LOCUS       NM_025691               3605 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus signal recognition particle 72 (Srp72), mRNA.
ACCESSION   NM_025691 XM_001002822 XM_132143 XM_896053 XM_896061 XM_896070
            XM_896078 XM_896090 XM_896109 XM_916867 XM_924530 XM_924532
            XM_924533 XM_924534 XM_924537 XM_924542 XM_924545 XM_973233
            XM_974428
VERSION     NM_025691.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3605)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3605)
  AUTHORS   Utz,P.J., Hottelet,M., Le,T.M., Kim,S.J., Geiger,M.E., van
            Venrooij,W.J. and Anderson,P.
  TITLE     The 72-kDa component of signal recognition particle is cleaved
            during apoptosis
  JOURNAL   J Biol Chem 273 (52), 35362-35370 (1998)
   PUBMED   9857079
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK133784.1, BY393170.1, AK017869.1, BE635216.1 and BY647692.1.
            
            On or before Nov 24, 2006 this sequence version replaced
            XM_916867.2, XM_924530.2, XM_001002822.1, XM_924533.2, XM_924545.2,
            XM_924532.2, XM_924534.2, XM_924537.2, XM_924542.2, XM_132143.7,
            XM_896061.2, XM_974428.1, XM_896070.2, XM_896053.2, XM_896109.2,
            XM_896078.2, XM_896090.2, XM_973233.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164131,
                              SAMN01164132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1682              AK133784.1         2-1683
            1683-1691           BY393170.1         403-411
            1692-3524           AK017869.1         248-2080
            3525-3576           BE635216.1         485-536
            3577-3605           BY647692.1         385-413
FEATURES             Location/Qualifiers
     source          1..3605
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 41.45 cM"
     gene            1..3605
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /note="signal recognition particle 72"
                     /db_xref="GeneID:66661"
                     /db_xref="MGI:MGI:1333795"
     exon            1..132
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     CDS             24..2039
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /note="signal recognition particle 72 kDa"
                     /codon_start=1
                     /product="signal recognition particle subunit SRP72"
                     /protein_id="NP_079967.1"
                     /db_xref="CCDS:CCDS39119.1"
                     /db_xref="GeneID:66661"
                     /db_xref="MGI:MGI:1333795"
                     /translation="MASGGSGGVSVPALWSEVNRYGQNSDFTRALKTVNKILQINKDD
                     VTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIE
                     SATQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSN
                     WEKVVPENLGLQEGTHELCYNAACALIGQGQLTQAMKILQKAEDLCRRSFSEDSDGAE
                     EDPQAELAIIHGQMAYIMQLQGRTEEALQLYNQIIKLKPTDVALLAVIANNIITINKD
                     QNVFDSKKKVKLTNAEGVEFKLSKRQLQAIEFNKALLAMYTNQAEQCRKIAASLQSQS
                     PEYLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKA
                     CLILRSIEELRHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQSHQPKSPAHLSLI
                     REAANFKLKYGRKKEAVSDLEQLWKQNSKDIHTLAQLISAYSLVDPEKAKALSKHLPS
                     SDSMSLKVDVEALENSPGATYIRKKGGKVTGDNQPKEQGQGDLKKKKKKKKGKLPKNY
                     DPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKAVSSPPT
                     SPRPGSAATISSSASNIVPPRHQKPAGAPATKKKQQQKKKKGGKSGW"
     exon            133..253
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            254..377
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            378..521
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            522..633
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            634..665
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            666..790
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            791..848
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            849..980
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1109
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1182
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1247
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1248..1343
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1344..1447
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1525
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1663
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1664..1701
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1861
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..3605
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3060..3065
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /note="hexamer: AATAAA"
     polyA_site      3085
