LOCUS       NM_001360775            6650 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus single-stranded DNA binding protein 2 (Ssbp2),
            transcript variant 3, mRNA.
ACCESSION   NM_001360775 XM_006517331
VERSION     NM_001360775.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6650)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6650)
  AUTHORS   Steers,N.J., Gupta,Y., D'Agati,V.D., Lim,T.Y., DeMaria,N., Mo,A.,
            Liang,J., Stevens,K.O., Ahram,D.F., Lam,W.Y., Gagea,M.,
            Nagarajan,L., Sanna-Cherchi,S. and Gharavi,A.G.
  TITLE     GWAS in Mice Maps Susceptibility to HIV-Associated Nephropathy to
            the Ssbp2 Locus
  JOURNAL   J Am Soc Nephrol 33 (1), 108-120 (2022)
   PUBMED   34893534
  REMARK    GeneRIF: GWAS in Mice Maps Susceptibility to HIV-Associated
            Nephropathy to the Ssbp2 Locus.
REFERENCE   3  (bases 1 to 6650)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6650)
  AUTHORS   Cajigas,I., Chakraborty,A., Swyter,K.R., Luo,H., Bastidas,M.,
            Nigro,M., Morris,E.R., Chen,S., VanGompel,M.J.W., Leib,D.,
            Kohtz,S.J., Martina,M., Koh,S., Ay,F. and Kohtz,J.D.
  TITLE     The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially
            Organizes Megabase Distant Genes in the Developing Forebrain
  JOURNAL   Mol Cell 71 (6), 956-972 (2018)
   PUBMED   30146317
REFERENCE   5  (bases 1 to 6650)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 6650)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 6650)
  AUTHORS   Batista-Brito,R., Machold,R., Klein,C. and Fishell,G.
  TITLE     Gene expression in cortical interneuron precursors is prescient of
            their mature function
  JOURNAL   Cereb Cortex 18 (10), 2306-2317 (2008)
   PUBMED   18250082
REFERENCE   8  (bases 1 to 6650)
  AUTHORS   van Meyel,D.J., Thomas,J.B. and Agulnick,A.D.
  TITLE     Ssdp proteins bind to LIM-interacting co-factors and regulate the
            activity of LIM-homeodomain protein complexes in vivo
  JOURNAL   Development 130 (9), 1915-1925 (2003)
   PUBMED   12642495
REFERENCE   9  (bases 1 to 6650)
  AUTHORS   Chen,L., Segal,D., Hukriede,N.A., Podtelejnikov,A.V.,
            Bayarsaihan,D., Kennison,J.A., Ogryzko,V.V., Dawid,I.B. and
            Westphal,H.
  TITLE     Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to
            regulate development
  JOURNAL   Proc Natl Acad Sci U S A 99 (22), 14320-14325 (2002)
   PUBMED   12381786
REFERENCE   10 (bases 1 to 6650)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154320.2 and CT009700.8.
            
            On Dec 29, 2021 this sequence version replaced NM_001360775.1.
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.226641.1,
                                           SRR7345562.1655089.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-117               AC154320.2         98327-98443         c
            118-190             AC154320.2         34918-34990         c
            191-252             AC154320.2         20179-20240         c
            253-337             CT009700.8         147672-147756       c
            338-427             CT009700.8         69975-70064         c
            428-487             CT009700.8         48189-48248         c
            488-554             CT009700.8         42624-42690         c
            555-625             CT009700.8         41902-41972         c
            626-717             CT009700.8         37241-37332         c
            718-766             CT009700.8         31728-31776         c
            767-802             CT009700.8         28649-28684         c
            803-857             CT009700.8         27101-27155         c
            858-928             CT009700.8         23500-23570         c
            929-1007            CT009700.8         21428-21506         c
            1008-1036           CT009700.8         19307-19335         c
            1037-1135           CT009700.8         18249-18347         c
            1136-6650           CT009700.8         6186-11700          c
