LOCUS       NM_145584               6166 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus spondin 1, (f-spondin) extracellular matrix protein
            (Spon1), mRNA.
ACCESSION   NM_145584
VERSION     NM_145584.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6166)
  AUTHORS   Choi,J.S., Ayupe,A.C., Beckedorff,F., Catanuto,P., McCartan,R.,
            Levay,K. and Park,K.K.
  TITLE     Single-nucleus RNA sequencing of developing superior colliculus
            identifies neuronal diversity and candidate mediators of circuit
            assembly
  JOURNAL   Cell Rep 42 (9), 113037 (2023)
   PUBMED   37624694
REFERENCE   2  (bases 1 to 6166)
  AUTHORS   van de Haar,L.L., Riga,D., Boer,J.E., Garritsen,O., Adolfs,Y.,
            Sieburgh,T.E., van Dijk,R.E., Watanabe,K., van Kronenburg,N.C.H.,
            Broekhoven,M.H., Posthuma,D., Meye,F.J., Basak,O. and
            Pasterkamp,R.J.
  TITLE     Molecular signatures and cellular diversity during mouse habenula
            development
  JOURNAL   Cell Rep 40 (1), 111029 (2022)
   PUBMED   35793630
REFERENCE   3  (bases 1 to 6166)
  AUTHORS   Neupane,S., Goto,J., Berardinelli,S.J., Ito,A., Haltiwanger,R.S.
            and Holdener,B.C.
  TITLE     Hydrocephalus in mouse B3glct mutants is likely caused by defects
            in multiple B3GLCT substrates in ependymal cells and subcommissural
            organ
  JOURNAL   Glycobiology 31 (8), 988-1004 (2021)
   PUBMED   33909046
REFERENCE   4  (bases 1 to 6166)
  AUTHORS   La Manno,G., Siletti,K., Furlan,A., Gyllborg,D., Vinsland,E., Mossi
            Albiach,A., Mattsson Langseth,C., Khven,I., Lederer,A.R.,
            Dratva,L.M., Johnsson,A., Nilsson,M., Lonnerberg,P. and
            Linnarsson,S.
  TITLE     Molecular architecture of the developing mouse brain
  JOURNAL   Nature 596 (7870), 92-96 (2021)
   PUBMED   34321664
REFERENCE   5  (bases 1 to 6166)
  AUTHORS   Xu,J., Liu,H., Lan,Y. and Jiang,R.
  TITLE     Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene
            Expression in Palate Development
  JOURNAL   Front Cell Dev Biol 9, 665109 (2021)
   PUBMED   33898467
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6166)
  AUTHORS   Miyamoto,K., Morishita,Y., Yamazaki,M., Minamino,N., Kangawa,K.,
            Matsuo,H., Mizutani,T., Yamada,K. and Minegishi,T.
  TITLE     Isolation and characterization of vascular smooth muscle cell
            growth promoting factor from bovine ovarian follicular fluid and
            its cDNA cloning from bovine and human ovary
  JOURNAL   Arch Biochem Biophys 390 (1), 93-100 (2001)
   PUBMED   11368520
REFERENCE   7  (bases 1 to 6166)
  AUTHORS   Feinstein,Y., Borrell,V., Garcia,C., Burstyn-Cohen,T., Tzarfaty,V.,
            Frumkin,A., Nose,A., Okamoto,H., Higashijima,S., Soriano,E. and
            Klar,A.
  TITLE     F-spondin and mindin: two structurally and functionally related
            genes expressed in the hippocampus that promote outgrowth of
            embryonic hippocampal neurons
  JOURNAL   Development 126 (16), 3637-3648 (1999)
   PUBMED   10409509
REFERENCE   8  (bases 1 to 6166)
  AUTHORS   Serafini,T., Colamarino,S.A., Leonardo,E.D., Wang,H.,
            Beddington,R., Skarnes,W.C. and Tessier-Lavigne,M.
  TITLE     Netrin-1 is required for commissural axon guidance in the
            developing vertebrate nervous system
  JOURNAL   Cell 87 (6), 1001-1014 (1996)
   PUBMED   8978605
REFERENCE   9  (bases 1 to 6166)
  AUTHORS   Fan,C.M., Kuwana,E., Bulfone,A., Fletcher,C.F., Copeland,N.G.,
            Jenkins,N.A., Crews,S., Martinez,S., Puelles,L., Rubenstein,J.L.
            and Tessier-Lavigne,M.
