LOCUS       NM_001368687            8831 bp    mRNA    linear   ROD 13-MAY-2024
DEFINITION  Mus musculus serine/arginine repetitive matrix 2 (Srrm2),
            transcript variant 1, mRNA.
ACCESSION   NM_001368687 XM_006525076
VERSION     NM_001368687.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8831)
  AUTHORS   Carvalho,S., Zea-Redondo,L., Tang,T.C.C., Stachel-Braum,P.,
            Miller,D., Caldas,P., Kukalev,A., Diecke,S., Grosswendt,S.,
            Grosso,A.R. and Pombo,A.
  TITLE     SRRM2 splicing factor modulates cell fate in early development
  JOURNAL   Biol Open 13 (4) (2024)
   PUBMED   38656788
  REMARK    GeneRIF: SRRM2 splicing factor modulates cell fate in early
            development.
REFERENCE   2  (bases 1 to 8831)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 8831)
  AUTHORS   Harrow,J.L., Steward,C.A., Frankish,A., Gilbert,J.G.,
            Gonzalez,J.M., Loveland,J.E., Mudge,J., Sheppard,D., Thomas,M.,
            Trevanion,S. and Wilming,L.G.
  TITLE     The Vertebrate Genome Annotation browser 10 years on
  JOURNAL   Nucleic Acids Res 42 (Database issue), D771-D779 (2014)
   PUBMED   24316575
REFERENCE   4  (bases 1 to 8831)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   5  (bases 1 to 8831)
  AUTHORS   Trinidad,J.C., Specht,C.G., Thalhammer,A., Schoepfer,R. and
            Burlingame,A.L.
  TITLE     Comprehensive identification of phosphorylation sites in
            postsynaptic density preparations
  JOURNAL   Mol Cell Proteomics 5 (5), 914-922 (2006)
   PUBMED   16452087
REFERENCE   6  (bases 1 to 8831)
  AUTHORS   Ballif,B.A., Villen,J., Beausoleil,S.A., Schwartz,D. and Gygi,S.P.
  TITLE     Phosphoproteomic analysis of the developing mouse brain
  JOURNAL   Mol Cell Proteomics 3 (11), 1093-1101 (2004)
   PUBMED   15345747
REFERENCE   7  (bases 1 to 8831)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 8831)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 8831)
  AUTHORS   Blencowe,B.J., Issner,R., Nickerson,J.A. and Sharp,P.A.
  TITLE     A coactivator of pre-mRNA splicing
  JOURNAL   Genes Dev 12 (7), 996-1009 (1998)
   PUBMED   9531537
REFERENCE   10 (bases 1 to 8831)
  AUTHORS   Ko,M.S.
  TITLE     An 'equalized cDNA library' by the reassociation of short
            double-stranded cDNAs
  JOURNAL   Nucleic Acids Res 18 (19), 5705-5711 (1990)
   PUBMED   2216762
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122821.4.
            
            On Feb 15, 2019 this sequence version replaced XM_006525076.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AC122821.4         60114-60287         c
            175-445             AC122821.4         56310-56580         c
            446-553             AC122821.4         55339-55446         c
            554-718             AC122821.4         54994-55158         c
            719-796             AC122821.4         53466-53543         c
            797-859             AC122821.4         53037-53099         c
            860-892             AC122821.4         52741-52773         c
            893-943             AC122821.4         52431-52481         c
            944-1036            AC122821.4         51781-51873         c
            1037-1229           AC122821.4         50892-51084         c
            1230-7798           AC122821.4         41822-48390         c
            7799-8086           AC122821.4         40812-41099         c
            8087-8200           AC122821.4         39608-39721         c
