LOCUS       NM_178750               4395 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus SS18, nBAF chromatin remodeling complex subunit like 1
            (Ss18l1), mRNA.
ACCESSION   NM_178750
VERSION     NM_178750.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4395)
  AUTHORS   Ito,M., Yun,Y., Kulkarni,D.S., Lee,S., Sandhu,S., Nunez,B., Hu,L.,
            Lee,K., Lim,N., Hirota,R.M., Prendergast,R., Huang,C., Huang,I. and
            Hunter,N.
  TITLE     Distinct and interdependent functions of three RING proteins
            regulate recombination during mammalian meiosis
  JOURNAL   Proc Natl Acad Sci U S A 122 (2), e2412961121 (2025)
   PUBMED   39761402
REFERENCE   2  (bases 1 to 4395)
  AUTHORS   Zhang,W., Zhang,R., Wu,L., Zhu,C., Zhang,C., Xu,C., Zhao,S.,
            Liu,X., Guo,T., Lu,Y., Gao,Z., Yu,X., Li,L., Chen,Z.J., Qin,Y. and
            Jiao,X.
  TITLE     NLRP14 deficiency causes female infertility with oocyte maturation
            defects and early embryonic arrest by impairing cytoplasmic UHRF1
            abundance
  JOURNAL   Cell Rep 42 (12), 113531 (2023)
   PUBMED   38060382
REFERENCE   3  (bases 1 to 4395)
  AUTHORS   Fulton,S.L., Wenderski,W., Lepack,A.E., Eagle,A.L., Fanutza,T.,
            Bastle,R.M., Ramakrishnan,A., Hays,E.C., Neal,A., Bendl,J.,
            Farrelly,L.A., Al-Kachak,A., Lyu,Y., Cetin,B., Chan,J.C.,
            Tran,T.N., Neve,R.L., Roper,R.J., Brennand,K.J., Roussos,P.,
            Schimenti,J.C., Friedman,A.K., Shen,L., Blitzer,R.D., Robison,A.J.,
            Crabtree,G.R. and Maze,I.
  TITLE     Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn
            mouse model of Down syndrome
  JOURNAL   Nat Commun 13 (1), 6384 (2022)
   PUBMED   36289231
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4395)
  AUTHORS   Mora-Bermudez,F., Kanis,P., Macak,D., Peters,J., Naumann,R.,
            Xing,L., Sarov,M., Winkler,S., Oegema,C.E., Haffner,C.,
            Wimberger,P., Riesenberg,S., Maricic,T., Huttner,W.B. and Paabo,S.
  TITLE     Longer metaphase and fewer chromosome segregation errors in modern
            human than Neanderthal brain development
  JOURNAL   Sci Adv 8 (30), eabn7702 (2022)
   PUBMED   35905187
REFERENCE   5  (bases 1 to 4395)
  AUTHORS   Rong,Y., Zhu,Y.Z., Yu,J.L., Wu,Y.W., Ji,S.Y., Zhou,Y., Jiang,Y.,
            Jin,J., Fan,H.Y., Shen,L. and Sha,Q.Q.
  TITLE     USP16-mediated histone H2A lysine-119 deubiquitination during
            oocyte maturation is a prerequisite for zygotic genome activation
  JOURNAL   Nucleic Acids Res 50 (10), 5599-5616 (2022)
   PUBMED   35640597
REFERENCE   6  (bases 1 to 4395)
  AUTHORS   de Bruijn,D.R., Peters,W.J., Chuva de Sousa Lopes,S.M., van
            Dijk,A.H., Willemse,M.P., Pfundt,R., de Boer,P. and Geurts van
            Kessel,A.
  TITLE     Targeted disruption of the synovial sarcoma-associated SS18 gene
            causes early embryonic lethality and affects PPARBP expression
  JOURNAL   Hum Mol Genet 15 (19), 2936-2944 (2006)
   PUBMED   16926188
REFERENCE   7  (bases 1 to 4395)
  AUTHORS   Chang,C.C., Ma,Y., Jacobs,S., Tian,X.C., Yang,X. and Rasmussen,T.P.