  TITLE     Expression patterns of two murine homologs of Drosophila
            single-minded suggest possible roles in embryonic patterning and in
            the pathogenesis of Down syndrome
  JOURNAL   Mol Cell Neurosci 7 (1), 1-16 (1996)
   PUBMED   8812055
  REMARK    Erratum:[Mol Cell Neurosci 1996 Jun;7(6):519]
REFERENCE   10 (bases 1 to 6166)
  AUTHORS   Guillemot,F., Lo,L.C., Johnson,J.E., Auerbach,A., Anderson,D.J. and
            Joyner,A.L.
  TITLE     Mammalian achaete-scute homolog 1 is required for the early
            development of olfactory and autonomic neurons
  JOURNAL   Cell 75 (3), 463-476 (1993)
   PUBMED   8221886
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158213.4, AC118201.8 and AC102861.12.
            
            On Jul 30, 2009 this sequence version replaced NM_145584.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC020531.1, AK146506.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-569               AC158213.4         89608-90176         c
            570-676             AC158213.4         67622-67728         c
            677-810             AC158213.4         19222-19355         c
            811-884             AC118201.8         138731-138804       c
            885-1007            AC118201.8         131087-131209       c
            1008-1156           AC118201.8         90121-90269         c
            1157-1221           AC102861.12        157175-157239       c
            1222-1423           AC102861.12        144862-145063       c
            1424-1564           AC102861.12        143609-143749       c
            1565-1640           AC102861.12        143116-143191       c
            1641-1823           AC102861.12        142017-142199       c
            1824-1994           AC102861.12        140858-141028       c
            1995-2162           AC102861.12        140603-140770       c
            2163-2327           AC102861.12        139645-139809       c
            2328-2591           AC102861.12        137152-137415       c
            2592-6166           AC102861.12        130589-134163       c
FEATURES             Location/Qualifiers
     source          1..6166
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 59.25 cM"
     gene            1..6166
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /note="spondin 1, (f-spondin) extracellular matrix
                     protein"
                     /db_xref="GeneID:233744"
                     /db_xref="MGI:MGI:2385287"
     exon            1..569
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            570..676
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            677..810
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            811..884
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1007
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1156
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1157..1221
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1423
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1564
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1640
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..1823
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1824..1994
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2162
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            2163..2327
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            2328..2591
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     exon            2592..6166
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5197..5202
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /note="hexamer: CATAAA"
     polyA_site      5218
                     /gene="Spon1"
                     /gene_synonym="D330035F22Rik; FSP"
                     /note="major polyA site"
ORIGIN      
        1 cagaccctgg gaatccagct tcacaaaaca aacaccagag cgcccgctaa tcgccagctc