            8201-8305           AC122821.4         39392-39496         c
            8306-8831           AC122821.4         38771-39296         c
FEATURES             Location/Qualifiers
     source          1..8831
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.07 cM"
     gene            1..8831
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /note="serine/arginine repetitive matrix 2"
                     /db_xref="GeneID:75956"
                     /db_xref="MGI:MGI:1923206"
     exon            1..174
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            175..445
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..8315
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /note="isoform 1 is encoded by transcript variant 1;
                     serine/arginine repetitive matrix protein 2"
                     /codon_start=1
                     /product="serine/arginine repetitive matrix protein 2
                     isoform 1"
                     /protein_id="NP_001355616.1"
                     /db_xref="CCDS:CCDS89004.1"
                     /db_xref="GeneID:75956"
                     /db_xref="MGI:MGI:1923206"
                     /translation="MYNGIGLPTPRGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRH
                     LEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKD
                     VNPGAKEETPGQRPVVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREA
                     KQIAPEPPKPYSLVRETSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKH
                     RSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR
                     SRSRSAAAKIHTTALTGQSPPLASGHQGEGDAPSVEPGATNIQQPSSPAPSTKQSSSP
                     YEDKDKKEKSAVRPSPSPERSSTGPELPAPTPLLVEQHVDSPRPLAAIPSSQEPVNPS
                     SEASPTRGCSPPKSPEKPPQSTSSESCPPSPQPTKGSRHASSSPESLKPTPAPGSRRE
                     ISSSPTSKNRSHGRAKRDKSHSHTPSHRAGRSRSPATKRGRSRSRTPTKRGHSRSRSP
                     QWRRSRSAQRWGKSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPAT
                     RGRSRSRTPARRGRSRSRTPARRRSRSRTPARRRSRSRTPARRGRSRSRTPARRRSRT
                     RSPVRRRSRSRSQARRSGRSRSRTPARRSGRSRSRTPARRGRSRSRTPARRSARSRSR
                     TPARRGRSRSRTPARRRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR
                     SNSSPEMKKSHVSSRRSRSLSSPRSKAKSLRRSLSGSSPCPKQKSQTPTRRSRSGSSP
                     PKQKSKTPPRQSRSNSPQPKVKSGTPPRPGSVTNMQADECTATPQRQSHSESSPDGEV
                     KSRTPSRQSCSGSSPRVKSSTPPRQSPSRSSSPQPKVKTVISPRGRSHSSSSSPSPSR
                     VTSRTPQRKSRSISPCPKVDSRLRHSRSRSSSPDSKMELGTPLRHSGSTSPYLKSMLQ
                     TPPDQNLSGSKSPCPQKSRDSPTGSSGSFHLCPGVTPSSIVPGESCFSASFVQQKGHT
                     QTWPDTSSPEVMQTQVESPLLQSKSQTSPKGSLSRSSSPVTELTARSPVKQDKSEIST
                     DPKLKSGMSPEQSKTKPDSSIYPLVDSKSFLVQSRLEPSELKERLGLIQEDVASSCIP
                     RDKFSPTQDRPESSTVLKVTPRVLLKERSGAGSPPGKRDQKSLLPNSSQDELMEVEKS
                     EQPLSQVLPSLSPEHKEMPGSNIESSPEVEERPAVLSALDQSQSQPSKAAETPAVASC
                     WSGPQVSPEHKELSHSPPRENSFESSLEFKNSGPVSEVNTGFSPEVKEELNGSFLNQT
                     EADPSVDMKEQSRSSRRSSSELSPEVVEKVGLFSSQKVSSPVLETVQQRTPSRERSSS
                     ASPELKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDTPQTPSRGRSEC
                     DSSPEPKALPQTPRARSHSPSSPERNNKSVTPQRERSGSESSVEQKNLARTSPGQRSR
                     SGSSQELDGKPSASPQERSESDSSPDSKPKTRTPLRQRSHSGSSPEVDSKSRHSPRLS
                     RSGSSPEMKDKPRVLQRAQSGTDSSPEHKIPAPRALPRHSRSGSSSKERGPSPEGSSS
