LOCUS       NM_029932               1819 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus SPNS lysolipid transporter 3, sphingosine-1-phosphate
            (putative) (Spns3), mRNA.
ACCESSION   NM_029932 XM_126365
VERSION     NM_029932.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1819)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1819)
  AUTHORS   Jacobsson,J.A., Haitina,T., Lindblom,J. and Fredriksson,R.
  TITLE     Identification of six putative human transporters with structural
            similarity to the drug transporter SLC22 family
  JOURNAL   Genomics 90 (5), 595-609 (2007)
   PUBMED   17714910
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL662812.12.
            
            On May 1, 2007 this sequence version replaced NM_029932.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK020683.1, AK156479.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-249               AL662812.12        167689-167937       c
            250-315             AL662812.12        163579-163644       c
            316-452             AL662812.12        158106-158242       c
            453-604             AL662812.12        156726-156877       c
            605-671             AL662812.12        156015-156081       c
            672-820             AL662812.12        154862-155010       c
            821-973             AL662812.12        154219-154371       c
            974-1163            AL662812.12        147225-147414       c
            1164-1229           AL662812.12        122747-122812       c
            1230-1328           AL662812.12        117329-117427       c
            1329-1500           AL662812.12        117046-117217       c
            1501-1819           AL662812.12        115847-116165       c
FEATURES             Location/Qualifiers
     source          1..1819
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 44.34 cM"
     gene            1..1819
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /note="SPNS lysolipid transporter 3,
                     sphingosine-1-phosphate (putative)"
                     /db_xref="GeneID:77577"
                     /db_xref="MGI:MGI:1924827"
     exon            1..249
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1583
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /note="spinster homolog 3"
                     /codon_start=1
                     /product="protein spinster homolog 3"
                     /protein_id="NP_084208.1"
                     /db_xref="CCDS:CCDS24987.1"
                     /db_xref="GeneID:77577"
                     /db_xref="MGI:MGI:1924827"
                     /translation="MSTECLKPQTGGPQSQSLSQGGQYGALASGTCLPPSTPVPWSLP
                     RWRAYLAAAVLCYINLLNYMNWFIIPGVLLDVQKYFHISDSHAGLLQTVFISCLLVSA
                     PVFGYLGDRYNRKAILSFGILLWSGAGLSSSFISYQYSWLFFLSRGFVGTGAASYSTI
                     APTVLGDLFVKDQRTCALAVFYIFIPVGSGLGYVLGSTVAELTGNWRWALRLMPCLDA
                     MALALLILLVPDVPRGAAEKQGEVAVRAPRSSWCEDVRYLGRNWSFVFSTLGVTAIAF
                     VTGALGFWAPKFLFEARVVHGLQLPCFQEQCHSQDSLIFGALTVATGIIGVMLGAEAS
                     RRYKKVNPRAEPLICASSLFATAPCLYLALILASRTLLASYVFLALGELLLSCNWAVV
                     ADILLSVVVPRCRGTAEALQITVAHVLGDAGSPYLTGLISSVLQAERPDSYLQHFLSL
                     QHSFLCCAFAIVLGGGFFLLTALHLEKDQARARQPGKGTLDSKDIASRNTESQGLLSG
                     TSTPTE"
     exon            250..315
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            316..452
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            453..604
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            605..671
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            672..820
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            821..973
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1163
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1164..1229
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1328
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1500
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1819
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1792..1797
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1816
                     /gene="Spns3"
                     /gene_synonym="9830002I17Rik"
                     /note="major polyA site"
ORIGIN      
        1 gttctgacag agaagttgca gttagcactg ctgaggggat gtccacagag tgtctcaaac
       61 ctcagacagg agggccacag agccagagcc tgagccaagg tgggcagtat ggggccttgg
      121 cttcaggtac gtgtctgcct ccctccacac ccgtcccctg gagcctgccc cgctggagag
      181 cttacttggc tgcagctgtt ctctgttaca tcaaccttct gaattacatg aactggttca
      241 tcatcccagg agtgttacta gatgtccaga agtattttca catcagtgac agccatgctg
      301 gtttgctgca gacagtcttc atcagctgcc tgctggtgtc tgcacctgtg tttggctacc
      361 tgggtgaccg atacaaccgc aaagccatac tgagcttcgg gatcctgctg tggtcagggg
      421 ctggcctctc cagctccttc atctcctacc agtattcctg gctcttcttc ctgtcccggg
      481 gattcgtggg taccggtgca gcaagctatt ccaccattgc acccactgtc ctgggagacc
      541 tcttcgtgaa ggaccagcgg acctgtgcac tggctgtctt ttacatcttc atccctgttg
      601 gaagtggtct gggctatgtg ctgggatcaa ctgtggcgga gctgacaggg aactggcgat
      661 gggccctccg actcatgccc tgcttggatg ccatggcctt ggctctgctc atcttgctgg
      721 ttccagacgt accccgagga gcagctgaga aacagggaga agtggctgtg agggctccga
      781 ggagcagctg gtgtgaggat gtcagatact tggggagaaa ctggagtttt gtgttttcaa
      841 cccttggagt gacagccata gcctttgtga ctggtgctct gggcttctgg gcacccaagt
      901 ttctgtttga agctcgcgtg gtgcatggcc tgcagctccc ctgcttccag gagcagtgcc
      961 acagccagga cagcctgatt tttggggcac tgaccgtggc aactggtatt attggtgtca
     1021 tgctgggggc agaggcctca agaaggtaca agaaggtgaa ccccagggct gagcccctca
     1081 tctgtgcttc tagtctgttt gccacagctc cctgcctcta cctggctctc atcttggcct
     1141 cacggaccct cctggcctcc tatgtgttcc tggccctcgg ggagctcctt ctgtcttgta
     1201 actgggcggt agttgctgat atcctgttgt ccgtggtggt gcccaggtgc cggggcacgg
     1261 cagaggcact ccagatcaca gtggctcacg tcctgggaga tgctggcagc ccctacctca
     1321 ctggacttat ctccagtgtc ctgcaggctg agcgccccga ctcctacctg cagcacttcc
     1381 tcagcctaca gcacagcttc ctgtgttgtg ccttcgccat agtgctaggt ggtggcttct
     1441 tcctgctgac tgcactgcac ctggaaaagg accaggcccg ggccaggcaa cctggcaaag
     1501 gaactctgga cagcaaggac atagccagca ggaacaccga gagccaaggg ctgctatctg
     1561 gcaccagcac cccaacagag tagccctgag cccctgcctt gcagtgagca ggctcaatcc
     1621 tacctacatc ctcctggggc ccccacccat cttggctgtg actcagggac cccacttttt
     1681 caatccctgc tagagagctg ccagggcgca ggagctggct ggattgagct gtcaccatcc
     1741 tttagggagt ctgggccctg tgtctacacc ctccagggag accaggccct tattaaagca
     1801 tgaccagtgc aaagccctc
//