       61 agaaacaaaa cagcactgcg ctgggggatc cgggcgcaaa tcagccctcc ctcttcgcgc
      121 tccttcgcca ccgcccgccc ctcagctccg ctgctcggct ccgctcagag cagcgcagct
      181 ccgcagccgc caaagcgagg cgggcacggt ctccccaccg ccagcgccac ccgggctcct
      241 ccaggtttcg cctctgcagc tcccgtcact tggagcagga gtgtcctgac agggtctgca
      301 acatccgcat aaagttgggg ggccctcgag gatgaggctg tctcccgtgt ccctgaggct
      361 tagccggggt ccggcgctgc tggccctcgc gctgcccctg gccgcagcgc tagctttctc
      421 agatgagacc ctggacaaag tgaccaagtc ggagggctac tgcagccgca tcttgcgcgc
      481 ccagggcaca cggcgtgagg gatacacgga gttcagcctc cgcgtggaag gcgaccctga
      541 cttctataag ccaggaagca gctaccgagt gacactttcg gctgctcctc cctcctactt
      601 cagaggtttc acgttaattg ccctcaaaga gaaccaggag ggagataagg aagaagatca
      661 tgcaggcacc ttccagatca tagatgagga agagacccag tttatgagta actgtcctgt
      721 ggccgtcact gaaagcaccc ctcggaggag gacacggatc caggtgtttt ggatagcgcc
      781 accaacaggg acaggctgtg tgattctgaa ggccagcatt gtacagaaac gcataattta
      841 ttttcaagac gagggctccc tgaccaagaa gctgtgtgaa caggatccca cacttgatgg
      901 ggtgacggac agacccatct tagactgctg cgcctgtgga actgccaagt acagactcac
      961 gttttatggg aactggtccg agaagactca tccgaaggat taccctcgtc gggctaacca
     1021 ctggtctgcc atcattggtg ggtcccactc caagaactac gtgctgtggg agtatggagg
     1081 gtatgccagc gaaggggtca agcaagttgc tgaactgggc tcaccagtaa aaatggagga
     1141 agaaattcga caacagagtg atgaagtcct cactgtcatc aaagccaaag cccagtggcc
     1201 agcctggcag cctgtcaatg tgagagcagc accctcagct gaattctcag tggacaggac
     1261 acgccacttg atgtccttcc tcaccatgat gggccccagt ccagactgga acgtgggcct
     1321 atctgcagag gatctgtgca ccaaggagtg tggctgggtc cagaaagtag tgcaggacct
     1381 gattccctgg gatgctggca ctgacagcgg cgtgacctat gagtcaccaa acaagcccac
     1441 aattcctcag gaaaaaatcc gacccctgac tagtctggat catcctcaga gtcctttcta
     1501 tgacccagaa ggtgggtcca tcacacaagt ggccagagtc gtcatcgaga gaattgcccg
     1561 gaagggagaa cagtgcaaca ttgtacctga caacgtggac gatattgtag ccgacctggc
     1621 tccagaagag aaagatgaag atgacacccc tgaaacctgc atctactcca actggtcccc
     1681 atggtcggcc tgcagctctt ccacttgtga aaagggcaag aggatgcggc agcgcatgct
     1741 gaaggcacag ctggacctca gtgtcccctg tcctgacacc caggacttcc agccctgcat
     1801 gggcccaggc tgcagcgatg aagatggctc cacctgtacc atgtcggagt ggatcacctg
     1861 gtcgccctgt agcgtctcgt gcggcatggg catgaggtcc cgggagagat acgtgaagca
     1921 gttcccggaa gacggctcag tgtgcatgct gcccacggag gagacggaga agtgcacagt
     1981 caacgaggag tgctctccta gcagctgcct ggtgactgag tggggtgagt gggacgactg
     2041 cagtgccacc tgtgggatgg gtatgaagaa gaggcaccgt atggtcaaga tgagccccgc
     2101 ggacggctcc atgtgcaagg cagagacatc gcaggcggag aaatgcatga tgcctgagtg
     2161 ccataccatc ccgtgcttgc tgtctccctg gtccgagtgg agcgactgta gcgtgacctg
     2221 tgggaagggc atgcggaccc gccagcggat gctcaaatct ctggcagagc tgggtgactg
     2281 taacgaggac ctggagcagg cggagaagtg catgctgcca gaatgcccca ttgactgtga
     2341 actcagcgag tggtcccagt ggtctgaatg taacaagtca tgtgggaaag gtcacatgat
     2401 tcgaacccgg acaatccaaa tggaacctca gtttgggggt gtaccctgcc cagagactgt
     2461 gcaacgcaag aagtgccgca cccggaaatg ccttcgcagc ccatcagtcc agaagctgcg
     2521 ctggagggag gcccgagaga gcaggaggag tgagcagctg agagaagagt cagatggaga
     2581 gcagttccca ggctgtcgaa tgcgcccgtg gacagcctgg tcagaatgca ccaaactgtg
     2641 cggaggtggg atccaagagc gctacatgac tgtgaagaag aggttcaaaa gctcccagtt
     2701 taccagctgc aaagacaaga aggagatcag agcgtgcaac gtgcaccctt gttaatgggg
     2761 gttcaactcc ccacggccgc attccagatt ctagtcacca atggttgggt ggtttgtttg
     2821 cttgtgtaag atgatttcaa ttgtgtccac tagttttctt tctttttttt tttttattac
     2881 gatgtggttt gcccaatagt cttatgatgc caagggacag cctgtccgaa ttcttcttgg
     2941 tgagtgcagg ccaagtgggg catccttgtc ctcaggtggc cctcttccta cactgagtga
     3001 gtagtgttgg ctcaccttgt gtccctctgg aacatccccc tggtcaagca gggtgaagac
     3061 cctggccaca tccacaagga aaagcaacca tgttctcggg tgccagaatg cagcatgcag
