LOCUS       NM_025697               4144 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus SPRY domain containing 7 (Spryd7), transcript variant
            1, mRNA.
ACCESSION   NM_025697
VERSION     NM_025697.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4144)
  AUTHORS   Skarnes,W.C., Rosen,B., West,A.P., Koutsourakis,M., Bushell,W.,
            Iyer,V., Mujica,A.O., Thomas,M., Harrow,J., Cox,T., Jackson,D.,
            Severin,J., Biggs,P., Fu,J., Nefedov,M., de Jong,P.J., Stewart,A.F.
            and Bradley,A.
  TITLE     A conditional knockout resource for the genome-wide study of mouse
            gene function
  JOURNAL   Nature 474 (7351), 337-342 (2011)
   PUBMED   21677750
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK018153.1, CT009550.5 and AK137685.1.
            
            On Jul 16, 2015 this sequence version replaced NM_025697.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK137685.1, AK018153.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 AK018153.1         2-9
            9-9                 CT009550.5         10552-10552
            10-1618             AK018153.1         11-1619
            1619-4144           AK137685.1         1468-3993
FEATURES             Location/Qualifiers
     source          1..4144
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 33.05 cM"
     gene            1..4144
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="SPRY domain containing 7"
                     /db_xref="GeneID:66674"
                     /db_xref="MGI:MGI:1913924"
     exon            1..366
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..851
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="isoform 1 is encoded by transcript variant 1;
                     chronic lymphocytic leukemia deletion region gene 6
                     protein homolog; CLL deletion region gene 6 protein
                     homolog; SPRY domain-containing protein 7"
                     /codon_start=1
                     /product="SPRY domain-containing protein 7 isoform 1"
                     /protein_id="NP_079973.1"
                     /db_xref="CCDS:CCDS27185.1"
                     /db_xref="GeneID:66674"
                     /db_xref="MGI:MGI:1913924"
                     /translation="MAASAWCCLRCCRDGGTGHIPLKEMPAVQLDTQHMGTDVVIVKN
                     GRRICGTGGCLASAPLHQNKSYFEFKIQSTGIWGIGVATQKVNLNQIPLGRDMHSLVM
                     RNDGALYHNNEEKNRLPANSLPQEGDVVGITYDHVELNVYLNGKNMHCPASGIRGTVY
                     PVVYVDDSAILDCQFSEFYHTPPPGFEKILFEQQIF"
     exon            367..483
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /inference="alignment:Splign:2.1.0"
     exon            484..650
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /inference="alignment:Splign:2.1.0"
     exon            651..753
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /inference="alignment:Splign:2.1.0"
     exon            754..4144
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1129..1134
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="hexamer: TATAAA"
     polyA_site      1148
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="major polyA site"
     regulatory      1673..1678
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="hexamer: AATAAA"
     polyA_site      1692
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="major polyA site"
     regulatory      2090..2095
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="hexamer: AATAAA"
     polyA_site      2116
                     /gene="Spryd7"
                     /gene_synonym="6330409N04Rik; Clld6"
                     /note="major polyA site"
ORIGIN      
        1 agtcaagccc gggcccctgc tcggctctct acagcgccct gcccacccgc cacaccctct
       61 ttgacttggg ctggccgctg gccccgccca cctcccgaca ccgccccgcc cctccgggcg
      121 gtcctcgctc cttcgccggg ggacctcgcc tcagtctccg cttcgcctcc cggccctggc
      181 gtcgctgtgc gggctgcgag gctcccgcga cccagaagca ctcgggcgcg ggcggagcgg
      241 tggggctgtg tagctacgcc atggccgcgt cggcgtggtg ctgcctgcgc tgctgcaggg
      301 acggcgggac tggccacatt cctctcaagg agatgccggc cgtacagttg gacacgcagc
      361 acatgggaac agatgttgtc atcgtgaaaa acggaagaag aatctgtggc actggaggtt
      421 gtttagccag tgcaccctta catcagaaca aaagctactt tgagttcaaa atccagtcta
      481 ctggaatctg gggtataggt gttgcaactc agaaagttaa cttgaaccag attcctcttg
      541 gccgagacat gcatagcctg gtgatgagaa atgacggagc cttgtaccac aacaacgaag
      601 agaaaaacag gctgccagca aacagccttc ctcaggaggg agatgtagtg ggtataacat
