LOCUS       NM_175318               5240 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus SPT2 chromatin protein domain containing 1 (Spty2d1),
            mRNA.
ACCESSION   NM_175318
VERSION     NM_175318.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5240)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5240)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   3  (bases 1 to 5240)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY787796.1, BC079859.1, AK147856.1 and BX527013.1.
            
            On Dec 12, 2008 this sequence version replaced NM_175318.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660819.14002.1, BC079859.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               BY787796.1         2-191
            191-205             BY787796.1         193-207
            206-2854            BC079859.1         1-2649
            2855-2866           AK147856.1         2666-2677
            2867-4924           BC079859.1         2657-4714
            4925-5240           BX527013.1         193-508
FEATURES             Location/Qualifiers
     source          1..5240
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 30.66 cM"
     gene            1..5240
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /note="SPT2 chromatin protein domain containing 1"
                     /db_xref="GeneID:101685"
                     /db_xref="MGI:MGI:2142062"
     exon            1..340
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /inference="alignment:Splign:2.1.0"
     CDS             281..2329
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /note="SPT2, Suppressor of Ty, domain containing 1; SPT2
                     domain-containing protein 1"
                     /codon_start=1
                     /product="protein SPT2 homolog"
                     /protein_id="NP_780527.2"
                     /db_xref="CCDS:CCDS21293.1"
                     /db_xref="GeneID:101685"
                     /db_xref="MGI:MGI:2142062"
                     /translation="MDFREILLIASKGQGVNHVPKRYSLAVGPPKKDPKVKGVQSAAV
                     QAFLRRKEEELRQKALEEKKRKEELVKKRIELKHDKKARAMAKRTKDNFHGYDGIPVE
                     EKTKKKQLVESHLNQGTDQEYDVEEEDFIDYNQAELDQDYEEEQEPPKAESKPKAPLK
                     SAPSPMNFTDLLRLAEKKQFEPVEIKVVKKAEDRPLTAEELREREFLERKHRKKKPEP
                     DAKLPPPVLKKAPSHKDIMGTKPSRGAGDRQLASKGLPFPQAEKKFRPSTASEKQAAL
                     SSPKSLPGERTKVGSGSSTQPSLREGHNRPVFNGAGKPRPSTCSPSVPKTPASGTQKS
                     ASEHKAKKPLPSHPSHSKPGPTVLSHNKSKSPGVRQPGSNSGSAPGQPNPGTARPTLS
                     SGPVPRRQNGSSSSGPEQSAGGIRKLASNSHLSGRTLNGTNGPGRPASSSSGPGRPIS
                     GSAGSGRPVGSSGGPGQPVNNPHDLRRPMNSLSSPGRAVSGPGRSISGSIPAGRTVNS
                     GPGRPVSSLGPGRAVSNPGLPTKPRCTVVSETISSKNIISRSSNGQINGMKPLLSGYR
                     SAQGPQRLPFPTGYKRPREYEEDDDDEYDSEMDDFIEDEGEPQEEISKHIREIFGYDR
                     KKYKDESDYALRYMESSWKEQQKEEAKSLRLGMQEDLEEMRREEEELKRRKAKKLKRH
                     "
     exon            341..455
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /inference="alignment:Splign:2.1.0"
     exon            456..1988
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /inference="alignment:Splign:2.1.0"
     exon            1989..2157
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /inference="alignment:Splign:2.1.0"
     exon            2158..2235
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /inference="alignment:Splign:2.1.0"
     exon            2236..5226
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4907..4912