                     SESSPEHAPKSRTARRGSRSSIEPKTKSHTPPRRRSSRSSPELTRKARVSRRSRSASS
                     SPEIRSRTPPRRRRSPSVSSPEPTEKSRSSRRRRSVSSPRTKTTSRRGRSPSPKPRGL
                     QRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPTRQ
                     ESSRTSSRRRRGRSRTPLTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR
                     RSRSRTSPVSRRRSRSVNRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTRRRSRS
                     RTPPVTRRRSRSRTPPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRS
                     RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRAARG
                     KRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALSSSRMSCFSRPSM
                     SPTPLDRCRSPGMLEPLGSARTPMSVLQQTGGSMMDGPGPRIPDHPRSSVPENHAQSR
                     IALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAA
                     AMNLASARTSAIPASVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPAASAVN
                     LAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPTPANLVVGPRSAHGTAPVNIA
                     GSRTPAGLAPTNLSSSRMAPALSGANLTSPRVPLSAYDRVSGRTSPLMLDRARSRTPP
                     SAPSQSRMTSERERAPSPASRMVQASSQSLLPPAQDRPRSPVPSAFSDQSRSVVQTTP
                     VAGSQSLSSGTVAKSTSSASDHNGMLSGPAPGISHAEGGEPPASTGAQQPSTLAALQP
                     AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPAQPEVALKRVPSPTP
                     VPKEAIREGRPQEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
                     SSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRQ
                     PSPQPSPRDLQSSERVSWRGQRGDSHSPGHKRKETPSPRSNRHRSSRSP"
     exon            446..553
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            554..718
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            719..796
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            797..859
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            860..892
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            893..943
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1036
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1229
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..7798
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            7799..8086
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            8087..8200
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            8201..8305
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     exon            8306..8831
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8809..8814
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /note="hexamer: AATAAA"
     polyA_site      8827
                     /gene="Srrm2"
                     /gene_synonym="5033413A03Rik; mKIAA0324; SRm300"
                     /note="major polyA site"
ORIGIN      
        1 gcagtcgaag cccgctgcgg cccctgagga agcgaggagg cggcggcggc ggcggctgag
       61 gcgggcggac cgacgaggcg gcggcttcag gctccgaggg atacgaaaac ttaagcagca
      121 gctgcggcgg gacctccctg tttgacagtc ggcggccgga ggcggcggcg gcgggagcgg
      181 tggtgccccc tgggcacagg gccatgtaca acgggatcgg gctgccgacg ccccggggca
      241 gcggcaccaa cggctacgtt cagcgaaacc tgtccctggt gcggggccgc cgtggtgagc
      301 ggcctgacta caagggagag gaggaactgc ggcacctgga ggctgccctg gtgaagcgac
      361 ctaatcctga catcctggac cacgagcgca agcggcgcgt ggagctgcga tgcctcgagc
      421 tggaggaaat gatggaagag caggggtacg aagaacagca aattcaggaa aaagtggcga
      481 cctttcgact catgttgctg gaaaaggatg tgaaccctgg ggccaaggaa gaaaccccag
