LOCUS       NM_026130               2934 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus signal recognition particle receptor alpha (Srpra),
            mRNA.
ACCESSION   NM_026130
VERSION     NM_026130.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2934)
  AUTHORS   Lang,S., Benedix,J., Fedeles,S.V., Schorr,S., Schirra,C.,
            Schauble,N., Jalal,C., Greiner,M., Hassdenteufel,S., Tatzelt,J.,
            Kreutzer,B., Edelmann,L., Krause,E., Rettig,J., Somlo,S.,
            Zimmermann,R. and Dudek,J.
  TITLE     Different effects of Sec61alpha, Sec62 and Sec63 depletion on
            transport of polypeptides into the endoplasmic reticulum of
            mammalian cells
  JOURNAL   J Cell Sci 125 (Pt 8), 1958-1969 (2012)
   PUBMED   22375059
REFERENCE   2  (bases 1 to 2934)
  AUTHORS   Farber,C.R., Aten,J.E., Farber,E.A., de Vera,V., Gularte,R.,
            Islas-Trejo,A., Wen,P., Horvath,S., Lucero,M., Lusis,A.J. and
            Medrano,J.F.
  TITLE     Genetic dissection of a major mouse obesity QTL (Carfhg2):
            integration of gene expression and causality modeling
  JOURNAL   Physiol Genomics 37 (3), 294-302 (2009)
   PUBMED   19336533
REFERENCE   3  (bases 1 to 2934)
  AUTHORS   Schlenker,O., Hendricks,A., Sinning,I. and Wild,K.
  TITLE     The structure of the mammalian signal recognition particle (SRP)
            receptor as prototype for the interaction of small GTPases with
            Longin domains
  JOURNAL   J Biol Chem 281 (13), 8898-8906 (2006)
   PUBMED   16439358
REFERENCE   4  (bases 1 to 2934)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK004967.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004967.2, SRR1660811.20421.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2934
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 20.06 cM"
     gene            1..2934
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /note="signal recognition particle receptor alpha"
                     /db_xref="GeneID:67398"
                     /db_xref="MGI:MGI:1914648"
     exon            1..203
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1997
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /note="DP-alpha; SR-alpha; docking protein alpha; signal
                     recognition particle receptor ('docking protein')"
                     /codon_start=1
                     /product="signal recognition particle receptor subunit
                     alpha"
                     /protein_id="NP_080406.1"
                     /db_xref="CCDS:CCDS22959.1"
                     /db_xref="GeneID:67398"
                     /db_xref="MGI:MGI:1914648"
                     /translation="MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGN
                     NSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQS
                     ALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKT
                     KEKAKNNKKRGAKKEGSDGTLATSKTAPAEKSGLSAGPENGELSKEELIRRKREEFIQ
                     KHGKGLDKSSKSTKSDTPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSED
                     INLIRGTGPGGQLQDLDCSSSDDEGATQNTKPSATKGTLGGMFGMLKGLVGSKSLSRE
                     DMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLV
                     QILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTNLAKISFWLLENGFSVLIA
                     ACDTFRAGAVEQLRTHTRRLTALHPPEKHGGRTMVQLFEKGYGKDAAGIAMEAIAFAR
                     NQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNR
                     ALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSL
                     NAKAVVAALMKA"
     exon            204..287
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            288..451
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            452..612
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            613..769
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            770..923
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1012
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1131
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1218
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1391