  TITLE     A maternal store of macroH2A is removed from pronuclei prior to
            onset of somatic macroH2A expression in preimplantation embryos
  JOURNAL   Dev Biol 278 (2), 367-380 (2005)
   PUBMED   15680357
REFERENCE   8  (bases 1 to 4395)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   9  (bases 1 to 4395)
  AUTHORS   Aizawa,H., Hu,S.C., Bobb,K., Balakrishnan,K., Ince,G., Gurevich,I.,
            Cowan,M. and Ghosh,A.
  TITLE     Dendrite development regulated by CREST, a calcium-regulated
            transcriptional activator
  JOURNAL   Science 303 (5655), 197-202 (2004)
   PUBMED   14716005
REFERENCE   10 (bases 1 to 4395)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY274705.1, AK133944.1 and BC054730.1.
            
            On Oct 3, 2009 this sequence version replaced NM_178750.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC054730.1, AK133944.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-231               BY274705.1         1-231
            232-4293            AK133944.1         169-4230
            4294-4395           BC054730.1         4268-4369
FEATURES             Location/Qualifiers
     source          1..4395
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 102.56 cM"
     gene            1..4395
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /note="SS18, nBAF chromatin remodeling complex subunit
                     like 1"
                     /db_xref="GeneID:269397"
                     /db_xref="MGI:MGI:2444061"
     exon            1..386
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     CDS             318..1526
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /note="SS18-like protein 1; synovial sarcoma translocation
                     gene on chromosome 18-like 1"
                     /codon_start=1
                     /product="calcium-responsive transactivator"
                     /protein_id="NP_848865.4"
                     /db_xref="CCDS:CCDS17167.1"
                     /db_xref="GeneID:269397"
                     /db_xref="MGI:MGI:2444061"
                     /translation="MSVAFASARPRGKGEVTQQTIQKMLDENHHLIQCILDYQSKGKT
                     AECTQYQQILHRNLVYLATIADSNQNMQSLLPAPPTQNMNLGPGALSQSGSSQGLHPQ
                     GSLSDTVSTGLPPASLMQGQIGNGPNHVSMQQTAQSTLPTTSMSLSGSGHGTGPGYSH
                     SGPTSQSVPMQGQGAISNYVSRTNINMQSNPVSMMHQQAATSHYNSAQGGSQHYQGQA
                     PIAMMGQGGQGGSMMGQRPMAPYRPSQQGSSQQYLGQEEYYSEQYSHSQGSAEPMSQQ
                     YYPDGHGDYAYQQSSYTEQSYDRSFEDPTQHYYEGGNSQYSQQQAGYQQGTAQQQTYS
                     QQQYPNQQSYPGQQQGYGPAQGAPSQYSSYQQGQGQQYGSYRTSQTGPSAQQQRPYGY
                     EQGQYGNYQQ"
     exon            387..463
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            464..548
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            549..693
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            694..891
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1056
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1158
