LOCUS       NM_001168423             795 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus serine peptidase inhibitor, Kazal type 13 (Spink13),
            mRNA.
ACCESSION   NM_001168423
VERSION     NM_001168423.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 795)
  AUTHORS   Ma,L., Yu,H., Ni,Z., Hu,S., Ma,W., Chu,C., Liu,Q. and Zhang,Y.
  TITLE     Spink13, an epididymis-specific gene of the Kazal-type serine
            protease inhibitor (SPINK) family, is essential for the acrosomal
            integrity and male fertility
  JOURNAL   J Biol Chem 288 (14), 10154-10165 (2013)
   PUBMED   23430248
  REMARK    GeneRIF: Spink13, an epididymis-specific gene of the Kazal-type
            serine protease inhibitor (SPINK) family, is essential for the
            acrosomal integrity and male fertility
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK139149.1.
            
            On Dec 29, 2010 this sequence version replaced NM_001168423.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK139149.1, CJ058762.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164136, SAMN01164137
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-795               AK139149.1         2-796
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 35.37 cM"
     gene            1..795
                     /gene="Spink13"
                     /gene_synonym="Gm10534; Spink5l3"
                     /note="serine peptidase inhibitor, Kazal type 13"
                     /db_xref="GeneID:100038417"
                     /db_xref="MGI:MGI:3642511"
     exon            1..291
                     /gene="Spink13"
                     /gene_synonym="Gm10534; Spink5l3"
                     /inference="alignment:Splign:2.1.0"
     exon            292..387
                     /gene="Spink13"
                     /gene_synonym="Gm10534; Spink5l3"
                     /inference="alignment:Splign:2.1.0"
     CDS             309..602
                     /gene="Spink13"
                     /gene_synonym="Gm10534; Spink5l3"
                     /note="serine protease inhibitor Kazal-type 13; serine
                     protease inhibitor Kazal-type 5-like 3"
                     /codon_start=1
                     /product="serine protease inhibitor Kazal-type 13
                     precursor"
                     /protein_id="NP_001161895.1"
                     /db_xref="CCDS:CCDS50305.1"
                     /db_xref="GeneID:100038417"
                     /db_xref="MGI:MGI:3642511"
                     /translation="MKRSGCWHQRMLLSLVLLTWTHVTFSALIRSHNFSRWPKPPCKM
                     YYPIDPDYEANCPDVKAYVCATNGLTYKNECFFCIDRWEFGPHIQFVKYGKCE"
     exon            388..425
                     /gene="Spink13"
                     /gene_synonym="Gm10534; Spink5l3"
                     /inference="alignment:Splign:2.1.0"
     exon            426..553
                     /gene="Spink13"
                     /gene_synonym="Gm10534; Spink5l3"
                     /inference="alignment:Splign:2.1.0"
     exon            554..795
                     /gene="Spink13"
                     /gene_synonym="Gm10534; Spink5l3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaatgacat ttgttcatgc cggcagcaag cccagccagt tggcaggggc ccctctgcaa
       61 taaaatatta ataataatga aaaaacagcc tttttatcat ctgaggtatt tgtagcagat
      121 tctctgagta actttcttca ctcccttatt cattcatgtt gtggggaata tattggattc
      181 catcttctca gagccctgtg gggagacatt gtgatggctt ccctccagca agccttggca
      241 ttctccagct atacactgtt atttgattaa ggatttggcg tggaagctaa gtcgtcatca
      301 aagaagccat gaaaagaagt ggctgttggc accagaggat gctgctctcc ctcgtacttt
      361 tgacttggac acatgttact ttttcagcgc ttatcagatc acataacttt tctcgatggc
      421 ctaagccccc atgcaaaatg tattacccaa tagaccctga ttatgaagct aactgtccag
      481 atgtgaaagc atatgtttgt gctaccaatg gcttgaccta caagaatgag tgcttctttt
      541 gcattgatcg gtgggagttt ggacctcaca tccagtttgt caaatatgga aagtgtgaat
      601 agtggttaac ggaacacctt catttgctta ctcctttcat tacttcattc tggggattat
      661 ttctttggga atttgaggcg tttgatttgc caattttatt catctctgtg ccatacccaa
      721 atttcaagcc aaatggaaaa caaaagagtc gaaaaatgag aaaaaggtca tatttgttgc
      781 aaataaacat ctgaa
//
