LOCUS       NM_001100109            3286 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus signal recognition particle 54B (Srp54b), mRNA.
ACCESSION   NM_001100109 XM_001479059 XM_976391
VERSION     NM_001100109.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3286)
  AUTHORS   Halic,M., Becker,T., Pool,M.R., Spahn,C.M., Grassucci,R.A.,
            Frank,J. and Beckmann,R.
  TITLE     Structure of the signal recognition particle interacting with the
            elongation-arrested ribosome
  JOURNAL   Nature 427 (6977), 808-814 (2004)
   PUBMED   14985753
REFERENCE   2  (bases 1 to 3286)
  AUTHORS   Zopf,D., Bernstein,H.D., Johnson,A.E. and Walter,P.
  TITLE     The methionine-rich domain of the 54 kd protein subunit of the
            signal recognition particle contains an RNA binding site and can be
            crosslinked to a signal sequence
  JOURNAL   EMBO J 9 (13), 4511-4517 (1990)
   PUBMED   1702385
REFERENCE   3  (bases 1 to 3286)
  AUTHORS   Bernstein,H.D., Poritz,M.A., Strub,K., Hoben,P.J., Brenner,S. and
            Walter,P.
  TITLE     Model for signal sequence recognition from amino-acid sequence of
            54K subunit of signal recognition particle
  JOURNAL   Nature 340 (6233), 482-486 (1989)
   PUBMED   2502718
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK136033.1.
            
            On or before Jul 26, 2007 this sequence version replaced
            XM_001479059.1, XM_976391.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.54090.1,
                                           SRR1660819.152885.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3286              AK136033.1         2-3287
FEATURES             Location/Qualifiers
     source          1..3286
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 23.87 cM"
     gene            1..3286
                     /gene="Srp54b"
                     /note="signal recognition particle 54B"
                     /db_xref="GeneID:665155"
                     /db_xref="MGI:MGI:3714357"
     exon            1..477
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            478..587
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     CDS             510..2024
                     /gene="Srp54b"
                     /EC_number="3.6.5.4"
                     /note="signal recognition particle 54 kDa protein; SRP54"
                     /codon_start=1
                     /product="signal recognition particle subunit SRP54"
                     /protein_id="NP_001093579.1"
                     /db_xref="CCDS:CCDS49065.1"
                     /db_xref="GeneID:665155"
                     /db_xref="MGI:MGI:3714357"
                     /translation="MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADV
                     NIKLVKQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQN
                     VIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFY
                     GSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVSNAIQPDNIV
                     YVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTG
                     EHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYE
                     QFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDG
                     AKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNV
                     SQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM"
     exon            588..679
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            680..764
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            765..869
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            870..936
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            937..994
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1145
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1294
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1395
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1482
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1556
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1665
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1836
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1837..1932
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     exon            1933..3286
                     /gene="Srp54b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2389..2394