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /note="major polyA site"
     regulatory      3579..3584
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /note="hexamer: AATAAA"
     polyA_site      3604
                     /gene="Srp72"
                     /gene_synonym="5730576P14Rik; 72kDa"
                     /note="major polyA site"
ORIGIN      
        1 acctcacccc cacctcctcc aagatggcga gcggcggcag tggtggggtg tcagtccctg
       61 cgctgtggag tgaggtgaac cgttatgggc agaacagcga cttcacgcgt gccctcaaga
      121 ctgtcaacaa gatattgcag atcaacaagg atgatgtcac tgccctgcac tgtaaagtag
      181 tttgccttat ccagaatgga agtttcaaag aagccttgaa tgtcatcaat actcacacca
      241 aagtgttagc caataactcc ctgtcctttg agaaggcata ttgcgagtac aggttgaaca
      301 gaattgagaa tgccttgaag acaatagaga gtgccaccca gcagacagac aaactgaagg
      361 agctttatgg acaagtgctg taccgcctgg aacgctacga tgagtgcttg gctgtgtaca
      421 gagatcttgt ccggaactcc caggacgact atgatgagga gaggaaaaca aacctgtcag
      481 cggtcgttgc cgctcagagc aactgggaaa aagtggttcc tgagaacttg ggtctccaag
      541 aaggcacaca cgagctctgt tacaacgctg catgtgcact gatagggcaa ggccagctga
      601 cccaggccat gaaaatcctg caaaaagctg aagatctttg tcgccgttca ttttcagaag
      661 attcagatgg ggctgaggag gacccccagg cggaactggc catcatccat ggtcagatgg
      721 cgtacatcat gcagctgcag ggtcgcacag aggaggcgct gcagctctac aatcagatca
      781 tcaagctgaa gccaacagat gtggcacttc tcgctgtaat cgcaaataac atcattacca
      841 ttaataagga ccaaaatgtc tttgactcca agaaaaaagt gaaattaacc aatgcagaag
      901 gagtggagtt caagctctca aagagacagc tgcaagccat agagtttaac aaagctttgc
      961 ttgccatgta tacaaaccag gcagaacagt gccgaaaaat agctgccagc ttgcagtcgc
     1021 agagtcctga gtatctcctg cctgtgctaa tccaagccgc ccagctctgt cgtgaaaagc
     1081 agcatacaaa agcaatagag ctgcttcagg aattctctga tcaacatcca gaaaatgcag
     1141 ctgaaatcaa gcttaccatg gcacaattga aaatttccca aggtaatatt tccaaagcgt
     1201 gtctaatcct gagaagtata gaggagctga ggcacaagcc aggcatggta tctgcattgg
     1261 tgaccatgta cagccacgag gaagatattg atagtgccat cgaagtcttc acacaggcta
     1321 tccagtggta ccaaagccac cagcccaaat cccctgctca tttgtccttg ataagagaag
     1381 ctgcaaactt caagctcaaa tatggccgga agaaggaggc agtcagtgac ctagaacagc
     1441 tgtggaaaca gaattcaaaa gatattcaca ccctagccca acttatttct gcttactcgc
     1501 ttgtggatcc agagaaagca aaggctctta gcaaacacct gccctcatcg gatagcatgt
     1561 ctctaaaagt agatgttgag gcgcttgaaa attctcctgg tgctacctac attcggaaga
     1621 agggtggaaa agttactgga gataaccaac caaaggaaca aggacaggga gatttgaaaa
     1681 agaagaagaa gaaaaagaaa ggaaaactgc ctaagaatta tgacccaaaa gttaccccag
     1741 atccagaaag atggctacca atgcgagagc gctcttatta ccgaggaaga aagaagggta
     1801 aaaagaagga ccagattgga aaaggaacac agggagcgac tgcaggagcc tcctctgaac
     1861 tggatgccag taaagccgtg agcagcccac ccacctcccc gagacccggc agtgcggcaa
     1921 caatatcgtc ctctgcaagt aacattgtac ccccaagaca ccagaaacct gcaggcgccc
     1981 cagcaaccaa aaagaaacag caacagaaga agaagaaagg agggaaaagt ggctggtgat
     2041 gacagtgtac ttgttgcagg ctgttcttaa tccagtgtca gtgacattag gaacataata
     2101 aaggtaacac agcaggaagc acagagctcc ctcctccatc cccatagtcc tgaaatgatt
     2161 tcttacactt cagatgcgaa gacatcctcc tcagactgcc tcatcgaatt ggcctgctta
     2221 taccaaatag ctttacagag agaggcctga agatggcagc atacgacaca ttatctaagg
     2281 tttcccggga tttaaataga cagggtttct cctgtttcaa ctagtgtgaa gatacatgtt
     2341 cctatcaagt ctcaccttaa attatgtctt acaaggctaa aagtagaatc ttctgagcat
     2401 tccaagtatg tgtttagagc tatcatgtga tgaaaaggga tcttaataac tgagtggcca
     2461 gaaactcacc gtctaaaata atcttagcca taaattgtcc tgtgatactg gaattgggac
     2521 tctctctcgt gtgtgtgtat ttgtgcacat ctgactcctt tgtacctttg ttgtttccat
     2581 tttcagatta tgttaacata ctgatttagt tccactgaag acctcaaaaa atgtatcagt
     2641 gttccaagta gttgactctt gccccagtgt tctgagggca aatgggtttg ggcttctcag
     2701 tcagaacact taatggccac tatcaagaac ataaactttg acctctttat cttaaagagg
     2761 aaacaatatc aggcggtatt gaaagccaca agagcatttg gccccattaa taatcagatg
     2821 gctccccttt ctggttatgg gacatgacct tcattacctt tttcgaagta acgtggtctg
     2881 cattcatttt gtggtgtaaa tgttgctctt gtctttcatt gctagcaggt cactttcaca
     2941 ctcagcagtt gtgagacaca catgggtgcc tccccatgct tagtattcat ttctgtcacc
     3001 cgagagatca tcatatttct cacctagatt tcctgtgacc aggctactct gttcttgtta
     3061 ataaaagcgc tgctgtgttt gagcatttct gttgaaactt ctccagtggg ttcacaaggc
     3121 tttcctgctc tggggagtta gaataggggc tacttttctg ttcagcatag tcagtgtctg
     3181 cagtgtctaa gaggggtcga cattgctctc cagaggacta aatactctgt gacaggaata
     3241 attgattccg ttccatctcc tttgcttaag gacttttttt tatgttgacc aacagaatct
     3301 tcatattcta aactttgaga attttggtct aagacatcat ggtgaaatac acacgtagcc
     3361 ctcttagttg acattgatac agtcattgct aagccacaga aacctcactt caaataagtt
     3421 atttatctaa acttcatctg tattaacatc tagtaactat ttgggggagg tctttaactg
     3481 gctcagtgtg tgtgtgtgtg tacacacgtg cgcatgcaca ttaataaaca atgtggaaaa
     3541 catccattca ctgtgttaca ttttgaaata aattttaaaa taaactagca gtgaatgtga
     3601 ctaac
//
