LOCUS       NM_183123                593 bp    mRNA    linear   ROD 05-FEB-2024
DEFINITION  Mus musculus serine protease inhibitor, Kazal type-like (Spinkl),
            mRNA.
ACCESSION   NM_183123 XR_035343 XR_035394
VERSION     NM_183123.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Tseng,H.C., Lee,R.K., Hwu,Y.M., Lu,C.H., Lin,M.H. and Li,S.H.
  TITLE     Mechanisms underlying the inhibition of murine sperm capacitation
            by the seminal protein, SPINKL
  JOURNAL   J Cell Biochem 114 (4), 888-898 (2013)
   PUBMED   23097296
  REMARK    GeneRIF: SPINKL's binding to ejaculated sperm in the uterus but not
            in the oviduct suggest that SPINKL serves as a sperm protector in
            the uterus by preventing premature capacitation.
REFERENCE   2  (bases 1 to 593)
  AUTHORS   Lin,M.H., Lee,R.K., Hwu,Y.M., Lu,C.H., Chu,S.L., Chen,Y.J.,
            Chang,W.C. and Li,S.H.
  TITLE     SPINKL, a Kazal-type serine protease inhibitor-like protein
            purified from mouse seminal vesicle fluid, is able to inhibit sperm
            capacitation
  JOURNAL   Reproduction 136 (5), 559-571 (2008)
   PUBMED   18715980
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK020535.1.
            
            On or before Jul 2, 2009 this sequence version replaced
            XR_035343.1, XR_035394.1, NM_183123.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK020535.1, BB873722.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-593               AK020535.1         2-594
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 23.74 cM"
     gene            1..593
                     /gene="Spinkl"
                     /gene_synonym="9530002K18Rik"
                     /note="serine protease inhibitor, Kazal type-like"
                     /db_xref="GeneID:77424"
                     /db_xref="MGI:MGI:1924674"
     exon            1..44
                     /gene="Spinkl"
                     /gene_synonym="9530002K18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            45..115
                     /gene="Spinkl"
                     /gene_synonym="9530002K18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            116..162
                     /gene="Spinkl"
                     /gene_synonym="9530002K18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            163..278
                     /gene="Spinkl"
                     /gene_synonym="9530002K18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            279..593
                     /gene="Spinkl"
                     /gene_synonym="9530002K18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      573..578
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Spinkl"
                     /gene_synonym="9530002K18Rik"
                     /note="putative"
ORIGIN      
        1 tgtttgagga ggcaaaagaa tcagaacgag cagtaagcac agagatttga taaaatgtcc
       61 tcaacatgga tcaaatttct ttttattctg actttggtgc ttcttcctta ttctgtgttt
      121 tcagtgaata tctttgcagg tccagagaat gttattaaag agccaaattg caccatgtat
      181 aagagtaaat ctgagtgctc caatatcgct gagaacccag tttgtgcaga tgatagaaat
      241 acatattaca atgagtgtta cttctgcata gaaaaagtag tggaaaaact taaatatagg
      301 tatcatggta tttgtattta taaataatgg tttcatggtg cttcatacaa tcaagtggaa
      361 tgttctcaac cagggcctta aattcctaac caacaaatga agtcttctat tatacattat
      421 gtggaataca gaagattgaa gaatatttcc aatgagaaca aggaactgaa tgattttatt
      481 ttcaatgatt tgagggtgat gtgaatactt gttttcttta tttttgtctt atgttacata
      541 aactgtgagt tttaatcata gatattctaa tcaataaaat gttaaataat ctc
//