      661 atgaccatgt agaattaaat gtatatttga atgggaaaaa catgcattgt ccagcatcag
      721 gtatccgagg gacagtgtat ccagttgtat atgttgacga cagtgcaatt ctggattgcc
      781 agttcagtga attttatcat actcctccac ctggttttga aaaaatacta ttcgagcagc
      841 agatcttctg aatgagtttg ttctcaggac ttagacctct gcaccatcac acaagcgctt
      901 accacgtaat aaagctctcc ttgatcgaga gactcgaaca catgctgaac actgagcttc
      961 taattgttgt ccaaggaacc catgtattca ttataccatg ctgaggtttg gtttaaaaga
     1021 tctaggcaac ttatttaatc ttatttaaac aaatatatat agctctgagt ttgattaaca
     1081 gtattatgtg gtaacatgta tataaatatt taaagggaat ttttcttata taaaatattt
     1141 gacagtgatg tgtaattgag tgattatttt tttgtcatcc tgaacttgag tcaccatagt
     1201 ctgtaatcca ataattttgt gtctccctgt cctttttgat aaaatgaaat ggcagaaatt
     1261 tacatacttg gcagcttaat tttgctgatc tatttcctct gttaatggac tacttttctt
     1321 aaaactgaaa ctgcttcttt tgctgtattg ttgtatccct gctttctgtt gcctttttga
     1381 aagacgagga agttatcaga ccatcttgtt gaagaccatc aagatgagca agtagtgatt
     1441 gctcgtagta tactagcaaa ctctgtaaga gttatgatgc tttaaatata aaataagcca
     1501 agtgtgaagg cacacacctt tatttccagc acttgggaga caaagtcagg tagatttctg
     1561 tgagtttgaa gctagcctag tctatatagt gagtattata agtacccaga caaccagggc
     1621 tgtgtaggga gaacctgtca aaaaaatcta attgtttttt gctataagga ataataaaga
     1681 tgtattaagg aatattcagt attatattta aatattcttc ctgttttgtt aattatatgg
     1741 taataatcat ggaaattttg acataagtga gtcttcatgg tcttgagcct ttgatcttct
     1801 tgagtcactt tttattagtt aacaacctga ctaagctaat cacatcttca aacagttata
     1861 ttctttttct cagataagta tagtcaggag tcatcacaac aaattgtatg atgttgtgag
     1921 gcaaggaaaa tatggacgct agaattcaga gaacagttgc ccagtttcct tctgtcctct
     1981 gctgctgagt ttctcagagt ctaccttaca caaagggtaa tcatactgac atgctgagag
     2041 cctgtgacta gttgatggtg tgtgtaaaat gctttaatta tcagcactta ataaaaatag
     2101 ccatgattat tgtgaagcag tgattttcat ggtgtcttag accagcagga tcactgggga
     2161 actctttaga ataggggaca ttcttggacc cagcccagac ttatgcagta gagactcagg
     2221 tcaggggtgt attctggacc ctgtgcatac tagactaagc aggtaaaatg tctcgagatt
     2281 taaggcaggc tggttttaat tccagaagct atggagttct gcacaatgct tatgtgttat
     2341 ttagtagact acatttggtt atgtgcttcg caaacatatt tacataaacc cacattttac
     2401 ctctgaagat atatagaatt cagactatat atgttattta ttgactttca tctgactttc
     2461 tattttagta attttgattc acaacatgtt taactgggtg tggtggcaca agacagtaac
     2521 ctagcacttg agagatcagg gaaggaggct cacaaattta aggccagact agactatgta
     2581 ctgtaatgtt ccttgtctca aaatacagag gaggctagct ggatagatct atgtggaaaa
     2641 gagaattctc taatttcagt atactgcttt tagtgatctt agtacatcca tctgttatgt
     2701 ttttagattt ttttatttat gtctatgtgt atgtgtatat ctgcagcatg taggtaccca
     2761 aagtctaaag agtgcatcag atcaccaagc tggagttaca tgcagttgtg agctgtctag
     2821 tgtgggtcct gacctctgca agagtagcaa gtgcttttaa tggctgagcc atctgaccaa
     2881 tcccaaactc ttgtttatat ttgtaaaagc tattttttaa atcatcacat tcttttcttt
     2941 ttctgatatt gtatttattc attcacagtc ttatacatgt atgcagtata tatttcttac
     3001 catttttctt ttaattttaa tgttataatc acatgttatt tattccctct tccctttcct
     3061 cccatataac cctcctagtt ctctttcgaa ttcatggctt ctttttttat taatagttgt
     3121 tacatgtata catgtatata catgtataca tatacataca tacatgtata tacatgtata
     3181 ttcctaaatg taatctgctc agtctgcata atgttagctc gtctgtgcgt gtgcacaggg
     3241 ctcaccattt tgtaatggtg tcctcttccc tggagaggac tgtttctctc actctgcatt
     3301 ccttagttgt ctgtcattct ttgtgtaggt ttgaggtcac ttggtctttc ccttgtccac
     3361 tttggcctgt tgttgtcctt gttcagctca ggtgtagtca gacatgtttt tttgtttgtt
     3421 tgttttttgt tttttaaagc actttgtatt tatagctttc ttttcttctc ttctcttttc
     3481 tttttaaaga tttattttat ttacatgagt acacggtagc tgtcttcaga cacaccagaa
     3541 gagggcacca gaagagggca tcagatccca ttacagatgg ttgtgagcca ctatatggtt
     3601 gctgggaatt gaactttgga ccttcagaag agcagtctgt gctcttaact gcagagccat
     3661 ctctccagcc ccttagtcat gttaatgaga ctttcagggt atagattctg acattactag
     3721 gagacacagt ctgagagcaa actccctgat cctctggctc ttacagtctt tctactccct
     3781 tttctacagt gttccctgac ccctaggcgt gggagttgtc ttgtagatgt atcccttggg
     3841 actgtgttcc acaactctgc atttcgattg ttacgagttt gtgtcatggt ctctgttgta
     3901 agtggatcgt taaaatggat ctgttgcaaa gaaaagttcc acggagggat gaggactagg
     3961 agccttcagt aaatgagaac atgtgacatt tgtctttctg ggtctgagtt accttactca
     4021 atatgatctt cctatctact taacctgtaa acataatgat tttatttaca tctgaatagt
     4081 attctgtagt attctacatt tttcattata aaagagcaac tagaaataaa gcatcaaaag
     4141 gtcc
//
