LOCUS       NM_001372518            2869 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus serine and arginine-rich splicing factor 12 (Srsf12),
            transcript variant 3, mRNA.
ACCESSION   NM_001372518 XM_006537958
VERSION     NM_001372518.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2869)
  AUTHORS   Thoren,L.A., Norgaard,G.A., Weischenfeldt,J., Waage,J.,
            Jakobsen,J.S., Damgaard,I., Bergstrom,F.C., Blom,A.M., Borup,R.,
            Bisgaard,H.C. and Porse,B.T.
  TITLE     UPF2 is a critical regulator of liver development, function and
            regeneration
  JOURNAL   PLoS One 5 (7), e11650 (2010)
   PUBMED   20657840
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB871710.1, AK046869.1 and BB028293.1.
            
            On Sep 3, 2019 this sequence version replaced XM_006537958.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.2128272.1,
                                           SRR7345562.1988659.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               BB871710.1         10-378
            370-2867            AK046869.1         443-2940
            2868-2869           BB028293.1         246-247
FEATURES             Location/Qualifiers
     source          1..2869
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 14.73 cM"
     gene            1..2869
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /note="serine and arginine-rich splicing factor 12"
                     /db_xref="GeneID:272009"
                     /db_xref="MGI:MGI:2661424"
     exon            1..99
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..820
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /note="isoform 3 is encoded by transcript variant 3;
                     serine-arginine repressor protein; splicing factor,
                     arginine/serine-rich 13B; serine/arginine-rich splicing
                     factor 13B; serine/arginine-rich splicing factor 12"
                     /codon_start=1
                     /product="serine/arginine-rich splicing factor 12 isoform
                     3"
                     /protein_id="NP_001359447.1"
                     /db_xref="CCDS:CCDS89725.1"
                     /db_xref="GeneID:272009"
                     /db_xref="MGI:MGI:2661424"
                     /translation="MSRYTRPPNTSLFVRNVADATRPEDLRREFGRYGPIVDVYIPLD
                     FYSRRPRGFAYVQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERH
                     LCSPSDHRRSRSPSQRRSRSRSSSWGRDRRHSDSLKESRHRRSSYSQSKSRSKSLPRQ
                     STSLRQSRTPRRNSGSRGRSRSKSLPKRSKSMEKSQSRSPQKQTGSGAKSRPHGRHCD
                     SIARSPCKSPRAYTSSGSKTQTTKHSHLRSHSRSRSYHHKNSW"
     exon            100..204
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /inference="alignment:Splign:2.1.0"
     exon            205..308
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /inference="alignment:Splign:2.1.0"
     exon            309..450
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /inference="alignment:Splign:2.1.0"
     exon            451..2869
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2850..2855
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /note="hexamer: AATAAA"
     polyA_site      2869
                     /gene="Srsf12"
                     /gene_synonym="B830039L16; Sfrs13b; Srrp; Srsf13b"
                     /note="major polyA site"
ORIGIN      
        1 gcggcgggct gctgggagcg gggccgcgag aggcatgtct cgctacacca ggccccccaa
       61 cacctccctg ttcgtcagga acgtcgcaga cgccaccagg cccgaggact tgcgccgtga
