LOCUS       NM_011471                648 bp    mRNA    linear   ROD 13-JUN-2024
DEFINITION  Mus musculus small proline-rich protein 2E (Sprr2e), mRNA.
ACCESSION   NM_011471
VERSION     NM_011471.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 648)
  AUTHORS   Inoue,S.I., Takahara,S., Yoshikawa,T., Niihori,T., Yanai,K.,
            Matsubara,Y. and Aoki,Y.
  TITLE     Activated Braf induces esophageal dilation and gastric epithelial
            hyperplasia in mice
  JOURNAL   Hum Mol Genet 26 (23), 4715-4727 (2017)
   PUBMED   28973166
REFERENCE   2  (bases 1 to 648)
  AUTHORS   Bebee,T.W., Park,J.W., Sheridan,K.I., Warzecha,C.C., Cieply,B.W.,
            Rohacek,A.M., Xing,Y. and Carstens,R.P.
  TITLE     The splicing regulators Esrp1 and Esrp2 direct an epithelial
            splicing program essential for mammalian development
  JOURNAL   Elife 4, e08954 (2015)
   PUBMED   26371508
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 648)
  AUTHORS   Martin,N., Patel,S. and Segre,J.A.
  TITLE     Long-range comparison of human and mouse Sprr loci to identify
            conserved noncoding sequences involved in coordinate regulation
  JOURNAL   Genome Res 14 (12), 2430-2438 (2004)
   PUBMED   15574822
REFERENCE   4  (bases 1 to 648)
  AUTHORS   Hong,S.H., Nah,H.Y., Lee,J.Y., Lee,Y.J., Lee,J.W., Gye,M.C.,
            Kim,C.H., Kang,B.M. and Kim,M.K.
  TITLE     Estrogen regulates the expression of the small proline-rich 2 gene
            family in the mouse uterus
  JOURNAL   Mol Cells 17 (3), 477-484 (2004)
   PUBMED   15232223
REFERENCE   5  (bases 1 to 648)
  AUTHORS   Patel,S., Kartasova,T. and Segre,J.A.
  TITLE     Mouse Sprr locus: a tandem array of coordinately regulated genes
  JOURNAL   Mamm Genome 14 (2), 140-148 (2003)
   PUBMED   12584609
REFERENCE   6  (bases 1 to 648)
  AUTHORS   Song,H.J., Poy,G., Darwiche,N., Lichti,U., Kuroki,T., Steinert,P.M.
            and Kartasova,T.
  TITLE     Mouse Sprr2 genes: a clustered family of genes showing differential
            expression in epithelial tissues
  JOURNAL   Genomics 55 (1), 28-42 (1999)
   PUBMED   9888996
REFERENCE   7  (bases 1 to 648)
  AUTHORS   Gibbs,S., Fijneman,R., Wiegant,J., van Kessel,A.G., van De Putte,P.
            and Backendorf,C.
  TITLE     Molecular characterization and evolution of the SPRR family of
            keratinocyte differentiation markers encoding small proline-rich
            proteins
  JOURNAL   Genomics 16 (3), 630-637 (1993)
   PUBMED   8325635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC129296.2.
            
            On Jul 1, 2022 this sequence version replaced NM_011471.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY158989.1, SRR17253013.1454833.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                AC129296.2         123203-123244
            43-648              AC129296.2         123905-124510
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.14 cM"
     gene            1..648
                     /gene="Sprr2e"
                     /note="small proline-rich protein 2E"
                     /db_xref="GeneID:20759"
                     /db_xref="MGI:MGI:1330346"
     exon            1..42
                     /gene="Sprr2e"
                     /inference="alignment:Splign:2.1.0"
     exon            43..648
                     /gene="Sprr2e"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..292
                     /gene="Sprr2e"
                     /codon_start=1
                     /product="small proline-rich protein 2E"
                     /protein_id="NP_035601.1"
                     /db_xref="CCDS:CCDS57225.1"
                     /db_xref="GeneID:20759"
                     /db_xref="MGI:MGI:1330346"
                     /translation="MSYQQQQCKQPCQPPPVCPPKKCPEPCPHPQCPEPCPPPKCPEP
                     CPEPCPPPSYQQKCPPVQPPPPCQQKCPPKSK"
     regulatory      623..628
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sprr2e"
                     /note="hexamer: AATAAA"
     polyA_site      648
                     /gene="Sprr2e"
                     /note="major polyA site"
ORIGIN      
        1 agactcctgg tactcaggtc ctaggctact ttggagaacc tgatcctgag aattcagcac
       61 tatgtcttac caacagcagc agtgcaagca gccttgccag cctccacctg tgtgcccacc
      121 caagaagtgc cctgagcctt gtcctcatcc acagtgtcct gagccttgtc ctcctccaaa
      181 gtgccctgag ccttgtcctg agccatgtcc tcctccctca taccagcaga aatgccctcc
      241 tgtgcaacct cctccaccat gtcaacagaa gtgcccaccc aagagcaagt gagggattca
      301 gcagtcatcg ggacaagggg aagagaagag aatctatctc atgtacttcc aaagcaacac
      361 ctccatcttc cctccaaagg ctgtcatggg tgaatcctct ctacctgtca ctcccatttg
      421 cctgtaatga cctcttttag ggaaggcatt ttccttaggt tgtcctgcca tttctctcat
      481 acaggctgct gattatatgt tctcaagttg ttcagtgtcc caaatgctca gaaagaataa
      541 cacctgctgt ctatcctgtg cacccagaag atgttttcca aaactgtcaa ttgttgtgtt
      601 gtcattgttg tttcatttcc tgaataaagc acaatctgct taatggta
//
