LOCUS       NM_001033277            2454 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus SPRY domain containing 3 (Spryd3), mRNA.
ACCESSION   NM_001033277 XM_484507 XM_902706 XM_902709 XM_916955 XM_924587
            XM_924590
VERSION     NM_001033277.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2454)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2454)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2454)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY739425.1, BU057890.1, CX201967.1, BG293312.1, AI427285.1,
            CA323202.1 and BQ031507.1.
            
            On Nov 17, 2007 this sequence version replaced NM_001033277.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN01164135
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-65                BY739425.1         1-65
            66-829              BU057890.1         1-764
            830-1191            CX201967.1         329-690
            1192-1561           BG293312.1         277-646
            1562-1936           AI427285.1         144-518
            1937-2293           CA323202.1         128-484
            2294-2454           BQ031507.1         1-161               c
FEATURES             Location/Qualifiers
     source          1..2454
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 57.3 cM"
     gene            1..2454
                     /gene="Spryd3"
                     /note="SPRY domain containing 3"
                     /db_xref="GeneID:223918"
                     /db_xref="MGI:MGI:2446175"
     exon            1..80
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..1386
                     /gene="Spryd3"
                     /EC_number="2.7.1.112"
                     /codon_start=1
                     /product="SPRY domain-containing protein 3"
                     /protein_id="NP_001028449.2"
                     /db_xref="CCDS:CCDS49738.1"
                     /db_xref="GeneID:223918"
                     /db_xref="MGI:MGI:2446175"
                     /translation="MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQE
                     RFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQY
                     YSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQ
                     IFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYED
                     EWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIAL
                     GLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRD
                     YILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEDGEEIEQEH
                     EGKKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG"
     exon            81..227
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            228..303
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            304..428
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            429..564
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            565..750
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            751..900
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            901..958
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1078
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1251
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..2437
                     /gene="Spryd3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2407..2412
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spryd3"
                     /note="hexamer: AATAAA"
     polyA_site      2437
                     /gene="Spryd3"
                     /note="major polyA site"
ORIGIN      
        1 ggatgtgtgt ggtggcggcg gccgaagagc tacaacgcgg agctgagagg cctatggatg
       61 aggaggacgc ggcggccccg gtttgttctc atgaacaaga tggatgacct caacttgcac
      121 taccggtttc tgaactggcg aaggaggatt cgggagatcc gagaggtccg ggccttccga
      181 tatcaggaga ggttcaagca tatccttgta gatggtgaca ctttgagtta ccatggaaat
      241 tctggtgaag ttggctgcta cgtggcgtct cgacccctga ccaaggacag caattatttt
      301 gaggtatcta tcgtggacag tggcgtccgg ggcaccattg ctgtggggct ggtccctcag
      361 tactacagct tggatcacca gcctggctgg ttgcctgact ccgtagccta ccatgctgat
      421 gatggcaagc tgtacaacgg ccgagccaag gggcgccagt tcgggtcaaa gtgcaactct
      481 ggggaccgga tcggctgtgg cattgagcct gtgtcctttg atgtgcagac tgcccagatc
      541 ttcttcacca aaaatgggaa acgggtgggc tccaccatca tgcccatgtc cccagatggg
      601 ctcttcccag cagttggtat gcattccctg ggcgaggagg taaggctgca cctcaatgcc
      661 gagctgggcc gtgaggatga cagcgtcatg atggtggaca gttacgagga tgaatggggc
      721 cggctgcatg acgtcagagt ctgtgggacg ctgctggagt atttggggaa gggcaagagc
      781 atcgtggatg tggggctggc tcaggctcgg cacccactga gcacccgcag ccattacttt
      841 gaggtggaga ttgtggatcc tggagagaag tgctatatcg ccttggggct ggcccggaag
      901 gattatccca agaacagaca ccctggctgg agcagagggt ctgtggccta ccacgcagat
      961 gacgggaaga tcttccatgg cagtggtgtg ggggacccct ttgggccacg ctgctacaaa
     1021 ggagacatta tgggctgtgg aatcatgttc ccccgggact acattctgga cagcgagggg
     1081 gatagtgatg acagttgtga cacagtgatc ttgtccccga ctgcccgggc tgtccggaac
     1141 gtccgaaatg tcatgtacct gcaccaggaa ggggaagagg aagaggagga agaggaggaa
     1201 gaggaggatg gggaagagat cgagcaggag catgagggca agaaggtggt ggtcttcttc
     1261 actcggaatg gcaagatcat cgggaagaag gatgctgttg tgccgtctgg aggtttcttt
     1321 cctaccattg gcatgctcag ttgtggggag aaagtgaaag tagacctgca ccccttgagt
     1381 ggctagtggg gtcaccagtc catctgccct ctccgtctgc attttctctc acagcaggcc
     1441 ctgggagggc atccccagtt tctgtcagct caggctgcac ctctctgtct ctgggcctga
     1501 gagcagtggt gggcccagag ggcagtattg atatgaatgg gaggagcccc ttgatcgggt
     1561 taatcggtcc tggatcttct ttcacctcgc tgggcgttga gcaaactggg aggtataagc
     1621 ccacctgctg acctgattgg tatggtgctc tgccgagggt gagggtcgag tagaggcagt
     1681 ctgtccctgt ctaccacagc tccccgaatt ctcttcatcc cctctcctca tgtaagccag
     1741 ttgctgctgt ctccccctgg ctgggctagg gggcctgtct tggccatctc tcctttcact
     1801 ggctgctgtc ctaaaacaca tctagggtct ccattgtttt ctgagagatg gtcccaccct
     1861 caacccacag cagaaagcct gaacttggct tcctgcctgc tcacacgcaa ctgtgtgtgt
     1921 gtgtgagaga gagaggggct gtgtggtagc gtgggacttc agcctttgct gccatctcct
     1981 tgtctgcact cttcttcaaa gcacctctag ccctggctcc ccaggatgga gccaaggcac
     2041 cggggcatgt gttgtattgt ggctgtttgc ccagagcagc agcttggccc cttctttctc
     2101 ttcacctacc caccccccac cctgtgcccc agcttgctgc ttgtgccagt tgacgtttct
     2161 gctccagtgt ttgattctag tgtctatata gaccccccaa ccagcccccc tcttcccgtt
     2221 tcctgagctc ctccatccca tcaacaggga gagaagcagc cggagctctt ggtctcagtt
     2281 tgcacagtgg gtagggctgg ggagggggtt tgttgtcgtg ctgctggggc tccccttgcc
     2341 cctcgtttcg ggccctgcac tatgatatat gaaatgtatg tacagatcag agatgtttat
     2401 acagccaata aagacggagt ttccgtattt atcaggaaaa aaaaaaaaaa aaaa
//