      541 ggcagagacc agtggtaact gagacccatc agttggcaga actgaatgag aagaagaatg
      601 aacgactccg tgctgccttt ggcatcagtg actcctatgt ggatggcagt tcttttgatc
      661 ctcagagacg tgctcgagaa gctaaacaaa tagctcctga gcctcccaaa ccatacagcc
      721 ttgttcgaga gaccagcagt tctcgctcac caactccaaa gcaaaagaag aagaaaaaga
      781 agaaagatag aggacgcagg tcagagagca gttctcctcg acgagagagg aagaagagtt
      841 caaagaagaa gaagcacagg tcagaatctg agtccaagaa acggaaacac aggtctccta
      901 ctccaaagag caaacgcaaa tcaaaggaca agaagaggaa acggtctcga agtacaacac
      961 cagctcctaa gagccgtcga gctcatcggt caacttctgc ggactctgct tcttcctctg
     1021 atacttctcg tagtcggtct cgaagtgctg ctgctaaaat tcatacaaca gccttgactg
     1081 ggcaaagtcc tccccttgct tcagggcatc aaggggaggg agatgcacct tctgttgaac
     1141 caggtgccac caacatacaa caacctagta gcccagctcc ctctacaaag caatctagca
     1201 gtccttatga agacaaagat aagaaagaga aatctgcagt tcgacctagc ccctctccgg
     1261 aaaggagcag cacagggcca gaactacctg cccctactcc gctccttgtt gagcaacatg
     1321 tcgactcccc acgacccctt gcagcaatcc cgtccagtca ggagccagtt aacccctcat
     1381 ctgaggcttc cccaacccgg ggctgttcac cacctaagtc tcctgagaaa cctccccagt
     1441 ctacttcctc agaaagttgc ccaccatccc ctcaacctac caaaggttct cggcatgcca
     1501 gctcttctcc tgaaagtctt aaacccacac cagctcctgg gtcccgtcga gagatttctt
     1561 cttcacccac atctaagaat cgctcgcatg gcagagcaaa gcgggataaa tctcattctc
     1621 ataccccatc tcatagagca gggaggtctc gtagtcctgc cactaagagg ggacggtctc
     1681 gatctagaac ccccaccaag agaggtcact ccaggtcccg gtcccctcag tggagaaggt
     1741 caagatctgc acagaggtgg ggaaaatcta gaagtcccca gaggcgtggc cgttcaaggt
     1801 ctcctcagag gccaggttgg tccaggagca gaaataccca gagaagaggc aggtctaggt
     1861 cagcaaggcg aggcagatca cattctagat ctccagctac taggggcaga tcccgatcta
     1921 gaacaccagc tagaaggggt aggtctcggt ccagaacacc tgccaggcga agatcacgat
     1981 ccagaacacc tgccaggcgt aggtctcggt ctagaacacc agctcgcagg ggcaggtcca
     2041 gatcaagaac acccgctcgc cgcaggtcta ggacacgatc accagttcga aggaggtctc
     2101 ggagtagatc ccaagctagg agaagtggta ggtctaggtc cagaacacca gccaggagaa
     2161 gtggcaggtc aagatctaga acaccagcca ggagagggag gtcccggtct agaacgccag
     2221 ccagaagaag cgctcgatct cggtctagaa cgccagccag gagagggagg tcacgatcca
     2281 gaacaccagc acgacgacga tctcgaagta gaagtcttgt gagacgtgga agatctcact
     2341 ctagaacacc acaaagaaga ggacgatctg gctcatcctc agagaggaag aacaaatcta
     2401 gaacatctca gaggagaagc agatccaact caagcccaga aatgaaaaaa tctcacgttt
     2461 cctcaagacg gagcaggtct ctttcttcac cacgatccaa agcaaaatct ttgaggcgaa
     2521 gcctttcagg ttcctctcca tgtcctaaac aaaagtcaca gacaccaacc aggcgaagtc
     2581 gttctggttc ttcaccacct aaacaaaagt caaaaacacc accaagacag agtcgttcaa
     2641 attctcctca gcctaaagta aaatctggaa caccaccaag accagggtct gtaacaaaca
     2701 tgcaggctga tgaatgcact gcaacaccac agagacagag ccattctgaa tcatcacctg
     2761 atggtgaggt gaaatcaagg accccatcaa gacaaagctg ctctgggtct tctcctcgag
     2821 tgaaatctag cacacctcca agacagagcc catctaggtc gtcatctcca caacccaaag
     2881 tgaagacagt gatatcacca agaggaagaa gccattctag ctcctcttct ccaagtccta
     2941 gtagagtgac atctaggaca cctcagagga aaagcagatc aatatctcct tgccccaagg
     3001 tagactctag attaagacat agccgttcta gatcctcctc accagattcc aagatggaac
     3061 tgggaacacc actgagacac tcaggatcta catctccata tctaaaaagc atgctccaga
     3121 ctccaccaga tcaaaatctt tctggatcaa agtcaccctg tccccagaag tctagggatt
     3181 caccaacagg aagctctgga tcttttcacc tctgtccagg tgtaacacct agtagtatag
     3241 taccaggaga gagctgtttt agcgcctcat ttgtgcaaca aaaaggacac actcaaactt
