LOCUS       NM_009265                821 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus small proline-rich protein 1B (Sprr1b), mRNA.
ACCESSION   NM_009265
VERSION     NM_009265.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 821)
  AUTHORS   Butera,A., Agostini,M., Cassandri,M., De Nicola,F., Fanciulli,M.,
            D'Ambrosio,L., Falasca,L., Nardacci,R., Wang,L., Piacentini,M.,
            Knight,R.A., Jia,W., Sun,Q., Shi,Y., Wang,Y., Candi,E. and
            Melino,G.
  TITLE     ZFP750 affects the cutaneous barrier through regulating lipid
            metabolism
  JOURNAL   Sci Adv 9 (17), eadg5423 (2023)
   PUBMED   37115925
REFERENCE   3  (bases 1 to 821)
  AUTHORS   Zhang,M., Wang,X., Guo,F., Jia,Q., Liu,N., Chen,Y., Yan,Y.,
            Huang,M., Tang,H., Deng,Y., Huang,S., Zhou,Z., Zhang,L. and
            Zhang,L.
  TITLE     Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by
            Regulating Intercellular Junctions and Keratinization of Epidermal
            Cells during Mouse Skin Development
  JOURNAL   Theranostics 9 (17), 5065-5084 (2019)
   PUBMED   31410202
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 821)
  AUTHORS   Inoue,S.I., Takahara,S., Yoshikawa,T., Niihori,T., Yanai,K.,
            Matsubara,Y. and Aoki,Y.
  TITLE     Activated Braf induces esophageal dilation and gastric epithelial
            hyperplasia in mice
  JOURNAL   Hum Mol Genet 26 (23), 4715-4727 (2017)
   PUBMED   28973166
REFERENCE   5  (bases 1 to 821)
  AUTHORS   Miyai,M., Hamada,M., Moriguchi,T., Hiruma,J., Kamitani-Kawamoto,A.,
            Watanabe,H., Hara-Chikuma,M., Takahashi,K., Takahashi,S. and
            Kataoka,K.
  TITLE     Transcription Factor MafB Coordinates Epidermal Keratinocyte
            Differentiation
  JOURNAL   J Invest Dermatol 136 (9), 1848-1857 (2016)
   PUBMED   27208706
  REMARK    Review article
REFERENCE   6  (bases 1 to 821)
  AUTHORS   Tesfaigzi,Y., Wright,P.S. and Belinsky,S.A.
  TITLE     SPRR1B overexpression enhances entry of cells into the G0 phase of
            the cell cycle
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 285 (4), L889-L898 (2003)
   PUBMED   12832281
  REMARK    GeneRIF: SPRR1B expression pattern in nonsquamous tumors; findings
            indicate SPRR1B likely coupled to signals responsible for
            withdrawal from the proliferative state; overexpression for
            prolonged periods may disrupt normal progression of mitosis
REFERENCE   7  (bases 1 to 821)
  AUTHORS   Patel,S., Kartasova,T. and Segre,J.A.
  TITLE     Mouse Sprr locus: a tandem array of coordinately regulated genes
  JOURNAL   Mamm Genome 14 (2), 140-148 (2003)
   PUBMED   12584609
REFERENCE   8  (bases 1 to 821)
  AUTHORS   Lueders,K.K., Elliott,R.W., Marenholz,I., Mischke,D., DuPree,M. and
            Hamer,D.
  TITLE     Genomic organization and mapping of the human and mouse neuronal
            beta2-nicotinic acetylcholine receptor genes
  JOURNAL   Mamm Genome 10 (9), 900-905 (1999)
   PUBMED   10441742
REFERENCE   9  (bases 1 to 821)
  AUTHORS   Reddy,S.P., Konkin,T. and Wu,R.
  TITLE     Structure and organization of the genes encoding mouse small
            proline-rich proteins, mSPRR1A and 1B
  JOURNAL   Gene 224 (1-2), 59-66 (1998)
   PUBMED   9931436
REFERENCE   10 (bases 1 to 821)
  AUTHORS   Kartasova,T., Darwiche,N., Kohno,Y., Koizumi,H., Osada,S., Huh,N.,
            Lichti,U., Steinert,P.M. and Kuroki,T.
  TITLE     Sequence and expression patterns of mouse SPR1: Correlation of
            expression with epithelial function
  JOURNAL   J Invest Dermatol 106 (2), 294-304 (1996)
   PUBMED   8601731
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127036.3.
            
            On Jun 27, 2022 this sequence version replaced NM_009265.4.
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK003398.1, AK009752.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                AC127036.3         102105-102146       c
            43-821              AC127036.3         100175-100953       c
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.14 cM"
     gene            1..821
                     /gene="Sprr1b"
                     /note="small proline-rich protein 1B"
                     /db_xref="GeneID:20754"
                     /db_xref="MGI:MGI:106659"
     exon            1..42
                     /gene="Sprr1b"
                     /inference="alignment:Splign:2.1.0"
     exon            43..821
                     /gene="Sprr1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..523
                     /gene="Sprr1b"
                     /note="SPR1B; SPR1 B"
                     /codon_start=1
                     /product="cornifin-B"
                     /protein_id="NP_033291.1"
                     /db_xref="CCDS:CCDS17557.1"
                     /db_xref="GeneID:20754"
                     /db_xref="MGI:MGI:106659"
                     /translation="MSSHQQKQPCTAPPQLHEQQVKQPCQPPPPEPCVSQVKTPCDTK
                     VPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAPEPCHPKAP
                     EPCHPKAPEPCHPKVPEPCLPKAPEPCQPIVPEPCPSTVTPILAQQKTKQK"
     regulatory      800..805
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Sprr1b"
                     /note="hexamer: ATTAAA"
     polyA_site      821
                     /gene="Sprr1b"
                     /note="major polyA site"
ORIGIN      
        1 atccgatccc agcgaccaca ctacctgtcc tccatatacc aggctcatcc atctttgaag
       61 catgagttca catcagcaga agcagccctg cacagctcct ccacagttgc atgagcaaca
      121 agtgaaacag ccttgccagc caccacctcc tgagccatgt gtctcacaag tcaagacacc
      181 ctgtgacacc aaggttcctg agccctgcca ccccaaggct cctgagccct gccatcccaa
      241 ggctcctgag ccctgccacc ccaaggctcc tgagccctgc caccccaagg ctcctgagcc
      301 ctgccacccc aaggctcctg agccctgcca ccccaaggct cctgaaccct gccaccccaa
      361 ggctcctgag ccctgccacc ccaaggctcc tgagccctgc caccccaagg ttcctgagcc
      421 ctgccttccc aaggctcctg agccctgcca acccattgtt cctgagccct gtccctcaac
      481 tgtcactcca atactagccc aacagaagac aaagcaaaag tagtgcccaa aagctgtgcc
      541 ttggggagat gatcaacaat agatgctgag cctcaatttg cattctgttt gaatatacta
      601 tgccctaata tcacagtccc acttctcatt tatattttaa aattaagtac tacaaagttt
      661 ttttttttaa tcctattaat gttggggctc tgggtctcag aattcacccg agaacttggt
      721 agctgagcta gtttgtccat tcagaatttt ttcccgaaaa gagaccaagt tacaagtgat
      781 tgggttcttt tatgttccta ttaaatctcc ttacattcct a
//
