LOCUS       NM_026208                923 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus sperm microtubule inner protein 5 (Spmip5), transcript
            variant 1, mRNA.
ACCESSION   NM_026208
VERSION     NM_026208.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Zhou,L., Liu,H., Liu,S., Yang,X., Dong,Y., Pan,Y., Xiao,Z.,
            Zheng,B., Sun,Y., Huang,P., Zhang,X., Hu,J., Sun,R., Feng,S.,
            Zhu,Y., Liu,M., Gui,M. and Wu,J.
  TITLE     Structures of sperm flagellar doublet microtubules expand the
            genetic spectrum of male infertility
  JOURNAL   Cell 186 (13), 2897-2910 (2023)
   PUBMED   37295417
REFERENCE   2  (bases 1 to 923)
  AUTHORS   Miyata,H., Castaneda,J.M., Fujihara,Y., Yu,Z., Archambeault,D.R.,
            Isotani,A., Kiyozumi,D., Kriseman,M.L., Mashiko,D., Matsumura,T.,
            Matzuk,R.M., Mori,M., Noda,T., Oji,A., Okabe,M.,
            Prunskaite-Hyyrylainen,R., Ramirez-Solis,R., Satouh,Y., Zhang,Q.,
            Ikawa,M. and Matzuk,M.M.
  TITLE     Genome engineering uncovers 54 evolutionarily conserved and
            testis-enriched genes that are not required for male fertility in
            mice
  JOURNAL   Proc Natl Acad Sci U S A 113 (28), 7704-7710 (2016)
   PUBMED   27357688
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK006135.1.
            
            On Apr 6, 2007 this sequence version replaced NM_026208.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK006135.1, AK006423.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-923               AK006135.1         2-924
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 54.51 cM"
     gene            1..923
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /note="sperm microtubule inner protein 5"
                     /db_xref="GeneID:67507"
                     /db_xref="MGI:MGI:1914757"
     exon            1..34
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..730
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     uncharacterized protein C10orf82 homolog; sperm associated
                     microtubule inner protein 5"
                     /codon_start=1
                     /product="sperm-associated microtubule inner protein 5
                     isoform 1"
                     /protein_id="NP_080484.1"
                     /db_xref="CCDS:CCDS38031.1"
                     /db_xref="GeneID:67507"
                     /db_xref="MGI:MGI:1914757"
                     /translation="MLKPAESKMESPKTFMRKLPITPGYCGFIPWLSCQESSSEDRMN
                     PCVKAFQERTQRYKEDQQGLNCSVANTPPLKPICSEDTVLWVLHEYAKKYHPLTLECK
                     NEKKPLQEPPIPGWAGYLPRARVTEFGYATRYTIMAKKCYKDFLDLVEQAKRAQLKPY
                     EQTYDVRAAQPLSPSSKILQLQGLSPAFPEFSGPGQTPPSEDPQAPRPCGCAQWSSQS
                     CSRNVYGEPPSLAKAFAES"
     exon            35..95
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            96..314
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            315..501
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            502..599
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            600..923
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      921
                     /gene="Spmip5"
                     /gene_synonym="1700019N19Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcctggttcc ctggggatgc tcaagccagc ggagagtaaa atggagtctc ccaagacctt
       61 catgagaaag ctgcccatca ctccaggata ctgcggcttc ataccatggc tcagttgcca
      121 ggaaagctcc agcgaggacc gcatgaatcc ctgtgtgaaa gcgttccagg agagaacgca
      181 gagatacaag gaggaccagc agggattaaa ctgctctgtg gccaacaccc cacccctgaa
      241 gcccatctgt tctgaggaca cggtcctgtg ggtgttgcat gagtatgcca agaagtacca
      301 ccccctgact ctggaatgca aaaacgagaa gaaaccgctg caggagcccc ctatccctgg
      361 ctgggcaggc tacctgccca gagctagggt cactgaattt ggctatgcca caaggtatac
      421 catcatggcc aaaaagtgct acaaggactt cctggatttg gtggagcaag ccaagagggc
      481 tcagctgaag ccatatgagc aaacatacga tgtgagggct gcccagcctc ttagcccttc
      541 ttcaaaaatc ttgcagctgc aaggtctctc acccgcattt ccagaattct ctgggccagg
      601 tcaaacaccc ccaagtgagg acccccaagc tcccaggccc tgtggttgtg ctcagtggtc
      661 cagccagtca tgcagcagga atgtgtatgg ggagccacca tccttagcaa aggcttttgc
      721 cgagagctag agccctgcat cctccctagg agatgtaagc ctcaagggag cacagacacc
      781 tgttgtactt gcatcaaaat cagccccctc accctctttg ggcaatgagg tgatttaata
      841 agaattcctt aactgctgcc cccagtaatt agcagtgtct cctaagacag tctgtggatt
      901 cagaggctac atctcagcgt act
//