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /note="hexamer: AATAAA"
     polyA_site      4924
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
     regulatory      5207..5212
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /note="hexamer: ATTAAA"
     polyA_site      5226
                     /gene="Spty2d1"
                     /gene_synonym="5830435K17Rik; P16H6"
                     /note="major polyA site"
ORIGIN      
        1 gttgcgcaaa tacttgcgag cgctgcggag gcgctgagcg tgtgtgtgtg agtgtgtgtg
       61 tgtatgtgtg tatacataca cacacatact tcgtattcgg cggcagcgcg ggggcggtac
      121 acggcattag aaggcgccgg aagtgtcggt gtcgaggggc ggcgagagaa gggccaccaa
      181 ggcaagccag tcagtagcgc ttaggctcag cgagaggcaa gactcgcatc caccgcgtcc
      241 cgagtccccg gcccagccgg gcttttctct tcggccagac atggacttca gggaaatcct
      301 cttgatcgct tccaaaggac aaggtgtcaa ccacgtaccg aaaaggtaca gtttggcggt
      361 ggggcctcca aagaaagacc caaaagtgaa aggtgtccag tcggcagctg tgcaagcttt
      421 ccttaggcgg aaagaagagg agcttagaca aaaagccttg gaagagaaaa aaaggaaaga
      481 ggaactagtg aaaaagcgaa ttgagctcaa acatgacaaa aaagcaagag ccatggccaa
      541 gaggacaaag gacaattttc atggttacga tgggattcct gttgaggaaa agacaaagaa
      601 gaagcagctg gtggagagcc acctgaacca gggaactgac caggagtatg atgtggagga
      661 ggaagacttc atagactaca atcaggctga gctggaccag gactatgagg aggagcaaga
      721 gccacccaag gctgaaagca aaccaaaggc cccccttaaa agtgccccgt cacccatgaa
      781 cttcactgac ttactgaggc tagctgagaa gaagcagttt gaaccagtgg agatcaaggt
      841 agtgaagaaa gcagaagacc ggcccctgac tgcagaggaa ctgagggagc gagagtttct
      901 tgaacgaaag cataggaaaa agaaacctga acccgatgcc aaactacctc cacccgtgtt
      961 gaaaaaggcg ccctctcata aagacatcat gggtacaaag cccagcagag gtgctgggga
     1021 caggcagctt gcttccaaag gattgccctt tcctcaagct gagaagaaat tcagacccag
     1081 cacggccagt gagaaacaag cagctttgtc ttcacccaaa tccctgccag gcgagaggac
     1141 caaggtaggg tctggcagta gcacccagcc ctcacttcgg gagggtcaca acaggcctgt
     1201 cttcaatggg gctggaaagc cccgccccag cacctgttca ccaagtgtcc caaagactcc
     1261 tgctagcggg actcagaaat ctgcttctga gcacaaagcc aaaaaacctc ttccttctca
     1321 tccgagccat tccaagcctg gacccacggt tctctcacac aacaaatcta agagtccagg
     1381 tgtcagacaa ccaggcagca actctggctc tgctcctggg cagcctaacc cagggacagc
     1441 tcgacccaca cttagttctg gccctgtgcc caggcgccag aacggcagct ccagctcagg
     1501 acctgagcag tcagccggtg ggatcagaaa gctggccagc aattcacatc tctccggacg
     1561 aacactcaac ggcacaaatg gtcctggacg acctgcaagc agctcaagtg gccctgggcg
     1621 acccatcagt ggatctgctg gttctgggag acctgtgggc agttctggag gccccgggca
     1681 gcctgtaaac aatccacatg accttcgacg accaatgaac agtcttagct ctcctgggcg
     1741 ggcagtcagt ggccctggga gatccataag tggttccatt ccagctggac gaactgtcaa
     1801 ttcaggccct ggaagaccag tgagcagcct aggccctgga cgagcagtta gtaacccagg
     1861 cctccccaca aagcccagat gtactgttgt ctcagaaaca atttcttcaa agaatattat
     1921 tagtcggtca agtaatggac agataaatgg aatgaaacct ctcctctctg gctacagatc
     1981 tgctcaaggt cctcaaaggc ttcccttccc tactggctac aaaaggcctc gagagtatga
     2041 agaagatgat gatgatgaat atgactcgga aatggatgat ttcatcgaag atgaaggaga
     2101 acctcaggaa gaaatatcca agcacattcg agaaatcttt ggctatgacc gaaaaaaata
     2161 taaagatgaa agtgactatg ccttacgtta catggagagc agttggaagg agcagcagaa
     2221 ggaggaagcc aagagtttaa gacttggtat gcaagaggac ttagaggaaa tgaggcgtga
     2281 agaggaggaa ctgaaacgtc gaaaagccaa gaagctgaag cgacactagc tgctgctact
     2341 gtagattctg gaagggacac tgcaaggatc acctgccttc agactgagca agcctcttcc
     2401 cggattagat tcacacttgg gcccgcaaga ggaaggaata catactgtcg tttgcaggct