      121 gtttggccga tatggcccca tagtagacgt ttatatccca ttggacttct acagtcgccg
      181 ccccagagga tttgcttatg ttcagtttga agatgttcgg gatgctgaag acgcacttta
      241 caacctcaac aggaagtggg tatgtggccg gcaaattgaa atacagtttg cacaaggtga
      301 tcgcaaaaca ccaggccaaa tgaagtcaaa agaacgccac ctgtgctccc cgagtgacca
      361 caggagatcc agaagcccca gccagaggag atcgcgcagc cggagttctt catggggaag
      421 agaccggagg cactcggaca gcctgaaaga gtctcggcac aggcggtctt cttacagtca
      481 gtctaaatct cgttccaaat cgctacccag gcagtctacc tccctgaggc agtcacggac
      541 accgagaagg aattctggat ccagaggacg atcaagatcc aagtccttac ccaaaaggtc
      601 caagtcgatg gagaaatcac agtcacgctc gcctcaaaag cagactggct ccggagcaaa
      661 gtccagacca catggacgac actgtgactc catagcaaga tccccatgca agtctcccag
      721 agcgtacacc agttctggat cgaagacaca gacaacaaaa cactcccatc tccggtccca
      781 ctccagatct cggagttacc accataaaaa cagttggtga ggagctcctc ccagcagagc
      841 cgcagagctc tgctccaagc tctcacacct cgctgtggtt aaagtgcttc aaggcccgta
      901 gaaatgcgaa ccgatggtag ccacttcact ttgggcatgt ggaaggaata aaatcgccct
      961 agctttggtt aataaatgtt ttatcacgat ttaagggctc atccacaact cactcactgt
     1021 gtgtgcaatg tcgccattgc atagcctgta cctggttcac cgggcagcga ggggtacttt
     1081 ctgaaagata tcagtaaaat agaaccaatg caaaaattct acttaggtat taaatattgc
     1141 caataatatc ctttaccaaa atatttttta ttctaaagca cttttcacat aaaaaataat
     1201 cgtgactata tgtaattgaa taggccagag acttaaactg ttttgacatc tgtgtctttc
     1261 ttgtgactac ttctgtttaa gctcaggaca gaagtatccc agtctattct agttcaagtt
     1321 acagcattct gaaatctgaa aaggtaaaat ctatatggcg attccatagc cgtttaaaag
     1381 atagctagaa ggtatttaaa agataactca aagaccattt cattgttttt gaacacaaca
     1441 gcacagacca gttgacatga aattgttatc catgtttgct taaactgctt aaagagagcc
     1501 gggtgttggc tcaggcctgt gaccccagcc cttgggaggt ggaagagtta agccagcatg
     1561 gactgggcta cgtgggaccc tgtctaagga aaatcaatga atgctttttt aaaaaaaagt
     1621 gaaaccattt tagaagttct agattttgaa tggcttgaga ctactctaga aattatggtg
     1681 tgggacactc agactccaca aaataaactc atgttaagcc ttacatattt gaagtacagt
     1741 acattttgta taaattcata tttatatcat tatttctata tagctatttt catctgcatt
     1801 tttttctttt tagagctcta gttcaatatc ctaattatat aaaagtcttt taaaaaatta
     1861 aacacagtac attatattaa gaagtactag ctaatgagat ggcctggggg gggaggggtt
     1921 aaacccacac accatccaaa cctggcaacc gagagctagc tgggcaatga gtgcaaaccc
     1981 tggaacccac aagggtgact cctgcagact ctctctgact tccacacttg tagtatggca
     2041 cgtgtgcacc tgaagacaga cagacagaca cacacaggtg cacattaaat gtatgcaaaa
     2101 catttaaggt cgaaactaca ccttcaagcc agataggtag cacatgcctg tcacctcagc
     2161 agcactcagg aagctgaggc aggaatttga gaaaagcttg ggaaattttg agacccatca
     2221 cactcacact caggtgcatg cacgcacgcg cgcgcgcgtg cacacacaca cacacacaca
     2281 caggagagag agacagacag agagacagag acagagaaag agggggtctt cataaacagc
     2341 tttaaggtat ttgactttta ctctacattt tgtaaaccaa ataactttgt tggcaattgt
     2401 tgcttttgta ttgtcgtatc ttagaatttc ttttacaatg tgttttgagg tttacattca
     2461 gacagtttta gtagatctgt gataaaaatg gtttgcaaat ataattgtca aagagatatg
     2521 tttacagatt tactctgtta gatctcatta ctaaaacaca ctgtcagtcc ctacagctaa
     2581 tatttatgcc tggaatacct aagaaacctg tcttacattt tcagtatttg gagccatgtt
     2641 gcttctatca atttcaaata caaagttcca tttttctttg cattttaaaa tcctttatgt
     2701 gagaaacaac tttacaaaat gatttgtaca ttggtgatat ttgaagaagt accacaaatt
     2761 aatgtatatt atactccccg aatatatttt ctctatttaa ccatagcaaa agttatttat
     2821 ttcaaaagtt ccctctggtg ttcctctgta ataaagcaat tgtaacgga
//
