LOCUS       NM_011472                614 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus small proline-rich protein 2F (Sprr2f), mRNA.
ACCESSION   NM_011472
VERSION     NM_011472.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 614)
  AUTHORS   Huynh,K.M., Wong,A.C., Wu,B., Horschman,M., Zhao,H. and Brooks,J.D.
  TITLE     Sprr2f protects against renal injury by decreasing the level of
            reactive oxygen species in female mice
  JOURNAL   Am J Physiol Renal Physiol 319 (5), F876-F884 (2020)
   PUBMED   33017192
  REMARK    GeneRIF: Sprr2f protects against renal injury by decreasing the
            level of reactive oxygen species in female mice.
REFERENCE   2  (bases 1 to 614)
  AUTHORS   Rutledge,E.A., Benazet,J.D. and McMahon,A.P.
  TITLE     Cellular heterogeneity in the ureteric progenitor niche and
            distinct profiles of branching morphogenesis in organ development
  JOURNAL   Development 144 (17), 3177-3188 (2017)
   PUBMED   28705898
REFERENCE   3  (bases 1 to 614)
  AUTHORS   Kumar,V., Bouameur,J.E., Bar,J., Rice,R.H., Hornig-Do,H.T.,
            Roop,D.R., Schwarz,N., Brodesser,S., Thiering,S., Leube,R.E.,
            Wiesner,R.J., Vijayaraj,P., Brazel,C.B., Heller,S., Binder,H.,
            Loffler-Wirth,H., Seibel,P. and Magin,T.M.
  TITLE     A keratin scaffold regulates epidermal barrier formation,
            mitochondrial lipid composition, and activity
  JOURNAL   J Cell Biol 211 (5), 1057-1075 (2015)
   PUBMED   26644517
  REMARK    Erratum:[J Cell Biol. 2016 Mar 28;212(7):877. doi:
            10.1083/jcb.20140414703042016c.. PMID: 27002167]
REFERENCE   4  (bases 1 to 614)
  AUTHORS   Gunschmann,C., Stachelscheid,H., Akyuz,M.D., Schmitz,A.,
            Missero,C., Bruning,J.C. and Niessen,C.M.
  TITLE     Insulin/IGF-1 controls epidermal morphogenesis via regulation of
            FoxO-mediated p63 inhibition
  JOURNAL   Dev Cell 26 (2), 176-187 (2013)
   PUBMED   23906066
REFERENCE   5  (bases 1 to 614)
  AUTHORS   Nagarajan,P., Chin,S.S., Wang,D., Liu,S., Sinha,S. and
            Garrett-Sinha,L.A.
  TITLE     Ets1 blocks terminal differentiation of keratinocytes and induces
            expression of matrix metalloproteases and innate immune mediators
  JOURNAL   J Cell Sci 123 (Pt 20), 3566-3575 (2010)
   PUBMED   20930145
REFERENCE   6  (bases 1 to 614)
  AUTHORS   Martin,N., Patel,S. and Segre,J.A.
  TITLE     Long-range comparison of human and mouse Sprr loci to identify
            conserved noncoding sequences involved in coordinate regulation
  JOURNAL   Genome Res 14 (12), 2430-2438 (2004)
   PUBMED   15574822
REFERENCE   7  (bases 1 to 614)
  AUTHORS   Hong,S.H., Nah,H.Y., Lee,J.Y., Lee,Y.J., Lee,J.W., Gye,M.C.,
            Kim,C.H., Kang,B.M. and Kim,M.K.
  TITLE     Estrogen regulates the expression of the small proline-rich 2 gene
            family in the mouse uterus
  JOURNAL   Mol Cells 17 (3), 477-484 (2004)
   PUBMED   15232223
REFERENCE   8  (bases 1 to 614)
  AUTHORS   Patel,S., Kartasova,T. and Segre,J.A.
  TITLE     Mouse Sprr locus: a tandem array of coordinately regulated genes
  JOURNAL   Mamm Genome 14 (2), 140-148 (2003)
   PUBMED   12584609
REFERENCE   9  (bases 1 to 614)
  AUTHORS   Song,H.J., Poy,G., Darwiche,N., Lichti,U., Kuroki,T., Steinert,P.M.
            and Kartasova,T.
  TITLE     Mouse Sprr2 genes: a clustered family of genes showing differential
            expression in epithelial tissues
  JOURNAL   Genomics 55 (1), 28-42 (1999)
   PUBMED   9888996
REFERENCE   10 (bases 1 to 614)
  AUTHORS   Gibbs,S., Fijneman,R., Wiegant,J., van Kessel,A.G., van De Putte,P.
            and Backendorf,C.
  TITLE     Molecular characterization and evolution of the SPRR family of
            keratinocyte differentiation markers encoding small proline-rich
            proteins
  JOURNAL   Genomics 16 (3), 630-637 (1993)
   PUBMED   8325635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129296.2.
            
            On Jun 28, 2022 this sequence version replaced NM_011472.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY158990.1, CJ043432.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                AC129296.2         136247-136288
            43-614              AC129296.2         136936-137507
FEATURES             Location/Qualifiers
     source          1..614
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.14 cM"
     gene            1..614
                     /gene="Sprr2f"
                     /note="small proline-rich protein 2F"
                     /db_xref="GeneID:20760"
                     /db_xref="MGI:MGI:1330349"
     exon            1..42
                     /gene="Sprr2f"
                     /inference="alignment:Splign:2.1.0"
     exon            43..614
                     /gene="Sprr2f"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..293
                     /gene="Sprr2f"
                     /codon_start=1
                     /product="small proline-rich protein 2F"
                     /protein_id="NP_035602.1"
                     /db_xref="CCDS:CCDS57226.1"
                     /db_xref="GeneID:20760"
                     /db_xref="MGI:MGI:1330349"
                     /translation="MSYQEQQCKQPCQPPPVCPPPKCPEPCSPSVCPEPCPPPKCPEP
                     CPEPCPPPSFQQKCPPVQPPPPCQQKCPPKSK"
     regulatory      592..597
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sprr2f"
                     /note="hexamer: AATAAA"
     polyA_site      614
                     /gene="Sprr2f"
                     /note="major polyA site"
ORIGIN      
        1 agactcctgg tacacacgtc ctggaatact ttggagaacc tgatcctgag gcttcagcaa
       61 caatgtctta ccaagaacag cagtgcaagc aaccctgcca gcctcctcct gtgtgtccac
      121 caccaaagtg cccagagcct tgttctccct cggtgtgccc tgagccttgt cctcctccaa
      181 agtgccctga gccttgtcct gagccatgtc cccctccctc attccagcag aaatgccctc
      241 ctgtgcaacc tcctccaccc tgccagcaga agtgcccacc caagagcaag tgaagtcttc
      301 agcagtcttc aggacagggg aaagagaaaa gaatctattt catgtcattc catagcaaca
      361 ccttatcttc cctccaaagt ctgacatgga tgcagaagaa ttttctctac ccttcaccta
      421 cttccatatc tcagtgatga cctctaataa gtaatgaatt tgcccgagac tataatcttg
      481 ctgctgtaaa ggggctctag agaatgggtc ttgttccatt gttcagtatg acatttttca
      541 aatctctctg tcacttgagc agggtagttg ttactgttgt tttatttccc aaataaagta
      601 ctatgtttta atga
//