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1605
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1769
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1868
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
     exon            1869..2934
                     /gene="Srpra"
                     /gene_synonym="1300011P19Rik; D11Mgi27; Srpr"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttggcgca gcaggaagcg gcggcggcgg acgcggcccg agttcccggc cccggtctcg
       61 gcctcaagtc ttctcccgct tccgtcatgc ttgacttctt caccatcttc tcgaagggcg
      121 ggcttgtgct ctggtgtttc cagggcgtga gcgactcgtg caccgggccc gtcaacgcgt
      181 tgattcgttc cgtactgctg caggaacggg gcggtaacaa ctctttcact catgaggctc
      241 tcacactcaa gtataaactg gacaaccagt ttgagctggt gtttgtggtt ggctttcaga
      301 agatcctcac gctgacctat gtagacaagt tgatagatga tgtgcaccga ctgttccggg
      361 ataagtatcg cacagagatc caacaacaga gtgctttaag tctattgaat ggcacatttg
      421 atttccaaaa tgacttcctg cggctccttc gtgaagcaga ggagagcagt aagatccgtg
      481 ctcccactac catgaagaaa tttgaagatt ctgaaaaagc taagaaacct gtgaggtcca
      541 tgattgaaac acggggggaa aagaccaagg aaaaagcaaa aaacaacaaa aaaagggggg
      601 ccaaaaagga aggttctgat ggcactttgg ctactagcaa aacagcccct gcagaaaagt
      661 caggtctctc agcgggacct gagaatggag aactttccaa agaggagctg atccgtagga
      721 agagagagga gttcattcag aagcatggca agggtctgga caaatccagt aaatctacaa
      781 agtcagatac tccaaaggag aagggcaaaa aagcaccccg ggtgtgggaa ctaggtggct
      841 gtgctaacaa ggaagtcttg gattacagta ctcccaccac caatggaact ccagaggcag
      901 ccctttctga agatatcaac ttgattcgag gaactgggcc tgggggacag cttcaagatc
      961 tggattgcag cagctcagat gatgaagggg ccactcaaaa taccaagcct agtgctacca
     1021 agggaactct gggtggcatg tttgggatgc tgaagggtct ggtgggttcc aagagcttga
     1081 gtcgagaaga catggaatct gtgctagaca agatgcgtga tcatctcatt gctaagaatg
     1141 tggctgctga cattgctgtc cagctctgtg aatctgttgc caacaaatta gaagggaaag
     1201 tgatggggac atttagcact gtgacttcaa cagtcaagca agctctccag gaatctctag
     1261 tacagatcct acagccacag cgtcgtgtag acatgctccg ggatatcatg gatgcccaac
     1321 gtcgccagcg cccttatgtt gttaccttct gtggtgttaa tggagtaggg aagtctacca
     1381 atcttgccaa gatttccttt tggcttttag agaatggctt tagtgtcctc attgctgcct
     1441 gtgatacatt tcgggctggg gctgttgagc agcttcgtac acacacccgg cgcctgactg
     1501 ccctccatcc ccccgagaag catggtggcc gtacgatggt gcagttgttt gaaaaaggct
     1561 atggcaagga cgctgctggc attgccatgg aagccattgc ctttgcacgt aaccaaggct
     1621 ttgatgtggt gctggtagac actgctggcc gcatgcaaga caatgcccct ctgatgactg
     1681 ccctggccaa actcattact gtcaatacac ctgacttggt gctgtttgta ggggaggcct
     1741 tagtaggcaa cgaagctgtg gatcaactgg tcaagttcaa cagagccttg gctgaccatt
     1801 ctatggctca gacacctcgg ctcattgatg gcattgttct taccaaattt gacaccattg
     1861 atgacaaggt gggagctgct atctctatga catacatcac aagcaaaccc atcgtctttg
     1921 tgggtactgg ccagacctac tgtgacctac gcagtcttaa tgccaaggct gtggtggctg
     1981 ccctcatgaa ggcttaatgt ggctcttgcc taataccaaa tcgccgcttg ccccaagtcc
     2041 ctattcctat atcaagaatg tgctttagag tatgtgagca acttgtcttc agtgtagtac
     2101 aaaggcagag tgaggggagc tttggagact tgcagctcct tctaacccaa tcctttgttc
     2161 agccctacct ccttctgcaa ggagggccta atcatgttac aatcactgcc caatgaccct
     2221 ccctcttcct actcaggcat ccccttcact ctgcctacag actccatatc atagctttga
     2281 ccaatggttg aaaaacccaa cacctggagt gttgctaact agtgtgatca cagagccatg
     2341 gtgagataag gagcagtttg aggtcccagc tctaatggct taattccaga gccagctctg
     2401 gatcttaatg gcatctatct agaagaatac agcttctggg tccctggtgt caggatgaca
     2461 gccacctcac tgtggcagtg atggtggccc attcttaatt gctgctaatt ataaatctgg
     2521 tgatgaactc tacacccgat tgttgcccca aagcatcagt taggccttgt tacaaatgag
     2581 tgaaaggcga gtgcccactt ctctcagaaa cacggggagc agagttgcct tccaacctgt
     2641 gcctgctccc aaaatctaga tggaagcttt gcatgtttcc ttcctgggag aaagggattg
     2701 ttgagaagga ttcctgttgt cccgtaccca ccccaccctc agcctcctgg gcaggtcctg
     2761 gcttttcctc attctcttct acagtgcctg gtagacaagt gctacgttga agaacacaaa
     2821 cctcttgtta agacttgtcc tgtagtttgg tattacagat gtgctactag tgcaataagg
     2881 tgaaggctgt ctgcccagag aaatacataa tttatataag aaaataaatt tcat
//