     3301 ggccagatac ttcaagtcca gaagtcatgc agactcaagt ggaatctcca ttgctgcaga
     3361 gcaaatccca aacatctcct aagggtagcc tttccagatc ttcatctcca gtcactgagc
     3421 tgacagccag atcaccagta aaacaagata aaagtgaaat atcaacagat ccaaagctga
     3481 agtcaggaat gtctcctgag cagagtaaga ctaaacctga ctctagcata tatcctttag
     3541 tagactctaa atcttttctg gtgcagagca gattggagcc ttctgaatta aaagagagac
     3601 tgggtttaat tcaagaggat gttgcatcat cttgtatacc aagagacaaa tttagtccta
     3661 cacaggatag gcctgagtct tccacagtac tgaaagtcac acctagagta ctattaaaag
     3721 aaagaagtgg agctggctca cctccaggca aaagagacca aaaaagttta ttacctaatt
     3781 caagtcaaga tgaactaatg gaagtagaaa agtctgagca acctttaagc caagttctac
     3841 ccagtttatc tccagaacat aaagaaatgc ctggaagtaa cattgagtca tctcctgaag
     3901 tagaagaaag gcctgctgta ttgtctgctc ttgaccaaag ccagtcacag ccttcaaaag
     3961 cagcagaaac ccctgcagtg gcttcatgtt ggagtgggcc acaagtttct ccagagcata
     4021 aagaactatc tcattctccc ccaagggaga atagctttga gtcatcttta gagtttaaaa
     4081 actcaggccc tgtttcagaa gtaaatactg gcttttctcc tgaggttaaa gaagaattga
     4141 atggatcatt ccttaatcaa acagaggcag atccatctgt ggacatgaaa gaacagtcaa
     4201 ggtcttccag gcgaagcagt tctgagttat ccccagaagt agtggaaaag gtaggattat
     4261 tttcaagtca gaaagtatct tcgcctgtac ttgagactgt acaacaaaga acaccttcaa
     4321 gagaaagaag tagttctgca tctcctgaac tgaaagatgg tttgcctaga acgccatcta
     4381 ggagaagccg gtctgggtct tctccaggac ttagagatgg gtctgggact ccttctaggc
     4441 atagcctatc tgggtcctct cctgggatga aagatacacc tcaaaccccc tccaggggac
     4501 gaagtgaatg tgactcttct ccagaaccaa aagcattgcc tcagactcct agagcccgaa
     4561 gtcattctcc atcatcccca gagcgcaaca acaagagtgt cacccctcag agagaaagaa
     4621 gtgggtcaga atcatcagta gaacagaaaa atctggctag gacctctccg ggacaaagaa
     4681 gtcgatctgg gtcttcccaa gagcttgatg gaaagcccag cgcgtcccca caggaaagaa
     4741 gtgagtcaga ctcttctcca gattccaaac ccaagactcg gactcctctc agacagagga
     4801 gtcactctgg atcatctcca gaggttgaca gcaaatctcg acactcaccc aggctcagta
     4861 ggtctggctc atctccggaa atgaaagata agccaagagt gctacagagg gctcagagtg
     4921 gtactgattc ttctcctgaa cacaagatac ctgctcctcg ggccctgccc aggcatagta
     4981 gatcaggttc atcaagcaaa gagagaggtc cttcccctga aggaagcagt agttctgagt
     5041 cttctccaga acacgccccc aaatccagaa ctgctcgaag aggttccagg tcctcaatag
     5101 agccaaagac aaagtctcac acaccacctc gacgccggag ctctcgatca tctcctgagc
     5161 taaccaggaa ggctagagtc tctcgtagaa gccggtctgc ctcctcatca ccagaaatcc
     5221 gctccagaac tccaccaaga cgcagaagaa gtccttcagt atcttcacca gagccaactg
     5281 aaaagtcaag gtcttcacgg aggaggcgct cagtttcttc tccccgtacc aagacaactt
     5341 cgaggagagg acggtctcct tcacccaaac ctcgtggact ccaaagatcc cgatcccgct
     5401 cacggagaga gaaaaccaga acaacccgac gcagagatag atctggatca tctcagtcaa
     5461 catctcgaag aagacagagg agccggtcta gatcacgagt tactcggaga cggaggggtg
     5521 gctctggtta ccattcaaga tcacctacca gacaggagag ttctcgaacc tcctctagac
     5581 gcagaagagg ccgctcccgg acacccttga ccagtcggaa gcgatctcga tcaagaacat
     5641 caccagctcc ttggaagcgc tctagatctc gagcctcacc agctactcat cggcggtcca
     5701 ggtccagaac accactgata agccgacgta ggtccagatc tcggacctca cctgtgagta
     5761 ggagacggtc aaggtcagtg aataggcgta gatctcgatc aagagcatcc ccagtgagtc
     5821 gaaggcgatc caggtccaga acaccaccag taactcgtcg tcgttcaaga tccagaacac
     5881 caactcgccg tcgttctcgt tctaggactc ctccagtgac tcgcagaagg tccagatcca
     5941 ggactccacc agtaaccagg aggcgatcta gaagcagaac ttcacctgtt actagaagaa
     6001 gatcaagatc caggacatcc ccagtcaccc ggagaagatc gagatctcga acatctccag