FEATURES             Location/Qualifiers
     source          1..6650
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 47.43 cM"
     gene            1..6650
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="single-stranded DNA binding protein 2"
                     /db_xref="GeneID:66970"
                     /db_xref="MGI:MGI:1914220"
     exon            1..117
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..1165
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="isoform 3 is encoded by transcript variant 3;
                     sequence-specific single-stranded-DNA-binding protein 2"
                     /codon_start=1
                     /product="single-stranded DNA-binding protein 2 isoform 3"
                     /protein_id="NP_001347704.1"
                     /db_xref="GeneID:66970"
                     /db_xref="MGI:MGI:1914220"
                     /translation="MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLS
                     EIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSP
                     VLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGM
                     DPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNALGGPGMPG
                     MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNM
                     YTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMS
                     LSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV"
     exon            118..190
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            191..252
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            253..337
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            338..427
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            428..487
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            488..554
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            555..625
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            626..717
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            718..766
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            767..802
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            803..857
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            858..928
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1007
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1036
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1135
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..6650
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1564..1569
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="hexamer: ATTAAA"
     polyA_site      1591
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="major polyA site"
     regulatory      1688..1693
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="hexamer: AATAAA"
     polyA_site      1715
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="major polyA site"
     regulatory      6567..6572
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="hexamer: CATAAA"
     polyA_site      6594
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
     regulatory      6619..6624
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="hexamer: TATAAA"
     regulatory      6624..6629
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
                     /note="hexamer: AATACA"
     polyA_site      6643
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
     polyA_site      6650
                     /gene="Ssbp2"
                     /gene_synonym="1500004K09Rik; 2310079I02Rik;
                     9330163K02Rik; A830008M03Rik; Hspc116; SSDP2"
ORIGIN      
        1 gaggctgtga tgggttgaca ggtgcgtgac agtgggagct gctctcggca caagcatgta
       61 cggcaaaggc aagagtaaca gcagcgccgt cccgtccgac agccaggccc gggagaagtt
      121 agcactctac gtgtatgaat atctgctcca tgtaggagct cagaaatcgg ctcagacatt
      181 tttatcagag ataagatggg aaaaaaacat cacattgggg gagccgcccg gattcttaca
