LOCUS       NM_011583               1249 bp    mRNA    linear   ROD 02-FEB-2024
DEFINITION  Mus musculus sperm microtubule associated protein 2 (Spmap2),
            transcript variant 1, mRNA.
ACCESSION   NM_011583
VERSION     NM_011583.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1249)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   2  (bases 1 to 1249)
  AUTHORS   Mannan,A.U., Nayernia,K., Mueller,C., Burfeind,P., Adham,I.M. and
            Engel,W.
  TITLE     Male mice lacking the Theg (testicular haploid expressed gene)
            protein undergo normal spermatogenesis and are fertile
  JOURNAL   Biol Reprod 69 (3), 788-796 (2003)
   PUBMED   12748127
  REMARK    GeneRIF: Deletion of either the C-terminal or N-terminal regions of
            the Theg protein did not affect spermatogenesis or fertility in the
            mouse.
REFERENCE   3  (bases 1 to 1249)
  AUTHORS   Yanaka,N., Kobayashi,K., Wakimoto,K., Yamada,E., Imahie,H., Imai,Y.
            and Mori,C.
  TITLE     Insertional mutation of the murine kisimo locus caused a defect in
            spermatogenesis
  JOURNAL   J Biol Chem 275 (20), 14791-14794 (2000)
   PUBMED   10747865
REFERENCE   4  (bases 1 to 1249)
  AUTHORS   Mannan,A., Lucke,K., Dixkens,C., Neesen,J., Kamper,M., Engel,W. and
            Burfeind,P.
  TITLE     Alternative splicing, chromosome assignment and subcellular
            localization of the testicular haploid expressed gene (THEG)
  JOURNAL   Cytogenet Cell Genet 91 (1-4), 171-179 (2000)
   PUBMED   11173852
REFERENCE   5  (bases 1 to 1249)
  AUTHORS   Nayernia,K., von Mering,M.H., Kraszucka,K., Burfeind,P.,
            Wehrend,A., Kohler,M., Schmid,M. and Engel,W.
  TITLE     A novel testicular haploid expressed gene (THEG) involved in mouse
            spermatid-sertoli cell interaction
  JOURNAL   Biol Reprod 60 (6), 1488-1495 (1999)
   PUBMED   10330110
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC050970.1, AJ011834.1 and AK017058.1.
            
            [WARNING] On Apr 1, 2024 this sequence was replaced by NM_011583.4.
            
            On Apr 20, 2006 this sequence version replaced NM_011583.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ011834.1, AB033128.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849375,
                                           SAMN00849381 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-477               BC050970.1         2-478
            478-799             AJ011834.1         663-984
            800-1249            AK017058.1         718-1167
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 39.72 cM"
     gene            1..1249
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /note="sperm microtubule associated protein 2"
                     /db_xref="GeneID:21830"
                     /db_xref="MGI:MGI:1338756"
     exon            1..357
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..1198
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /note="isoform 1 is encoded by transcript variant 1;
                     testicular haploid expressed gene product; testicular
                     haploid expressed gene protein"
                     /codon_start=1
                     /product="sperm microtubule associated protein 2 isoform
                     1"
                     /protein_id="NP_035713.1"
                     /db_xref="CCDS:CCDS23977.1"
                     /db_xref="GeneID:21830"
                     /db_xref="MGI:MGI:1338756"
                     /translation="MGELGEHRASLLSNPIPEVKTLGELKQGQNNGNLDLESEPFGSH
                     WLQGSKATTGRTSEEPEEEIPPEEMAGEELPETSNLDGPLQQDLEVEVVEMSHLSITE
                     RTPSVSTAKGRKKRSRRLLELAKPKTNWQCLRDRTGRCCKGYAWISPRKTNLQFCLYW
                     PSVYWTERFIEDTTLTITVPVVSQRMEELSRPKRFYQEYYNNNRTTPIWSIPRSTLEY
                     QASNRLKQLATPKVRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRPPATLLEEW
                     DPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLDVTKNAVASSRIISLAQP
                     KIRKDLNEGYNPYYISPASLVAQASPRIYELATPKYITKKV"
     exon            358..477
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
     exon            478..549
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
     exon            550..611
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
     exon            612..681
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
     exon            682..799
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
     exon            800..959
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
     exon            960..1249
                     /gene="Spmap2"
                     /gene_synonym="Theg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggcaacca taggtccatt tgggtgctga gggagggagt gaggttaaag ggttaggagg
       61 ggcagtacac atgggggaac ttggtgaaca ccgggccagt ttgctcagta acccaatccc
      121 ggaggtcaag actttgggag agttaaagca gggacagaac aatggcaatt tggaccttga
      181 gagcgagcca tttgggagcc attggttgca gggctctaag gccactacag ggcgaacctc
      241 agaagaacca gaggaggaaa tccccccaga ggagatggct ggggaagagc tcccggagac
      301 ctccaatctg gatggtcctc ttcaacaaga cctggaggtg gaagtggttg aaatgagcca
      361 tctgtccatc actgagcgga ctcccagtgt ctccacagcc aagggcagga aaaagaggag
      421 ccggaggctg ctggagctgg cgaagcctaa gaccaactgg caatgtctga gagacaggac
      481 ggggcgctgt tgtaagggct atgcctggat ttccccacgc aagaccaact tgcagttctg
      541 cctgtattgg ccttctgtat actggaccga gcgatttatc gaggacacca cgttgaccat
      601 cacggtccct gtggtgtccc agcgcatgga ggagctttcg aggcccaagc ggttctacca
      661 ggaatattac aacaataaca ggacaacgcc catctggtcc atccctcggt ccactctgga
      721 gtaccaagct tctaaccggc tgaagcaact ggctaccccg aaggttcgca ataacatctg
      781 gagcattaac atgtctgagg tttcccaagt ctccagagca gcccagatgg cagtcccgac
      841 cccacggacg cttcggctgg caaagcccag gcccccagcc actctgttgg aagagtggga
      901 ccctatgcca aaacccaagc cttacgtgtc agactataac cgccttcttc agctggcaac
      961 acccaaggcc ctgtcagaaa agtgcgttcc tgatcgcagt cctcagtggg aggtcctgga
     1021 tgtcaccaag aacgcggtgg ccagttcacg gatcatctcc ctggcccagc ccaaaattcg
     1081 aaaggacctc aacgagggct acaacccata ctacatctcc ccagcctctc tggtggctca
     1141 ggcatctcct cgaatttatg agcttgccac ccccaaatac atcaccaaga aagtgtgaca
     1201 accaagcctt ctctccagct cacccccagt aaacaccaag tgcatcctc
//
