac
      901 ctggtgaggg acctgtgtgg atggatgacg tggggtgtgg aggaggagag gaggccctcc
      961 gagactgtcc ccgaagcccc tggggccgga gcaactgtga ccacaccgag gatgcagggc
     1021 tggtctgcac cggtcctgca cccaggatac gccttgctga tggtccccac ggctgtgctg
     1081 gccgcctgga ggtgtggcat ggtggacgat gggggtcggt gtgtgacgat gcctgggatc
     1141 ttcgcgatgc tgctgtggcc tgcaaggagc tgggctgtgg gggtgccctg gccgccccag
     1201 ggggcgcctt ctttggagag gggactggac ccatcatcct ggatgatctc agatgtcgag
     1261 gaaatgagac agccttgcga ttctgtcctg cgaggccctg gggtcagcac gactgtcacc
     1321 accgggagga tgctggggcc gtgtgtgatg gcatgcctct cggtgctgtg cagcctacag
     1381 ttcctgcagt ggacagcaac agcacagcac acaggcttct gtctacctcc gtgggtcaga
     1441 tgccaggccc agcaggccct tggcctcctt ctgcttctcc tactgcccct ccagagcctg
     1501 ggcccgaagc tgggtccccc cagttgcgcc tggtggctgg acccagcagg tgctctggcc
     1561 ggctggaggt atggcatgac ggacgctggg ggacagtatg tgatgacagc tgggacatga
     1621 gagactcagc tgtggtctgc cgggagctgg gctgtgggag gcctcggcaa ccagaccccg
     1681 cagcaggccg ctttggctgg ggtgcaggcc ccatctggct ggatgacgta ggttgtatgg
     1741 ggacggaggc ttcactgtca gaatgccctg ctgcttcctg ggggaaacac aattgcgccc
     1801 acaatgagga tgtcggggtt acctgcactg ggacccccgg cctggatacc atctcagacc
     1861 ctttcagttg gagctggctc cctgggctgg gtagagatca ggatgcctgg ctcccaggag
     1921 agctaaccac caaaccttct gccagtctca cctccagtgt gccacagaaa cccacaaagg
     1981 ttccagggaa agctcccaag agtaccaaga agtgggtgac taaaaatgca aggagaccaa
     2041 ccactcagcc ccctgggatg ccaaccacca aacattccag ggccccaggc accccaacct
     2101 ccctacatcc aacagcacgt acctctgagt taccaaagag actgaccact gaggctcccc
     2161 acaggcagac ctcacatacc actgtaaggc tgacccctag ggtcccctgg gagtggacct
     2221 cagagcctgt ggtgtcacag tccactcaag gtccccaaga agtgacctct gaggccacca
     2281 caacggaaaa ccctcagacc tctttggagc catcgggtga gaacaccgaa ggctctctgg
     2341 aatcatccca agatccagct accaccccaa ctgctggagt ccctgtgcca tcaggtccct
     2401 tccgggttcg tctggctgat gggcccaaca ggtgtgctgg ccggctagag gtgtggcatg
     2461 ctggactctg gggaacagtc tgtgatgaca gctgggacat ccgggatgcc acagtggcct
     2521 gctgggagct gggttgcgga aaggtccggc cccgagtagg caaaactcac tatggccctg
     2581 gcactgggcc catctggttg gatgacatgg gctgtaaagg aagtgagatg tcactgagtg
     2641 actgcccctc gggggcatgg gggaagcaca actgtgacca cgaagaagac gtggtgctca
     2701 cctgcactgg ctacacgggt gatgacgatt atccttcctg gacctgggac cctacttccg
     2761 gagaggacct gaccaaaggg accacagtgg ctgcgcggcc tggacataca ctttcctggg
     2821 ctaccactac aaacactgaa gtcccctctc cagcaacaca gaaccttcca gacacggatg
     2881 accagggagg ttatgagtct tcctggacgt gggatacacc ttcaggaagg ggtctgttca
     2941 aggggacccc caccacaacc aagcctggat ccacagttac cactagcacc agcaagagtc
     3001 ccggccaccc ctttccagct ccaagggccc gtgcaggttc accaaggaag ccaacacctg
     3061 agcgccggcc gctgcccacc tcagccacca cctcatctcc tgcttcctcc tcttcaccag
     3121 agccttctgg ctcacggcag acctctggct cctggccaca actcatccca gactcaaagc
     3181 aggaggggac ctctagctcc cccaaaccat ctctactcac cccaggactt ccctccccag
     3241 caacctttgc cttgtccact cctaatacca gtttgcttcc aacacgttcc ccagagcttt
     3301 caggcagccc aacacccacc tcccctgaag ggctaacctc tgcctcctct atgctatcag
     3361 aagtgagcag gctttctcct acctcagagc tgactccagg acctgataca acaccagcac
     3421 ctgaaataat cccagaaagt tctgactcct cagacctccc catgaacacc aggaccccca
     3481 cacagccgtt tacagcctct caccccacca gcatccctca actcaacaca acttcttacc
     3541 ccaccattgc ccctcaacct accacaaacc ctcagcaacc caggagccct caccccgcca
     3601 caagtcctca acctcccacc aatactcacc cttcctcaac ccctgccacc cctacagagt
     3661 cccttccatc ctcccgaaag acagaacttt cctctcccac taagcctaga ctaaactcag
     3721 agttgacctt tgaggaagcc ccatccacag acgcatccca gacgcagaac ctagagctct
     3781 ttctagcctc ggagtccggc ccctccagtc cctctccagc ctcaaacttg gacccactac
     3841 ccacagatgc cttcaaacca cccagaagcc agaccttaca ctcagcttca gaccacctca
     3901 ctcaagggcc aacccctaat cacaacccag atccttttgg gccatgtgtg tccccattac
     3961 caccagtaag ggtcatggct tgtgagccac ctgccttggt ggagctggta ggtgctgtga
     4021 gggaggtggg tgaccagctg cagagactga cctgggtcct ggagcaggac cggcaggagc
     4081 gccaagtcct ggcactgggc ctagcccagt tggtagaggc tgctcagggg ttggggcagc
     4141 tgagtgagac tgtaaagagg ctagcagagg tggcctggcc ccccagcact cctgtgccca
     4201 tgaccaccac cacagaggag gaggagaggc ctctgagggg agatgtgtga cccactctga
     4261 aattcacggt gcttaagata ctcttaaaca aaagccaacg tatgtacaat cgaa
//