     2461 atcatttgag tgtgcagtgt ttttaaatag cccagggtgg aacctataat ggagatgata
     2521 cgatgctggc catgtgctct gtgaagttag ccattcacgg gtgccggcct tgatcctgat
     2581 gagctatgca cgctaatgtg ggaccactca ccaggcagct gatcattgtt cttttgctac
     2641 ttcaaaagga gaaaaagatt gatgtgtgag tagggtacca cccagatcgc agtctgactt
     2701 ccttaggaag ggcctggccc ttctgtgaat gctgccagca ataaagtgac ctgtcctagt
     2761 ctatgtttga attgaaaacc caggaaagag taggctttat agatattata ttagtctcat
     2821 ccttgtgact gacacacaaa atagaatgaa ttatattgta tttagcttat ttgtgggttg
     2881 gatgctaagc attcttcatt gatcttaggt aataaaactt ttaagttaaa atacaaattt
     2941 tgccagaaga agaatgttct tttccagttt tccttccaag ctttctgtta cgttgatttt
     3001 acatgaagta gatgagaggg cccatactat tggtgattga ttgttgtttg tttgtttcat
     3061 tcctttttat agtaaagaaa gatggttatt cagatattag atatttgaaa gggtagttta
     3121 aagattagca agcaacatgt attttggccc cttctgcttt attctccccc attacaatgc
     3181 tatttgggac cctaaggtgc ccctgtacct cttgatgtta atagttaaca tttcattttt
     3241 agcttaaatt ccttagaaaa tgttaataac caaaaagcca aatgtttagt gtatcaggaa
     3301 taccaccttc tctttgtccg cgttgcactt ttatttctaa ctatgcactg tgaagagaat
     3361 gtttcctgtt ggtgtgaaac cttcttacgt tctatcctgc ttaaagccag acctacagac
     3421 agacttaatg ccatttcaac ctggagccca tccaggctga tgtatggtct ggctggaagg
     3481 aagccatgtc tcaaggacag tcagcaacag aaaatgaaat aacatgctag agactggagt
     3541 gtggaggttt gggagcagcc agaatttgga ttgtgggatg atccacaatg tatctggctt
     3601 tcttaaactg ttaagccatg aggggtggga agccagagag gctatcctac aaagaattct
     3661 tacttttcaa caggtccaga ctttatgcat ttgtccatga tgtcttcatt cttaagcttg
     3721 agtattatgg gtaatcatgt tttgccttcc tttgtgggac catttgaccc aatccttaaa
     3781 acaaactcgt tttgaattga gtttcaaact ttgagaaagt gcaaggattt aattttaaag
     3841 ggtatagaac gcttctaact ctccatgtag gtctttatac actggtagca gaaagtctat
     3901 tattaacttc cctttcccta gcccaccgtt aatataaagg gaggaatatt ccactggata
     3961 agtatgtttg gaacattgtt attgctatca cttgtgtgct tccccgcctc tgtgattttc
     4021 atattcatac tctggaatct gtaattgcgg tcaaagttac tggtggctga aagtttactg
     4081 tactcaattt cagggtgcag ctgtttgcac agaaaggcgc cattgtgcta gattaaagtt
     4141 tcagaacttg gtagagtgag gttgtaatct ctcatgtatg aatgcatttc tgtaacaggc
     4201 atgcatcaac ttttacataa gtactcttgt gtgggccatt aaaaagacac aggaaagatt
     4261 gtaagtccaa atcatgtctt ccattttgct cttctgtatt tcctgaccac ttagaaaaag
     4321 ttcacaagcc tttgaagaaa cagcagcagg ctgttattgt tttcaaggtt tacaaattaa
     4381 gtgcttgatt tttaatgtat tctctctatc tactgttttg attttcagat tttgactcaa
     4441 tatttgaaga tgtgcctttt attgggtgat gttaattctc gaatgtagta atgttgtttc
     4501 acaattgtaa tgttacatgt tcacgggtgt gacattctct aacaaattat tcgataagaa
     4561 agtcattttc atggaactca tggctctgat tgcacagtcc cttgctaaag caaagggcac
     4621 tcttttaagg ctacttcaga actggtcttt gtattttctc taagcgatgg atgtagtcat
     4681 gtccatttag aggcagggta ccacatgtca caggcagccc tgagtgtgtg ccatgagaaa
     4741 gttcaaagac tgtgacaaag tctacaggaa ctcaaaattt catttttgta atggtaaccc
     4801 ccaagatttt ctccaagaaa taaattattt tgtattttat aacttaaaag cagctagtag
     4861 tacatttctg agatacagca ggagaccaaa acatttttcg aaagagaata aatatataaa
     4921 gagagactgg ttgttttatt ttcggtgtgc tgattagact atttattttg tgagtgaatg
     4981 tgatgaaata catattcagg tgtttagcgt gattacgagt ggaatataga tttctctggc
     5041 attattaaat ccatgatgtc ttttacataa tggacaaatc aaatatgaaa gaaggacact
     5101 ttgacatagc ttagcttgtt tcctggtgct gttgacctgc agaagagttt acttttgcat
     5161 atacaggtga atgttttgca atttatgtat acaagaaatt gtaggcatta aaatatttta
     5221 ttgataaaaa aaaaaaaaaa
//