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1251
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1371
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1499
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     exon            1500..4369
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4346..4351
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /note="hexamer: ATTAAA"
     polyA_site      4369
                     /gene="Ss18l1"
                     /gene_synonym="A230053O16Rik; CREST"
                     /note="major polyA site"
ORIGIN      
        1 ggcacggcgg ggcggggcag ggcgggcgga accaccgaag ctcagcacag ggggcggtgt
       61 accggctacc ggctggacga agagcgcagg ccgggtgcag ggggcctccg cgcggtatcc
      121 tgacctggga ggcagtcgcg taaggcgtgg ggacgcgggg gactcgagcg cgcattggcg
      181 acaggcaggc gggcgagccc acggcaccgc gccccccgtg tccccgcccc cgctctgcgg
      241 agaatgggca cctcgggccg cggggcgcag ccggagaata aaccccaatg atcacgggct
      301 gagtccgcgc caccaccatg tccgtggcct tcgcgtcggc gcggccgaga ggcaaagggg
      361 aggtcactca gcagaccatc cagaagatgc tggatgagaa ccaccacctg atccagtgca
      421 tcctggacta ccagagcaag ggcaagaccg ccgagtgcac gcagtaccag cagatcctgc
      481 accggaacct ggtctaccta gccaccatag cagactccaa tcagaacatg cagtccctgc
      541 ttcccgcgcc tccaacacag aacatgaacc tcgggcccgg agcactgagt cagagtggtt
      601 ccagccaggg cctgcacccc cagggcagcc tcagcgatac cgtcagcaca ggcctgcccc
      661 ccgcctccct catgcagggc cagatcggta acggtccaaa ccacgtgtcc atgcagcaga
      721 cggctcagag cacactgccc acaacctcca tgagcttgtc aggcagtggc catggtactg
      781 gccctgggta cagccactcg gggcctacct cgcagagtgt ccccatgcaa ggccaaggtg
      841 ccatcagcaa ctatgtgtct cggaccaaca tcaacatgca gtctaaccca gtctccatga
      901 tgcaccagca ggcagccacg tcccactaca actcagcaca gggtggaagc cagcattacc
      961 agggccaggc acccattgcc atgatgggcc agggtggcca aggaggcagc atgatggggc
     1021 agcggcccat ggcgccctac agaccctccc agcaaggctc ttcccagcag tacctgggcc
     1081 aagaggagta ctacagcgaa cagtacagcc acagccaggg ctccgcagag cccatgagtc
     1141 aacagtacta cccggatggc cacggtgact acgcctatca gcagtcgtcc tacacagagc
     1201 agagctacga ccgctccttt gaggatccca cacagcacta ctacgagggg ggaaactccc
     1261 agtacagtca gcagcaggct gggtaccagc agggcacagc acagcagcag acctactccc
     1321 agcaacagta tcccaaccag cagagctacc cggggcagca gcagggctac ggtcctgccc
     1381 agggagcccc ctcacagtac tcaagctacc agcaaggaca aggtcagcag tatggaagct
     1441 acagaacatc gcagacggga ccttctgccc agcagcagcg gccttacggc tatgaacagg
     1501 gccagtatgg aaattaccag caataaagaa caagcattgt ctttggaccc ttcatagtag
     1561 tatgttctgg acaagccggt ggcagttctg atgagtagcg acatgttggt caccctctct
     1621 gcccagtgcc gtgtctgcat gagaggcagg ctggtttcat gctgggcgtg atgctgtgtg
     1681 caccactgac tgcgatatgg cgtgacatgt ctggtgctgt gtaaagtatt gtatatcggt
     1741 acgatgggga ggttgtcctg tttgtgtccc ctgcccgctc cctgatgttc ttagctagct
     1801 tggggggggg ttaccgtgtc atcacatgtt ctgtgcctgg tgatgagaca atgtctaaga
     1861 gacatcatgg tccatgctgc tgtgaacaga ctcagtctgc cccctctcat accattgttg
     1921 caaagtggac tgtaaatgtt tcttcaactg gcggctcata gcttgacata catacaccgc