      241 ttcttggtgg tgtgtatttt gggatctcta ctgtgcagct ccagagagac gggaaacctg
      301 tgaacactcg agcgaagcta aagccttcca tgattatagt gctgcagcag ctcccagccc
      361 cgtgctagga aacatgcccc caggagatgg catgccagta ggtcccgtgc caccagggtt
      421 ctttcagcct tttatgtcgc ctcggtaccc tggcggcccg aggcccccat tgaggatacc
      481 taaccaggca cttggaggtg tcccaggaag tcagccatta ctccccagtg gaatggatcc
      541 aacacgacaa caaggacatc caaatatggg tggaccaatg cagagaatga ctcccccaag
      601 aggaatggtg cccttaggac cacagtctga cccttggtta tcattacaga actatggagg
      661 tgcaatgaga cccccactga atgctttagg tggccctgga atgcctggaa tgaacatggg
      721 tccaggtggt ggtagacctt ggccaaaccc aacaaatgcg aattcaatac cctactcctc
      781 agcgtctcct gggaattacg taggtcctcc gggaggtgga ggaccaccag gaacacccat
      841 catgcctagt ccagcagatt caactaattc tggagacaac atgtatactt taatgaatgc
      901 agtacctcct gggcctaaca gacctaattt tccaatgggc cctggatcag atggtcctat
      961 gggtggatta ggaggaatgg agtcccatca catgaacggc tctttaggct caggagatat
     1021 ggacagtatt tccaagaatt ctcccaataa tatgagcctg agtaaccagc cgggcactcc
     1081 aagggatgac ggtgaaatgg ggggaaattt cttaaatcct tttcagagtg agagttactc
     1141 ccccagcatg accatgagcg tgtgatccgt tgccgcgtct ctcatgaaaa ccatcgtgag
     1201 tcagcccatc acagaactac tacagaagaa aactactcgt cgtgtacagt tagacaaagg
     1261 aatctcagac aaccagacca ccttttagtt cctgctctct cccctatttt gagaagaaag
     1321 cgggtccaaa tgtgattcaa gcaactgtac ggagcggcac attagcattg cccccaactg
     1381 aactgcgatg attatctgtg tgtatgtgtg ggaagagaat gcatcgtata tgcagatctg
     1441 tatgcacata tacgcatacg tgcattgacc cacaggacat tgtaagatag tatcacatga
     1501 catcttaagt agaagtaagt aggactttta tgccatcctt tttttcacgt ttacacttta
     1561 attattaaag gttgctcctg cccttcccca actattttgt gctgtgtaca tcactgcttt
     1621 atataagtta ttttttaagg tgaactcaga tgttatggtt ttgtaaatgt ctgcaatcat
     1681 ggataggaat aaaattgctt atttgagagc tttcattcac tgtgtctgaa gcaagttgcc
     1741 cgtgagcccc aggttgtacc aagtagagac agtgacttca tcctcatgtc caaccaggca
     1801 cccagttacc ttctgtgcaa agtagtgtgg tgctttgtat ataaggaaac ccctcaacag
     1861 tagctcagcc agggcttcat acagtacact tctgcaataa ctgctttaaa ttgagttctt
     1921 tcttgatttg tgtgtcttag atgatgcaga actcattagc taactcaaat gacttaaact
     1981 gtagcaataa agtgacatgg gttatcatac ttttagcaca cattctctct taaacacgat
     2041 aaaatccaaa agtgataaca aaaccacttg tttgaactta cagcgtctcc cagggaacta
     2101 gaagtaaatg tctaataaga cacagcgaga aatggtgttg tatgtttatt cagatttcct
     2161 atgatcattt ctacagacac ttgaaaacag acagacacac tgacatgatt caggttttca
     2221 gcccagagag cagagaatga ggaaactaga ggattctgca gcgtttctgg tttcacccac
     2281 ccagtagctt gcttgctgga gcagaactga tgggtacctg tctgttctgt tgtccctgct
     2341 ctcaggtggc agttccatgc cctgtctgct ctgtcctggg tcagagggct tgcactggga
     2401 ggcagattat ctgtgtagct tatgttcact gcagctggct agatctccat tttgtgtctg
     2461 acagttcaga agggagtaaa gaaacagttt taattatctc ccttatgaaa gcaccctgct
     2521 tgcatgacac ttcccagatc tttgggattc cgtttaatcc tatatccaaa caccaaatcc
     2581 taataggaaa agcatagaga gtttatttta taattgaaaa gacagctctg caacccttgc
     2641 tgttctaact gagatacaaa caaccactga tctctaccct gctagagggt attgcccggg
     2701 cttaggggcg aggattctcc ctttcctgtg ggactgtaac ataactgaaa acgttgacac
     2761 tgtttgcctg ctgttggttc tggacaattg atttctctca gatccacatt gattcatcct
     2821 ttctgaaaat ggaaaatgtt agctgggcat tccagggatg ctgggagcat agaggataaa
     2881 aaagatgaag tagctttaca ctgcagatct agaggacagt atatgagtca tactttataa
     2941 agtacagcgt cagcctacaa ctgtaccaga gagcagcctt gtactagcca gctacaggaa
     3001 cctgtcacag gcagttcaca caggaagtcc atttcccccc agtcactagt ggccacttcc
     3061 ttctctctga ctgtacagag ttgaactgtg ttcagtgggc tcggtctccc agcgcttcct
     3121 ttcctcatct gctctccatc tcgcctggcc ttcgtctctg tcattcatct tctgagaagg
     3181 gaagcaaatg attcctacca ctcgcagaag tcatgagcct aattttactt gggaatctta
     3241 gaatataaat gacacaaatg gcattttaac agtggttgat agagtagcat catgtgtgct
     3301 tctaacctgt tttgtttttt aaaaaagtaa aatggttttg tttttgtttt catttccttt
     3361 ctttcttgga actccgttta aaaaaatacc tgtttccaat gtttaaattc ttgaaaaact
     3421 gaaaaattat ttttaagaca aaactacgtt ctcaaacagg aaaataaaag aatgcttaat