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Srp54b"
                     /note="hexamer: AATAAA"
     polyA_site      2413
                     /gene="Srp54b"
                     /note="major polyA site"
ORIGIN      
        1 gtactctttc acgtagtcgc tttcccctaa gtcctgactt ttcctcgagg tcgcacccga
       61 ggaggtcctg tctcgctgct agcttgccgc ggcagtgacg tacagggaga acactaaggt
      121 caaaggtcag ctccagcaaa gaaacacccc ttctaccctt atcgggggga gccatagaca
      181 cgggccttag tgcctcggaa gcggaagtgt gttttcacga agggctgaac tccgccgagt
      241 gatgacgtct cctcattggg cggaaggttc ggtggcagtc gtcggtgttc cagctggtgg
      301 tagttggctt cactgtgttg ggcgctgggc ccctagtttc tggagctggg aagttgggcg
      361 gcgggctccg tccctgtcct tcagcttcca gcgttcctgg gtttccttcg gcggcgtggg
      421 gcctcgccaa ggactcgccg gccctgtggg gccacggctt tagtggcgcc ttttgcgagt
      481 tcacataaat acatcttaaa accttcaaga tggttctagc agatcttgga agaaaaataa
      541 catcagcatt acgctcattg agcaatgcca ccattatcaa tgaagaggta ttaaatgcta
      601 tgctgaaaga agtatgtaca gcattattgg aagcagatgt taatattaaa ctagtgaagc
      661 aactcagaga aaatgttaag tctgcaattg atcttgaaga gatggcatct ggactgaaca
      721 aaagaaaaat gattcagcat gctgtattta aagaacttgt aaagcttgta gaccctggag
      781 ttaaagcgtg gacaccgact aagggaaagc aaaatgtgat catgtttgtt ggattgcaag
      841 ggagtggtaa aacgacaaca tgttcaaagt tagcatatta ttaccagagg aaaggttgga
      901 agacctgttt gatatgtgca gatacattca gagcaggagc ctttgaccag ctaaaacaga
      961 atgccaccaa agcaagaatt ccgttctatg gcagctatac tgaaatggat cctgtcatca
     1021 ttgcttctga aggagtggag aaattcaaaa atgaaaattt tgaaattatt attgttgata
     1081 caagtggtcg tcacaaacaa gaagactctt tatttgaaga aatgcttcaa gtttctaatg
     1141 ctatacaacc tgataacatt gtttatgtga tggatgcatc catcggacag gcttgtgagg
     1201 cccaggcgaa ggcctttaaa gacaaagtag atgtagcttc agtaatagtg acaaaactcg
     1261 acggtcatgc gaaaggaggc ggtgctctta gtgcagttgc tgccacaaaa agtccaatta
     1321 ttttcattgg tacaggggaa catatagatg attttgaacc tttcaaaaca caacctttca
     1381 tcagcaaact ccttggaatg ggtgatattg aaggactgat tgataaagtc aatgaattga
     1441 agttggatga taatgaggca cttatagaga agttgaagca cggtcagttt acattgcgag
     1501 acatgtatga acagtttcag aatattatga aaatgggccc attcagtcag atattgggga
     1561 tgattcctgg ctttggcaca gattttatga gcaaagggaa tgagcaggag tcaatggcaa
     1621 ggctgaagaa actgatgaca atcatggaca gtatgaacga tcaagaactg gacagtacag
     1681 atggtgccaa ggttttcagt aagcaaccag ggagaatcca aagagttgcc cggggatcag
     1741 gtgtgtcaac aagagatgtt caagaacttc tgacccagta taccaagttt gcacagatgg
     1801 tcaaaaagat gggaggtatc aaaggacttt tcaaaggcgg tgatatgtct aagaatgtga
     1861 gtcagtcaca gatggcaaaa ttaaaccaac aaatggccaa aatgatggac ccacgagttc
     1921 ttcatcacat gggtggcatg gccggccttc agtcaatgat gcggcagttt cagcagggtg
     1981 ctgctggcaa catgaaaggc atgatgggat tcaataacat gtaaagacgc ccccttacta
     2041 ggaactgaca aggtggatga tgtcatctgc tgagacctca cactttctct ccctcttgca
     2101 aacggggaag aaggatattc ttgcctgtct tgccttcgtt cttttgtctc accgttttcc
     2161 ttgtctccct tcccttctga agttcgggaa gagtgcctgg tttttgtgga agtcatcatt
     2221 tctgctttaa atctattagt tttcaacgtc ctaacacttc ttaagttaaa caaatcatga
     2281 tgtaaaattt tggtatttaa aggtttttaa ttgtctcaaa ggccaagcat tacatttata
     2341 aacagttgcg atcagtaaat tacatgatat tgaagaaaag tgctgcaaaa taaacttcaa
     2401 gtgataagtt aaagggttcg ttaactttct ttaaggtttg atgtggcagc gtaccaccca
     2461 gaaaataggc aaaaagccag caggtacatt taaaggaata tatattgaaa aatttaatca
     2521 tgagtattag aaaatgttat tttaggatga aataacttta ttccaagaaa ctttagcttt
     2581 accatttaaa attgaaatca agaatttggt tacagttcgt aatgtatgat gttttgtatc
     2641 aaacttaaat tttttacata ttttggagtc tcgtggtcct tgattgtttt taaagccatt
     2701 tttatgtttc ttacatacta ttgaaaaata atatgttttg ataatagata atacataaat
     2761 ttgctaatgg aaagtaatac taaactatta ggctacagta ttacacatta aaaataaggc
     2821 cgtagcagca ttggttggtt cattgataac tattgctgtg tgtctgtcct ggaatctcag
     2881 atgagtaagc ttcaattcca gtgacggttg gatgtgttag cacttgcacc atagcacatg
     2941 tgtgaaggtc agagagcaac catgttcttt attctttttt tgtttgtttc tttgagacat
     3001 ggtctcacta tagctctggt tatccttgga actcactatg tggaccaggc tggcctcaaa
     3061 ctcacagagc tccgccttcc tctgcctcct gagtgctgag attaaaagca caagtgacat
     3121 gttgggtttc agaggacaac ttgcagaagt cagttctcat ttcaccatgt gggtccaggg
     3181 tttaaactca gctcagtcac acttggcacc aagtgccttt atccatagag ccatgtcatt
     3241 ggccacagtt ccaaagaaag agaggaagga aggaaaggga gggagg
//