     1981 taggtgacca tttcttctgt gcctaagtag ggcttgagga caccttctgt gtcttgggtc
     2041 atgtcactat aacaaggaag atgtgctttg tgtgcaagga ccatgagctg tcctttccag
     2101 aacttaccaa ttgcctgtgt ctctccagtt tccatgatcc caaaggatgt ctttgtatta
     2161 gcgagtaaag aaggatcgat gactattcca aatgacagtc ggtgagagtg tgggcatcgt
     2221 gaggggagct ttcactaagg agggcgctgt ctgaagagca attcttgctg tctccgagct
     2281 gcttgtgtgt agtatggctt tggcccttgg cgtcatctct aggatttgag tgtgcccaaa
     2341 cctaagttta tagagaattt aaagtactca tgtttaattt tacaagcagt tggcaagtgt
     2401 ttatattact tcttcaggac ctctgagttc agattgccaa gcagatgttc ctttgcgttt
     2461 agggaagtct gaaatccaca ctgcattttt aatgaatcca aataacttta ttacgttctt
     2521 tcaaatgaaa aggacaagtt ttatacagtg agaattgggt gatttttttt ttttttacat
     2581 tcctaggatg tttaatctcg ttttaattct gtgcaaacat gagagacagc ctttttgaaa
     2641 aggttctatc aaaggaaaac accgcatata atgcagcagg catatttttc agcatttatt
     2701 tagataataa caatgttact atgagaagaa aagaacaacc ttgaagatga gtgctcagaa
     2761 caaccaagaa catacaaaac catccccaag gatgcagggc ttggtacatc agacctgtcc
     2821 accaggatgc ttttgcttta tttgtgtctt atatgtagcc cagactggcc tcaaactcac
     2881 tacatagctg aggctgaact taatgatccc ccagcctcca ctcccgggta ctgagaccac
     2941 gggcatgcac caccacatct gttttcagct gatagttttt aaaatataaa acttacctgt
     3001 agctcagtag taaggcacct ttgtggagtt tgcttgaatt aatcttgaca gtcttgctgg
     3061 aacttacagt gcaagctcca tttacttaca ggagaatcaa gggccggatc aaaggacttg
     3121 tctgtgtcgg ctgccgtctt actctaggac attctccctc tccttgggac cattatcaac
     3181 aaccatgggc atatgtgtct cataggcaca gggtttagga aacacacagg caagggctga
     3241 ctacatgacg gctttaactt tacagaaaca agtttctgat cgctacatgg cagaagtatt
     3301 agcaacttga ttttagggac tcatcatctc tttagctcct tccctttctg gcaattttta
     3361 taaaactagc ctacaagctc acttgggggc taaatatccc attgaaaatg tcgaaacatt
     3421 ttaagtaact gtgaaatggt ttttattcct tgccaatctg ggaatatgcc ttttatgtat
     3481 gcatacatgt gcaagtgtgt acgtgtgtgt gtgtgtgtgt gtgtgtatgt atgtgtgtgt
     3541 atgtgtgtat atatatgtgt gtatgttaaa gtgctgtatt agtgtgtatg tgtgtgtgta
     3601 tatgtaaagt gctgtgttag tgtgtgttaa tactttttga aagaaaagaa cacttaaaat
     3661 atgtatcacc ccaaaagttc aatttgaaat gtcttacatt aagaatttct tgaatgttgt
     3721 gtatatattt ttaaaagcac tttgtgaaat agtttgtaca tttatttcct aatttatacc
     3781 tgattttggt gttaatatat ttaatgatta atattgttta tttaatgttt tattgatttt
     3841 tatgtaattt tgtgggggaa agtgatgcca gtctttttca ttgcctgtat tatagctttt
     3901 cttctgtaac atgaatgttt gaaaagtcct aggctgaaat gaacccttcg tgcaggtgtg
     3961 gttgactgtg ttttgttttc aatggttcct cctactgaag gccagaaaag atgcaaaggg
     4021 agatttggaa atcgctgctc attcttcctc ctgtttccca gcatccgttc aatacttggt
     4081 gaacttgacc actgaggact ggggttttca gatgtgctga ccactacgcg ctgcgcttgt
     4141 caggggctat gggtggatgg acatctctgc agacttagca tatagcacag tgggagatgg
     4201 gagatgtccg cagaggcact gggcagacac aggcctggcc cagaaaggag gtgttttcct
     4261 ttcctgttgt acctgttctc agacgtgggc ttcagtgact gagtgtccgt tcaaacttgt
     4321 aaaaagagga agactttcca tttccattaa aacacttttt tagccattaa aaaaaaaaaa
     4381 aaaaaaaaaa aaaaa
//