     3481 ttttatagcc agataacttt tgttacccgg agggtaagca ttataactat attgatttta
     3541 tgtagatctt aattatttaa catttattgt ttttctggta agaaatccaa cattgtcatg
     3601 cattctacgg ctgttggccc attcatgtcc tcttgatgta tatgctgctt gccagaggtt
     3661 agctttctgc atacttcagc ccataataat gaaatcagca gtactcacat attttgggca
     3721 tagaatgcac ccataaaatg tgacaatggg cagcaggtgt gagcatgcat ccggtcaccc
     3781 ctccctgccc tccctaacgc accgacgttt gaaagttcgt gtcagtctta agtcctgaat
     3841 ggttcttaac cacctgactt tcttactgtg aagatgccca gtgtaaaaaa aaaaaaaaag
     3901 gctttgataa tttgatggac aaattatcgc tttttaaaaa aaacattcca gtttgggttc
     3961 aattaccagt gaacaggaat tttacagcta aaagtctgag gttaagattt cttgatttct
     4021 gaaagactaa caaatcaatt ccgctccctt caggcaagga aagtgctcag acacacctgt
     4081 cccttcagaa actaaataga gaaaaattct gttccccttc agccaaagaa agtgctcaga
     4141 cacacctgtc cctccagaaa ttaaatagag aaaatctgtt ccatttctct tttcatgatt
     4201 ctgtcaggcg tctgaactcc attgcatttg aaaggaccat tcaggtaaac attcttcagc
     4261 ttggaagtga attcatcttg gcatgtgaag ccccacagcc gcctacatcg ttccccacat
     4321 tgatctgggg ctgtgtcctc agcagggact ctgcacagtt ctcagtactc cataccccgg
     4381 ttagcttgtg gcccggtttc tccatgcctg ccttccatcc caggagatga gatgcaaggg
     4441 ttgagcatct tttccctctc ggctttgcag cgtttgcctc tgcacagtgt gtagtactgg
     4501 tggtagtttt cctgaggaaa gaaatttcag ttttcatccc ttgattatta ctgttcatca
     4561 taagcagtat gagaggtcac agctatgcaa catctgaatg tcctcttgat gctgtttcct
     4621 gttgtgtttt gtgggctgta gctctcctct ccttgagaca ttaactgagg caagaagccc
     4681 atgaatactt ggtatatgga gggaagattg gtgtgatgag accattatca catgttttac
     4741 caaatgccaa ctagtctttt gtagtttttc cttcttaaat ttctctgata tgagaagcaa
     4801 aaccccatgc tagcttaaaa caatgtttct gattttaaac atttgtaaca atctcccctc
     4861 atctgagaaa tatgccttga gaaatacagg aaaagcaaga gtgttaaaac cacctcaatt
     4921 ctgcatacta catgtgtgta tatctgtgtg tatatgttgg gagatgacag cataaatttt
     4981 gcttctaaac cccacttcta ctaagatcat gttattttat atagcactgt tgataaatag
     5041 taaacatttt ttttcttttg acattttatt tcattggtga gatatctgat acaagttatt
     5101 tggaatagca agagaggaga acaccactat tctatatatt gaacaatata taagcaggag
     5161 tagttttccc aggcccagat ttagcttctc agcattggcc ttcatactga gcttgtcaga
     5221 aatcatgcag taattataga ttcctattgt acacatttgt ttataagagg ttggattgat
     5281 atcccctaaa gtgttaactt tacccatgaa cggtaattca gtttggatga cctaatgata
     5341 aacacacatc tgagactttc aatgacttct gtagacttta ttatgaagaa agatatccaa
     5401 ctgactgagt ctcagaggag tttcctctgt ggagtttccc gtggtaactt acagaatttg
     5461 tttcttgagt aaaagaatca attctgtatg gagtttaaat tgaaatgtga atagtttttg
     5521 ctgtatacat ttttaaaatg gaatacagca ctaaaatgaa atatgtaaat gttacagcat
     5581 ttaatgtggg actgagtgtt ttcaatgtat gcatttactg ggtctgatta ggataaacgt
     5641 ttgcttcact ttgactgtcc cagtcactgg aatcttacga tctgcttctc aaacacttag
     5701 tgtttcattt ctaaagcaag atgggctgtt gctttggcaa aggtaagtgt tactattcct
     5761 tgaaaaacaa tataaatact tgttcccagt tattacattt cacttttctt ttgtgacaat
     5821 tggtcccagt gtatcacctg agggtgaggc ttgggtccct tacaggagac tacagtctac
     5881 atagtatgct gtaagctaag ttcctgtgtg tctttgtaac attgttggtt aaatgtaatt
     5941 agccatttat ttgaaaacag cacttcaaat aacctgtcca tcttgcatga tttgagtaaa
     6001 gatctaaatt ttttgcaaaa cttacagaga tttctcttga cataaagtgc tgactgacgt
     6061 ttgtgtgtgg atttagatca aacttcaaaa atatttactt tctttgcatt aagacaatta
     6121 acaatatata aactatatgt taggcaaatg attggaagga catgttattg tttcagatgt
     6181 aaagatggag aaatatttat acatagaatt ctttatccat ggtagccata ttgaattgtt
     6241 tatctaattg tgattttaag gatttaaaat gttttcttac cacatgtgtt aaattgttac
     6301 tatgtcttcc tggaaaatgg agttatttgt aaggttttta taaatgcaca atttatgtat
     6361 aaatataatt gaaacctggg gtgacttggt aattactatc cttaattcag taatggccac
     6421 cagatacctg acacatttgt aaacttggca cctgtgtgtg tatatatgtg tgtgcacatg
     6481 cacattgtta catttattct caagtgaatt tatcacttaa tgtttttgta aaagtacttg
     6541 agctgtttgt gtaatggaaa agtcaccata aagatgtata ttaatgcccc ttaatttggc
     6601 acgtcttcat atttaattta taaaatacat cttttgattt acagtttcta
//