     3121 gagacacagc catcaaatgc agaggacaga ttctcctctc tcatctgcgg cctgctcact
     3181 cttacagaaa cccgttcacc catctctttt tttatttagc acaactccag gtatcttggt
     3241 aagtctccag ggtcacgggt tcttcagtgc cctgaaggag gagctctaag gtaggggtgg
     3301 cgtttgttac aaacctcctg atactgcttt gttgacacca caagggtagc aggtgatgat
     3361 ggctacttta tttgtgagcc atgatttccg ttgagttctg attgttggtg ccataagtgt
     3421 ccgagggtgc cggacggacg cactaacctt ttctcggcag atccttctct gagccaatgc
     3481 agacggtcta ctgggcactg gttccaaagc caccctaaaa tcttcctaca catatgcaaa
     3541 ccttttaggt tccccaatct tccttagaat aaaacatttt agctctgaga actacctgat
     3601 aagtcggcca gagagccacc aagtcaatcc tcaacaaaaa taccatcttc cctacttaaa
     3661 agtttttttt aaagtcgtga tattttatag ttagaggaga gagagagaga gacaaactat
     3721 tcccatgact aagatacaaa cctacaagta agggttattc agtcatgcct gtgcctgatt
     3781 tctggaccag ggccctggtt ttcatggaca gtccagagga aagtcggggg tttccactga
     3841 tttccaagct atcagcagca cactaaaccc aggagtctaa gaaccaacag tcaagagtaa
     3901 gaggatgttg atctcagctg tgagctcatt agcaggtttt actcatgcat ctgttaaagc
     3961 taccaccaca tccttttgca agtctgttta ttaccgcttt atccaaatac atactgtggg
     4021 caagatgcac acagtgctat gaatacagta ctttaagaat ctccattcaa catatcagaa
     4081 tatgtccagc cacatctatg tacaacccct gaatatgtat tttccttaac acacgagagc
     4141 ctgttcaatt aaaaaaaaaa aaaaaagaaa agaaaagaaa atctcgctgg gtctgtcttt
     4201 gtttttagga ttattaagtg gtgggagagt tgggtctttt tccagttgct acctagttca
     4261 tttgcaggaa aagatggcgc ttctgtccct tctaggtggg ccgctgccat cacatccctc
     4321 agccacctgg attatttcca atgctatttt tagattaatg aattgctttc tccttcaaag
     4381 gagtacaaaa caaagaaatg agaggcttgg atttccaccc tccccataaa tgctctgcta
     4441 aaggatctgt cccgcctact ttgcaacatc ctcctagtgg tcttgtcaac ttatcctcaa
     4501 accatgacaa tctaagctcc ttcagatggt ggcaggcttc gctagcagct tgggttttca
     4561 cccagtccca cttgggtata attttaaccc tggttttgga gactttttta aaaaccagaa
     4621 aactgactaa agagaacaag aaacatgctt tcgtcatgaa ctacattgct ccgtttgtaa
     4681 tggggagatt gtgaatgtca aatctttcct gccaaaagcc ttgagttagg tggttgtcac
     4741 ttttctggct aaccaatcat tttggaaata aagatttttc ttactatgag tgaactctga
     4801 ctggacttcc accctggcga gtaacaactt gccacgtaaa gaaaactaga gccaggcgtg
     4861 gcagtgtgca ctcaatcaaa gaaaatttta attgtatata tattttacac caaccccaaa
     4921 ccagctgtaa tctggtcaaa cccacattgt aagatgtttc ccaatcagat attgagtcaa
     4981 tttcctatca ccatgccaat gtgttttatc agagggcaat ctactgaagc tactgagact
     5041 aaaacctggc ctccttcccc cctgaagtga aaaggttaaa agactctgtg ctgtgctttc
     5101 tttgcaaggt ctgcctgcaa gcagcagaac gggcacactt tcttggatgc cttctgcact
     5161 ctggaaaccc atcacaaccc gtctattgta tcaatacata aacattctct ctgtcaaatt
     5221 accgctgtgc tctgttttca ttaagcctcc atgttttaga caataacaag ttaaaaacaa
     5281 aattttggat catgcatggt ggaagctata ttctcagaac tagagaaact gtcccaagcc
     5341 agcaaaggtt gttgaagtca gaaaactcta agagctacat ttttgacagt ctgacctgaa
     5401 gttttcaaag cctggcttta gaaaattctg ttacatggaa ttatctatga agaagtaaaa
     5461 tatttatacc ctaaaaaaat gcatactatt atccaaacaa gactaaacca taaatgttta
     5521 attcctactt aaaactccga atcaaggaag ccagccattt ccaccatgtt gctacttggc
     5581 aaggtcgatt tcaatatccc cattcttctt gttcatattg cccaaagtag acagaatgaa
     5641 cataaattcc ctttgaaaaa tgattgaaat gcagtaacga attataaata gcagctacat
     5701 gttaattagc acggggctaa ttctccgatt tagatcctgt ggaaaaatga aagcaaaaca
     5761 tccatattaa aatgtcacat ttaaatgacg gtgcctgctt tcgaaccccc atgggctcag
     5821 aggcgatgta tgtatccaat gcatgtatcc agggacagaa gggcaaggac agtaatggtg
     5881 gggcccaggg aatctgggtt ggcacctgag cagctgtgac agccggccca ggtgggtcct
     5941 gctgttctgg tgtcaggact gacctccgag ccttacccct cgccttcaca gtttaccaag
     6001 ttctcacgca gagagtgggt ctcccagcag ccagctctac tccacctgcc cctcactgct
     6061 ttgtagtgca cacctttgta ctgaatctga cgagagctgc attttggtca tctgtaactg
     6121 aaaatgtctc gacaaataaa atttgcatac ataattttta acagtt
//