     6061 tcacccggag gcggtcccgt tcccgaacct ctccagtgac aagacgacgc tccaggtctc
     6121 gaactccgcc agcaattcga agacgatcta ggtctcggac accactgttg ccacgcaagc
     6181 gctctcgaag ccgctcacca cttgctatcc gccgccgttc taggtctcgt actcctaggg
     6241 cagctcgagg caagcggtcc ttaacaagat ctcctccagc cattcgtagg cggtctgcat
     6301 ctggaagtag ttctgatcgt tcacgttctg ccactcctcc agcaacaagg aatcattctg
     6361 gatctcggac acctcctgta gcactcagta gctctagaat gagttgcttt agccgtccta
     6421 gcatgtcacc aactcctctt gaccgatgta gatcacctgg aatgcttgaa ccccttggaa
     6481 gcgctagaac gcccatgtct gtgctacagc aaacaggtgg ctccatgatg gatggtccag
     6541 gtcctcggat tcctgatcac ccaagatcat ctgttccaga aaaccatgct cagtctagaa
     6601 ttgcacttgc cttgacagcc atcagtcttg gtactgcccg gccacctcca tccatgtctg
     6661 ctgctggcct tgctgcaaga atgtcccagg ttccagcacc tgtacctctc atgagcctta
     6721 gaacagcccc agctgctaac cttgccagca ggattccagc agcatctgca gcagctatga
     6781 accttgctag tgccaggaca tctgctattc cggcatctgt gaaccttgct gactcaagaa
     6841 caccagctgc tgctgcagct atgaacttag ccagccctag aacagcagtg gctccttcag
     6901 ctgtgaacct tgcagatcct cgaacccctg cagcttcagc tgtgaaccta gcaggagcta
     6961 gaacaccagc tgcattagca gctttgagtc tcacaggctc tgggacacct ccaactgctg
     7021 caaattaccc ctccagttcc agaacacccc aggctccaac ccccgcaaac ctggtggtgg
     7081 gtcctcgatc tgcgcatggc acagctcctg tgaatattgc tggctctaga acccctgcag
     7141 gcttggctcc cacaaatctc tccagttcca ggatggctcc agcattgtct ggtgcaaacc
     7201 tcaccagtcc cagggtgccc ctttctgctt atgatcgtgt tagtggcaga acctcacctt
     7261 taatgcttga tcgagccagg tccagaacac caccatctgc cccaagccag tctagaatga
     7321 cctctgagcg tgagcgggct ccttcccctg cttcaagaat ggttcaggct tcttcgcaat
     7381 ctcttctccc tcctgcacag gatcggcctc ggtcccctgt gccatctgct ttttcagacc
     7441 aatctcgttc agttgtccag accactcctg tagcagggtc tcagtccctt tcatccggga
     7501 cagtagcgaa gtccacatcc tctgctagtg accacaatgg catgctttct ggccctgccc
     7561 ctgggatatc ccatgctgaa ggtggggagc cacctgcctc tactggggcc cagcagcctt
     7621 ctacattggc tgctctgcaa ccagctaagg aacgtcggag ctcttcctcc tcttcatcat
     7681 catctagctc ctcctcctct tcatcatctt catcgtcatc ctcctcttcc tctggctcca
     7741 gttctagtga ttcagagggt tccagccttc cagctcaacc tgaggtggca ctgaaaaggg
     7801 ttcccagccc caccccagtc ccaaaggagg ctattagaga gggacgtcct caggaaccaa
     7861 ccccggccaa aaggaagagg cgctctagca gctccagttc cagctcctcc tcctcctcct
     7921 cttcctcttc ttcctcttcc tcctcctcct catcttcctc ctcctcttct tcctcttctt
     7981 cctcctcttc ttcctcctct tcctcctccc cctcccctgc taagcctggc cctcaggcat
     8041 tacccaaacc tgcaagcccc aagaagccac cccctggcga gaggaggtct cgaagtcctc
     8101 ggaagccaat agactccctt cgggattccc gatccctcag ttactcaccc gttgagcgtc
     8161 gacagccctc gccccaacct tcaccaaggg atctacagag cagtgagcga gtttcctgga
     8221 gaggccagcg aggggacagt cactctcctg gtcacaagag gaaggagaca cctagtcccc
     8281 gttctaatcg tcaccgctcc tccaggtctc cataatctgg attccactac acctcatact
     8341 ctggagacat gagtattcct catttttccc agaagaatca tggaaggagt ctttgtatgc
     8401 cttcccttga accttggcag catcttgagg ggagagcgtc ctctcccacc cacccttttt
     8461 tttttttttt ttttttttgg ttcctgtgaa atgttgatct ctgtgagttt ttcctggttc
     8521 ttgtgttttg ggggttggag tgggagggag ggagtctagg gagggagggg cacagctcag
     8581 gacatctagg cctcagattg tgatgatcca gggagttagc tccctaaatt cttgggtgac
     8641 tgatggttta acttggtaag ttgtaatctt tcctgaaaga ggaaggagct gaagttggtt
     8701 ggccctgctg caccccctta caaggttgtg aggccctctc ccccccaact ttgtttaagg
     8761 cattttggtt ttttaaaatc tgtacagtaa aagcaacttt ttctgtcaaa taaaaatgag
     8821 aaatgcagta a
//
